Heterogeneous alleles comprising G6PD deficiency trait in West Africa exert contrasting effects on two major clinical presentations of severe malaria

Malaria Journal

Volumn 15, Issue 1, 2016, Pages

  Shah, Shivang S ^a,d   Rockett, Kirk A ^a   Jallow, Muminatou ^b   Sisay Joof, Fatou ^b   Bojang, Kalifa A ^b   Pinder, Margaret ^b   Jeffreys, Anna ^a   Craik, Rachel ^a   Hubbart, Christina ^a   Wellems, Thomas E ^d   Kwiatkowski, Dominic P ^a,c  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b MEDICAL RESEARCH COUNCIL LABORATORIES   (Gambia)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^d NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

G6PD deficiency; malaria

Indexed keywords

GLUCOSE 6 PHOSPHATE; HEMOGLOBIN; GLUCOSE 6 PHOSPHATE DEHYDROGENASE;

AFRICA; ARTICLE; BLOOD SMEAR; BRAIN MALARIA; CONTROLLED STUDY; DISEASE SEVERITY; DNA POLYMORPHISM; ENZYME DEFICIENCY; FEMALE; GAMBIA; GENETIC HETEROGENEITY; GENETIC VARIABILITY; GENOTYPING TECHNIQUE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE DEFICIENCY; HEMIZYGOTE; HUMAN; MAJOR CLINICAL STUDY; MALARIA; MALE; PROTEIN EXPRESSION; SEVERE MALARIAL ANEMIA; WEST AFRICA; ADULT; ALLELE; CASE CONTROL STUDY; ENZYMOLOGY; GENETIC ASSOCIATION STUDY; GENETIC POLYMORPHISM; GENETICS; MIDDLE AGED;

ADULT; AFRICA, WESTERN; ALLELES; CASE-CONTROL STUDIES; FEMALE; GENETIC ASSOCIATION STUDIES; GLUCOSEPHOSPHATE DEHYDROGENASE; HUMANS; MALARIA; MALE; MIDDLE AGED; POLYMORPHISM, GENETIC;

EID: 84953276502     PISSN: None     EISSN: 14752875     Source Type: Journal    
DOI: 10.1186/s12936-015-1045-0     Document Type: Article

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