The Unsung Hero: Role of Thiamine in the ‘Vitamin C Cocktail’

Chest

Volumn 152, Issue 3, 2017, Pages 678-

  Gritsenko, Diana ^a   Papadopoulos, John ^b   Altshuler, Diana ^b   Lee, Young Im ^a   Altshuler, Jerry ^c  

^a BETH ISRAEL MEDICAL CENTER   (United States)

^b NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^c MOUNT SINAI HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASCORBIC ACID; CORTICOSTEROID; THIAMINE; HYDROCORTISONE;

ACUTE KIDNEY FAILURE; COMBINATION DRUG THERAPY; CRITICALLY ILL PATIENT; DRUG EFFECT; DRUG EFFICACY; HUMAN; LETTER; MORTALITY RISK; POST HOC ANALYSIS; PRIORITY JOURNAL; RENAL REPLACEMENT THERAPY; SECONDARY ANALYSIS; SEPSIS; SEPTIC SHOCK; SURVIVAL RATE; THIAMINE DEFICIENCY; VITAMIN SUPPLEMENTATION; EPIDEMIOLOGY; RETROSPECTIVE STUDY;

ASCORBIC ACID; CONTROLLED BEFORE-AFTER STUDIES; HUMANS; HYDROCORTISONE; RETROSPECTIVE STUDIES; SEPSIS; SHOCK, SEPTIC; THIAMINE;

EID: 85028984801     PISSN: 00123692     EISSN: 19313543     Source Type: Journal    
DOI: 10.1016/j.chest.2017.06.020     Document Type: Letter

References (5)

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2. Annane, D., Sebille, V., Charpentier, C., et al. Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock. JAMA 288:7 (2002), 862–871.
3. Collie JT, Greaves RF, Jones OA, Lam Q, Eastwood GM, Bellomo R. Vitamin B1 in critically ill patents: needs and challenges [published online ahead of print April 22, 2017]. Clin Chem Lab Med. http://dx.doi.org/10.1515/cclm-2017-0054.
4. Donnino, M.W., Andersen, L.W., Chase, M., et al., Center for Resuscitation Science Research Group. Randomized, double-blind, placebo-controlled trial of thiamine as a metabolic resuscitator in septic shock: a pilot study. Crit Care Med 44:2 (2016), 360–367.
5. Moskowitz, A., Andersen, L.W., Cocchi, M.N., Karlsson, M., Patel, P.V., Donnino, M.W., Thiamine as a renal protective agent in septic shock: a secondary analysis of a randomized, double-blind, placebo-controlled trial. Ann Am Thorac Soc 14:5 (2017), 737–741.