Anti-CD47 antibodies induce phagocytosis of live, malignant B cells by macrophages via the Fc domain, resulting in cell death by phagoptosis

Oncotarget

Volumn 8, Issue 37, 2017, Pages 60892-60903

  Métayer, Lucy E ^a   Vilalta, Anna ^a   Amos Burke, G A ^a   Brown, Guy C ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

Author keywords

Antibodies; Cell death; Leukemia; Phagocytosis; Phagoptosis

Indexed keywords

CD19 ANTIGEN; CD47 ANTIGEN; COMMON ACUTE LYMPHOBLASTIC LEUKEMIA ANTIGEN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY B6H12; UNCLASSIFIED DRUG;

697 CELL LINE; ANTIBODY INDUCED PHAGOCYTOSIS; ANTIGEN BINDING; ANTIGEN EXPRESSION; ARTICLE; B LYMPHOCYTE; BINDING AFFINITY; BINDING SITE; CANCER CELL LINE; CELL DEATH; CELL PROTECTION; CELL SURFACE; CELL VIABILITY; CHILD; CONTROLLED STUDY; DG 75 CELL LINE; FC DOMAIN; HUMAN; HUMAN CELL; INCUBATION TIME; INTRACELLULAR SIGNALING; LYMPHOBLAST; MACROPHAGE; MALE; MALIGNANT B LYMPHOCYTE; MITOCHONDRIAL MEMBRANE POTENTIAL; PHAGOCYTOSIS; PHAGOPTOSIS; PROTEIN DOMAIN; RAMOS CELL LINE; SCHOOL CHILD;

EID: 85028760393     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.18492     Document Type: Article

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