Deciphering the significance of the T-cell response to Staphylococcus aureus

Future Microbiology

Volumn 12, Issue 12, 2017, Pages 1023-1026

  Bekeredjian Ding, Isabelle ^a  

^a PAUL EHRLICH INSTITUT   (Germany)

Author keywords

Commensals; Immunity; Nosocomial infections; Staphylococcus aureus; T cells; Vaccines

Indexed keywords

VACCINE; STAPHYLOCOCCUS VACCINE;

CD8+ T LYMPHOCYTE; INFLAMMATION; NONHUMAN; PRIORITY JOURNAL; REGULATORY T LYMPHOCYTE; REVIEW; STAPHYLOCOCCUS AUREUS; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; ANIMAL; HUMAN; IMMUNOLOGY; ISOLATION AND PURIFICATION; LYMPHOCYTE ACTIVATION; STAPHYLOCOCCUS INFECTION; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; HUMANS; LYMPHOCYTE ACTIVATION; STAPHYLOCOCCAL INFECTIONS; STAPHYLOCOCCAL VACCINES; STAPHYLOCOCCUS AUREUS; T-LYMPHOCYTE SUBSETS;

EID: 85028759814     PISSN: 17460913     EISSN: 17460921     Source Type: Journal    
DOI: 10.2217/fmb-2017-0138     Document Type: Review

References (20)

1. Broker BM, Holtfreter S, Bekeredjian-Ding I. Immune control of Staphylococcus aureus - regulation and counter-regulation of the adaptive immune response. Int. J. Med. Microbiol. 304(2), 204-214 (2014).
2. Shaler CR, Choi J, Rudak PT et al. MAIT cells launch a rapid, robust and distinct hyperinflammatory response to bacterial superantigens and quickly acquire an anergic phenotype that impedes their cognate antimicrobial function: Defining a novel mechanism of superantigen-induced immunopathology and immunosuppression. PLoS Biol. 15(6), e2001930 (2017).
3. Mancini F, Monaci E, Lofano G et al. One dose of Staphylococcus aureus 4C-staph vaccine formulated with a novel TLR7-dependent adjuvant rapidly protects mice through antibodies, effector CD4+ T cells, and IL-17A. PLoS ONE 11(1), e0147767 (2016).
4. Montgomery CP, Daniels M, Zhao F, Alegre ML, Chong AS, Daum RS. Protective immunity against recurrent Staphylococcus aureus skin infection requires antibody and interleukin-17A. Infect. Immun. 82(5), 2125-2134 (2014).
5. Joshi A, Pancari G, Cope L et al. Immunization with Staphylococcus aureus iron regulated surface determinant B (IsdB) confers protection via Th17/IL17 pathway in a murine sepsis model. Hum. Vaccin. Immunother. 8(3), 336-346 (2012).
6. Maher BM, Mulcahy ME, Murphy AG et al. Nlrp-3-driven interleukin 17 production by gammadelta T cells controls infection outcomes during Staphylococcus aureus surgical site infection. Infect. Immun. 81(12), 4478-4489 (2013).
7. Cho JS, Pietras EM, Garcia NC et al. IL-17 is essential for host defense against cutaneous Staphylococcus aureus infection in mice. J. Clin. Invest. 120(5), 1762-1773 (2010).
8. Doisne JM, Soulard V, Becourt C et al. Cutting edge: Crucial role of IL-1 and IL-23 in the innate IL-17 response of peripheral lymph node NK1.1- invariant NKT cells to bacteria. J. Immunol. 186(2), 662-666 (2011).
9. Kwiecinski J, Rhost S, Lofbom L et al. Sulfatide attenuates experimental Staphylococcus aureus sepsis through a CD1d-dependent pathway. Infect. Immun. 81(4), 1114-1120 (2013).
10. Brown AF, Murphy AG, Lalor SJ et al. Memory Th1 cells are protective in invasive Staphylococcus aureus infection. PLoS Pathog. 11(11), e1005226 (2015).
11. Prabhakara R, Harro JM, Leid JG, Keegan AD, Prior ML, Shirtliff ME. Suppression of the inflammatory immune response prevents the development of chronic biofilm infection due to methicillin-resistant Staphylococcus aureus. Infect. Immun. 79(12), 5010-5018 (2011).
12. Stentzel S, Teufelberger A, Nordengrun M et al. Staphylococcal serine protease-like proteins are pacemakers of allergic airway reactions to Staphylococcus aureus. J. Allergy Clin. Immunol. 139(2), 492-500 (2017).
13. Warner JA, Mcgirt LY, Beck LA. Biomarkers of Th2 polarity are predictive of staphylococcal colonization in subjects with atopic dermatitis. Br. J. Dermatol. 160(1), 183-185 (2009).
14. Mandron M, Aries MF, Brehm RD et al. Human dendritic cells conditioned with Staphylococcus aureus enterotoxin B promote TH2 cell polarization. J. Allergy Clin. Immunol. 117(5), 1141-1147 (2006).
15. Patou J, Gevaert P, Van Zele T, Holtappels G, Van Cauwenberge P, Bachert C. Staphylococcus aureus enterotoxin B, protein A, and lipoteichoic acid stimulations in nasal polyps. J. Allergy Clin. Immunol. 121(1), 110-115 (2008).
16. Uebele J, Stein C, Nguyen MT et al. Antigen delivery to dendritic cells shapes human CD4+ and CD8+ T cell memory responses to Staphylococcus aureus. PLoS Pathog. 13(5), e1006387 (2017).
17. Taylor AL, Llewelyn MJ. Superantigen-induced proliferation of human CD4 CD25- T cells is followed by a switch to a functional regulatory phenotype. J. Immunol. 185(11), 6591-6598 (2010).
18. Stern A, Wold AE, Ostman S. Neonatal mucosal immune stimulation by microbial superantigen improves the tolerogenic capacity of CD103(+) dendritic cells. PLoS ONE 8(9), e75594 (2013).
19. Laborel-Preneron E, Bianchi P, Boralevi F et al. Effects of the Staphylococcus aureus and Staphylococcus epidermidis secretomes isolated from the skin microbiota of atopic children on CD4+ T-cell activation. PLoS ONE 10(10), e0141067 (2015).
20. Tilahun AY, Chowdhary VR, David CS, Rajagopalan G. Systemic inflammatory response elicited by superantigen destabilizes T regulatory cells, rendering them ineffective during toxic shock syndrome. J. Immunol. 193(6), 2919-2930 (2014).