Design and rationale of the Procalcitonin Antibiotic Consensus Trial (ProACT), a multicenter randomized trial of procalcitonin antibiotic guidance in lower respiratory tract infection

BMC Emergency Medicine

Volumn 17, Issue 1, 2017, Pages

  Huang, David T ^a,b   Angus, Derek C ^a,b   Chang, Chung Chou H ^a,c   Doi, Yohei ^c   Fine, Michael J ^c,d   Kellum, John A ^a   Peck Palmer, Octavia M ^a,c   Pike, Francis ^e   Weissfeld, Lisa A ^f   Yabes, Jonathan ^c   Yealy, Donald M ^a,b   Donnino, M ^g   Hou, P ^g   Sherwin, R ^g   Holst, J ^g   Rafferty, C ^g   Rodgers, D ^g   Dachman, W ^g   LoVecchio, F ^g   Filbin, M ^g   Hammel, J ^g   Exline, M ^g   Southerland, L ^g   Kurz, M ^g   McCullum, D ^g   Lotfipour, S ^g   Wilkerson, G ^g   Prunty, H ^g   Suffoletto, B ^g   Brown, A ^g   Jovin, F ^g   more..

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b The MACRO (Multidisciplinary Acute Care Research Organization) Center   (United States)

^c UNIVERSITY OF PITTSBURGH   (United States)

^d VETERANS AFFAIRS MEDICAL CENTER   (United States)

^e ELI LILLY AND COMPANY   (United States)

^f University of Iowa   (United States)

^g VA Pittsburgh Healthcare System ^*

Author keywords

Anti bacterial agents; Biomarkers; Clinical trial; Methods (MeSH); Procalcitonin; Respiratory tract infections

Indexed keywords

PROCALCITONIN; ANTIINFECTIVE AGENT; BIOLOGICAL MARKER; CALCITONIN; CALCITONIN GENE RELATED PEPTIDE; PROTEIN PRECURSOR;

ADULT; ANTIBIOTIC THERAPY; ARTICLE; CLINICAL DECISION MAKING; CLINICAL EFFECTIVENESS; CONTROLLED STUDY; DRUG EFFICACY; HUMAN; LOWER RESPIRATORY TRACT INFECTION; MAJOR CLINICAL STUDY; MULTICENTER STUDY; OUTCOME ASSESSMENT; PRESCRIPTION; RANDOMIZED CONTROLLED TRIAL; STUDY DESIGN; TREATMENT PLANNING; UNITED STATES; BLOOD; CLINICAL TRIAL; DECISION MAKING; FEMALE; HOSPITAL EMERGENCY SERVICE; MALE; METHODOLOGY; PRACTICE GUIDELINE; RESPIRATORY TRACT INFECTION; TREATMENT OUTCOME;

ANTI-BACTERIAL AGENTS; BIOMARKERS; CALCITONIN; CALCITONIN GENE-RELATED PEPTIDE; DECISION MAKING; EMERGENCY SERVICE, HOSPITAL; FEMALE; HUMANS; MALE; OUTCOME AND PROCESS ASSESSMENT (HEALTH CARE); PRACTICE GUIDELINES AS TOPIC; PROTEIN PRECURSORS; RESEARCH DESIGN; RESPIRATORY TRACT INFECTIONS; TREATMENT OUTCOME; UNITED STATES;

EID: 85028558240     PISSN: None     EISSN: 1471227X     Source Type: Journal    
DOI: 10.1186/s12873-017-0138-1     Document Type: Article

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