Information leaflet and antibiotic prescribing strategies for acute lower respiratory tract infection: A randomized controlled trial

JAMA

Volumn 293, Issue 24, 2005, Pages 3029-3035

  Little, Paul ^a   Rumsby, Kate ^a   Kelly, Joanne ^a   Watson, Louise ^a   Moore, Michael ^c   Warner, Gregory ^b   Fahey, Tom ^c,d   Williamson, Ian ^a  

^a UNIVERSITY OF SOUTHAMPTON   (United Kingdom)

^b Nightingale Surgery   (United Kingdom)

^c Three Swans' Surgery   (United Kingdom)

^d UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; ANTIBIOTIC AGENT; ERYTHROMYCIN; ANTIINFECTIVE AGENT;

ARTICLE; CLINICAL FEATURE; CLINICAL TRIAL; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COUGHING; DISEASE COURSE; DISEASE SEVERITY; DRUG EFFICACY; HUMAN; LOWER RESPIRATORY TRACT INFECTION; MEDICAL PRACTICE; PATIENT EDUCATION; PATIENT SATISFACTION; PHYSICIAN; PRESCRIPTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; ACUTE DISEASE; ADOLESCENT; ADULT; ATTITUDE TO HEALTH; CHILD; DRUG UTILIZATION; GENERAL PRACTICE; MIDDLE AGED; PATHOPHYSIOLOGY; PRESCHOOL CHILD; PUBLICATION; RESPIRATORY TRACT INFECTION;

ACUTE DISEASE; ADOLESCENT; ADULT; ANTI-BACTERIAL AGENTS; ATTITUDE TO HEALTH; CHILD; CHILD, PRESCHOOL; DRUG UTILIZATION; FAMILY PRACTICE; HUMANS; MIDDLE AGED; PAMPHLETS; PATIENT EDUCATION; RESPIRATORY TRACT INFECTIONS;

EID: 20644469696     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.293.24.3029     Document Type: Article

References (34)

1. Huchon GJ, Gialdroni-Grassi G, Leophonte P, et al. Initial antibiotic therapy for lower respiratory tract infection in the community: a European survey. Eur Respir J. 1996;9:1590-1595.
2. Her Majesty's Stationery Office, Office of Population Censuses and Surveys. Morbidity Statistics From General Practice: Fourth National Study 1991. London, England: Her Majesty's Stationery Office; 1994.
3. Gonzales R, Malone D, Maselli J, Sande M. Excessive antibiotic use for acute respiratory infections in the United States. Clin Infect Dis. 2001;33:757-762.
4. Gonzales R, Bartlett J, Besser R, et al. Principles of appropriate antibiotic use for treatment of uncomplicated acute bronchitis: background. Ann Emerg Med. 2001;37:720-727.
5. Gonzales R, Sande M. Uncomplicated acute bronchitis. Ann Intern Med. 2000;133:981-989.
6. Gonzales R. A 65-year-old woman with acute cough illness and an important engagement. JAMA. 2003;289:2701-2708.
7. Smucny J, Fahey T, Becker L, Glazier R. Antibiotics for acute bronchitis. Cochrane Database Syst Rev. 2004 (4):CD000245.
8. Fahey T, Stocks N, Thomas T. Quantitative systematic review of randomised controlled trials comparing antibiotics with placebo for acute cough in adults. BMJ. 1998;316:906-910.
9. Little P, Watson L, Morgan S, Williamson I. Antibiotic prescribing and admissions with major suppurative complications of respiratory tract infections: a data linkage study. Br J Gen Pract. 2002;52:187-190, 193.
10. Price DB, Honeybourne D, Little P, et al. Communityacquired pneumonia mortality: a potential link to antibiotic prescribing trends in general practice. Respir Med. 2003;98:17-24.
11. Hopstaken R, Muris J, Knotternus J, Kester A, Rinkens P, Dinant G. Contributions of symptoms, signs, erythrocyte sedimentation rate, and C-reactive protein to a diagnosis of pneumonia in acute lower respiratory tract infection. Br J Gen Pract. 2003;53:358-364.
12. Flanders S, Stein J, Shochat G, et al. Performance of a bedside C-reactive protein test in the diagnosis of community-acquired pneumonia in adults with acute cough. Am J Med. 2004;116:529-535.
13. Melbye H, Straume B, Aasebo U, Dale K. Diagnosis of pneumonia in adults in general practice: relative importance of typical symptoms and abnormal chest signs evaluated against a radiographic reference standard. Scand J Prim Health Care. 1992;10:226-233.
14. Diehr P, Wood R, Bushyhead J. Prediction of pneumonia in outpatients with acute cough: a statistical approach. J Chronic Dis. 1984;37:215-225.
15. Little P, Williamson I, Warner G, Gould C, Gantley M, Kinmonth AL. An open randomised trial of prescribing strategies for sore throat. BMJ. 1997;314:722-727.
16. Little P, Gould C, Williamson I, Warner G, Gantley M, Kinmonth AL. Reattendance and complications in a randomised trial of prescribing strategies for sore throat: the medicalising effect of prescribing antibiotics. BMJ. 1997;315:350-352.
17. Dowell J, Pitkethly J, Bain J, Martin S. A randomised controlled trial of delayed antibiotic prescribing as a strategy for managing uncomplicated respiratory tract infection in primary care. Br J Gen Pract. 2001;51:200-205.
18. Gonzales R, Sande M. What will it take to stop physicians from prescribing antibiotics in acute bronchitis? Lancet. 1995;345:665-666.
19. Spurling G, Del Mar C, Dooley L, Foxlee R. Delayed antibiotics for symptoms and complications of respiratory infections. Cochrane Database Syst Rev. 2004(4):CD004417.
20. MacFarlane J, Holmes W, Gard P, Thornhill D, MacFarlane R, Hubbard R. Reducing antibiotic use for acute bronchitis in primary care: blinded, randomised controlled trial of patient information leaflet. BMJ. 2002;324:91-94.
21. Macfarlane JT, Holmes WF, Macfarlane RM, Lewis S. Reducing reconsultation for acute lower respiratory tract illness with an information leaflet: a randomised controlled study of patients in primary care. Br J Gen Pract. 1997;47:719-722.
22. Macfarlane JT, Colville A, Guion A. Prospective study of aetiology and outcome of adult lower respiratory tract infections in the community. Lancet. 1993;341:511-514.
23. MacFarlane J, Holmes W, Gard P, et al. Prospective study of the incidence, aetiology and outcome of adult lower respiratory tract illness in the community. Thorax. 2001;56:109-114.
24. British Thoracic Society Guidelines for the management of community acquired pneumonia in adults. Thorax. 2001;56(suppl IV):1-64.
25. Melbye H, Straume B, Aasebo U, Brox J. The diagnosis of adult pneumonia in general practice: the diagnostic value of history, physical examination and some blood tests. Scand J Prim Health Care. 1988;6:111-117.
26. Melbye H, Aaras I, Fleten N, Kolstrup N, Mikalsen J. The value of C-reactive protein testing in suspected lower respiratory tract infections: a study from general practice on the effect of a rapid test on antibiotic research and course of the disease in adults. Tidsskr Nor Laegeforen. 1995;115:1610-1615.
27. Watson L, Little P, Williamson I, Moore M, Warner G. Validation study of a diary for use in acute lower respiratory tract infection. Fam Pract. 2001;18:553-554.
28. Cornford CS. Why patients consult when they cough: a comparison of consulting and nonconsulting patients. Br J Gen Pract. 1998;48:1751-1754.
29. Little P, Somerville J, Williamson I, et al. Psychosocial, lifestyle and health status variables in predicting high attendance among adults. Br J Gen Pract. 2001;51:987-994.
30. Verheij TJ, Hermans J, Mulder JD. Effects of doxycycline in patients with acute cough and purulent sputum: a double blind placebo controlled trial. Br J Gen Pract. 1994;44:400-404.
31. House of Lords. House of Lords Select Committee on Science and Technology: 7th Report. London, England: UK Parliament; 1998.
32. SMAC. Standing Medical Advisory Committee (SMAC) Report: The Path of Least Resistance. London, England: Occasional Report, Public Health Laboratory Service; 1998.
33. Gonzales R, Steiner J, Maselli J, Lum A, Barrett P. Impact of reducing antibiotic prescribing for acute bronchitis on patient satisfaction. Eff Clin Pract. 2001;4:105-111.
34. Arroll B, Kenealy T, Kerse N. Do delayed prescriptions reduce the use of antibiotics for the common cold? a single-blind controlled trial. J Fam Pract. 2002;51:324-328.