Aloin, a component of the aloe vera plant leaf, induces pathological changes and modulates the composition of microbiota in the large intestines of F344/N Male Rats

Toxicological Sciences

Volumn 158, Issue 2, 2017, Pages 302-318

  Boudreau, Mary D ^a   Olson, Greg R ^b   Tryndyak, Volodymyr P ^a   Bryant, Matthew S ^a   Felton, Robert P ^a   Beland, Frederick A ^a  

^a NATIONAL CENTER FOR TOXICOLOGICAL RESEARCH   (United States)

^b Toxicologic Pathology Associates   (United States)

Author keywords

Aloe vera; Aloin; Food safety nutrition; Gastrointestinal; Gut microbiota; Safety evaluation; Systems toxicology

Indexed keywords

ALLOIN; EMODIN; PLANT EXTRACT;

ALOE; ANALOGS AND DERIVATIVES; ANIMAL; CHEMISTRY; COLON; DOSE RESPONSE; DRUG EFFECT; FECES; FISCHER 344 RAT; GROWTH; INTESTINE FLORA; MALE; MICROBIOLOGY; PATHOLOGY; PLANT LEAF; RAT;

ALOE; ANIMALS; COLON; DOSE-RESPONSE RELATIONSHIP, DRUG; EMODIN; FECES; GASTROINTESTINAL MICROBIOME; GROWTH; MALE; PLANT EXTRACTS; PLANT LEAVES; RATS; RATS, INBRED F344;

EID: 85028348427     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfx105     Document Type: Article

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