A phase 1 study to evaluate the safety and pharmacokinetics of MEDI8852, an anti-influenza A monoclonal antibody, in healthy adult volunteers

Biologicals

Volumn 50, Issue , 2017, Pages 81-86

  Mallory, Raburn M ^a   Ali, S Omar ^a   Takas, Therese ^a   Kankam, Martin ^b   Dubovsky, Filip ^a   Tseng, Leo ^a  

^a MEDIMMUNE   (United States)

^b Vince and Associates Clinical Research   (United States)

Author keywords

Hemagglutinin; Influenza; MEDI8852; Monoclonal antibody

Indexed keywords

DRUG ANTIBODY; MEDI 8852; MONOCLONAL ANTIBODY; PLACEBO; UNCLASSIFIED DRUG;

ADULT; AREA UNDER THE CURVE; ARTICLE; BLURRED VISION; CONTROLLED STUDY; DIARRHEA; DOUBLE BLIND PROCEDURE; DRUG CLEARANCE; DRUG DOSE ESCALATION; DRUG HALF LIFE; DRUG SAFETY; DRUG TOLERABILITY; FEMALE; GASTROENTERITIS; HEADACHE; HUMAN; HUMAN EXPERIMENT; HYPOGLYCEMIA; INFLUENZA A; LYMPHADENOPATHY; MALE; MAXIMUM PLASMA CONCENTRATION; MYALGIA; NORMAL HUMAN; NOSE OBSTRUCTION; PARESTHESIA; PHASE 1 CLINICAL TRIAL; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; URINARY TRACT INFECTION; AGED; CHEMICALLY INDUCED; CLINICAL TRIAL; DOSE RESPONSE; HALF LIFE TIME; IMMUNOLOGY; INFLUENZA; INFLUENZA A VIRUS; MIDDLE AGED; VIROLOGY;

ADULT; AGED; ANTIBODIES, MONOCLONAL; AREA UNDER CURVE; DOSE-RESPONSE RELATIONSHIP, DRUG; DOUBLE-BLIND METHOD; FEMALE; HALF-LIFE; HEADACHE; HEALTHY VOLUNTEERS; HUMANS; HYPOGLYCEMIA; INFLUENZA A VIRUS; INFLUENZA, HUMAN; MALE; MIDDLE AGED;

EID: 85028087722     PISSN: 10451056     EISSN: 10958320     Source Type: Journal    
DOI: 10.1016/j.biologicals.2017.08.007     Document Type: Article

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