메뉴 건너뛰기




Volumn 28, Issue 2, 2011, Pages 447-454

Pathobiologic implications of methylation and expression status of Runx3 and CHFR genes in gastric cancer

Author keywords

CHFR gene; Gastric cancer; Methylation; Methylation specific PCR; Runx3 gene

Indexed keywords

MESSENGER RNA; ONCOPROTEIN; PROTEIN CHECKPOINT WITH FORKHEAD AND RING FINGER; TRANSCRIPTION FACTOR RUNX3; UNCLASSIFIED DRUG;

EID: 85027940278     PISSN: 13570560     EISSN: 1559131X     Source Type: Journal    
DOI: 10.1007/s12032-010-9467-6     Document Type: Article
Times cited : (19)

References (30)
  • 2
    • 0036284631 scopus 로고    scopus 로고
    • Detection of gene promoter hypermethylation in the tumor and serum of patients with gastric carcinoma
    • 12060614 1:CAS:528:DC%2BD38Xlt1CrtLg%3D
    • TL Lee, et al. 2002 Detection of gene promoter hypermethylation in the tumor and serum of patients with gastric carcinoma Clin Cancer Res 8 1761 1766 12060614 1:CAS:528:DC%2BD38Xlt1CrtLg%3D
    • (2002) Clin Cancer Res , vol.8 , pp. 1761-1766
    • Lee, T.L.1
  • 3
    • 22044441872 scopus 로고    scopus 로고
    • Potential diagnostic and prognostic values of detecting promoter hypermethylation in the serum of patients with gastric cancer
    • DOI 10.1038/sj.bjc.6602636
    • WK Leung, et al. 2005 Potential diagnostic and prognostic values of detecting promoter hypermethylation in the serum of patients with gastric cancer Br J Cancer 92 2190 2194 15942635 10.1038/sj.bjc.6602636 1:CAS:528: DC%2BD2MXltVygtb8%3D (Pubitemid 40966256)
    • (2005) British Journal of Cancer , vol.92 , Issue.12 , pp. 2190-2194
    • Leung, W.K.1    To, K.-F.2    Chu, E.S.H.3    Chan, M.W.Y.4    Bai, A.H.C.5    Ng, E.K.W.6    Chan, F.K.L.7    Sung, J.J.Y.8
  • 4
    • 0036724347 scopus 로고    scopus 로고
    • INK4a, CDHI, and RAR-beta in intestinal, diffuse-adherent, and diffuse-scattered type gastric carcinomas
    • DOI 10.1002/path.1170
    • N Oue, et al. 2002 Distinct promoter hypermethylation of p16INK4a, CDH1, and RAR-beta in intestinal, diffuse-adherent, and diffuse-scattered type gastric carcinomas J Pathol 198 55 59 12210063 10.1002/path.1170 1:CAS:528: DC%2BD38Xns1Wiurs%3D (Pubitemid 34966207)
    • (2002) Journal of Pathology , vol.198 , Issue.1 , pp. 55-59
    • Oue, N.1    Motoshita, J.2    Yokozaki, H.3    Hayashi, K.4    Tahara, E.5    Taniyama, K.6    Matsusaki, K.7    Yasui, W.8
  • 5
    • 0037118044 scopus 로고    scopus 로고
    • Cancer: New-age tumour suppressors
    • DOI 10.1038/417235a
    • A Balmain 2002 Cancer: new-age tumour suppressors Nature 417 235 237 12015584 10.1038/417235a 1:CAS:528:DC%2BD38Xjs1agsbk%3D (Pubitemid 34534691)
    • (2002) Nature , vol.417 , Issue.6886 , pp. 235-237
    • Balmain, A.1
  • 6
    • 2342641616 scopus 로고    scopus 로고
    • Methylation of RUNX3 in various types of human cancers and premalignant stages of gastric carcinoma
    • DOI 10.1038/labinvest.3700060
    • TY Kim, et al. 2004 Methylation of RUNX3 in various types of human cancers and premalignant stages of gastric carcinoma Lab Invest 84 479 484 14968123 10.1038/labinvest.3700060 1:CAS:528:DC%2BD2cXmtF2itrk%3D (Pubitemid 41656475)
    • (2004) Laboratory Investigation , vol.84 , Issue.4 , pp. 479-484
    • Kim, T.Y.1    Lee, H.J.2    Hwang, K.S.3    Lee, M.4    Kim, J.W.5    Bang, Y.-J.6    Kang, G.H.7
  • 7
    • 46349102935 scopus 로고    scopus 로고
    • Expression of RUNX3 gene, methylation status and clinicopathological significance in breast cancer and breast cancer cell lines
    • DOI 10.1159/000132385
    • Y Jiang D Tong G Lou Y Zhang J Geng 2008 Expression of RUNX3 gene, methylation status and clinicopathological significance in breast cancer and breast cancer cell lines Pathobiology 75 244 251 18580070 10.1159/000132385 1:CAS:528:DC%2BD1cXnvFChur4%3D (Pubitemid 351918429)
    • (2008) Pathobiology , vol.75 , Issue.4 , pp. 244-251
    • Jiang, Y.1    Tong, D.2    Lou, G.3    Zhang, Y.4    Geng, J.5
  • 8
    • 58049221118 scopus 로고    scopus 로고
    • RUNX3 inactivation by frequent promoter hypermethylation and protein mislocalization constitute an early event in breast cancer progression
    • 18256927 10.1007/s10549-008-9917-4 1:CAS:528:DC%2BD1cXhsFWrs7nE
    • MM Subramaniam, et al. 2009 RUNX3 inactivation by frequent promoter hypermethylation and protein mislocalization constitute an early event in breast cancer progression Breast Cancer Res Treat 113 113 121 18256927 10.1007/s10549-008-9917-4 1:CAS:528:DC%2BD1cXhsFWrs7nE
    • (2009) Breast Cancer Res Treat , vol.113 , pp. 113-121
    • Subramaniam, M.M.1
  • 9
    • 40949161396 scopus 로고    scopus 로고
    • Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma
    • DOI 10.1002/hep.22110
    • N Nishida, et al. 2008 Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma Hepatology 47 908 918 18161048 10.1002/hep.22110 1:CAS:528:DC%2BD1cXktVOhs74%3D (Pubitemid 351449682)
    • (2008) Hepatology , vol.47 , Issue.3 , pp. 908-918
    • Nishida, N.1    Nagasaka, T.2    Nishimura, T.3    Ikai, I.4    Boland, C.R.5    Goel, A.6
  • 12
    • 0037275750 scopus 로고    scopus 로고
    • Frequent hypermethylation of the 5β CpG island of the mitotic stress checkpoint gene Chfr in colorectal and non-small cell lung cancer
    • DOI 10.1093/carcin/24.1.47
    • PG Corn, et al. 2003 Frequent hypermethylation of the 5′ CpG island of the mitotic stress checkpoint gene Chfr in colorectal and non-small cell lung cancer Carcinogenesis 24 47 51 12538348 10.1093/carcin/24.1.47 1:CAS:528:DC%2BD3sXitlCgtLo%3D (Pubitemid 36193194)
    • (2003) Carcinogenesis , vol.24 , Issue.1 , pp. 47-51
    • Corn, P.G.1    Summers, M.K.2    Fogt, F.3    Virmani, A.K.4    Gazdar, A.F.5    Halazonetis, T.D.6    El-Deiry, W.S.7
  • 13
    • 0034721154 scopus 로고    scopus 로고
    • Chfr defines a mitotic stress checkpoint that delays entry into metaphase
    • DOI 10.1038/35019108
    • DM Scolnick TD Halazonetis 2000 Chfr defines a mitotic stress checkpoint that delays entry into metaphase Nature 406 430 435 10935642 10.1038/35019108 1:CAS:528:DC%2BD3cXlslKnu7c%3D (Pubitemid 30625565)
    • (2000) Nature , vol.406 , Issue.6794 , pp. 430-435
    • Scolnick, D.M.1    Halazonetis, T.D.2
  • 16
    • 0036799843 scopus 로고    scopus 로고
    • Chfr expression is downregulated by CpG island hypermethylation in esophageal cancer
    • 12376479 10.1093/carcin/23.10.1695 1:CAS:528:DC%2BD38XnvF2qsbo%3D
    • Y Shibata, et al. 2002 Chfr expression is downregulated by CpG island hypermethylation in esophageal cancer Carcinogenesis 23 1695 1699 12376479 10.1093/carcin/23.10.1695 1:CAS:528:DC%2BD38XnvF2qsbo%3D
    • (2002) Carcinogenesis , vol.23 , pp. 1695-1699
    • Shibata, Y.1
  • 17
    • 32944454976 scopus 로고    scopus 로고
    • Spreading of methylation within RUNX3 CpG island in gastric cancer
    • DOI 10.1111/j.1349-7006.2005.00133.x
    • N Homma, et al. 2006 Spreading of methylation within RUNX3 CpG island in gastric cancer Cancer Sci 97 51 56 16367921 10.1111/j.1349-7006.2005.00133.x 1:CAS:528:DC%2BD28Xht1Kqtrw%3D (Pubitemid 43257027)
    • (2006) Cancer Science , vol.97 , Issue.1 , pp. 51-56
    • Homma, N.1    Tamura, G.2    Honda, T.3    Matsumoto, Y.4    Nishizuka, S.5    Kawata, S.6    Motoyama, T.7
  • 18
    • 58149135006 scopus 로고    scopus 로고
    • Mechanism and pathobiologic implications of CHFR promoter methylation in gastric carcinoma
    • 18763281 10.3748/wjg.14.5000 1:CAS:528:DC%2BD1cXhsVyntLvF
    • YJ Gao Y Xin JJ Zhang J Zhou 2008 Mechanism and pathobiologic implications of CHFR promoter methylation in gastric carcinoma World J Gastroenterol 14 5000 5007 18763281 10.3748/wjg.14.5000 1:CAS:528: DC%2BD1cXhsVyntLvF
    • (2008) World J Gastroenterol , vol.14 , pp. 5000-5007
    • Gao, Y.J.1    Xin, Y.2    Zhang, J.J.3    Zhou, J.4
  • 19
  • 20
    • 31544444483 scopus 로고    scopus 로고
    • CpG island hypermethylation in progression of esophageal and gastric cancer
    • DOI 10.1002/cncr.21657
    • F Sato SJ Meltzer 2006 CpG island hypermethylation in progression of esophageal and gastric cancer Cancer 106 483 493 16362978 10.1002/cncr.21657 1:CAS:528:DC%2BD28XhsFGiurg%3D (Pubitemid 43157610)
    • (2006) Cancer , vol.106 , Issue.3 , pp. 483-493
    • Sato, F.1    Meltzer, S.J.2
  • 22
  • 23
    • 1642474373 scopus 로고    scopus 로고
    • Promoter methylation status of tumor suppressor and tumor-related genes in neoplastic and non-neoplastic gastric epithelia
    • G Tamura 2004 Promoter methylation status of tumor suppressor and tumor-related genes in neoplastic and non-neoplastic gastric epithelia Histol Histopathol 19 221 228 14702190 1:CAS:528:DC%2BD2cXjtFyrtbo%3D (Pubitemid 38111266)
    • (2004) Histology and Histopathology , vol.19 , Issue.1 , pp. 221-228
    • Tamura, G.1
  • 24
    • 2942580970 scopus 로고    scopus 로고
    • Promoter hypermethylation of the Chfr gene in neoplastic and non-neoplastic gastric epithelia
    • DOI 10.1038/sj.bjc.6601849
    • T Honda, et al. 2004 Promoter hypermethylation of the Chfr gene in neoplastic and non-neoplastic gastric epithelia Br J Cancer 90 2013 2016 15138487 10.1038/sj.bjc.6601849 1:CAS:528:DC%2BD2cXjvVals7k%3D (Pubitemid 38746346)
    • (2004) British Journal of Cancer , vol.90 , Issue.10 , pp. 2013-2016
    • Honda, T.1    Tamura, G.2    Waki, T.3    Kawata, S.4    Nishizuka, S.5    Motoyama, T.6
  • 25
    • 0038527233 scopus 로고    scopus 로고
    • Promoter methylation status of DAP-kinase and RUNX3 genes in neoplastic and non-neoplastic gastric epithelia
    • DOI 10.1111/j.1349-7006.2003.tb01447.x
    • T Waki, et al. 2003 Promoter methylation status of DAP-kinase and RUNX3 genes in neoplastic and non-neoplastic gastric epithelia Cancer Sci 94 360 364 12824905 10.1111/j.1349-7006.2003.tb01447.x 1:CAS:528:DC%2BD3sXkslCns7w%3D (Pubitemid 36626369)
    • (2003) Cancer Science , vol.94 , Issue.4 , pp. 360-364
    • Waki, T.1    Tamura, G.2    Sato, M.3    Terashima, M.4    Nishizuka, S.5    Motoyama, T.6
  • 26
    • 21644464400 scopus 로고    scopus 로고
    • Promoter hypermethylation and silencing of CHFR mitotic stress checkpoint gene in human gastric cancers
    • 15201973 1:CAS:528:DC%2BD2cXlvVeqsrs%3D
    • HC Kang, et al. 2004 Promoter hypermethylation and silencing of CHFR mitotic stress checkpoint gene in human gastric cancers Oncol Rep 12 129 133 15201973 1:CAS:528:DC%2BD2cXlvVeqsrs%3D
    • (2004) Oncol Rep , vol.12 , pp. 129-133
    • Kang, H.C.1
  • 28
    • 41349097718 scopus 로고    scopus 로고
    • Molecular biomarkers in urothelial bladder cancer
    • DOI 10.1111/j.1349-7006.2008.00735.x
    • WJ Kim SC Bae 2008 Molecular biomarkers in urothelial bladder cancer Cancer Sci 99 646 652 18377416 10.1111/j.1349-7006.2008.00735.x 1:CAS:528:DC%2BD1cXlsFygu70%3D (Pubitemid 351448065)
    • (2008) Cancer Science , vol.99 , Issue.4 , pp. 646-652
    • Kim, W.-J.1    Bae, S.-C.2
  • 29
    • 48649097939 scopus 로고    scopus 로고
    • Methylation of the RUNX3 promoter as a potential prognostic marker for bladder tumor
    • 18639281 10.1016/j.juro.2008.05.002 1:CAS:528:DC%2BD1cXhtVKmsbbL
    • EJ Kim, et al. 2008 Methylation of the RUNX3 promoter as a potential prognostic marker for bladder tumor J Urol 180 1141 1145 18639281 10.1016/j.juro.2008.05.002 1:CAS:528:DC%2BD1cXhtVKmsbbL
    • (2008) J Urol , vol.180 , pp. 1141-1145
    • Kim, E.J.1
  • 30
    • 34447130265 scopus 로고    scopus 로고
    • Altered expression of the early mitotic checkpoint protein, CHFR, in breast cancers: Implications for tumor suppression
    • DOI 10.1158/0008-5472.CAN-06-4109
    • LM Privette ME Gonzalez L Ding CG Kleer EM Petty 2007 Altered expression of the early mitotic checkpoint protein, CHFR, in breast cancers: implications for tumor suppression Cancer Res 67 6064 6074 17596595 10.1158/0008-5472.CAN-06- 4109 1:CAS:528:DC%2BD2sXnsVyqsb8%3D (Pubitemid 47037485)
    • (2007) Cancer Research , vol.67 , Issue.13 , pp. 6064-6074
    • Privette, L.M.1    Gonzalez, M.E.2    Ding, L.3    Kleer, C.G.4    Petty, E.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.