-
1
-
-
0035932396
-
E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma
-
DOI 10.1038/sj.onc.1204234
-
JC Machado, et al. 2001 E-cadherin gene (CDH1) promoter methylation as the second hit in sporadic diffuse gastric carcinoma Oncogene 20 1525 1528 11313896 10.1038/sj.onc.1204234 1:CAS:528:DC%2BD3MXis1Kltrs%3D (Pubitemid 32291203)
-
(2001)
Oncogene
, vol.20
, Issue.12
, pp. 1525-1528
-
-
Machado, J.C.1
Oliveira, C.2
Carvalho, R.3
Soares, P.4
Berx, G.5
Caldas, C.6
Seruca, R.7
Carneiro, F.8
Sobrinho-Simoes, M.9
-
2
-
-
0036284631
-
Detection of gene promoter hypermethylation in the tumor and serum of patients with gastric carcinoma
-
12060614 1:CAS:528:DC%2BD38Xlt1CrtLg%3D
-
TL Lee, et al. 2002 Detection of gene promoter hypermethylation in the tumor and serum of patients with gastric carcinoma Clin Cancer Res 8 1761 1766 12060614 1:CAS:528:DC%2BD38Xlt1CrtLg%3D
-
(2002)
Clin Cancer Res
, vol.8
, pp. 1761-1766
-
-
Lee, T.L.1
-
3
-
-
22044441872
-
Potential diagnostic and prognostic values of detecting promoter hypermethylation in the serum of patients with gastric cancer
-
DOI 10.1038/sj.bjc.6602636
-
WK Leung, et al. 2005 Potential diagnostic and prognostic values of detecting promoter hypermethylation in the serum of patients with gastric cancer Br J Cancer 92 2190 2194 15942635 10.1038/sj.bjc.6602636 1:CAS:528: DC%2BD2MXltVygtb8%3D (Pubitemid 40966256)
-
(2005)
British Journal of Cancer
, vol.92
, Issue.12
, pp. 2190-2194
-
-
Leung, W.K.1
To, K.-F.2
Chu, E.S.H.3
Chan, M.W.Y.4
Bai, A.H.C.5
Ng, E.K.W.6
Chan, F.K.L.7
Sung, J.J.Y.8
-
4
-
-
0036724347
-
INK4a, CDHI, and RAR-beta in intestinal, diffuse-adherent, and diffuse-scattered type gastric carcinomas
-
DOI 10.1002/path.1170
-
N Oue, et al. 2002 Distinct promoter hypermethylation of p16INK4a, CDH1, and RAR-beta in intestinal, diffuse-adherent, and diffuse-scattered type gastric carcinomas J Pathol 198 55 59 12210063 10.1002/path.1170 1:CAS:528: DC%2BD38Xns1Wiurs%3D (Pubitemid 34966207)
-
(2002)
Journal of Pathology
, vol.198
, Issue.1
, pp. 55-59
-
-
Oue, N.1
Motoshita, J.2
Yokozaki, H.3
Hayashi, K.4
Tahara, E.5
Taniyama, K.6
Matsusaki, K.7
Yasui, W.8
-
5
-
-
0037118044
-
Cancer: New-age tumour suppressors
-
DOI 10.1038/417235a
-
A Balmain 2002 Cancer: new-age tumour suppressors Nature 417 235 237 12015584 10.1038/417235a 1:CAS:528:DC%2BD38Xjs1agsbk%3D (Pubitemid 34534691)
-
(2002)
Nature
, vol.417
, Issue.6886
, pp. 235-237
-
-
Balmain, A.1
-
6
-
-
2342641616
-
Methylation of RUNX3 in various types of human cancers and premalignant stages of gastric carcinoma
-
DOI 10.1038/labinvest.3700060
-
TY Kim, et al. 2004 Methylation of RUNX3 in various types of human cancers and premalignant stages of gastric carcinoma Lab Invest 84 479 484 14968123 10.1038/labinvest.3700060 1:CAS:528:DC%2BD2cXmtF2itrk%3D (Pubitemid 41656475)
-
(2004)
Laboratory Investigation
, vol.84
, Issue.4
, pp. 479-484
-
-
Kim, T.Y.1
Lee, H.J.2
Hwang, K.S.3
Lee, M.4
Kim, J.W.5
Bang, Y.-J.6
Kang, G.H.7
-
7
-
-
46349102935
-
Expression of RUNX3 gene, methylation status and clinicopathological significance in breast cancer and breast cancer cell lines
-
DOI 10.1159/000132385
-
Y Jiang D Tong G Lou Y Zhang J Geng 2008 Expression of RUNX3 gene, methylation status and clinicopathological significance in breast cancer and breast cancer cell lines Pathobiology 75 244 251 18580070 10.1159/000132385 1:CAS:528:DC%2BD1cXnvFChur4%3D (Pubitemid 351918429)
-
(2008)
Pathobiology
, vol.75
, Issue.4
, pp. 244-251
-
-
Jiang, Y.1
Tong, D.2
Lou, G.3
Zhang, Y.4
Geng, J.5
-
8
-
-
58049221118
-
RUNX3 inactivation by frequent promoter hypermethylation and protein mislocalization constitute an early event in breast cancer progression
-
18256927 10.1007/s10549-008-9917-4 1:CAS:528:DC%2BD1cXhsFWrs7nE
-
MM Subramaniam, et al. 2009 RUNX3 inactivation by frequent promoter hypermethylation and protein mislocalization constitute an early event in breast cancer progression Breast Cancer Res Treat 113 113 121 18256927 10.1007/s10549-008-9917-4 1:CAS:528:DC%2BD1cXhsFWrs7nE
-
(2009)
Breast Cancer Res Treat
, vol.113
, pp. 113-121
-
-
Subramaniam, M.M.1
-
9
-
-
40949161396
-
Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma
-
DOI 10.1002/hep.22110
-
N Nishida, et al. 2008 Aberrant methylation of multiple tumor suppressor genes in aging liver, chronic hepatitis, and hepatocellular carcinoma Hepatology 47 908 918 18161048 10.1002/hep.22110 1:CAS:528:DC%2BD1cXktVOhs74%3D (Pubitemid 351449682)
-
(2008)
Hepatology
, vol.47
, Issue.3
, pp. 908-918
-
-
Nishida, N.1
Nagasaka, T.2
Nishimura, T.3
Ikai, I.4
Boland, C.R.5
Goel, A.6
-
10
-
-
18344389720
-
Causal relationship between the loss of RUNX3 expression and gastric cancer
-
DOI 10.1016/S0092-8674(02)00690-6
-
QL Li, et al. 2002 Causal relationship between the loss of RUNX3 expression and gastric cancer Cell 109 113 124 11955451 10.1016/S0092-8674(02) 00690-6 1:CAS:528:DC%2BD38XjtVOntLs%3D (Pubitemid 34327521)
-
(2002)
Cell
, vol.109
, Issue.1
, pp. 113-124
-
-
Li, Q.-L.1
Ito, K.2
Sakakura, C.3
Fukamachi, H.4
Inoue, K.-I.5
Chi, X.-Z.6
Lee, K.-Y.7
Nomura, S.8
Lee, C.-W.9
Han, S.-B.10
Kim, H.-M.11
Kim, W.-J.12
Yamamoto, H.13
Yamashita, N.14
Yano, T.15
Ikeda, T.16
Itohara, S.17
Inazawa, J.18
Abe, T.19
Hagiwara, A.20
Yamagishi, H.21
Ooe, A.22
Kaneda, A.23
Sugimura, T.24
Ushijima, T.25
Bae, S.-C.26
Ito, Y.27
more..
-
11
-
-
0037934421
-
Epigenetic inactivation of CHFR in human tumors
-
DOI 10.1073/pnas.1337066100
-
M Toyota, et al. 2003 Epigenetic inactivation of CHFR in human tumors Proc Natl Acad Sci USA 100 7818 7823 12810945 10.1073/pnas.1337066100 1:CAS:528:DC%2BD3sXlt1Wqsb4%3D (Pubitemid 36760053)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.13
, pp. 7818-7823
-
-
Toyota, M.1
Sasaki, Y.2
Satoh, A.3
Ogi, K.4
Kikuchi, T.5
Suzuki, H.6
Mita, H.7
Tanaka, N.8
Itoh, F.9
Issa, J.-P.J.10
Jair, K.-W.11
Schuebel, K.E.12
Imai, K.13
Tokino, T.14
-
12
-
-
0037275750
-
Frequent hypermethylation of the 5β CpG island of the mitotic stress checkpoint gene Chfr in colorectal and non-small cell lung cancer
-
DOI 10.1093/carcin/24.1.47
-
PG Corn, et al. 2003 Frequent hypermethylation of the 5′ CpG island of the mitotic stress checkpoint gene Chfr in colorectal and non-small cell lung cancer Carcinogenesis 24 47 51 12538348 10.1093/carcin/24.1.47 1:CAS:528:DC%2BD3sXitlCgtLo%3D (Pubitemid 36193194)
-
(2003)
Carcinogenesis
, vol.24
, Issue.1
, pp. 47-51
-
-
Corn, P.G.1
Summers, M.K.2
Fogt, F.3
Virmani, A.K.4
Gazdar, A.F.5
Halazonetis, T.D.6
El-Deiry, W.S.7
-
13
-
-
0034721154
-
Chfr defines a mitotic stress checkpoint that delays entry into metaphase
-
DOI 10.1038/35019108
-
DM Scolnick TD Halazonetis 2000 Chfr defines a mitotic stress checkpoint that delays entry into metaphase Nature 406 430 435 10935642 10.1038/35019108 1:CAS:528:DC%2BD3cXlslKnu7c%3D (Pubitemid 30625565)
-
(2000)
Nature
, vol.406
, Issue.6794
, pp. 430-435
-
-
Scolnick, D.M.1
Halazonetis, T.D.2
-
16
-
-
0036799843
-
Chfr expression is downregulated by CpG island hypermethylation in esophageal cancer
-
12376479 10.1093/carcin/23.10.1695 1:CAS:528:DC%2BD38XnvF2qsbo%3D
-
Y Shibata, et al. 2002 Chfr expression is downregulated by CpG island hypermethylation in esophageal cancer Carcinogenesis 23 1695 1699 12376479 10.1093/carcin/23.10.1695 1:CAS:528:DC%2BD38XnvF2qsbo%3D
-
(2002)
Carcinogenesis
, vol.23
, pp. 1695-1699
-
-
Shibata, Y.1
-
17
-
-
32944454976
-
Spreading of methylation within RUNX3 CpG island in gastric cancer
-
DOI 10.1111/j.1349-7006.2005.00133.x
-
N Homma, et al. 2006 Spreading of methylation within RUNX3 CpG island in gastric cancer Cancer Sci 97 51 56 16367921 10.1111/j.1349-7006.2005.00133.x 1:CAS:528:DC%2BD28Xht1Kqtrw%3D (Pubitemid 43257027)
-
(2006)
Cancer Science
, vol.97
, Issue.1
, pp. 51-56
-
-
Homma, N.1
Tamura, G.2
Honda, T.3
Matsumoto, Y.4
Nishizuka, S.5
Kawata, S.6
Motoyama, T.7
-
18
-
-
58149135006
-
Mechanism and pathobiologic implications of CHFR promoter methylation in gastric carcinoma
-
18763281 10.3748/wjg.14.5000 1:CAS:528:DC%2BD1cXhsVyntLvF
-
YJ Gao Y Xin JJ Zhang J Zhou 2008 Mechanism and pathobiologic implications of CHFR promoter methylation in gastric carcinoma World J Gastroenterol 14 5000 5007 18763281 10.3748/wjg.14.5000 1:CAS:528: DC%2BD1cXhsVyntLvF
-
(2008)
World J Gastroenterol
, vol.14
, pp. 5000-5007
-
-
Gao, Y.J.1
Xin, Y.2
Zhang, J.J.3
Zhou, J.4
-
19
-
-
0348223971
-
Transcription Factor Sp1 Expression Is a Significant Predictor of Survival in Human Gastric Cancer
-
L Wang, et al. 2003 Transcription factor Sp1 expression is a significant predictor of survival in human gastric cancer Clin Cancer Res 9 6371 6380 14695137 1:CAS:528:DC%2BD3sXhtVSqurzK (Pubitemid 38031822)
-
(2003)
Clinical Cancer Research
, vol.9
, Issue.17
, pp. 6371-6380
-
-
Wang, L.1
Wei, D.2
Huang, S.3
Peng, Z.4
Le, X.5
Wu, T.T.6
Yao, J.7
Ajani, J.8
Xie, K.9
-
20
-
-
31544444483
-
CpG island hypermethylation in progression of esophageal and gastric cancer
-
DOI 10.1002/cncr.21657
-
F Sato SJ Meltzer 2006 CpG island hypermethylation in progression of esophageal and gastric cancer Cancer 106 483 493 16362978 10.1002/cncr.21657 1:CAS:528:DC%2BD28XhsFGiurg%3D (Pubitemid 43157610)
-
(2006)
Cancer
, vol.106
, Issue.3
, pp. 483-493
-
-
Sato, F.1
Meltzer, S.J.2
-
21
-
-
33746121227
-
RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer
-
DOI 10.1158/0008-5472.CAN-06-0369
-
QC Lau, et al. 2006 RUNX3 is frequently inactivated by dual mechanisms of protein mislocalization and promoter hypermethylation in breast cancer Cancer Res 66 6512 6520 16818622 10.1158/0008-5472.CAN-06-0369 1:CAS:528: DC%2BD28XmsVamtro%3D (Pubitemid 44085605)
-
(2006)
Cancer Research
, vol.66
, Issue.13
, pp. 6512-6520
-
-
Lau, Q.C.1
Raja, E.2
Salto-Tellez, M.3
Liu, Q.4
Ito, K.5
Inoue, M.6
Putti, T.C.7
Loh, M.8
Ko, T.K.9
Huang, C.10
Bhalla, K.N.11
Zhu, T.12
Ito, Y.13
Sukumar, S.14
-
22
-
-
4644363411
-
Promoter hypermethylation downregulates RUNX3 gene expression in colorectal cancer cell lines
-
DOI 10.1038/sj.onc.1207731
-
JL Ku, et al. 2004 Promoter hypermethylation downregulates RUNX3 gene expression in colorectal cancer cell lines Oncogene 23 6736 6742 15273736 10.1038/sj.onc.1207731 1:CAS:528:DC%2BD2cXntFGnurY%3D (Pubitemid 39280005)
-
(2004)
Oncogene
, vol.23
, Issue.40
, pp. 6736-6742
-
-
Ku, J.-L.1
Kang, S.-B.2
Shin, Y.-K.3
Kang, H.C.4
Hong, S.-H.5
Kim, I.-J.6
Shin, J.-H.7
Han, I.-O.8
Park, J.-G.9
-
23
-
-
1642474373
-
Promoter methylation status of tumor suppressor and tumor-related genes in neoplastic and non-neoplastic gastric epithelia
-
G Tamura 2004 Promoter methylation status of tumor suppressor and tumor-related genes in neoplastic and non-neoplastic gastric epithelia Histol Histopathol 19 221 228 14702190 1:CAS:528:DC%2BD2cXjtFyrtbo%3D (Pubitemid 38111266)
-
(2004)
Histology and Histopathology
, vol.19
, Issue.1
, pp. 221-228
-
-
Tamura, G.1
-
24
-
-
2942580970
-
Promoter hypermethylation of the Chfr gene in neoplastic and non-neoplastic gastric epithelia
-
DOI 10.1038/sj.bjc.6601849
-
T Honda, et al. 2004 Promoter hypermethylation of the Chfr gene in neoplastic and non-neoplastic gastric epithelia Br J Cancer 90 2013 2016 15138487 10.1038/sj.bjc.6601849 1:CAS:528:DC%2BD2cXjvVals7k%3D (Pubitemid 38746346)
-
(2004)
British Journal of Cancer
, vol.90
, Issue.10
, pp. 2013-2016
-
-
Honda, T.1
Tamura, G.2
Waki, T.3
Kawata, S.4
Nishizuka, S.5
Motoyama, T.6
-
25
-
-
0038527233
-
Promoter methylation status of DAP-kinase and RUNX3 genes in neoplastic and non-neoplastic gastric epithelia
-
DOI 10.1111/j.1349-7006.2003.tb01447.x
-
T Waki, et al. 2003 Promoter methylation status of DAP-kinase and RUNX3 genes in neoplastic and non-neoplastic gastric epithelia Cancer Sci 94 360 364 12824905 10.1111/j.1349-7006.2003.tb01447.x 1:CAS:528:DC%2BD3sXkslCns7w%3D (Pubitemid 36626369)
-
(2003)
Cancer Science
, vol.94
, Issue.4
, pp. 360-364
-
-
Waki, T.1
Tamura, G.2
Sato, M.3
Terashima, M.4
Nishizuka, S.5
Motoyama, T.6
-
26
-
-
21644464400
-
Promoter hypermethylation and silencing of CHFR mitotic stress checkpoint gene in human gastric cancers
-
15201973 1:CAS:528:DC%2BD2cXlvVeqsrs%3D
-
HC Kang, et al. 2004 Promoter hypermethylation and silencing of CHFR mitotic stress checkpoint gene in human gastric cancers Oncol Rep 12 129 133 15201973 1:CAS:528:DC%2BD2cXlvVeqsrs%3D
-
(2004)
Oncol Rep
, vol.12
, pp. 129-133
-
-
Kang, H.C.1
-
27
-
-
33745608461
-
Aberrant methylation of the CHFR gene in digestive tract cancer
-
Y Morioka, et al. 2006 Aberrant methylation of the CHFR gene in digestive tract cancer Anticancer Res 26 1791 1795 16827108 1:CAS:528: DC%2BD28XntV2nsb4%3D (Pubitemid 43989433)
-
(2006)
Anticancer Research
, vol.26
, Issue.3 A
, pp. 1791-1795
-
-
Morioka, Y.1
Hibi, K.2
Sakai, M.3
Koike, M.4
Fujiwara, M.5
Kodera, Y.6
Ito, K.7
Nakao, A.8
-
28
-
-
41349097718
-
Molecular biomarkers in urothelial bladder cancer
-
DOI 10.1111/j.1349-7006.2008.00735.x
-
WJ Kim SC Bae 2008 Molecular biomarkers in urothelial bladder cancer Cancer Sci 99 646 652 18377416 10.1111/j.1349-7006.2008.00735.x 1:CAS:528:DC%2BD1cXlsFygu70%3D (Pubitemid 351448065)
-
(2008)
Cancer Science
, vol.99
, Issue.4
, pp. 646-652
-
-
Kim, W.-J.1
Bae, S.-C.2
-
29
-
-
48649097939
-
Methylation of the RUNX3 promoter as a potential prognostic marker for bladder tumor
-
18639281 10.1016/j.juro.2008.05.002 1:CAS:528:DC%2BD1cXhtVKmsbbL
-
EJ Kim, et al. 2008 Methylation of the RUNX3 promoter as a potential prognostic marker for bladder tumor J Urol 180 1141 1145 18639281 10.1016/j.juro.2008.05.002 1:CAS:528:DC%2BD1cXhtVKmsbbL
-
(2008)
J Urol
, vol.180
, pp. 1141-1145
-
-
Kim, E.J.1
-
30
-
-
34447130265
-
Altered expression of the early mitotic checkpoint protein, CHFR, in breast cancers: Implications for tumor suppression
-
DOI 10.1158/0008-5472.CAN-06-4109
-
LM Privette ME Gonzalez L Ding CG Kleer EM Petty 2007 Altered expression of the early mitotic checkpoint protein, CHFR, in breast cancers: implications for tumor suppression Cancer Res 67 6064 6074 17596595 10.1158/0008-5472.CAN-06- 4109 1:CAS:528:DC%2BD2sXnsVyqsb8%3D (Pubitemid 47037485)
-
(2007)
Cancer Research
, vol.67
, Issue.13
, pp. 6064-6074
-
-
Privette, L.M.1
Gonzalez, M.E.2
Ding, L.3
Kleer, C.G.4
Petty, E.M.5
|