The social honey bee in biomedical research: Realities and expectations

Drug Discovery Today: Disease Models

Volumn 12, Issue , 2014, Pages 7-13

  Maleszka, Ryszard ^a  

^a AUSTRALIAN NATIONAL UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ROYAL JELLY;

ARTICLE; BEHAVIOR CHANGE; BRAIN FUNCTION; DNA METHYLATION; EPIGENETICS; GENE SEQUENCE; HONEYBEE; INVERTEBRATE MODEL; MEDICAL RESEARCH; NONHUMAN;

EID: 85027937004     PISSN: None     EISSN: 17406757     Source Type: Journal    
DOI: 10.1016/j.ddmod.2014.06.001     Document Type: Review

References (52)

1. H.S. Warren Mouse models to study sepsis syndrome in humans J Leukocyte Biol 86 2009 199 201
2. D. Van Dam, and P.P. De Deyn Animal models in the drug discovery pipeline for Alzheimer's disease Br J Pharmacol 164 2011 1285 1300
3. M.G. Smith, and M. Snyder Yeast as a model for human disease Curr Protoc Hum Genet 2006 Chapter 15:Unit 15.6
4. E.A. Cox-Paulson, T.M. Grana, M.A. Harris, and J.M. Batzli Studying human disease genes in Caenorhabditis elegans: a molecular genetics laboratory project CBE Life Sci Educ 11 2012 165 179
5. U.B. Pandey, and C.D. Nichols Human disease models in Drosophila melanogaster and the role of the fly in therapeutic drug discovery Pharmacol Rev 63 2011 411 436
6. C. Haass, and P. Kahle Neurodegenrative diseases: Parkinson's pathology in a fly Nature 404 2000 341 343
7. K. Howard The bioinformatics gold rush Scientific Am 283 2000 46 51
8. V. Setola, and B.L. Roth Why mice are neither miniature humans nor small rats: a cautionary tale involving 5-hydroxytryptamine-6 serotonin receptor species variants Mol Pharmacol 64 2003 1277 1278
9. J. Seok, H.S. Warren, A.G. Cuenca, M.N. Mindrinos, H.V. Baker, W. Xu, and et al. Genomic responses in mouse models poorly mimic human inflammatory diseases Proc Natl Acad Sci USA 110 2013 3507 3512
10. X. Wen, S. Fuhrman, G.S. Michaels, D.B. Carr, S. Smith, J.L. Barker, and et al. Large-scale temporal gene expression mapping of central nervous system development Proc Natl Acad Sci USA 95 1998 334 339
11. G.L.G. Miklos, and R. Maleszka Microarray reality checks in the context of a complex disease Nat Biotechnol 22 2004 615 621
12. R. Maleszka, P. Mason, and A. Barron Epigenomics and the concept of degeneracy in biology Brief Funct Genomics 13 2013 191 202
13. A. Ajibola, J.P. Chamunorwa, and K.H. Erlwanger Nutraceutical values of natural honey and its contribution to human health and wealth Nutr Metab (Lond) 9 2012 61
14. P.H. Kwakman, and S.A. Zaat Antibacterial components of honey IUBMB Life 64 2011 48 55
15. R. Maleszka Elucidating the path from genotype to behaviour in honey bees: insights from epigenomics D. Eisenhardt, G. Galizia, M. Giurfa, Honeybee neurobiology and behavior: a tribute to Randolf Menzel 2012 Springer Publisher 373 386
16. R. Menzel The honeybee as a model for understanding the basis of cognition Nat Rev Neurosci 13 2012 758 768
17. G. Scangos Drug discovery in the postgenomic era Nat Biotech 15 1997 1220 1221
18. S.K. Chanda, and J.S. Caldwell Fulfilling the promise: drug discovery in the post-genomic era Drug Discov Today 8 2003 168 174
19. Honey Bee Genome Consortium Insights into social insects from the genome of the honey bee Apis mellifera Nature 443 2006 931 949
20. S. Foret, R. Kucharski, Y. Pittelkow, G.A. Lockett, and R. Maleszka Epigenetic regulation of the honey bee transcriptome: unravelling the nature of methylated genes BMC Genomics 10 2009 472
21. F. Lyko, S. Foret, R. Kucharski, S. Wolf, C. Falckenhayn, and R. Maleszka The honey bee epigenomes: differential methylation of brain DNA in queens and workers PloS Biol 8 2010 e1000506
22. F. Lyko, and R. Maleszka Insects as innovative models for functional studies on DNA methylation Trends Genet 27 2011 127 131
23. S. Foret, R. Kucharski, M. Pellegrini, S. Feng, S.E. Jacobsen, G.E. Robinson, and et al. DNA methylation dynamics, metabolic fluxes, gene splicing and alternative phenotypes in honey bees Proc Natl Acad Sci USA 109 2012 4968 4973
24. G.L.G. Miklos, and R. Maleszka Epigenomic communication systems in humans and honey bees: from molecules to behaviour Hormones Behav 59 2011 399 406
25. M.J. Dickman, R. Kucharski, R. Maleszka, and P. Hurd Extensive histone post-translational modification in honey bees Insect Biochem Mol Biol 43 2013 125 137
26. A.R. Isles, and L.S. Wilkinson Epigenetics: what is it and why is it important to mental disease? Br Med Bull 85 2008 35 45
27. G.A. Lockett, F. Wilkes, and R. Maleszka Brain plasticity, memory and neurological disorders; an epigenetic perspective NeuroReport 21 2010 909 913
28. A. Portela, and M. Esteller Epigenetic modifications and human disease Nat Biotechnol 28 2010 1057 1068
29. R. Maleszka Epigenetic integration of environmental and genomic signals in honey bees: the critical interplay of nutritional, brain and reproductive networks Epigenetics 3 2008 188 192
30. G.A. Lockett, P. Helliwell, and R. Maleszka Involvement of DNA methylation in memory processing in the honey bee NeuroReport 21 2010 812 816
31. G.A. Lockett, R. Kucharski, and R. Maleszka DNA methylation changes elicited by social stimuli in the brains of worker honey bees Genes Brain Behav 11 2012 235 242
32. D.R. Donohoe, and S.J. Bultman Metaboloepigenetics: interrelationships between energy metabolism and epigenetic control of gene expression J Cell Physiol 227 2012 3169 3177
33. M. Wojciechowski, D. Rafalski, R. Kucharski, K. Misztal, J. Maleszka, M. Bochtler, and et al. Insights into DNA hydroxylmethylation in the honeybee from in-depth analyses of TET dioxygenase Open Biol 4 2014 140110
34. J.L. Dimarcq, and S. Dawe Exploiting insects in the search for new drugs Innovations Pharmacol Technol September 2003 29 34
35. X. Zhang, R. Xue, G. Cao, Z. Pan, X. Zheng, and C. Gong Silkworms can be used as an animal model to screen and evaluate gouty therapeutic drugs J Insect Sci 12 2012 4
36. A.B. Barron, J. Maleszka, R.K. Vander Meer, G.E. Robinson, and R. Maleszka Comparing injection, feeding and topical application methods for treatment of honey bees with octopamine J Insect Physiol 53 2007 187 194
37. A.B. Barron, R. Maleszka, P. Helliwell, and G.E. Robinson Effects of cocaine on honey bee dance behaviour J Exp Biol 211 2009 163 168
38. R. Kucharski, and R. Maleszka Evaluation of differential gene expression during behavioral development in the honeybee using microarrays and northern blots Genome Biol 3 2002 7.1 7.9
39. R. Kucharski, and R. Maleszka Microarray and rtPCR analyses of gene expression in the honey bee brain following caffeine treatment J Mol Neurosci 27 2005 269 276
40. G.A. Lockett, F. Wilkes, P. Helliwell, and R. Maleszka Contrasting effects of histone deacetylase inhibitors on reward and aversive olfactory memories in the honey bee Insects 5 2014 377 398
41. H. Rembold Biologically active substances in royal jelly Vitam Horm 23 1965 359 382
42. B. Hallberg, and R.H. Palmer Crizotinib - latest champion in the cancer wars? N Engl J Med 363 2010 1760 1762
43. G.L. Gravina, C. Festuccia, F. Marampon, V.M. Popov, R.G. Pestell, B.M. Zani, and et al. Biological rationale for the use of DNA methyltransferase inhibitors as new strategy for modulation of tumor response to chemotherapy and radiation Mol Cancer 9 2010 305
44. S. Subramanian, S.E. Bates, J.J. Wright, I. Espinoza-Delgado, and R.L. Piekarz Clinical toxicities of histone deacetylase inhibitors Pharmaceuticals 3 2010 2751 2767
45. R. Maleszka, H.G. de Couet, and G.L. Miklos Data transferability from model organisms to human beings: insights from the functional genomics of the flightless region of Drosophila Proc Natl Acad Sci USA 95 1998 3731 3736
46. R. Kucharski, J. Maleszka, S. Foret, and R. Maleszka Nutritional control of reproductive status in honey bees via DNA methylation Science 319 2008 1827 1830
47. A. Spannhoff, Y.K. Kim, N.J. Raynal, V. Vibyan, M.B. Su, Y.Y. Zhou, and et al. Histone deacetylase inhibitor activity in royal jelly might facilitate caste switching in bees EMBO Rep 12 2011 238 243
48. H.L. Kang, S. Benzer, and K.T. Min Life extension in Drosophila by feeding a drug Proc Natl Acad Sci USA 99 2002 838 843
49. M. Kamakura Royalactin induces queen differentiation in honeybees Nature 473 2011 478 483
50. G.F. Townsend, J.F. Morgan, S. Tolnai, B. Hazlett, H.J. Morton, and R.W. Shuel Studies on the in vitro antitumor activity of fatty acids. I. 10-Hydroxy-2-decenoic acid from royal jelly Cancer Res 20 1960 504 510
51. N. Hattori, H. Nomoto, H. Fukumitsu, S. Mishima, and S. Furukawa Royal jelly and its unique fatty acid, 10-hydroxy-trans-2-decenoic acid, promote neurogenesis by neural stem/progenitor cells in vitro Biomed Res 28 2007 261 266
52. H. Izuta, Y. Chikaraishi, M. Shimazawa, S. Mishima, and H. Hara 10-Hydroxy-2-decenoic acid, a major fatty acid from royal jelly, inhibits VEGF-induced angiogenesis in human umbilical vein endothelial cells Evid Based Complement Alternat Med 6 2009 489 494