Probiotics versus antibiotic decontamination of the digestive tract: Infection and mortality

Intensive Care Medicine

Volumn 37, Issue 1, 2011, Pages 110-117

  Oudhuis, Guy J ^a   Bergmans, Dennis C ^b   Dormans, Tom ^c   Zwaveling, Jan Harm ^b   Kessels, Alfons ^b   Prins, Martin H ^b   Stobberingh, Ellen E ^a   Verbon, Annelies ^a  

^a MAASTRICHT UNIVERSITY   (Netherlands)

^b MAASTRICHT UNIVERSITY MEDICAL CENTER   (Netherlands)

^c Sittard Geleen Heerlen   (Netherlands)

Author keywords

Antibiotics; Critical care; Lactobacillus; Nosocomial infections; Survival

Indexed keywords

AMOXICILLIN; AMOXICILLIN PLUS CLAVULANIC ACID; AMPHOTERICIN B; ANTIBIOTIC AGENT; CARBAPENEM DERIVATIVE; CEFAZOLIN; CEFOTAXIME; CEFTAZIDIME; CEFTRIAXONE; CEFUROXIME; CLINDAMYCIN; COLISTIN; COTRIMOXAZOLE; FLUCLOXACILLIN; GENTAMICIN; MACROLIDE; PIPERACILLIN; PIPERACILLIN PLUS TAZOBACTAM; PROBIOTIC AGENT; QUINOLINE DERIVED ANTIINFECTIVE AGENT; VANCOMYCIN;

ADULT; AGED; ANTIBIOTIC RESISTANCE; ARTICLE; ARTIFICIAL VENTILATION; BACTERIUM CULTURE; BACTERIUM ISOLATION; CONTROLLED STUDY; CRITICALLY ILL PATIENT; ENTEROBACTERIACEAE; FEMALE; GASTROINTESTINAL INFECTION; GRAM POSITIVE COCCI; HUMAN; INFECTION PREVENTION; INFECTION RATE; INTENSIVE CARE; LACTOBACILLUS PLANTARUM; MAJOR CLINICAL STUDY; MALE; MORTALITY; PANCREATITIS; PSEUDOMONAS AERUGINOSA;

EID: 85027934185     PISSN: 03424642     EISSN: 14321238     Source Type: Journal    
DOI: 10.1007/s00134-010-2002-6     Document Type: Article

References (35)

1. D Inan R Saba F Gunseren G Ongut O Turhan AN Yalcin L Mamikoglu 2005 Daily antibiotic cost of nosocomial infections in a Turkish university hospital BMC Infect Dis 5 5 10.1186/1471-2334-5-5 15679899 (Pubitemid 41363820)
2. JL Vincent 2003 Nosocomial infections in adult intensive-care units Lancet 361 2068 2077 10.1016/S0140-6736(03)13644-6 12814731 (Pubitemid 36695053)
3. DR Park 2005 The microbiology of ventilator-associated pneumonia Respir Care 50 742 763 15913466 (discussion 763-745)
4. CP Stoutenbeek HK van Saene DR Miranda DF Zandstra 1984 The effect of selective decontamination of the digestive tract on colonisation and infection rate in multiple trauma patients Intensive Care Med 10 185 192 1:STN:280:DyaL2c3ptVamug%3D%3D 10.1007/BF00259435 6470306
5. E De Jonge MJ Schultz L Spanjaard PM Bossuyt MB Vroom J Dankert J Kesecioglu 2003 Effects of selective decontamination of digestive tract on mortality and acquisition of resistant bacteria in intensive care: a randomised controlled trial Lancet 362 1011 1016 10.1016/S0140-6736(03)14409-1 14522530 (Pubitemid 37186877)
6. MA De La Cal E Cerda P Garcia-Hierro HK van Saene D Gomez-Santos E Negro JA Lorente 2005 Survival benefit in critically ill burned patients receiving selective decontamination of the digestive tract: a randomized, placebo-controlled, double-blind trial Ann Surg 241 424 430 10.1097/01.sla. 0000154148.58154.d5 (Pubitemid 40299718)
7. AM De Smet JA Kluytmans BS Cooper EM Mascini RF Benus TS van der Werf JG van der Hoeven P Pickkers D Bogaers-Hofman NJ van der Meer AT Bernards EJ Kuijper JC Joore MA Leverstein-van Hall AJ Bindels AR Jansz RM Wesselink BM de Jongh PJ Dennesen GJ van Asselt LF te Velde IH Frenay K Kaasjager FH Bosch M van Iterson SF Thijsen GH Kluge W Pauw JW de Vries JA Kaan JP Arends LP Aarts PD Sturm HI Harinck A Voss EV Uijtendaal HE Blok ES Thieme Groen ME Pouw CJ Kalkman MJ Bonten 2009 Decontamination of the digestive tract and oropharynx in ICU patients N Engl J Med 360 20 31 10.1056/NEJMoa0800394 19118302
8. Liberati A, D'Amico R, Pifferi S, Torri V, Brazzi L, Parmelli E (2009) Antibiotic prophylaxis to reduce respiratory tract infections and mortality in adults receiving intensive care. Cochrane Database Syst Rev CD000022
9. EA Oostdijk AM de Smet HE Blok ES Thieme Groen GJ van Asselt RF Benus SA Bernards IH Frenay AR Jansz BM de Jongh JA Kaan MA Leverstein-van Hall EM Mascini W Pauw PD Sturm SF Thijsen JA Kluytmans MJ Bonten 2010 Ecological effects of selective decontamination on resistant Gram-negative bacterial colonization Am J Respir Crit Care Med 181 452 457 10.1164/rccm.200908-1210OC 19965807
10. W Isakow LE Morrow MH Kollef 2007 Probiotics for preventing and treating nosocomial infections: review of current evidence and recommendations Chest 132 286 294 10.1378/chest.06-2156 17625089 (Pubitemid 47068233)
11. K Madsen 2008 Probiotics in critically ill patients J Clin Gastroenterol 42 Suppl 3 Pt 1 S116 S118 10.1097/MCG.0b013e31817283cb 18806700
12. N Rayes S Hansen D Seehofer AR Muller S Serke S Bengmark P Neuhaus 2002 Early enteral supply of fiber and lactobacilli versus conventional nutrition: a controlled trial in patients with major abdominal surgery Nutrition 18 609 615 10.1016/S0899-9007(02)00811-0 12093440 (Pubitemid 34687100)
13. A Olah T Belagyi A Issekutz ME Gamal S Bengmark 2002 Randomized clinical trial of specific Lactobacillus and fibre supplement to early enteral nutrition in patients with acute pancreatitis Br J Surg 89 1103 1107 1:STN:280: DC%2BD38vjsVWjuw%3D%3D 10.1046/j.1365-2168.2002.02189.x 12190674 (Pubitemid 34989215)
14. N Rayes D Seehofer S Hansen K Boucsein AR Muller S Serke S Bengmark P Neuhaus 2002 Early enteral supply of Lactobacillus and fiber versus selective bowel decontamination: a controlled trial in liver transplant recipients Transplantation 74 123 127 10.1097/00007890-200207150-00021 12134110
15. MG Besselink HC van Santvoort E Buskens MA Boermeester H van Goor HM Timmerman VB Nieuwenhuijs TL Bollen B van Ramshorst BJ Witteman C Rosman RJ Ploeg MA Brink AF Schaapherder CH Dejong PJ Wahab CJ van Laarhoven E van der Harst CH van Eijck MA Cuesta LM Akkermans HG Gooszen 2008 Probiotic prophylaxis in predicted severe acute pancreatitis: a randomised, double-blind, placebo-controlled trial Lancet 371 651 659 10.1016/S0140-6736(08)60207-X 18279948
16. JS Garner WR Jarvis TG Emori TC Horan JM Hughes 1988 CDC definitions for nosocomial infections Am J Infect Control 16 128 140 1:STN:280: DyaL1czgvVSnug%3D%3D 10.1016/0196-6553(88)90053-3 2841893
17. CF Linssen JA Jacobs JS Schouten WN van Mook G Ramsay M Drent 2008 Influence of antibiotic therapy on the cytological diagnosis of ventilator-associated pneumonia Intensive Care Med 34 865 872 10.1007/s00134-008-1015-x 18251009 (Pubitemid 351571193)
18. Clinical Laboratory Standards Institute (2006) Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically-seventh edition: approved standard M7-A7. CLSI, Wayne, PA
19. WHO Collaborating Centre for Drug Statistics Methodology (2006) Anatomical therapeutic chemical (ATC) classification index with defined daily doses (DDDs). WHO Collaborating Centre, Oslo, Norway
20. PM Filius TB Liem PD van der Linden R Janknegt S Natsch AG Vulto HA Verbrugh 2005 An additional measure for quantifying antibiotic use in hospitals J Antimicrob Chemother 55 805 808 1:CAS:528:DC%2BD2MXjvFymu74%3D 10.1093/jac/dki093 15814603 (Pubitemid 40691868)
21. MJ Bonten BJ Kullberg R van Dalen AR Girbes IM Hoepelman W Hustinx JW van der Meer P Speelman EE Stobberingh HA Verbrugh J Verhoef JH Zwaveling Consultants of the Dutch Working Group on Antibiotic Policy 2000 Selective digestive decontamination in patients in intensive care J Antimicrob Chemother 46 351 362 1:CAS:528:DC%2BD3cXmvV2ktrY%3D 10.1093/jac/46.3.351 10980160
22. S Puffer D Torgerson J Watson 2003 Evidence for risk of bias in cluster randomised trials: review of recent trials published in three general medical journals BMJ 327 785 789 10.1136/bmj.327.7418.785 14525877
23. MK Campbell DR Elbourne DG Altman 2004 CONSORT statement: extension to cluster randomised trials BMJ 328 702 708 10.1136/bmj.328.7441.702 15031246
24. WA Knaus EA Draper DP Wagner JE Zimmerman 1985 APACHE II: a severity of disease classification system Crit Care Med 13 818 829 1:STN:280: DyaL2M3otlyqtQ%3D%3D 10.1097/00003246-198510000-00009 3928249
25. M Garrouste-Orgeas G Troche E Azoulay A Caubel A de Lassence C Cheval L Montesino M Thuong F Vincent Y Cohen JF Timsit 2004 Body mass index. An additional prognostic factor in ICU patients Intensive Care Med 30 437 443 10.1007/s00134-003-2095-2 14767583 (Pubitemid 38375618)
26. PK Jain CE McNaught AD Anderson J MacFie CJ Mitchell 2004 Influence of synbiotic containing Lactobacillus acidophilus La5, Bifidobacterium lactis Bb 12, Streptococcus thermophilus, Lactobacillus bulgaricus and oligofructose on gut barrier function and sepsis in critically ill patients: a randomised controlled trial Clin Nutr 23 467 475 10.1016/j.clnu.2003.12.002 15297081 (Pubitemid 39107024)
27. K Kotzampassi EJ Giamarellos-Bourboulis A Voudouris P Kazamias E Eleftheriadis 2006 Benefits of a synbiotic formula (Synbiotic 2000Forte) in critically ill trauma patients: early results of a randomized controlled trial World J Surg 30 1848 1855 10.1007/s00268-005-0653-1 16983476 (Pubitemid 44454998)
28. WA Krueger FP Lenhart G Neeser G Ruckdeschel H Schreckhase HJ Eissner H Forst J Eckart K Peter KE Unertl 2002 Influence of combined intravenous and topical antibiotic prophylaxis on the incidence of infections, organ dysfunctions, and mortality in critically ill surgical patients: a prospective, stratified, randomized, double-blind, placebo-controlled clinical trial Am J Respir Crit Care Med 166 1029 1037 10.1164/rccm.2105141 12379544 (Pubitemid 35178699)
29. A Heininger E Meyer F Schwab M Marschal K Unertl WA Krueger 2006 Effects of long-term routine use of selective digestive decontamination on antimicrobial resistance Intensive Care Med 32 1569 1576 10.1007/s00134-006-0304-5 16896852 (Pubitemid 44484347)
30. SWAB (2009) NethMap 2009-consumption of antimicrobial agents and antimicrobial resistance among medically important bacteria in The Netherlands. http://www.swab.nl/swab/cms3.nsf/viewdoc/2E7389A33973953BC12575D1002A01C3. Accessed 03 March 2010
31. HM Timmerman LE Niers BU Ridwan CJ Koning L Mulder LM Akkermans FM Rombouts GT Rijkers 2007 Design of a multispecies probiotic mixture to prevent infectious complications in critically ill patients Clin Nutr 26 450 459 10.1016/j.clnu.2007.04.008 17544549 (Pubitemid 47091487)
32. S Bengmark 2004 Synbiotics to strengthen gut barrier function and reduce morbidity in critically ill patients Clin Nutr 23 441 445 10.1016/j.clnu.2004. 01.005 15297078 (Pubitemid 39107021)
33. M Melis A Fichera MK Ferguson 2006 Bowel necrosis associated with early jejunal tube feeding: a complication of postoperative enteral nutrition Arch Surg 141 701 704 10.1001/archsurg.141.7.701 16847244 (Pubitemid 44079838)
34. MJ Bonten J Kluytmans AM De Smet M Bootsma A Hoes 2003 Selective decontamination of digestive tract in intensive care Lancet 362 2118 2119 10.1016/S0140-6736(03)15120-3 14697824 (author reply 2119-2120)
35. HA Verbrugh 2003 Selective decontamination of digestive tract in intensive care Lancet 362 2117 2118 10.1016/S0140-6736(03)15117-3 14697820 (Pubitemid 38032772)