Activating KIR/HLA complexes in classic Kaposi's Sarcoma

Infectious Agents and Cancer

Volumn 7, Issue 1, 2012, Pages

  Guerini, Franca R ^a   Mancuso, Roberta ^a   Agostini, Simone ^a,b   Agliardi, Cristina ^a   Zanzottera, Milena ^a   Hernis, Ambra ^a   Tourlaki, Athanasia ^c   Calvo, Maria G ^a   Bellinvia, Monica ^c   Brambilla, Lucia ^c   Clerici, Mario ^a,b  

^a IRCCS FONDAZIONE DON CARLO GNOCCHI   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

^c FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

Author keywords

HLA; Human Herpesvirus 8; Kaposi's Sarcoma; KIR; KSHV; NK cells

Indexed keywords

HLA ANTIGEN CLASS 2; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR; KILLER CELL IMMUNOGLOBULIN LIKE RECEPTOR 3DS1; KIR2DS1 PROTEIN; UNCLASSIFIED DRUG;

AGE DISTRIBUTION; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENETIC ASSOCIATION; GENOTYPE; HLA SYSTEM; HUMAN; HUMAN HERPESVIRUS 8; HUMAN HERPESVIRUS 8 INFECTION; KAPOSI SARCOMA; MALE; MOLECULAR GENETICS; NATURAL KILLER CELL; PRIORITY JOURNAL; SEROLOGY; SEX RATIO; VIRUS INFECTION;

EID: 85027918562     PISSN: None     EISSN: 17509378     Source Type: Journal    
DOI: 10.1186/1750-9378-7-922469025     Document Type: Article

References (18)

1. Iscovich J, Boffetta P, Franceschi S, Azizi E, Sarid R: Classic kaposi sarcoma: epidemiology and risk factors. Cancer 2000, 88:500-517. (Pubitemid 30056922)
2. Vilches C, Parham P: KIR: diverse, rapidly evolving receptors of innate and adaptive immunity. Annu Rev Immunol 2002, 20:217-251. (Pubitemid 34293425)
3. Caligiuri MA: Human natural killer cells. Blood 2008, 112:461-469.
4. Lanier LL: Up on the tightrope: natural killer cell activation and inhibition. Nat Immunol 2008, 9:495-502.
5. Cerwenka A, Lanier LL: Natural killer cells, viruses and cancer. Nat Rev Immunol 2001, 1:41-49. (Pubitemid 33741974)
6. Renne R, Zhong W, Herndier B, McGrath M, Abbey N, Kedes D, Ganem D: Lytic growth of Kaposi's sarcoma-associated herpesvirus (human herpesvirus 8) in culture. Nat Med 1996, 2:342-346. (Pubitemid 26080656)
7. Mancuso R, Biffi R, Valli M, Bellinvia M, Tourlaki A, Ferrucci S, Brambilla L, Del Bue S, Ferrante P, et al: HHV-8 A Subtype Is Associated With Rapidly Evolving Classic Kaposi's Sarcoma. J Med Virol 2008, 80:2153-2160.
8. Middleton D, Gonzelez F: The extensive polymorphism of KIR genes. Immunology 2010, 129:8-19.
9. Middleton D, Williams F, Halfpenny IA: KIR genes. Transpl Immunol 2005, 14:135-142. (Pubitemid 40848518)
10. Martin MP, Gao X, Lee JH, Nelson R, Detels JJ, Goedert S, Buchbinder K, Hoots D, Vlahov J, Trowsdale M, Wilson S, O'Brien J, Carrington M: Epistatic interaction between KIR3DS1 and HLA-B delays the progression to AIDS. Nat Genet 2002, 31:429-434. (Pubitemid 35154456)
11. Kulkarni S, Martin MP, Carrington M: The Yin and Yang of HLA and KIR in human disease. Semin Immunol 2008, 20:343-352.
12. Carrington M, Wang S, Martin MP, Gao X, Schiffman M, Cheng J, Herrero R, Rodriguez AC, Kurman R, Mortel R, Schwartz P, Glass A, Hildesheim A: Hierarchy of resistance to cervical neoplasia mediated by combinations of killer immunoglobulin-like receptor and human leukocyte antigen loci. J Exp Med 2005, 201:1069-1075. (Pubitemid 40524675)
13. Martin MP, Borecki IB, Zhang Z, Nguyen L, Ma D, Gao X, Qi Y, Carrington M, Rader JS: HLA-Cw group 1 ligands for KIR increase susceptibility to invasive cervical cancer. Immunogenetics 2010, 62(11-12):761-765.
14. Butsch Kovacic M, Martin M, Gao X, Fuksenko T, Chen CJ, Cheng YJ, Chen JY, Apple R, Hildesheim A, Carrington M: Variation of the killer cell immunoglobulin-like receptors and HLA-C genes in nasopharyngeal carcinoma. Cancer Epidemiol Biomarkers Prev 2005, 14(11 Pt 1):2673-2677. (Pubitemid 41752733)
15. López-Vázquez A, Rodrigo L, Martínez-Borra J, Pérez R, Rodríguez M, Fdez-Morera JL, Fuentes D, Rodríguez-Rodero S, Gonzáez S, López-Larrea C: Protective effect of the HLA-Bw4I80 epitope and the killer cell immunoglobulin-like receptor 3DS1 gene against the development ofhepatocellular carcinoma in patients with hepatitis C virus infection. J Infect Dis 2005, 1;192(1):162-5.
16. Pantanowitz L, Moses AV, Dezube BJ: The inflammatory component of Kaposi sarcoma. Exp Mol Pathol 2009, 87:163-165, Review.
17. Balkwill F, Charles KA, Mantovani A: Smoldering and polarized inflammation in the initiation and promotion of malignant disease. Cancer Cell 2005, 7:211-217. (Pubitemid 40568680)
18. Carrington M, Martin MP: The impact of variation at the KIR gene cluster on human disease. In Current topics in microbiology and immunology: activating and inhibitory NK cell receptors. Edited by: Vivier E, Colonna M. Heidelberg (Germany): Springer; 2005:.