메뉴 건너뛰기




Volumn 82, Issue 10, 2017, Pages 702-708

No Evidence That Schizophrenia Candidate Genes Are More Associated With Schizophrenia Than Noncandidate Genes

Author keywords

Candidate genes; Complex traits; Gene set analysis; Genome wide association study; GWAS; Schizophrenia; Single nucleotide polymorphism; SNP

Indexed keywords

APOLIPOPROTEIN E; BRAIN DERIVED NEUROTROPHIC FACTOR; BUNGAROTOXIN RECEPTOR; CATECHOL METHYLTRANSFERASE; DISRUPTED IN SCHIZOPHRENIA 1 PROTEIN; DOPAMINE 2 RECEPTOR; DOPAMINE 3 RECEPTOR; DOPAMINE 4 RECEPTOR; DOPAMINE TRANSPORTER; DYSBINDIN; NOTCH4 RECEPTOR; RGS4 PROTEIN; SEROTONIN TRANSPORTER; TUMOR NECROSIS FACTOR;

EID: 85027437069     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2017.06.033     Document Type: Article
Times cited : (101)

References (37)
  • 2
    • 46249104490 scopus 로고    scopus 로고
    • Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: The SzGene database
    • Allen, N.C., Bagade, S., McQueen, M.B., Ioannidis, J.P., Kavvoura, F.K., Khoury, M.J., et al. Systematic meta-analyses and field synopsis of genetic association studies in schizophrenia: The SzGene database. Nat Genet 40 (2008), 827–834.
    • (2008) Nat Genet , vol.40 , pp. 827-834
    • Allen, N.C.1    Bagade, S.2    McQueen, M.B.3    Ioannidis, J.P.4    Kavvoura, F.K.5    Khoury, M.J.6
  • 3
    • 66149185456 scopus 로고    scopus 로고
    • Genomewide association studies: History, rationale, and prospects for psychiatric disorders
    • Cichon, S., Craddock, N., Daly, M., Faraone, S.V., Gejman, P.V., Kelsoe, J., et al. Genomewide association studies: History, rationale, and prospects for psychiatric disorders. Am J Psychiatry 166 (2009), 540–556.
    • (2009) Am J Psychiatry , vol.166 , pp. 540-556
    • Cichon, S.1    Craddock, N.2    Daly, M.3    Faraone, S.V.4    Gejman, P.V.5    Kelsoe, J.6
  • 4
    • 0034426026 scopus 로고    scopus 로고
    • The NOTCH4 locus is associated with susceptibility to schizophrenia
    • Wei, J., Hemmings, G.P., The NOTCH4 locus is associated with susceptibility to schizophrenia. Nat Genet 25 (2000), 376–377.
    • (2000) Nat Genet , vol.25 , pp. 376-377
    • Wei, J.1    Hemmings, G.P.2
  • 6
    • 33751112508 scopus 로고    scopus 로고
    • Analysis of high-resolution HapMap of DTNBP1 (Dysbindin) suggests no consistency between reported common variant associations and schizophrenia
    • Mutsuddi, M., Morris, D.W., Waggoner, S.G., Daly, M.J., Scolnick, E.M., Sklar, P., Analysis of high-resolution HapMap of DTNBP1 (Dysbindin) suggests no consistency between reported common variant associations and schizophrenia. Am J Hum Genet 79 (2006), 903–909.
    • (2006) Am J Hum Genet , vol.79 , pp. 903-909
    • Mutsuddi, M.1    Morris, D.W.2    Waggoner, S.G.3    Daly, M.J.4    Scolnick, E.M.5    Sklar, P.6
  • 8
    • 84904804929 scopus 로고    scopus 로고
    • Biological insights from 108 schizophrenia-associated genetic loci
    • Ripke, S., Neale, B.M., Corvin, A., Walters, J.T.R., Farh, K.-H., Holmans, P.A., et al. Biological insights from 108 schizophrenia-associated genetic loci. Nature 511 (2014), 421–427.
    • (2014) Nature , vol.511 , pp. 421-427
    • Ripke, S.1    Neale, B.M.2    Corvin, A.3    Walters, J.T.R.4    Farh, K.-H.5    Holmans, P.A.6
  • 9
    • 84856035474 scopus 로고    scopus 로고
    • Hypothesis-driven candidate genes for schizophrenia compared with genome-wide association results
    • Collins, A.L., Kim, Y., Sklar, P., O'Donovan, M.C., Sullivan, P.F., Hypothesis-driven candidate genes for schizophrenia compared with genome-wide association results. Psychol Med 42 (2012), 607–616.
    • (2012) Psychol Med , vol.42 , pp. 607-616
    • Collins, A.L.1    Kim, Y.2    Sklar, P.3    O'Donovan, M.C.4    Sullivan, P.F.5
  • 10
    • 68449086236 scopus 로고    scopus 로고
    • Common polygenic variation contributes to risk of schizophrenia and bipolar disorder
    • International Schizophrenia Consortium, Purcell, S.S.M., Wray, N.R.N., Stone, J.J.L., Visscher, P.M., O'Donovan, M.C., Sullivan, P.F., et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder. Nature 460 (2009), 748–752.
    • (2009) Nature , vol.460 , pp. 748-752
    • Purcell, S.S.M.1    Wray, N.R.N.2    Stone, J.J.L.3    Visscher, P.M.4    O'Donovan, M.C.5    Sullivan, P.F.6
  • 11
    • 68449096727 scopus 로고    scopus 로고
    • Common variants on chromosome 6p22.1 are associated with schizophrenia
    • Shi, J., Levinson, D.F., Duan, J., Sanders, A.R., Zheng, Y., Pe'er, I., et al. Common variants on chromosome 6p22.1 are associated with schizophrenia. Nature 460 (2009), 753–757.
    • (2009) Nature , vol.460 , pp. 753-757
    • Shi, J.1    Levinson, D.F.2    Duan, J.3    Sanders, A.R.4    Zheng, Y.5    Pe'er, I.6
  • 13
    • 0037312921 scopus 로고    scopus 로고
    • Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease
    • Lohmueller, K.E., Pearce, C.L., Pike, M., Lander, E.S., Hirschhorn, J.N., Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease. Nat Genet 33 (2003), 177–182.
    • (2003) Nat Genet , vol.33 , pp. 177-182
    • Lohmueller, K.E.1    Pearce, C.L.2    Pike, M.3    Lander, E.S.4    Hirschhorn, J.N.5
  • 15
    • 33846642542 scopus 로고    scopus 로고
    • The genetics of schizophrenia
    • Sullivan, P.F., The genetics of schizophrenia. PLoS Med, 2, 2005, e212.
    • (2005) PLoS Med , vol.2 , pp. e212
    • Sullivan, P.F.1
  • 16
    • 12344327212 scopus 로고    scopus 로고
    • Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence
    • Harrison, P.J., Weinberger, D.R., Schizophrenia genes, gene expression, and neuropathology: On the matter of their convergence. Mol Psychiatry 10 (2005), 40–68.
    • (2005) Mol Psychiatry , vol.10 , pp. 40-68
    • Harrison, P.J.1    Weinberger, D.R.2
  • 17
    • 85028296791 scopus 로고    scopus 로고
    • LD Hub: A centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis
    • Zheng, J., Erzurumluoglu, A.M., Elsworth, B.L., Kemp, J.P., Howe, L., Haycock, P.C., et al. LD Hub: A centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis. Bioinformatics 33 (2017), 272–279.
    • (2017) Bioinformatics , vol.33 , pp. 272-279
    • Zheng, J.1    Erzurumluoglu, A.M.2    Elsworth, B.L.3    Kemp, J.P.4    Howe, L.5    Haycock, P.C.6
  • 19
    • 76049098158 scopus 로고    scopus 로고
    • Functional gene group analysis reveals a role of synaptic heterotrimeric G proteins in cognitive ability
    • Ruano, D., Abecasis, G.R., Glaser, B., Lips, E.S., Cornelisse, L.N., de Jong, A.P.H., et al. Functional gene group analysis reveals a role of synaptic heterotrimeric G proteins in cognitive ability. Am J Hum Genet 86 (2010), 113–125.
    • (2010) Am J Hum Genet , vol.86 , pp. 113-125
    • Ruano, D.1    Abecasis, G.R.2    Glaser, B.3    Lips, E.S.4    Cornelisse, L.N.5    de Jong, A.P.H.6
  • 20
    • 84866736529 scopus 로고    scopus 로고
    • Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia
    • Lips, E.S., Cornelisse, L.N., Toonen, R.F., Min, J.L., Hultman, C.M., Holmans, P.A., et al. Functional gene group analysis identifies synaptic gene groups as risk factor for schizophrenia. Mol Psychiatry 17 (2012), 996–1006.
    • (2012) Mol Psychiatry , vol.17 , pp. 996-1006
    • Lips, E.S.1    Cornelisse, L.N.2    Toonen, R.F.3    Min, J.L.4    Hultman, C.M.5    Holmans, P.A.6
  • 21
    • 84975795680 scopus 로고    scopus 로고
    • An integrated map of genetic variation from 1,092 human genomes
    • Genomes Project Consortium, Abecasis, G.R., Auton, A., Brooks, L.D., DePristo, M.A., Durbin, R.M., et al. An integrated map of genetic variation from 1,092 human genomes. Nature 491 (2012), 56–65.
    • (2012) Nature , vol.491 , pp. 56-65
    • Abecasis, G.R.1    Auton, A.2    Brooks, L.D.3    DePristo, M.A.4    Durbin, R.M.5
  • 25
    • 84958074030 scopus 로고    scopus 로고
    • Schizophrenia risk from complex variation of complement component 4
    • Sekar, A., Bialas, A.R., de Rivera, H., Davis, A., Hammond, T.R., Kamitaki, N., et al. Schizophrenia risk from complex variation of complement component 4. Nature 530 (2016), 177–183.
    • (2016) Nature , vol.530 , pp. 177-183
    • Sekar, A.1    Bialas, A.R.2    de Rivera, H.3    Davis, A.4    Hammond, T.R.5    Kamitaki, N.6
  • 26
    • 84929001104 scopus 로고    scopus 로고
    • The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans
    • Ardlie, K.G., Deluca, D.S., Segrè A.V., Sullivan, T.J., Young, T.R., Gelfand, E.T., et al. The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans. Science 348 (2015), 648–660.
    • (2015) Science , vol.348 , pp. 648-660
    • Ardlie, K.G.1    Deluca, D.S.2    Segrè, A.V.3    Sullivan, T.J.4    Young, T.R.5    Gelfand, E.T.6
  • 28
    • 84993993658 scopus 로고    scopus 로고
    • Chromosome conformation elucidates regulatory relationships in developing human brain
    • Won, H., de la Torre-Ubieta, L., Stein, J.L., Parikshak, N.N., Huang, J., Opland, C.K., et al. Chromosome conformation elucidates regulatory relationships in developing human brain. Nature 538 (2016), 523–527.
    • (2016) Nature , vol.538 , pp. 523-527
    • Won, H.1    de la Torre-Ubieta, L.2    Stein, J.L.3    Parikshak, N.N.4    Huang, J.5    Opland, C.K.6
  • 29
    • 85042796965 scopus 로고    scopus 로고
    • Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights
    • [published online ahead of print Aug 2]
    • Gusev, A., Mancuso, N., Finucane, H.K., Reshef, Y., Song, L., Safi, A., et al. Transcriptome-wide association study of schizophrenia and chromatin activity yields mechanistic disease insights. [published online ahead of print Aug 2] bioRxiv, 2016.
    • (2016) bioRxiv
    • Gusev, A.1    Mancuso, N.2    Finucane, H.K.3    Reshef, Y.4    Song, L.5    Safi, A.6
  • 30
    • 80051552041 scopus 로고    scopus 로고
    • The false-positive to false-negative ratio in epidemiologic studies
    • Ioannidis, J.P.A., Tarone, R., McLaughlin, J.K., The false-positive to false-negative ratio in epidemiologic studies. Epidemiology 22 (2011), 450–456.
    • (2011) Epidemiology , vol.22 , pp. 450-456
    • Ioannidis, J.P.A.1    Tarone, R.2    McLaughlin, J.K.3
  • 31
    • 84885391575 scopus 로고    scopus 로고
    • From candidate genes to genome-wide association: The challenges and promise of posttraumatic stress disorder genetic studies
    • Koenen, K.C., Duncan, L.E., Liberzon, I., Ressler, K.J., From candidate genes to genome-wide association: The challenges and promise of posttraumatic stress disorder genetic studies. Biol Psychiatry 74 (2013), 634–636.
    • (2013) Biol Psychiatry , vol.74 , pp. 634-636
    • Koenen, K.C.1    Duncan, L.E.2    Liberzon, I.3    Ressler, K.J.4
  • 32
    • 84965079904 scopus 로고    scopus 로고
    • Time to wake up: No impact of COMT Val158Met gene variation on circadian preferences, arousal regulation and sleep
    • Jawinski, P., Tegelkamp, S., Sander, C., Häntzsch, M., Huang, J., Mauche, N., et al. Time to wake up: No impact of COMT Val158Met gene variation on circadian preferences, arousal regulation and sleep. Chronobiol Int 33 (2016), 893–905.
    • (2016) Chronobiol Int , vol.33 , pp. 893-905
    • Jawinski, P.1    Tegelkamp, S.2    Sander, C.3    Häntzsch, M.4    Huang, J.5    Mauche, N.6
  • 33
    • 84964299963 scopus 로고    scopus 로고
    • Older age may offset genetic influence on affect: The COMT polymorphism and affective well-being across the life span
    • Turan, B., Sims, T., Best, S.E., Carstensen, L.L., Older age may offset genetic influence on affect: The COMT polymorphism and affective well-being across the life span. Psychol Aging 31 (2016), 287–294.
    • (2016) Psychol Aging , vol.31 , pp. 287-294
    • Turan, B.1    Sims, T.2    Best, S.E.3    Carstensen, L.L.4
  • 34
    • 84969165057 scopus 로고    scopus 로고
    • Differences in cognitive outcomes after ECT depending on BDNF and COMT polymorphisms
    • Bennett, D.M., Currie, J., Fernie, G., Perrin, J.S., Reid, I.C., Differences in cognitive outcomes after ECT depending on BDNF and COMT polymorphisms. J ECT 32 (2016), 243–250.
    • (2016) J ECT , vol.32 , pp. 243-250
    • Bennett, D.M.1    Currie, J.2    Fernie, G.3    Perrin, J.S.4    Reid, I.C.5
  • 35
    • 84961901852 scopus 로고    scopus 로고
    • Genetic predisposition to poor opioid response in preterm infants: Impact of KCNJ6 and COMT polymorphisms on pain relief after endotracheal intubation
    • Elens, L., Elisabeth, N., Maja, M., Rane, A., Fellman, V., van Schaik, R.H., Genetic predisposition to poor opioid response in preterm infants: Impact of KCNJ6 and COMT polymorphisms on pain relief after endotracheal intubation. Ther Drug Monit 38 (2016), 525–533.
    • (2016) Ther Drug Monit , vol.38 , pp. 525-533
    • Elens, L.1    Elisabeth, N.2    Maja, M.3    Rane, A.4    Fellman, V.5    van Schaik, R.H.6
  • 37
    • 84863980709 scopus 로고    scopus 로고
    • Genetic architectures of psychiatric disorders: The emerging picture and its implications
    • Sullivan, P.F., Daly, M.J., O'Donovan, M., Genetic architectures of psychiatric disorders: The emerging picture and its implications. Nat Rev Genet 13 (2012), 537–551.
    • (2012) Nat Rev Genet , vol.13 , pp. 537-551
    • Sullivan, P.F.1    Daly, M.J.2    O'Donovan, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.