Critical role of endogenous histamine in promoting end-organ tissue injury in sepsis

Intensive Care Medicine Experimental

Volumn 4, Issue 1, 2016, Pages

  Hattori, Mizuki ^a   Yamazaki, Mitsuaki ^a   Ohashi, Wakana ^a   Tanaka, Satoshi ^b   Hattori, Kohshi ^c   Todoroki, Kenichiro ^d   Fujimori, Toshio ^a   Ohtsu, Hiroshi ^e   Matsuda, Naoyuki ^f   Hattori, Yuichi ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b OKAYAMA UNIVERSITY   (Japan)

^c UNIVERSITY OF TOKYO HOSPITAL   (Japan)

^d UNIVERSITY OF SHIZUOKA   (Japan)

^e TOHOKU UNIVERSITY   (Japan)

^f NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

Histamine; Histidine decarboxylase; Organ injury; Sepsis

Indexed keywords

ALANINE AMINOTRANSFERASE; ASPARTATE AMINOTRANSFERASE; DEXCHLORPHENIRAMINE; FAMOTIDINE; HISTAMINE; HISTIDINE DECARBOXYLASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; INTERLEUKIN 6; MONOCYTE CHEMOTACTIC PROTEIN 1; TUMOR NECROSIS FACTOR;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CECAL LIGATION AND PUNCTURE-INDUCED SEPSIS; CONTROLLED STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; KIDNEY INJURY; LIVER INJURY; LUNG INJURY; LUNG WET TO DRY WEIGHT RATIO; MALE; MOUSE; NONHUMAN; ORGAN INJURY; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; RESPIRATORY TRACT PARAMETERS; RNA EXTRACTION; SIGNAL TRANSDUCTION; SURVIVAL RATE; TISSUE INJURY; UREA NITROGEN BLOOD LEVEL; WESTERN BLOTTING;

EID: 85027399191     PISSN: None     EISSN: 2197425X     Source Type: Journal    
DOI: 10.1186/s40635-016-0109-y     Document Type: Article

References (43)

1. Wang HE, Shapiro NI, Angus DC, Yealy DM (2007) National estimates of severe sepsis in Unites States emergency departments. Crit Care Med 35:1928–1936
2. Angus DC, van der Poll T (2013) Severe sepsis and septic shock. N Engl J Med 369:840–851
3. Singer M, Deutschman CS, Seymour CW, Shankar-Hari M, Annane D, Bauer M, Bellomo R, Bernard GR, Chiche JD, Coopersmith CM, Hotchkiss RS, Levy MM, Marshall JC, Martin GS, Opal SM, Rubenfeld GD, van der Poll T, Vincent JL, Angus DC (2016) The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). JAMA 315:801–810
4. Gustot T (2011) Multiple organ failure in sepsis: prognosis and role of systemic inflammatory response. Curr Opin Crit Care 17:153–159
5. Deutschman CS, Tracey KJ (2014) Sepsis: current dogma and new perspectives. Immunity 40:463–475
6. Rossaint J, Zarbock A (2015) Pathogenesis of multiple organ failure in sepsis. Crit Rev Immunol 35:277–291
7. Neugebauer E, Lorenz W, Rixen D, Stinner B, Sauer S, Dietz W (1996) Histamine release in sepsis: a prospective, controlled, clinical study. Crit Care Med 24:1670–1677
8. 2-receptor gene expression during endotoxemia. Naunyn-Schmiedeberg’s Arch Pharmacol 366:513–521
9. Matsuda N, Hattori Y, Takahashi Y, Nishihira J, Jesmin S, Kobayashi M, Gando S (2004) Therapeutic effect of in vivo transfection of transcription factor decoy to NF-κB on septic lung in mice. Am J Physiol Lung Cell Mol Physiol 287:L1248–L1255
10. 4 receptors contributes to splenic apoptosis in septic mice: Counteraction of antiapoptotic action of nuclear factor-κB. J Pharmacol Exp Ther 332:730–737
11. 1-receptors. J Pharmacol Exp Ther 307:175–181
12. Panula P, Chazot PL, Cowart M, Gutzmer R, Leurs R, Liu WL, Stark H, Thurmond RL, Haas HL (2015) International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors. Pharmacol Rev 67:601–655
13. Hubbard WJ, Choudhry M, Schwacha MG, Kerby JD, Rue LW 3rd, Bland KI, Chaudry IH (2005) Cecal ligation and puncture. Shock 24(Suppl 1):52–57
14. Ohtsu H, Tanaka S, Terui T, Hori Y, Makabe-Kobayashi Y, Pejler G, Tchougounova E, Hellman L, Gertsenstein M, Hirasawa N, Sakurai E, Buzás E, Kovács P, Csaba G, Kittel A, Okada M, Hara M, Mar L, Numayama-Tsuruta K, Ishigaki-Suzuki S, Ohuchi K, Ichikawa A, Falus A, Watanabe T, Nagy A (2001) Mice lacking histidine decarboxylase exhibit abnormal mast cells. FEBS Lett 502:53–56
15. 1 receptors. Proc Natl Acad Sci U S A 93:13316–13320
16. Kobayashi T, Tonai S, Ishihara Y, Koga R, Okabe S, Watanabe T (2000) Abnormal functional and morphological regulation of the gastric mucosa in histamine H2 receptor-deficient mice. J Clin Invest 105:1741–1749
17. Oishi H, Takano K, Tomita K, Takebe M, Yokoo H, Yamazaki M, Hattori Y (2012) Olprinone and colforsin daropate alleviate septic lung inflammation and apoptosis through CREB-independent activation of the Akt pathway. Am J Physiol Lung Cell Mol Physiol 303:L130–L140
18. Tomita K, Takashina M, Mizuno N, Sakata K, Hattori K, Imura J, Ohashi W, Hattori Y (2015) Cardiac fibroblasts: contributory role in septic cardiac dysfunction. J Surg Res 193:874–887
19. Wang Q, Yokoo H, Takashina M, Sakata K, Ohashi W, Abedelzaher LA, Imaizumi T, Sakamoto T, Hattori K, Matsuda N, Hattori Y (2015) Anti-inflammatory profile of levosimendan in cecal ligation-induced septic mice and in lipopolysaccharide-stimulated macrophages. Crit Care Med 43:e508–e520
20. Takano K, Yamamoto S, Tomita K, Takashina M, Yokoo H, Matsuda N, Takano Y, Hattori Y (2011) Successful treatment of acute lung injury with pitavastatin in septic mice: potential role of glucocorticoid receptor expression in alveolar macrophages. J Pharmacol Exp Ther 336:381–390
21. Yamatodani A, Fukuda H, Wada H, Iwaeda T, Watanabe T (1985) High-performance liquid chromatographic determination of plasma and brain histamine without previous purification of biological samples: cation-exchange chromatography coupled with pot-column derivatization fluorometry. J Chromatogr 344:115–123
22. Matsuda N, Hattori Y, Jesmin S, Gando S (2005) Nuclear factor-κB decoy oligodeoxynucleotides prevent acute lung injury in mice with cecal ligation and puncture-induced sepsis. Mol Pharmacol 67:1018–1025
23. Takebe M, Oishi H, Taguchi K, Aoki Y, Takashina M, Tomita K, Yokoo H, Takano Y, Yamazaki M, Hattori Y (2014) Inhibition of histone deacetylases protects septic mice from lung and splenic apoptosis. J Surg Res 187:559–570
24. Benjamin CF, Hagaboam CM, Kunkel SL (2004) The chronic consequences of severe sepsis. J Leukoc Biol 75:408–412
25. Wang H, Ma S (2008) The cytokine storm and factors determining the sequence and severity of organ dysfunction in multiple organ dysfunction syndrome. Am J Emerg Med 26:711–715
26. Horváth BV, Falus A, Tóth S, Szalai C, Lázár-Molnár E, Holub MC, Buzás E, Nagy A, Fulop AK (2002) Inverse regulation of interleukin-6 (IL-6) and IL-6 receptor in histamine deficient histidine decarboxylase-knock-out mice. Immunol Lett 80:151–154
27. Falus A (1993) Interleukin-6 biosynthesis is increased by histamine in human B-cell and glioblastoma cell lines. Immunology 78:193–196
28. Delneste Y, Lassalle P, Jeannin P, Joseph M, Tonnel AB, Gosset P (1994) Histamine induces IL-6 production by human endothelial cells. Clin Exp Immunol 98:344–349
29. Mor S, Nagler A, Barak V, Handzel ZT, Geller-Bernstein C, Fabian I (1995) Histamine enhances granulocyte-macrophage colony-stimulating factor and interleukin-6 by human peripheral blood mononuclear cells. J Leukoc Biol 58:445–450
30. 2 receptors. J Exp Med 174:281–284
31. Brigham KL, Padove SJ, Bryant D, McKeen CR, Bowers RE (1980) Diphenhydramine reduces endotoxin effects on lung vascular permeability in sheep. J Appl Physiol 49:516–520
32. Kim TH, Yoon HJ, Lim CM, Kim EK, Kim MJ, Koh Y (2005) The role of endogenous histamine on the pathogenesis of the lipopolysaccharide (LPS)-induced, acute lung injury: a pilot study. Inflammation 29:72–80
33. Vannay A, Fekete A, Müller V, Strehlau J, Viklicky O, Veres T, Reusz G, Tulassay T, Szabó AJ (2004) Effects of histamine and the h2 receptor antagonist ranitidine on ischemia-reperfusion acute renal failure: involvement of IL-6 and vascular endothelial growth factor. Kidney Blood Press Res 27:105–113
34. Summers SA, Chan J, Gan PY, Dewage L, Nozaki Y, Steinmetz OM, Nikolic-Paterson DJ, Kitching AR, Holdsworth SR (2011) Mast cells mediate acute kidney injury through the production of TNF. J Am Soc Nephrol 22:2226–2236
35. Liu SF, Malik AB (2006) NF-κB activation as a pathological mechanism of septic shock and inflammation. Am J Physiol Lung Cell Mol Physiol 290:L622–L645
36. Abraham E (2003) Nuclear factor-kappaB and its role in sepsis-associated organ failure. J Infect Dis 187(Suppl 2):S364–S369
37. 2 receptor in LPS-induced liver injury. FASEB J 19:1245–1252
38. Hornyak SC, Gehlsen KR, Haaparanta T (2003) Histamine dihydrochloride protects against early alcohol-induced liver injury in a rat model. Inflammation 27:317–327
39. St Peter SD, Sharp SW, Ostlie DJ (2010) Influence of histamine receptor antagonists on the outcome of perforated appendicitis: analysis from a prospective trial. Arch Surg 145:143–146
40. Brett S (2005) Science review: The use of proton pump inhibitors for gastric acid suppression in critical illness. Crit Care 9:45–50
41. Marik PE, Vasu T, Hirani A, Pachinburavan M (2010) Stress ulcer prophylaxis in the new millennium: a systematic review and meta-analysis. Crit Care Med 38:2222–2228
42. Herzig SJ, Howell MD, Ngo LH, Marcantonio ER (2009) Acid-suppressive medication use and the risk for hospital-acquired pneumonia. JAMA 301:2120–2128
43. Alhazzani W, Alenezi F, Jaeschke RZ, Moayyedi P, Cook DJ (2013) Proton pump inhibitors versus histamine 2 receptor antagonists for stress ulcer prophylaxis in critically ill patients: a systematic review and meta-analysis. Crit Care Med 41:693–705