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Volumn 38, Issue 20, 2017, Pages 1553-1560

Lipoprotein(a): The revenant

Author keywords

Cardiovascular prevention; Lipids; Pharmacological therapies; Risk factors

Indexed keywords

HYPOCHOLESTEROLEMIC AGENT; LIPID; LIPOPROTEIN A; LOW DENSITY LIPOPROTEIN CHOLESTEROL; ANTILIPEMIC AGENT; ANTISENSE OLIGONUCLEOTIDE; PCSK9 PROTEIN, HUMAN; PROPROTEIN CONVERTASE 9;

EID: 85027362309     PISSN: 0195668X     EISSN: 15229645     Source Type: Journal    
DOI: 10.1093/eurheartj/ehx033     Document Type: Review
Times cited : (132)

References (48)
  • 3
    • 67049167090 scopus 로고    scopus 로고
    • Genetically elevated lipoprotein(a) and increased risk of myocardial infarction
    • Kamstrup PR, Tybjaerg-Hansen A, Steffensen R, Nordestgaard BG. Genetically elevated lipoprotein(a) and increased risk of myocardial infarction. JAMA 2009;301:2331–2339.
    • (2009) JAMA , vol.301 , pp. 2331-2339
    • Kamstrup, P.R.1    Tybjaerg-Hansen, A.2    Steffensen, R.3    Nordestgaard, B.G.4
  • 5
    • 84929897016 scopus 로고    scopus 로고
    • Sweetless’n low ldl-c targets for pcsk9 treatment
    • Gencer B, Mach F. Sweetless’n low ldl-c targets for pcsk9 treatment. Eur Heart J 2015;36:1146–1148.
    • (2015) Eur Heart J , vol.36 , pp. 1146-1148
    • Gencer, B.1    Mach, F.2
  • 8
    • 84971238069 scopus 로고    scopus 로고
    • Lipoprotein (a): Truly a direct prothrombotic factor in cardiovascular disease?
    • Boffa MB, Koschinsky ML. Lipoprotein (a): truly a direct prothrombotic factor in cardiovascular disease? J Lipid Res 2016;57:745–757.
    • (2016) J Lipid Res , vol.57 , pp. 745-757
    • Boffa, M.B.1    Koschinsky, M.L.2
  • 9
    • 85027946492 scopus 로고    scopus 로고
    • Genetic evidence that lipoprotein(a) associates with atherosclerotic stenosis rather than venous thrombosis
    • Kamstrup PR, Tybjaerg-Hansen A, Nordestgaard BG. Genetic evidence that lipoprotein(a) associates with atherosclerotic stenosis rather than venous thrombosis. Arteriosclerosis, Thromb Vasc Biol 2012;32:1732–1741.
    • (2012) Arteriosclerosis, Thromb Vasc Biol , vol.32 , pp. 1732-1741
    • Kamstrup, P.R.1    Tybjaerg-Hansen, A.2    Nordestgaard, B.G.3
  • 14
    • 84951821405 scopus 로고    scopus 로고
    • Elevated lipoprotein(a) levels, lpa risk genotypes, and increased risk of heart failure in the general population
    • Kamstrup PR, Nordestgaard BG. Elevated lipoprotein(a) levels, lpa risk genotypes, and increased risk of heart failure in the general population. JACC Heart Fail 2016;4:78–87.
    • (2016) JACC Heart Fail , vol.4 , pp. 78-87
    • Kamstrup, P.R.1    Nordestgaard, B.G.2
  • 15
    • 0025365313 scopus 로고
    • Relation of serum lipoprotein(a) concentration and apolipoprotein(a) phenotype to coronary heart disease in patients with familial hypercholesterolemia
    • Seed M, Hoppichler F, Reaveley D, McCarthy S, Thompson GR, Boerwinkle E, Utermann G. Relation of serum lipoprotein(a) concentration and apolipoprotein(a) phenotype to coronary heart disease in patients with familial hypercholesterolemia. N Engl J Med 1990;322:1494–1499.
    • (1990) N Engl J Med , vol.322 , pp. 1494-1499
    • Seed, M.1    Hoppichler, F.2    Reaveley, D.3    McCarthy, S.4    Thompson, G.R.5    Boerwinkle, E.6    Utermann, G.7
  • 19
    • 77951637599 scopus 로고    scopus 로고
    • Apolipoprotein(a) isoforms and the risk of vascular disease: Systematic review of 40 studies involving 58,000 participants
    • Erqou S, Thompson A, Di Angelantonio E, Saleheen D, Kaptoge S, Marcovina S, Danesh J. Apolipoprotein(a) isoforms and the risk of vascular disease: systematic review of 40 studies involving 58,000 participants. J Am Coll Cardiol 2010;55:2160–2167.
    • (2010) J Am Coll Cardiol , vol.55 , pp. 2160-2167
    • Erqou, S.1    Thompson, A.2    Di Angelantonio, E.3    Saleheen, D.4    Kaptoge, S.5    Marcovina, S.6    Danesh, J.7
  • 21
    • 84877155652 scopus 로고    scopus 로고
    • Extreme lipoprotein(a) levels and improved cardiovascular risk prediction
    • Kamstrup PR, Tybjaerg-Hansen A, Nordestgaard BG. Extreme lipoprotein(a) levels and improved cardiovascular risk prediction. J Am Coll Cardiol 2013;61:1146–1156.
    • (2013) J Am Coll Cardiol , vol.61 , pp. 1146-1156
    • Kamstrup, P.R.1    Tybjaerg-Hansen, A.2    Nordestgaard, B.G.3
  • 25
    • 84955473166 scopus 로고    scopus 로고
    • Plasma lipoprotein(a) predicts major cardiovascular events in patients with chronic kidney disease who undergo percutaneous coronary intervention
    • Konishi H, Miyauchi K, Tsuboi S, Ogita M, Naito R, Dohi T, Kasai T, Tamura H, Okazaki S, Isoda K, Daida H. Plasma lipoprotein(a) predicts major cardiovascular events in patients with chronic kidney disease who undergo percutaneous coronary intervention. Int J Cardiol 2016;205:50–53.
    • (2016) Int J Cardiol , vol.205 , pp. 50-53
    • Konishi, H.1    Miyauchi, K.2    Tsuboi, S.3    Ogita, M.4    Naito, R.5    Dohi, T.6    Kasai, T.7    Tamura, H.8    Okazaki, S.9    Isoda, K.10    Daida, H.11
  • 26
    • 84995554827 scopus 로고    scopus 로고
    • Lipoprotein(a) interactions with low-density lipoprotein cholesterol and other cardiovascular risk factors in premature acute coronary syndrome (acs)
    • Afshar M, Pilote L, Dufresne L, Engert JC, Thanassoulis G. Lipoprotein(a) interactions with low-density lipoprotein cholesterol and other cardiovascular risk factors in premature acute coronary syndrome (acs). J Am Heart Assoc 2016;5.
    • (2016) J Am Heart Assoc , vol.5
    • Afshar, M.1    Pilote, L.2    Dufresne, L.3    Engert, J.C.4    Thanassoulis, G.5
  • 29
    • 84893333521 scopus 로고    scopus 로고
    • Elevated lipoprotein(a) and risk of aortic valve stenosis in the general population
    • Kamstrup PR, Tybjaerg-Hansen A, Nordestgaard BG. Elevated lipoprotein(a) and risk of aortic valve stenosis in the general population. J Am Coll Cardiol 2014;63:470–477.
    • (2014) J Am Coll Cardiol , vol.63 , pp. 470-477
    • Kamstrup, P.R.1    Tybjaerg-Hansen, A.2    Nordestgaard, B.G.3
  • 31
    • 0242331117 scopus 로고    scopus 로고
    • Report of the national heart, lung, and blood institute workshop on lipoprotein(a) and cardiovascular disease: Recent advances and future directions
    • Marcovina SM, Koschinsky ML, Albers JJ, Skarlatos S. Report of the national heart, lung, and blood institute workshop on lipoprotein(a) and cardiovascular disease: recent advances and future directions. Clin Chem 2003;49:1785–1796.
    • (2003) Clin Chem , vol.49 , pp. 1785-1796
    • Marcovina, S.M.1    Koschinsky, M.L.2    Albers, J.J.3    Skarlatos, S.4
  • 32
    • 84893853699 scopus 로고    scopus 로고
    • Lipoprotein(a) concentrations, rosuvastatin therapy, and residual vascular risk: An analysis from the jupiter trial (justification for the use of statins in prevention: An intervention trial evaluating rosuvastatin)
    • Khera AV, Everett BM, Caulfield MP, Hantash FM, Wohlgemuth J, Ridker PM, Mora S. Lipoprotein(a) concentrations, rosuvastatin therapy, and residual vascular risk: an analysis from the jupiter trial (justification for the use of statins in prevention: an intervention trial evaluating rosuvastatin). Circulation 2014;129: 635–642.
    • (2014) Circulation , vol.129 , pp. 635-642
    • Khera, A.V.1    Everett, B.M.2    Caulfield, M.P.3    Hantash, F.M.4    Wohlgemuth, J.5    Ridker, P.M.6    Mora, S.7
  • 33
    • 84964282395 scopus 로고    scopus 로고
    • Effect of therapeutic interventions on oxidized phospholipids on apolipoprotein b100 and lipoprotein(a)
    • Yeang C, Hung MY, Byun YS, Clopton P, Yang X, Witztum JL, Tsimikas S. Effect of therapeutic interventions on oxidized phospholipids on apolipoprotein b100 and lipoprotein(a). J Clin Lipidol 2016;10:594–603.
    • (2016) J Clin Lipidol , vol.10 , pp. 594-603
    • Yeang, C.1    Hung, M.Y.2    Byun, Y.S.3    Clopton, P.4    Yang, X.5    Witztum, J.L.6    Tsimikas, S.7
  • 34
    • 84886070404 scopus 로고    scopus 로고
    • Relationship of apolipoproteins a-1 and b, and lipoprotein(a) to cardiovascular outcomes: The aim-high trial (atherothrombosis intervention in metabolic syndrome with low hdl/high triglyceride and impact on global health outcomes)
    • Albers JJ, Slee A, O’brien KD, Robinson JG, Kashyap ML, Kwiterovich PO Jr, Xu P, Marcovina SM. Relationship of apolipoproteins a-1 and b, and lipoprotein(a) to cardiovascular outcomes: the aim-high trial (atherothrombosis intervention in metabolic syndrome with low hdl/high triglyceride and impact on global health outcomes). J Am Coll Cardiol 2013;62:1575–1579.
    • (2013) J Am Coll Cardiol , vol.62 , pp. 1575-1579
    • Albers, J.J.1    Slee, A.2    O’Brien, K.D.3    Robinson, J.G.4    Kashyap, M.L.5    Kwiterovich, P.O.6    Xu, P.7    Marcovina, S.M.8
  • 36
    • 84871674237 scopus 로고    scopus 로고
    • Lipoprotein(a): Resurrected by genetics
    • Kronenberg F, Utermann G. Lipoprotein(a): resurrected by genetics. J Intern Med 2013;273:6–30.
    • (2013) J Intern Med , vol.273 , pp. 6-30
    • Kronenberg, F.1    Utermann, G.2
  • 38
    • 84908363070 scopus 로고    scopus 로고
    • Effect of alirocumab, a monoclonal proprotein convertase subtilisin/kexin 9 antibody, on lipoprotein(a) concentrations (a pooled analysis of 150 mg every two weeks dosing from phase 2 trials)
    • Gaudet D, Kereiakes DJ, McKenney JM, Roth EM, Hanotin C, Gipe D, Du Y, Ferrand AC, Ginsberg HN, Stein EA. Effect of alirocumab, a monoclonal proprotein convertase subtilisin/kexin 9 antibody, on lipoprotein(a) concentrations (a pooled analysis of 150 mg every two weeks dosing from phase 2 trials). Am J Cardiol 2014;114:711–715.
    • (2014) Am J Cardiol , vol.114 , pp. 711-715
    • Gaudet, D.1    Kereiakes, D.J.2    McKenney, J.M.3    Roth, E.M.4    Hanotin, C.5    Gipe, D.6    Du, Y.7    Ferrand, A.C.8    Ginsberg, H.N.9    Stein, E.A.10
  • 40
    • 84960464002 scopus 로고    scopus 로고
    • Use and role of monoclonal antibodies and other biologics in preventive cardiology
    • Gencer B, Laaksonen R, Buhayer A, Mach F. Use and role of monoclonal antibodies and other biologics in preventive cardiology. Swiss Med Week 2015;145:w14179.
    • (2015) Swiss Med Week , vol.145 , pp. w14179
    • Gencer, B.1    Laaksonen, R.2    Buhayer, A.3    Mach, F.4
  • 41
    • 84963934456 scopus 로고    scopus 로고
    • Antisense inhibition of apolipoprotein (a) to lower plasma lipoprotein (a) levels in humans
    • Graham MJ, Viney N, Crooke RM, Tsimikas S. Antisense inhibition of apolipoprotein (a) to lower plasma lipoprotein (a) levels in humans. J Lipid Res 2016;57:340–351.
    • (2016) J Lipid Res , vol.57 , pp. 340-351
    • Graham, M.J.1    Viney, N.2    Crooke, R.M.3    Tsimikas, S.4
  • 42
    • 84921866616 scopus 로고    scopus 로고
    • Mipomersen, an antisense oligonucleotide to apolipoprotein b-100, reduces lipoprotein(a) in various populations with hypercholesterolemia: Results of 4 phase III trials
    • Santos RD, Raal FJ, Catapano AL, Witztum JL, Steinhagen-Thiessen E, Tsimikas S. Mipomersen, an antisense oligonucleotide to apolipoprotein b-100, reduces lipoprotein(a) in various populations with hypercholesterolemia: results of 4 phase iii trials. Arterioscl Thromb Vasc Biol 2015;35:689–699.
    • (2015) Arterioscl Thromb Vasc Biol , vol.35 , pp. 689-699
    • Santos, R.D.1    Raal, F.J.2    Catapano, A.L.3    Witztum, J.L.4    Steinhagen-Thiessen, E.5    Tsimikas, S.6
  • 48
    • 84877299845 scopus 로고    scopus 로고
    • Hps2-thrive randomized placebo-controlled trial in 25 673 high-risk patients of er niacin/laropiprant: Trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment
    • HPS2-THRIVE Collaborative Group. Hps2-thrive randomized placebo-controlled trial in 25 673 high-risk patients of er niacin/laropiprant: trial design, pre-specified muscle and liver outcomes, and reasons for stopping study treatment. Eur Heart J 2013;34:1279–1291.
    • (2013) Eur Heart J , vol.34 , pp. 1279-1291


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.