Activated NK cells cause placental dysfunction and miscarriages in fetal alloimmune thrombocytopenia

Nature Communications

Volumn 8, Issue 1, 2017, Pages

  Yougbaré, Issaka ^a,b   Tai, Wei She ^a   Zdravic, Darko ^a,b,c   Oswald, Brigitta Elaine ^a,b,c   Lang, Sean ^a,b,c   Zhu, Guangheng ^a   Leong Poi, Howard ^d   Qu, Dawei ^e   Yu, Lisa ^e   Dunk, Caroline ^e   Zhang, Jianhong ^e   Sled, John G ^c,e,f   Lye, Stephen J ^c,e   Brkić, Jelena ^g   Peng, Chun ^g   Höglund, Petter ^h   Croy, B Anne ⁱ   Adamson, S Lee ^c,e   Wen, Xiao Yan ^a,c   Stewart, Duncan J ^j   Freedman, John ^a,c   Ni, Heyu ^a,b,c   more..

^a ST MICHAEL'S HOSPITAL   (Canada)

^b CANADIAN BLOOD SERVICES   (Canada)

^c UNIVERSITY OF TORONTO   (Canada)

^d ST MICHAEL'S HOSPITAL   (Canada)

^e MOUNT SINAI HOSPITAL   (Canada)

^f HOSPITAL FOR SICK CHILDREN RESEARCH INSTITUTE   (Canada)

^g YORK UNIVERSITY   (Canada)

^h KAROLINSKA INSTITUTE   (Sweden)

ⁱ QUEEN S UNIVERSITY   (Canada)

^j OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

more..

Author keywords

[No Author keywords available]

Indexed keywords

LYSOSOME ASSOCIATED MEMBRANE PROTEIN 1; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; PERFORIN; THROMBOCYTE ANTIGEN; BETA3 INTEGRIN;

APOPTOSIS; CELLS AND CELL COMPONENTS; GENE EXPRESSION; IMMUNE RESPONSE; PATHOLOGY; PREGNANCY; RODENT;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBODY DEPENDENT CELLULAR CYTOTOXICITY; APOPTOSIS; ARTICLE; CELL SURVIVAL; CONTROLLED STUDY; FEMALE; FETUS; HUMAN; HUMAN CELL; IN VIVO STUDY; LYMPHOCYTE ACTIVATION; MOUSE; NATURAL KILLER CELL; NEONATAL ALLOIMMUNE THROMBOCYTOPENIA; NONHUMAN; PLACENTA DISORDER; PROTEIN SECRETION; SPONTANEOUS ABORTION; TROPHOBLAST; VASCULAR REMODELING; ANIMAL; CELL LINE; DISEASE MODEL; IMMUNOLOGY; INTRAUTERINE GROWTH RETARDATION; MALE; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; PLACENTA; PREGNANCY;

MURINAE;

ABORTION, SPONTANEOUS; ANIMALS; APOPTOSIS; CELL LINE; DISEASE MODELS, ANIMAL; FEMALE; FETAL GROWTH RETARDATION; HUMANS; INTEGRIN BETA3; KILLER CELLS, NATURAL; MALE; MICE; NATURAL CYTOTOXICITY TRIGGERING RECEPTOR 1; PLACENTA; PREGNANCY; THROMBOCYTOPENIA, NEONATAL ALLOIMMUNE;

EID: 85027180409     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/s41467-017-00269-1     Document Type: Article

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