Telomere length in newborns is related to maternal stress during pregnancy

Neuropsychopharmacology

Volumn 42, Issue 12, 2017, Pages 2407-2413

  Send, Tabea Sarah ^a   Gilles, Maria ^a   Codd, Veryan ^b   Wolf, Isabell ^a   Bardtke, Svenja ^a   Streit, Fabian ^a   Strohmaier, Jana ^a   Frank, Josef ^a   Schendel, Darja ^a   Sütterlin, Mark W ^c   Denniff, Matthew ^b   Laucht, Manfred ^a,d   Samani, Nilesh J ^b   Deuschle, Michael ^a   Rietschel, Marcella ^a   Witt, Stephanie H ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF LEICESTER   (United Kingdom)

^c UNIVERSITY OF HEIDELBERG   (Germany)

^d UNIVERSITY OF POTSDAM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; FEMALE; HUMAN; MALE; MATERNAL STRESS; MENTAL DISEASE; NEWBORN; PATERNAL AGE; PREGNANCY; PRENATAL DEVELOPMENT; PRENATAL STRESS; PRIORITY JOURNAL; SELF REPORT; TELOMERE LENGTH; ADULT; COHORT ANALYSIS; COMPLICATION; GENETICS; MENTAL STRESS; PHYSIOLOGY; PREGNANCY COMPLICATION; PROSPECTIVE STUDY; PSYCHOLOGY; TELOMERE; TELOMERE SHORTENING;

ADULT; COHORT STUDIES; FEMALE; HUMANS; INFANT, NEWBORN; MALE; PREGNANCY; PREGNANCY COMPLICATIONS; PROSPECTIVE STUDIES; SELF REPORT; STRESS, PSYCHOLOGICAL; TELOMERE; TELOMERE SHORTENING;

EID: 85026859035     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2017.73     Document Type: Article

References (43)

1. Bann CM, Parker CB, Grobman WA, Willinger M, Simhan HN, Wing DA et al (2017). Psychometric properties of stress and anxiety measures among nulliparous women. J Psychosom Obstet Gynaecol 38: 53-62.
2. Barker DJ (1995). Fetal origins of coronary heart disease. Bmj 311: 171-174.
3. Barker DJ (2002). Fetal programming of coronary heart disease. Trends Endocrinol Metab 13: 364-368.
4. Barker DJ, Thornburg KL (2013). The obstetric origins of health for a lifetime. Clin Obstet Gynecol 56: 511-519.
5. Beijers R, Buitelaar JK, de Weerth C (2014). Mechanisms underlying the effects of prenatal psychosocial stress on child outcomes: beyond the HPA axis. Eur Child Adolesc Psychiatry 23: 943-956.
6. Bojesen SE (2013). Telomeres and human health. J Intern Med 274: 399-413.
7. Broer L, Codd V, Nyholt DR, Deelen J, Mangino M, Willemsen G et al (2013). Meta-analysis of telomere length in 19, 713 subjects reveals high heritability, stronger maternal inheritance and a paternal age effect. Eur J Hum Genet 21: 1163-1168.
8. Cawthon RM (2002). Telomere measurement by quantitative PCR. Nucleic Acids Res 30: e47.
9. Codd V, Mangino M, van Der Harst P, Braund PS, Kaiser M, Beveridge AJ et al (2010). Common variants near TERC are associated with mean telomere length. Nat Genet 42: 197-199.
10. Codd V, Nelson CP, Albrecht E, Mangino M, Deelen J, Buxton JL et al (2013). Identification of seven loci affecting mean telomere length and their association with disease. Nat Genet 45: 422-427, 427e421-422.
11. Cohen S, Kamarck T, Mermelstein R (1983). A global measure of perceived stress. J Health Soc Behav 24: 385-396.
12. Darrow SM, Verhoeven JE, Revesz D, Lindqvist D, Penninx BW, Delucchi KL et al (2016). The association between psychiatric disorders and telomere length: A meta-analysis involving 14, 827 persons. Psychosom Med 78: 776-787.
13. Dukal H, Frank J, Lang M, Treutlein J, Gilles M, Wolf IA et al (2015). New-born females show higher stress- And genotypeindependent methylation of SLC6A4 than males. Borderline Personal Disord Emot Dysregul 2: 8.
14. Entringer S, Buss C, Wadhwa PD (2015). Prenatal stress, development, health and disease risk: A psychobiological perspective-2015 Curt Richter Award Paper. Psychoneuroendocrinology 62: 366-375.
15. Entringer S, Epel ES, Kumsta R, Lin J, Hellhammer DH, Blackburn EH et al (2011). Stress exposure in intrauterine life is associated with shorter telomere length in young adulthood. Proc Natl Acad Sci USA 108: E513-E518.
16. Entringer S, Epel ES, Lin J, Buss C, Shahbaba B, Blackburn EH et al (2013). Maternal psychosocial stress during pregnancy is associated with newborn leukocyte telomere length. Am J Obstet Gynecol 208: 134.e131-e137.
17. Epel ES, Blackburn EH, Lin J, Dhabhar FS, Adler NE, Morrow JD et al (2004). Accelerated telomere shortening in response to life stress. Proc Natl Acad Sci USA 101: 17312-17315.
18. Factor-Litvak P, Susser E, Kezios K, McKeague I, Kark JD, Hoffman M et al (2016). Leukocyte telomere length in newborns: implications for the role of telomeres in human disease. Pediatrics 137: e20153927.
19. Fransen HP, Peeters PH, Beulens JW, Boer JM, de Wit GA, Onland-Moret NC et al (2016). Exposure to famine at a young age and unhealthy lifestyle behavior later in life. PloS ONE 11: e0156609.
20. Glass D, Parts L, Knowles D, Aviv A, Spector TD (2010). No correlation between childhood maltreatment and telomere length. Biol Psychiatry 68: e21-e22.
21. Haycock PC, Heydon EE, Kaptoge S, Butterworth AS, Thompson A, Willeit P (2014). Leucocyte telomere length and risk of cardiovascular disease: systematic review and meta-analysis. BMJ 349: g4227.
22. Heidinger BJ, Blount JD, Boner W, Griffiths K, Metcalfe NB, Monaghan P (2012). Telomere length in early life predicts lifespan. Proc Natl Acad Sci USA 109: 1743-1748.
23. Hjelmborg JB, Dalgard C, Moller S, Steenstrup T, Kimura M, Christensen K et al (2015). The heritability of leucocyte telomere length dynamics. J Med Genet 52: 297-302.
24. Jansen H, Samani NJ, Schunkert H (2014). Mendelian randomization studies in coronary artery disease. Eur Heart J 35: 1917-1924.
25. Kimura M, Hjelmborg JV, Gardner JP, Bathum L, Brimacombe M, Lu X et al (2008). Telomere length and mortality: A study of leukocytes in elderly Danish twins. Am J Epidemiol 167: 799-806.
26. Lindqvist D, Epel ES, Mellon SH, Penninx BW, Revesz D, Verhoeven JE et al (2015). Psychiatric disorders and leukocyte telomere length: underlying mechanisms linking mental illness with cellular aging. Neurosci Biobehav Rev 55: 333-364.
27. Lupien SJ, McEwen BS, Gunnar MR, Heim C (2009). Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat Rev Neurosci 10: 434-445.
28. Marchetto NM, Glynn RA, Ferry ML, Ostojic M, Wolff SM, Yao R et al (2016). Prenatal stress and newborn telomere length. Am J Obstet Gynecol 215: 94 e91-94 e98.
29. Mathur MB, Epel E, Kind S, Desai M, Parks CG, Sandler DP et al (2016). Perceived stress and telomere length: A systematic review, meta-analysis, and methodologic considerations for advancing the field. Brain Behav Immun 54: 158-169.
30. Nast I, Bolten M, Meinlschmidt G, Hellhammer DH (2013). How to measure prenatal stress? A systematic review of psychometric instruments to assess psychosocial stress during pregnancy. Paediatr Perinat Epidemiol 27: 313-322.
31. Nieratschker V, Massart R, Gilles M, Luoni A, Suderman MJ, Krumm B et al (2014). MORC1 exhibits cross-species differential methylation in association with early life stress as well as genome-wide association with MDD. Transl Psychiatry 4: e429.
32. Oliveira BS, Zunzunegui MV, Quinlan J, Fahmi H, Tu MT, Guerra RO (2016). Systematic review of the association between chronic social stress and telomere length: A life course perspective. Ageing Res Rev 26: 37-52.
33. Osler M, Bendix L, Rask L, Rod NH (2016). Stressful life events and leucocyte telomere length: Do lifestyle factors, somatic and mental health, or low grade inflammation mediate this relationship? Results from a cohort of Danish men born in 1953. Brain Behav Immun 58: 248-253.
34. Plana-Ripoll O, Liu X, Momen NC, Parner E, Olsen J, Li J (2016). Prenatal exposure to maternal stress following bereavement and cardiovascular disease: A nationwide population-based and sibling-matched cohort study. Eur J Prev Cardiol 23: 1018-1028.
35. Sarason IG, Johnson JH, Siegel JM (1978). Assessing the impact of life changes: development of the Life Experiences Survey. J Consult Clin Psychol 46: 932-946.
36. Schiavone S, Colaianna M, Curtis L (2015). Impact of early life stress on the pathogenesis of mental disorders: relation to brain oxidative stress. Curr Pharm Des 21: 1404-1412.
37. Shalev I, Caspi A, Ambler A, Belsky DW, Chapple S, Cohen HJ et al (2014). Perinatal complications and aging indicators by midlife. Pediatrics 134: e1315-e1323.
38. Sheehan DV, Lecrubier Y, Sheehan KH, Amorim P, Janavs J, Weiller E et al (1998). The Mini-International Neuropsychiatric Interview (M.I.N.I.): The development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J Clin Psychiatry 59(Suppl 20): 22-33.
39. Susser ES, Lin SP (1992). Schizophrenia after prenatal exposure to the Dutch Hunger Winter of 1944-1945. Arch General Psychiatry 49: 983-988.
40. Verhoeven JE, van Oppen P, Puterman E, Elzinga B, Penninx BW (2015). The association of early and recent psychosocial life stress with leukocyte telomere length. Psychosom Med 77: 882-891.
41. von Zglinicki T (2002). Oxidative stress shortens telomeres. Trends Biochem Sciences 27: 339-344.
42. Walsh KM, Codd V, Rice T, Nelson CP, Smirnov IV, McCoy LS et al (2015). Longer genotypically-estimated leukocyte telomere length is associated with increased adult glioma risk. Oncotarget 6: 42468-42477.
43. Yali AM, Lobel M (1999). Coping and distress in pregnancy: An investigation of medically high risk women. J Psychosom Obstet Gynaecol 20: 39-52.