-
1
-
-
20244366111
-
Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
-
Dudley ME, Wunderlich JR, Yang JC, et al. Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma. J Clin Oncol. 2005;23(10): 2346-2357.
-
(2005)
J Clin Oncol
, vol.23
, Issue.10
, pp. 2346-2357
-
-
Dudley, M.E.1
Wunderlich, J.R.2
Yang, J.C.3
-
2
-
-
84883704931
-
Enhanced-affinity murine T-cell receptors for tumor/self-antigens can be safe in gene therapy despite surpassing the threshold for thymic selection
-
Schmitt TM, Aggen DH, Stromnes IM, et al. Enhanced-affinity murine T-cell receptors for tumor/self-antigens can be safe in gene therapy despite surpassing the threshold for thymic selection. Blood. 2013;122(3):348-356.
-
(2013)
Blood
, vol.122
, Issue.3
, pp. 348-356
-
-
Schmitt, T.M.1
Aggen, D.H.2
Stromnes, I.M.3
-
3
-
-
84928770388
-
Neoantigens in cancer immunotherapy
-
Schumacher TN, Schreiber RD. Neoantigens in cancer immunotherapy. Science. 2015; 348(6230):69-74.
-
(2015)
Science
, vol.348
, Issue.6230
, pp. 69-74
-
-
Schumacher, T.N.1
Schreiber, R.D.2
-
4
-
-
84882837534
-
Signatures of mutational processes in human cancer
-
Australian Pancreatic Cancer Genome Initiative; ICGC PedBrain. published correction appears in Nature. 2013;502(7470): 258
-
Alexandrov LB, Nik-Zainal S, Wedge DC, et al; Australian Pancreatic Cancer Genome Initiative; ICGC Breast Cancer Consortium; ICGC MMML-Seq Consortium; ICGC PedBrain. Signatures of mutational processes in human cancer [published correction appears in Nature. 2013;502(7470): 258]. Nature. 2013;500(7463):415-421.
-
(2013)
Nature
, vol.500
, Issue.7463
, pp. 415-421
-
-
Alexandrov, L.B.1
Nik-Zainal, S.2
Wedge, D.C.3
-
5
-
-
33749624177
-
Cancer regression in patients after transfer of genetically engineered lymphocytes
-
Morgan RA, Dudley ME, Wunderlich JR, et al. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science. 2006;314(5796):126-129.
-
(2006)
Science
, vol.314
, Issue.5796
, pp. 126-129
-
-
Morgan, R.A.1
Dudley, M.E.2
Wunderlich, J.R.3
-
6
-
-
77952236875
-
Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy
-
GM Bendle, C Linnemann, AI Hooijkaas, et al. Lethal graft-versus-host disease in mouse models of T cell receptor gene therapy. Nat Med. 2010; 16(5):565-570.
-
(2010)
Nat Med
, vol.16
, Issue.5
, pp. 565-570
-
-
Bendle, G.M.1
Linnemann, C.2
Hooijkaas, A.I.3
-
7
-
-
84866725832
-
Augmentation of anti-tumor immunity by adoptive T-cell transfer after allogeneic hematopoietic stem cell transplantation
-
Bleakley M, Turtle CJ, Riddell SR. Augmentation of anti-tumor immunity by adoptive T-cell transfer after allogeneic hematopoietic stem cell transplantation. Expert Rev Hematol. 2012;5(4): 409-425.
-
(2012)
Expert Rev Hematol
, vol.5
, Issue.4
, pp. 409-425
-
-
Bleakley, M.1
Turtle, C.J.2
Riddell, S.R.3
-
8
-
-
65349171937
-
Graft-versus-host disease
-
Ferrara JL, Levine JE, Reddy P, Holler E. Graft-versus-host disease. Lancet. 2009;373(9674): 1550-1561.
-
(2009)
Lancet
, vol.373
, Issue.9674
, pp. 1550-1561
-
-
Ferrara, J.L.1
Levine, J.E.2
Reddy, P.3
Holler, E.4
-
9
-
-
84890169660
-
Adoptive immunotherapy with genetically modified lymphocytes in allogeneic stem cell transplantation
-
Cieri N, Mastaglio S, Oliveira G, Casucci M, Bondanza A, Bonini C. Adoptive immunotherapy with genetically modified lymphocytes in allogeneic stem cell transplantation. Immunol Rev. 2014;257(1):165-180.
-
(2014)
Immunol Rev.
, vol.257
, Issue.1
, pp. 165-180
-
-
Cieri, N.1
Mastaglio, S.2
Oliveira, G.3
Casucci, M.4
Bondanza, A.5
Bonini, C.6
-
10
-
-
84860681545
-
Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer
-
Provasi E, Genovese P, Lombardo A, et al. Editing T cell specificity towards leukemia by zinc finger nucleases and lentiviral gene transfer. Nat Med. 2012;18(5):807-815.
-
(2012)
Nat Med
, vol.18
, Issue.5
, pp. 807-815
-
-
Provasi, E.1
Genovese, P.2
Lombardo, A.3
-
11
-
-
84862496486
-
A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR
-
published correction appears in Blood. 2015;126(22):2527
-
Torikai H, Reik A, Liu PQ, et al. A foundation for universal T-cell based immunotherapy: T cells engineered to express a CD19-specific chimeric-antigen-receptor and eliminate expression of endogenous TCR [published correction appears in Blood. 2015;126(22):2527]. Blood. 2012; 119(24):5697-5705.
-
(2012)
Blood
, vol.119
, Issue.24
, pp. 5697-5705
-
-
Torikai, H.1
Reik, A.2
Liu, P.Q.3
-
12
-
-
85011392403
-
Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells
-
Qasim W, Zhan H, Samarasinghe S, et al. Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells. Sci Transl Med. 2017;9(374):eaaj2013.
-
(2017)
Sci Transl Med
, vol.9
, Issue.374
, pp. eaaj2013
-
-
Qasim, W.1
Zhan, H.2
Samarasinghe, S.3
-
13
-
-
84938963928
-
NY-ESO-1-specific TCR-engineered T cells mediate sustained antigen-specific antitumor effects in myeloma
-
Rapoport AP, Stadtmauer EA, Binder-Scholl GK, et al. NY-ESO-1-specific TCR-engineered T cells mediate sustained antigen-specific antitumor effects in myeloma. Nat Med. 2015;21(8): 914-921.
-
(2015)
Nat Med
, vol.21
, Issue.8
, pp. 914-921
-
-
Rapoport, A.P.1
Stadtmauer, E.A.2
Binder-Scholl, G.K.3
-
14
-
-
15444371764
-
Primary human lymphocytes transduced with NY-ESO-1 antigen-specific TCR genes recognize and kill diverse human tumor cell lines
-
Zhao Y, Zheng Z, Robbins PF, Khong HT, Rosenberg SA, Morgan RA. Primary human lymphocytes transduced with NY-ESO-1 antigen-specific TCR genes recognize and kill diverse human tumor cell lines. J Immunol. 2005; 174(7):4415-4423.
-
(2005)
J Immunol
, vol.174
, Issue.7
, pp. 4415-4423
-
-
Zhao, Y.1
Zheng, Z.2
Robbins, P.F.3
Khong, H.T.4
Rosenberg, S.A.5
Morgan, R.A.6
-
15
-
-
0034661697
-
Identification of NY-ESO-1 peptide analogues capable of improved stimulation of tumor-reactive CTL
-
Chen JL, Dunbar PR, Gileadi U, et al. Identification of NY-ESO-1 peptide analogues capable of improved stimulation of tumor-reactive CTL. J Immunol. 2000;165(2):948-955.
-
(2000)
J Immunol
, vol.165
, Issue.2
, pp. 948-955
-
-
Chen, J.L.1
Dunbar, P.R.2
Gileadi, U.3
-
16
-
-
69049089548
-
The prioritization of cancer antigens: A national cancer institute pilot project for the acceleration of translational research
-
Cheever MA, Allison JP, Ferris AS, et al. The prioritization of cancer antigens: a national cancer institute pilot project for the acceleration of translational research. Clin Cancer Res. 2009; 15(17):5323-5337.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.17
, pp. 5323-5337
-
-
Cheever, M.A.1
Allison, J.P.2
Ferris, A.S.3
-
18
-
-
5144230934
-
NY-ESO-1 expression and immunogenicity in esophageal cancer
-
Fujita S, Wada H, Jungbluth AA, et al. NY-ESO-1 expression and immunogenicity in esophageal cancer. Clin Cancer Res. 2004;10(19):6551-6558.
-
(2004)
Clin Cancer Res
, vol.10
, Issue.19
, pp. 6551-6558
-
-
Fujita, S.1
Wada, H.2
Jungbluth, A.A.3
-
19
-
-
84859328258
-
Cancer/testis antigens are novel targets of immunotherapy for adult T-cell leukemia/ lymphoma
-
Nishikawa H, Maeda Y, Ishida T, et al. Cancer/testis antigens are novel targets of immunotherapy for adult T-cell leukemia/ lymphoma. Blood. 2012;119(13):3097-3104.
-
(2012)
Blood
, vol.119
, Issue.13
, pp. 3097-3104
-
-
Nishikawa, H.1
Maeda, Y.2
Ishida, T.3
-
20
-
-
1642578443
-
Development of an adenoviral vector system with adenovirus serotype 35 tropism; efficient transient gene transfer into primary malignant hematopoietic cells
-
Nilsson M, Ljungberg J, Richter J, et al. Development of an adenoviral vector system with adenovirus serotype 35 tropism; efficient transient gene transfer into primary malignant hematopoietic cells. J Gene Med. 2004;6(6): 631-641.
-
(2004)
J Gene Med
, vol.6
, Issue.6
, pp. 631-641
-
-
Nilsson, M.1
Ljungberg, J.2
Richter, J.3
-
21
-
-
84902315464
-
Targeted genome editing in human repopulating haematopoietic stem cells
-
Genovese P, Schiroli G, Escobar G, et al. Targeted genome editing in human repopulating haematopoietic stem cells. Nature. 2014; 510(7504):235-240.
-
(2014)
Nature
, vol.510
, Issue.7504
, pp. 235-240
-
-
Genovese, P.1
Schiroli, G.2
Escobar, G.3
-
22
-
-
79952304769
-
Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1
-
Robbins PF, Morgan RA, Feldman SA, et al. Tumor regression in patients with metastatic synovial cell sarcoma and melanoma using genetically engineered lymphocytes reactive with NY-ESO-1. J Clin Oncol. 2011;29(7):917-924.
-
(2011)
J Clin Oncol
, vol.29
, Issue.7
, pp. 917-924
-
-
Robbins, P.F.1
Morgan, R.A.2
Feldman, S.A.3
-
23
-
-
0035988776
-
HIV-based vectors. Preparation and use
-
Follenzi A, Naldini L. HIV-based vectors. Preparation and use. Methods Mol Med. 2002;69: 259-274.
-
(2002)
Methods Mol Med.
, vol.69
, pp. 259-274
-
-
Follenzi, A.1
Naldini, L.2
-
24
-
-
0026648439
-
Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clones
-
Riddell SR, Watanabe KS, Goodrich JM, Li CR, Agha ME, Greenberg PD. Restoration of viral immunity in immunodeficient humans by the adoptive transfer of T cell clones. Science. 1992; 257(5067):238-241.
-
(1992)
Science
, vol.257
, Issue.5067
, pp. 238-241
-
-
Riddell, S.R.1
Watanabe, K.S.2
Goodrich, J.M.3
Li, C.R.4
Agha, M.E.5
Greenberg, P.D.6
-
25
-
-
79959249778
-
IL-7 receptor expression identifies suicide gene-modified allospecific CD81 T cells capable of self-renewal and differentiation into antileukemia effectors
-
Bondanza A, Hambach L, Aghai Z, et al. IL-7 receptor expression identifies suicide gene-modified allospecific CD81 T cells capable of self-renewal and differentiation into antileukemia effectors. Blood. 2011;117(24):6469-6478.
-
(2011)
Blood
, vol.117
, Issue.24
, pp. 6469-6478
-
-
Bondanza, A.1
Hambach, L.2
Aghai, Z.3
-
26
-
-
33344475250
-
Suicide gene therapy of graft-versus-host disease induced by central memory human T lymphocytes
-
Bondanza A, Valtolina V, Magnani Z, et al. Suicide gene therapy of graft-versus-host disease induced by central memory human T lymphocytes. Blood. 2006;107(5):1828-1836.
-
(2006)
Blood
, vol.107
, Issue.5
, pp. 1828-1836
-
-
Bondanza, A.1
Valtolina, V.2
Magnani, Z.3
-
27
-
-
60849098427
-
IL-7 and IL-15 allow the generation of suicide gene-modified alloreactive self-renewing central memory human T lymphocytes
-
Kaneko S, Mastaglio S, Bondanza A, et al. IL-7 and IL-15 allow the generation of suicide gene-modified alloreactive self-renewing central memory human T lymphocytes. Blood. 2009; 113(5):1006-1015.
-
(2009)
Blood
, vol.113
, Issue.5
, pp. 1006-1015
-
-
Kaneko, S.1
Mastaglio, S.2
Bondanza, A.3
-
28
-
-
0347382593
-
Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells
-
Kaech SM, Tan JT, Wherry EJ, Konieczny BT, Surh CD, Ahmed R. Selective expression of the interleukin 7 receptor identifies effector CD8 T cells that give rise to long-lived memory cells. Nat Immunol. 2003;4(12):1191-1198.
-
(2003)
Nat Immunol.
, vol.4
, Issue.12
, pp. 1191-1198
-
-
Kaech, S.M.1
Tan, J.T.2
Wherry, E.J.3
Konieczny, B.T.4
Surh, C.D.5
Ahmed, R.6
-
29
-
-
0036109159
-
Memory CD81 T cells vary in differentiation phenotype in different persistent virus infections
-
Appay V, Dunbar PR, Callan M, et al. Memory CD81 T cells vary in differentiation phenotype in different persistent virus infections. Nat Med. 2002;8(4):379-385.
-
(2002)
Nat Med
, vol.8
, Issue.4
, pp. 379-385
-
-
Appay, V.1
Dunbar, P.R.2
Callan, M.3
-
30
-
-
17844381006
-
Survival, persistence, and progressive differentiation of adoptively transferred tumor-reactive T cells associated with tumor regression
-
Huang J, Khong HT, Dudley ME, et al. Survival, persistence, and progressive differentiation of adoptively transferred tumor-reactive T cells associated with tumor regression. J Immunother. 2005;28(3):258-267.
-
(2005)
J Immunother
, vol.28
, Issue.3
, pp. 258-267
-
-
Huang, J.1
Khong, H.T.2
Dudley, M.E.3
-
31
-
-
33745083070
-
CD81 T-cell memory in tumor immunology and immunotherapy
-
Klebanoff CA, Gattinoni L, Restifo NP. CD81 T-cell memory in tumor immunology and immunotherapy. Immunol Rev. 2006;211(1): 214-224.
-
(2006)
Immunol Rev
, vol.211
, Issue.1
, pp. 214-224
-
-
Klebanoff, C.A.1
Gattinoni, L.2
Restifo, N.P.3
-
32
-
-
84904240682
-
Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells
-
Dolton G, Lissina A, Skowera A, et al. Comparison of peptide-major histocompatibility complex tetramers and dextramers for the identification of antigen-specific T cells. Clin Exp Immunol. 2014;177(1):47-63.
-
(2014)
Clin Exp Immunol
, vol.177
, Issue.1
, pp. 47-63
-
-
Dolton, G.1
Lissina, A.2
Skowera, A.3
-
33
-
-
84896734546
-
Immune escape from NY-ESO-1-specific T-cell therapy via loss of heterozygosity in the MHC
-
Klippel ZK, Chou J, Towlerton AM, et al. Immune escape from NY-ESO-1-specific T-cell therapy via loss of heterozygosity in the MHC. Gene Ther. 2014;21(3):337-342.
-
(2014)
Gene Ther
, vol.21
, Issue.3
, pp. 337-342
-
-
Klippel, Z.K.1
Chou, J.2
Towlerton, A.M.3
-
34
-
-
84873050511
-
IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors
-
Cieri N, Camisa B, Cocchiarella F, et al. IL-7 and IL-15 instruct the generation of human memory stem T cells from naive precursors. Blood. 2013; 121(4):573-584.
-
(2013)
Blood
, vol.121
, Issue.4
, pp. 573-584
-
-
Cieri, N.1
Camisa, B.2
Cocchiarella, F.3
-
35
-
-
22144437688
-
Central memory self/tumor-reactive CD81 T cells confer superior antitumor immunity compared with effector memory T cells
-
Klebanoff CA, Gattinoni L, Torabi-Parizi P, et al. Central memory self/tumor-reactive CD81 T cells confer superior antitumor immunity compared with effector memory T cells. Proc Natl Acad Sci USA. 2005;102(27):9571-9576.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, Issue.27
, pp. 9571-9576
-
-
Klebanoff, C.A.1
Gattinoni, L.2
Torabi-Parizi, P.3
-
36
-
-
0033554726
-
Two subsets of memory T lymphocytes with distinct homing potentials and effector functions
-
Sallusto F, Lenig D, Förster R, Lipp M, Lanzavecchia A. Two subsets of memory T lymphocytes with distinct homing potentials and effector functions. Nature. 1999;401(6754): 708-712.
-
(1999)
Nature
, vol.401
, Issue.6754
, pp. 708-712
-
-
Sallusto, F.1
Lenig, D.2
Förster, R.3
Lipp, M.4
Lanzavecchia, A.5
-
37
-
-
20444499355
-
Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD81 T cells
-
Gattinoni L, Klebanoff CA, Palmer DC, et al. Acquisition of full effector function in vitro paradoxically impairs the in vivo antitumor efficacy of adoptively transferred CD81 T cells. J Clin Invest. 2005;115(6):1616-1626.
-
(2005)
J Clin Invest
, vol.115
, Issue.6
, pp. 1616-1626
-
-
Gattinoni, L.1
Klebanoff, C.A.2
Palmer, D.C.3
-
38
-
-
38149117105
-
Adoptive transfer of effector CD81 T cells derived from central memory cells establishes persistent T cell memory in primates
-
Berger C, Jensen MC, Lansdorp PM, Gough M, Elliott C, Riddell SR. Adoptive transfer of effector CD81 T cells derived from central memory cells establishes persistent T cell memory in primates. J Clin Invest. 2008;118(1): 294-305.
-
(2008)
J Clin Invest
, vol.118
, Issue.1
, pp. 294-305
-
-
Berger, C.1
Jensen, M.C.2
Lansdorp, P.M.3
Gough, M.4
Elliott, C.5
Riddell, S.R.6
-
39
-
-
84954438750
-
Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory
-
published correction appears in Sci Transl Med. 2015;7(319): 319er9
-
Oliveira G, Ruggiero E, Stanghellini MT, et al. Tracking genetically engineered lymphocytes long-term reveals the dynamics of T cell immunological memory [published correction appears in Sci Transl Med. 2015;7(319): 319er9]. Sci Transl Med. 2015;7(317): 317ra198.
-
(2015)
Sci Transl Med
, vol.7
, Issue.317
, pp. 317ra198
-
-
Oliveira, G.1
Ruggiero, E.2
Stanghellini, M.T.3
-
40
-
-
44449128698
-
Single and dual amino acid substitutions in TCR CDRs can enhance antigen-specific T cell functions
-
Robbins PF, Li YF, El-Gamil M, et al. Single and dual amino acid substitutions in TCR CDRs can enhance antigen-specific T cell functions. J Immunol. 2008;180(9):6116-6131.
-
(2008)
J Immunol
, vol.180
, Issue.9
, pp. 6116-6131
-
-
Robbins, P.F.1
Li, Y.F.2
El-Gamil, M.3
-
41
-
-
85001733353
-
Preclinical models of acute and chronic graft-versus-host disease: How predictive are they for a successful clinical translation?
-
Zeiser R, Blazar BR. Preclinical models of acute and chronic graft-versus-host disease: how predictive are they for a successful clinical translation? Blood. 2016;127(25): 3117-3126.
-
(2016)
Blood
, vol.127
, Issue.25
, pp. 3117-3126
-
-
Zeiser, R.1
Blazar, B.R.2
|