Hand factor ablation causes defective left ventricular chamber development and compromised adult cardiac function

PLoS Genetics

Volumn 13, Issue 7, 2017, Pages

  Vincentz, Joshua W ^a   Toolan, Kevin P ^a   Zhang, Wenjun ^a   Firulli, Anthony B ^a  

^a INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR HAND1; TRANSCRIPTION FACTOR HAND2; UNCLASSIFIED DRUG; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; HAND1 PROTEIN, MOUSE; HAND2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC MUSCLE CELL; CELL DEATH; CELL LINEAGE; CELL POPULATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; CRE GENE; DEVELOPMENTAL DISORDER; EMBRYO; FEMALE; GENE EXPRESSION; GENE FUNCTION; GENE LOSS; HAND1 GENE; HAND2 GEEN; HEART DEVELOPMENT; HEART DISEASE; HEART FUNCTION; HEART LEFT VENTRICLE; HYPOPLASIA; MALE; MOLECULAR PATHOLOGY; MORPHOGENESIS; MOUSE; MYOCARDIAL DISEASE; NONHUMAN; PROTEIN FUNCTION; REGULATORY MECHANISM; TRANSGENE; ANIMAL; CELL DIFFERENTIATION; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; HEART; HEART VENTRICLE; HUMAN; KNOCKOUT MOUSE; METABOLISM; MUTATION; PATHOLOGY;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL DIFFERENTIATION; CELL LINEAGE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HEART; HEART VENTRICLES; HUMANS; MICE; MICE, KNOCKOUT; MORPHOGENESIS; MUTATION; MYOCYTES, CARDIAC;

EID: 85026645211     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1006922     Document Type: Article

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