메뉴 건너뛰기




Volumn 121, Issue 6, 2017, Pages e22-e36

Paracrine effects of the pluripotent stem cell-derived cardiac myocytes salvage the injured myocardium

Author keywords

Cell therapy; Cytokines; Magnetic resonance imaging; Manganese; Myocardial infarction; Pluripotent stem cells

Indexed keywords

CHEMOKINE RECEPTOR CXCR4; GRANULOCYTE COLONY STIMULATING FACTOR; INTERLEUKIN 8; PLASMINOGEN ACTIVATOR INHIBITOR 1; TROPONIN T; TUMOR NECROSIS FACTOR; VASCULAR CELL ADHESION MOLECULE 1; VASCULOTROPIN; CYTOKINE;

EID: 85026455118     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.117.310803     Document Type: Article
Times cited : (122)

References (61)
  • 1
    • 84885842429 scopus 로고    scopus 로고
    • 2013 ACCF/AHA guideline for the management of heart failure: Executive summary: A report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines
    • Yancy CW, Jessup M, Bozkurt B, et al. 2013 ACCF/AHA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology Foundation/American Heart Association task force on practice guidelines. Circulation. 2013;128:1810-1852. doi: 10.1161/ CIR.0b013e31829e8807.
    • (2013) Circulation , vol.128 , pp. 1810-1852
    • Yancy, C.W.1    Jessup, M.2    Bozkurt, B.3
  • 2
    • 84922381210 scopus 로고    scopus 로고
    • Heart disease and stroke statistics-2015 update: A report from the American Heart Association
    • Mozaffarian D, Benjamin EJ, Go AS, et al; American Heart Association Statistics Committee and Stroke Statistics Subcommittee. Heart disease and stroke statistics-2015 update: a report from the American Heart Association. Circulation. 2015;131:e29-322. doi: 10.1161/CIR. 0000000000000152.
    • (2015) Circulation , vol.131 , pp. e29-322
    • Mozaffarian, D.1    Benjamin, E.J.2    Go, A.S.3
  • 3
    • 0032920779 scopus 로고    scopus 로고
    • Regulation of cardiovascular collagen synthesis by mechanical load
    • Bishop JE, Lindahl G. Regulation of cardiovascular collagen synthesis by mechanical load. Cardiovasc Res. 1999;42:27-44.
    • (1999) Cardiovasc Res , vol.42 , pp. 27-44
    • Bishop, J.E.1    Lindahl, G.2
  • 4
    • 84951142503 scopus 로고    scopus 로고
    • Thrombospondins in the transition from myocardial infarction to heart failure
    • Kirk JA, Cingolani OH. Thrombospondins in the transition from myocardial infarction to heart failure. J Mol Cell Cardiol. 2016;90:102-110. doi: 10.1016/j.yjmcc.2015.12.009.
    • (2016) J Mol Cell Cardiol , vol.90 , pp. 102-110
    • Kirk, J.A.1    Cingolani, O.H.2
  • 5
    • 14644414788 scopus 로고    scopus 로고
    • Unchain my heart: The scientific foundations of cardiac repair
    • Dimmeler S, Zeiher AM, Schneider MD. Unchain my heart: the scientific foundations of cardiac repair. J Clin Invest. 2005;115:572-583. doi: 10.1172/JCI24283.
    • (2005) J Clin Invest , vol.115 , pp. 572-583
    • Dimmeler, S.1    Zeiher, A.M.2    Schneider, M.D.3
  • 6
    • 30944432553 scopus 로고    scopus 로고
    • Cell-based cardiac repair: Reflections at the 10-year point
    • Murry CE, Field LJ, Menasché P. Cell-based cardiac repair: reflections at the 10-year point. Circulation. 2005;112:3174-3183. doi: 10.1161/ CIRCULATIONAHA.105.546218.
    • (2005) Circulation , vol.112 , pp. 3174-3183
    • Murry, C.E.1    Field, L.J.2    Menasché, P.3
  • 7
    • 39749105397 scopus 로고    scopus 로고
    • Stem-cell therapy for cardiac disease
    • Segers VF, Lee RT. Stem-cell therapy for cardiac disease. Nature. 2008;451:937-942. doi: 10.1038/nature06800.
    • (2008) Nature , vol.451 , pp. 937-942
    • Segers, V.F.1    Lee, R.T.2
  • 8
    • 82255175382 scopus 로고    scopus 로고
    • Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): Initial results of a randomised phase 1 trial
    • Bolli R, Chugh AR, D'Amario D, et al. Cardiac stem cells in patients with ischaemic cardiomyopathy (SCIPIO): initial results of a randomised phase 1 trial. Lancet. 2011;378:1847-1857. doi: 10.1016/S0140-6736(11)61590-0.
    • (2011) Lancet , vol.378 , pp. 1847-1857
    • Bolli, R.1    Chugh, A.R.2    D'Amario, D.3
  • 9
    • 80053552289 scopus 로고    scopus 로고
    • Mesenchymal stem cells: Biology, pathophysiology, translational findings, and therapeutic implications for cardiac disease
    • Williams AR, Hare JM. Mesenchymal stem cells: biology, pathophysiology, translational findings, and therapeutic implications for cardiac disease. Circ Res. 2011;109:923-940. doi: 10.1161/CIRCRESAHA.111.243147.
    • (2011) Circ Res , vol.109 , pp. 923-940
    • Williams, A.R.1    Hare, J.M.2
  • 10
    • 84861999021 scopus 로고    scopus 로고
    • Pivotal role of paracrine effects in stem cell therapies in regenerative medicine: Can we translate stem cell-secreted paracrine factors and microvesicles into better therapeutic strategies?
    • Ratajczak MZ, Kucia M, Jadczyk T, Greco NJ, Wojakowski W, Tendera M, Ratajczak J. Pivotal role of paracrine effects in stem cell therapies in regenerative medicine: can we translate stem cell-secreted paracrine factors and microvesicles into better therapeutic strategies? Leukemia. 2012;26:1166-1173. doi: 10.1038/leu.2011.389.
    • (2012) Leukemia , vol.26 , pp. 1166-1173
    • Ratajczak, M.Z.1    Kucia, M.2    Jadczyk, T.3    Greco, N.J.4    Wojakowski, W.5    Tendera, M.6    Ratajczak, J.7
  • 12
    • 34948891467 scopus 로고    scopus 로고
    • Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts
    • Laflamme MA, Chen KY, Naumova AV, et al. Cardiomyocytes derived from human embryonic stem cells in pro-survival factors enhance function of infarcted rat hearts. Nat Biotechnol. 2007;25:1015-1024. doi: 10.1038/ nbt1327.
    • (2007) Nat Biotechnol , vol.25 , pp. 1015-1024
    • Laflamme, M.A.1    Chen, K.Y.2    Naumova, A.V.3
  • 14
    • 43449126812 scopus 로고    scopus 로고
    • Human embryonic stem cell-derived cardiomyocytes and cardiac repair in rodents
    • van Laake LW, Passier R, Doevendans PA, Mummery CL. Human embryonic stem cell-derived cardiomyocytes and cardiac repair in rodents. Circ Res. 2008;102:1008-1010. doi: 10.1161/CIRCRESAHA. 108.175505.
    • (2008) Circ Res , vol.102 , pp. 1008-1010
    • Van Laake, L.W.1    Passier, R.2    Doevendans, P.A.3    Mummery, C.L.4
  • 17
    • 35548974727 scopus 로고    scopus 로고
    • Transplantation of human embryonic stem cell-derived cardiomyocytes improves myocardial performance in infarcted rat hearts
    • Caspi O, Huber I, Kehat I, Habib M, Arbel G, Gepstein A, Yankelson L, Aronson D, Beyar R, Gepstein L. Transplantation of human embryonic stem cell-derived cardiomyocytes improves myocardial performance in infarcted rat hearts. J Am Coll Cardiol. 2007;50:1884-1893. doi: 10.1016/j. jacc.2007.07.054.
    • (2007) J Am Coll Cardiol , vol.50 , pp. 1884-1893
    • Caspi, O.1    Huber, I.2    Kehat, I.3    Habib, M.4    Arbel, G.5    Gepstein, A.6    Yankelson, L.7    Aronson, D.8    Beyar, R.9    Gepstein, L.10
  • 19
    • 84866150446 scopus 로고    scopus 로고
    • Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts
    • Shiba Y, Fernandes S, Zhu WZ, et al. Human ES-cell-derived cardiomyocytes electrically couple and suppress arrhythmias in injured hearts. Nature. 2012;489:322-325. doi: 10.1038/nature11317.
    • (2012) Nature , vol.489 , pp. 322-325
    • Shiba, Y.1    Fernandes, S.2    Zhu, W.Z.3
  • 20
    • 84902312015 scopus 로고    scopus 로고
    • Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts
    • Chong JJ, Yang X, Don CW, et al. Human embryonic-stem-cell-derived cardiomyocytes regenerate non-human primate hearts. Nature. 2014;510:273-277. doi: 10.1038/nature13233.
    • (2014) Nature , vol.510 , pp. 273-277
    • Chong, J.J.1    Yang, X.2    Don, C.W.3
  • 21
    • 84872103748 scopus 로고    scopus 로고
    • Bioengineered myocardium derived from induced pluripotent stem cells improves cardiac function and attenuates cardiac remodeling following chronic myocardial infarction in rats
    • Miki K, Uenaka H, Saito A, Miyagawa S, Sakaguchi T, Higuchi T, Shimizu T, Okano T, Yamanaka S, Sawa Y. Bioengineered myocardium derived from induced pluripotent stem cells improves cardiac function and attenuates cardiac remodeling following chronic myocardial infarction in rats. Stem Cells Transl Med. 2012;1:430-437. doi: 10.5966/sctm.2011-0038.
    • (2012) Stem Cells Transl Med , vol.1 , pp. 430-437
    • Miki, K.1    Uenaka, H.2    Saito, A.3    Miyagawa, S.4    Sakaguchi, T.5    Higuchi, T.6    Shimizu, T.7    Okano, T.8    Yamanaka, S.9    Sawa, Y.10
  • 22
    • 84919460805 scopus 로고    scopus 로고
    • Cardiac repair in a porcine model of acute myocardial infarction with human induced pluripotent stem cell-derived cardiovascular cells
    • Ye L, Chang YH, Xiong Q, et al. Cardiac repair in a porcine model of acute myocardial infarction with human induced pluripotent stem cell-derived cardiovascular cells. Cell Stem Cell. 2014;15:750-761. doi: 10.1016/j. stem.2014.11.009.
    • (2014) Cell Stem Cell , vol.15 , pp. 750-761
    • Ye, L.1    Chang, Y.H.2    Xiong, Q.3
  • 24
    • 54049153577 scopus 로고    scopus 로고
    • Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells
    • e1
    • Hendry SL II, van der Bogt KE, Sheikh AY, et al. Multimodal evaluation of in vivo magnetic resonance imaging of myocardial restoration by mouse embryonic stem cells. J Thorac Cardiovasc Surg. 2008;136:1028-1037. e1. doi: 10.1016/j.jtcvs.2007.12.053.
    • (2008) J Thorac Cardiovasc Surg , vol.136 , pp. 1028-1037
    • Hendry, S.L.1    Van Der Bogt, K.E.2    Sheikh, A.Y.3
  • 25
    • 84883268465 scopus 로고    scopus 로고
    • Stem cells for cardiac repair: An introduction
    • du Pré BC, Doevendans PA, van Laake LW. Stem cells for cardiac repair: an introduction. J Geriatr Cardiol. 2013;10:186-197. doi: 10.3969/j. issn.1671-5411.2013.02.003.
    • (2013) J Geriatr Cardiol , vol.10 , pp. 186-197
    • Du Pré, B.C.1    Doevendans, P.A.2    Van Laake, L.W.3
  • 27
    • 84868154075 scopus 로고    scopus 로고
    • Generation of integrationfree human induced pluripotent stem cells from postnatal blood mononuclear cells by plasmid vector expression
    • Dowey SN, Huang X, Chou BK, Ye Z, Cheng L. Generation of integrationfree human induced pluripotent stem cells from postnatal blood mononuclear cells by plasmid vector expression. Nat Protoc. 2012;7:2013-2021. doi: 10.1038/nprot.2012.121.
    • (2012) Nat Protoc , vol.7 , pp. 2013-2021
    • Dowey, S.N.1    Huang, X.2    Chou, B.K.3    Ye, Z.4    Cheng, L.5
  • 28
    • 84874817493 scopus 로고    scopus 로고
    • An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells
    • Okita K, Yamakawa T, Matsumura Y, Sato Y, Amano N, Watanabe A, Goshima N, Yamanaka S. An efficient nonviral method to generate integration-free human-induced pluripotent stem cells from cord blood and peripheral blood cells. Stem Cells. 2013;31:458-466. doi: 10.1002/stem.1293.
    • (2013) Stem Cells , vol.31 , pp. 458-466
    • Okita, K.1    Yamakawa, T.2    Matsumura, Y.3    Sato, Y.4    Amano, N.5    Watanabe, A.6    Goshima, N.7    Yamanaka, S.8
  • 29
    • 84871539019 scopus 로고    scopus 로고
    • Genome editing of human embryonic stem cells and induced pluripotent stem cells with zinc finger nucleases for cellular imaging
    • Wang Y, Zhang WY, Hu S, et al. Genome editing of human embryonic stem cells and induced pluripotent stem cells with zinc finger nucleases for cellular imaging. Circ Res. 2012;111:1494-1503. doi: 10.1161/ CIRCRESAHA.112.274969.
    • (2012) Circ Res , vol.111 , pp. 1494-1503
    • Wang, Y.1    Zhang, W.Y.2    Hu, S.3
  • 30
    • 80053246998 scopus 로고    scopus 로고
    • Curcumin ((E, E)-1, 7-bis(4-hydroxy-3-methoxyphenyl)-1, 6-heptadiene-3, 5-dione) activates and desensitizes the nociceptor ion channel TRPA1
    • Leamy AW, Shukla P, McAlexander MA, Carr MJ, Ghatta S. Curcumin ((E, E)-1, 7-bis(4-hydroxy-3-methoxyphenyl)-1, 6-heptadiene-3, 5-dione) activates and desensitizes the nociceptor ion channel TRPA1. Neurosci Lett. 2011;503:157-162. doi: 10.1016/j.neulet.2011.07.054.
    • (2011) Neurosci Lett , vol.503 , pp. 157-162
    • Leamy, A.W.1    Shukla, P.2    McAlexander, M.A.3    Carr, M.J.4    Ghatta, S.5
  • 32
    • 31944443231 scopus 로고    scopus 로고
    • Magnetic resonance imaging of myocardial infarction using a manganese-based contrast agent (EVP 1001-1): Preliminary results in a dog model
    • Storey P, Chen Q, Li W, Seoane PR, Harnish PP, Fogelson L, Harris KR, Prasad PV. Magnetic resonance imaging of myocardial infarction using a manganese-based contrast agent (EVP 1001-1): preliminary results in a dog model. J Magn Reson Imaging. 2006;23:228-234. doi: 10.1002/jmri.20500.
    • (2006) J Magn Reson Imaging , vol.23 , pp. 228-234
    • Storey, P.1    Chen, Q.2    Li, W.3    Seoane, P.R.4    Harnish, P.P.5    Fogelson, L.6    Harris, K.R.7    Prasad, P.V.8
  • 38
    • 84883581618 scopus 로고    scopus 로고
    • Cell therapy for heart failure: A comprehensive overview of experimental and clinical studies, current challenges, and future directions
    • Sanganalmath SK, Bolli R. Cell therapy for heart failure: a comprehensive overview of experimental and clinical studies, current challenges, and future directions. Circ Res. 2013;113:810-834. doi: 10.1161/ CIRCRESAHA.113.300219.
    • (2013) Circ Res , vol.113 , pp. 810-834
    • Sanganalmath, S.K.1    Bolli, R.2
  • 39
    • 0034625134 scopus 로고    scopus 로고
    • Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction
    • Kurrelmeyer KM, Michael LH, Baumgarten G, Taffet GE, Peschon JJ, Sivasubramanian N, Entman ML, Mann DL. Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction. Proc Natl Acad Sci USA. 2000;97:5456-5461. doi: 10.1073/pnas.070036297.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 5456-5461
    • Kurrelmeyer, K.M.1    Michael, L.H.2    Baumgarten, G.3    Taffet, G.E.4    Peschon, J.J.5    Sivasubramanian, N.6    Entman, M.L.7    Mann, D.L.8
  • 40
    • 58149347238 scopus 로고    scopus 로고
    • Paracrine mechanisms in adult stem cell signaling and therapy
    • Gnecchi M, Zhang Z, Ni A, Dzau VJ. Paracrine mechanisms in adult stem cell signaling and therapy. Circ Res. 2008;103:1204-1219. doi: 10.1161/ CIRCRESAHA.108.176826.
    • (2008) Circ Res , vol.103 , pp. 1204-1219
    • Gnecchi, M.1    Zhang, Z.2    Ni, A.3    Dzau, V.J.4
  • 45
    • 0345098401 scopus 로고    scopus 로고
    • Cardiomyocytes overexpressing TNF-alpha attract migration of embryonic stem cells via activation of p38 and c-Jun amino-terminal kinase
    • Chen Y, Ke Q, Yang Y, Rana JS, Tang J, Morgan JP, Xiao YF. Cardiomyocytes overexpressing TNF-alpha attract migration of embryonic stem cells via activation of p38 and c-Jun amino-terminal kinase. FASEB J. 2003;17:2231-2239. doi: 10.1096/fj.03-0030com.
    • (2003) FASEB J , vol.17 , pp. 2231-2239
    • Chen, Y.1    Ke, Q.2    Yang, Y.3    Rana, J.S.4    Tang, J.5    Morgan, J.P.6    Xiao, Y.F.7
  • 46
    • 84899508957 scopus 로고    scopus 로고
    • Paracrine effects of stem cells in wound healing and cancer progression (Review)
    • Dittmer J, Leyh B. Paracrine effects of stem cells in wound healing and cancer progression (Review). Int J Oncol. 2014;44:1789-1798. doi: 10.3892/ijo.2014.2385.
    • (2014) Int J Oncol , vol.44 , pp. 1789-1798
    • Dittmer, J.1    Leyh, B.2
  • 48
    • 34547740001 scopus 로고    scopus 로고
    • Mesenchymal stem cells use integrin beta1 not CXC chemokine receptor 4 for myocardial migration and engraftment
    • Ip JE, Wu Y, Huang J, Zhang L, Pratt RE, Dzau VJ. Mesenchymal stem cells use integrin beta1 not CXC chemokine receptor 4 for myocardial migration and engraftment. Mol Biol Cell. 2007;18:2873-2882. doi: 10.1091/mbc.E07-02-0166.
    • (2007) Mol Biol Cell , vol.18 , pp. 2873-2882
    • Ip, J.E.1    Wu, Y.2    Huang, J.3    Zhang, L.4    Pratt, R.E.5    Dzau, V.J.6
  • 49
    • 0037188941 scopus 로고    scopus 로고
    • Role of Akt signaling in vascular homeostasis and angiogenesis
    • Shiojima I, Walsh K. Role of Akt signaling in vascular homeostasis and angiogenesis. Circ Res. 2002;90:1243-1250.
    • (2002) Circ Res , vol.90 , pp. 1243-1250
    • Shiojima, I.1    Walsh, K.2
  • 50
    • 20144388775 scopus 로고    scopus 로고
    • G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes
    • Harada M, Qin Y, Takano H, et al. G-CSF prevents cardiac remodeling after myocardial infarction by activating the Jak-Stat pathway in cardiomyocytes. Nat Med. 2005;11:305-311. doi: 10.1038/nm1199.
    • (2005) Nat Med , vol.11 , pp. 305-311
    • Harada, M.1    Qin, Y.2    Takano, H.3
  • 51
    • 19244379078 scopus 로고    scopus 로고
    • Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions
    • Carmeliet P, Moons L, Luttun A, et al. Synergism between vascular endothelial growth factor and placental growth factor contributes to angiogenesis and plasma extravasation in pathological conditions. Nat Med. 2001;7:575-583. doi: 10.1038/87904.
    • (2001) Nat Med , vol.7 , pp. 575-583
    • Carmeliet, P.1    Moons, L.2    Luttun, A.3
  • 52
    • 52049126184 scopus 로고    scopus 로고
    • Implication of connexins 40 and 43 in functional coupling between mouse cardiac fibroblasts in primary culture
    • Louault C, Benamer N, Faivre JF, Potreau D, Bescond J. Implication of connexins 40 and 43 in functional coupling between mouse cardiac fibroblasts in primary culture. Biochim Biophys Acta. 2008;1778:2097-2104. doi: 10.1016/j.bbamem.2008.04.005.
    • (2008) Biochim Biophys Acta , vol.1778 , pp. 2097-2104
    • Louault, C.1    Benamer, N.2    Faivre, J.F.3    Potreau, D.4    Bescond, J.5
  • 53
    • 34548174756 scopus 로고    scopus 로고
    • Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: Role of the cardiac stromal cell derived factor-1 alpha CXCR4 axis
    • Hu X, Dai S, Wu WJ, Tan W, Zhu X, Mu J, Guo Y, Bolli R, Rokosh G. Stromal cell derived factor-1 alpha confers protection against myocardial ischemia/reperfusion injury: role of the cardiac stromal cell derived factor-1 alpha CXCR4 axis. Circulation. 2007;116:654-663. doi: 10.1161/ CIRCULATIONAHA.106.672451.
    • (2007) Circulation , vol.116 , pp. 654-663
    • Hu, X.1    Dai, S.2    Wu, W.J.3    Tan, W.4    Zhu, X.5    Mu, J.6    Guo, Y.7    Bolli, R.8    Rokosh, G.9
  • 54
    • 35148820656 scopus 로고    scopus 로고
    • Local delivery of protease-resistant stromal cell derived factor-1 for stem cell recruitment after myocardial infarction
    • Segers VF, Tokunou T, Higgins LJ, MacGillivray C, Gannon J, Lee RT. Local delivery of protease-resistant stromal cell derived factor-1 for stem cell recruitment after myocardial infarction. Circulation. 2007;116:1683-1692. doi: 10.1161/CIRCULATIONAHA.107.718718.
    • (2007) Circulation , vol.116 , pp. 1683-1692
    • Segers, V.F.1    Tokunou, T.2    Higgins, L.J.3    MacGillivray, C.4    Gannon, J.5    Lee, R.T.6
  • 56
    • 38749137749 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart
    • Miller EJ, Li J, Leng L, McDonald C, Atsumi T, Bucala R, Young LH. Macrophage migration inhibitory factor stimulates AMP-activated protein kinase in the ischaemic heart. Nature. 2008;451:578-582. doi: 10.1038/ nature06504.
    • (2008) Nature , vol.451 , pp. 578-582
    • Miller, E.J.1    Li, J.2    Leng, L.3    McDonald, C.4    Atsumi, T.5    Bucala, R.6    Young, L.H.7
  • 57
    • 79952369026 scopus 로고    scopus 로고
    • Macrophage migration inhibitory factor provides cardioprotection during ischemia/reperfusion by reducing oxidative stress
    • Koga K, Kenessey A, Powell SR, Sison CP, Miller EJ, Ojamaa K. Macrophage migration inhibitory factor provides cardioprotection during ischemia/reperfusion by reducing oxidative stress. Antioxid Redox Signal. 2011;14:1191-1202. doi: 10.1089/ars.2010.3163.
    • (2011) Antioxid Redox Signal , vol.14 , pp. 1191-1202
    • Koga, K.1    Kenessey, A.2    Powell, S.R.3    Sison, C.P.4    Miller, E.J.5    Ojamaa, K.6
  • 58
    • 77958086724 scopus 로고    scopus 로고
    • Cardiac functional improvement in rats with myocardial infarction by up-regulating cardiac myosin light chain kinase with neuregulin
    • Gu X, Liu X, Xu D, et al. Cardiac functional improvement in rats with myocardial infarction by up-regulating cardiac myosin light chain kinase with neuregulin. Cardiovasc Res. 2010;88:334-343. doi: 10.1093/cvr/ cvq223.
    • (2010) Cardiovasc Res , vol.88 , pp. 334-343
    • Gu, X.1    Liu, X.2    Xu, D.3
  • 59
    • 84860845011 scopus 로고    scopus 로고
    • Oxidative stress and cardiac hypertrophy: A review
    • Maulik SK, Kumar S. Oxidative stress and cardiac hypertrophy: a review. Toxicol Mech Methods. 2012;22:359-366. doi: 10.3109/ 15376516.2012.666650.
    • (2012) Toxicol Mech Methods , vol.22 , pp. 359-366
    • Maulik, S.K.1    Kumar, S.2
  • 60
    • 0037991449 scopus 로고    scopus 로고
    • Molecular determinants of myocardial hypertrophy and failure: Alternative pathways for beneficial and maladaptive hypertrophy
    • Lips DJ, deWindt LJ, van Kraaij DJ, Doevendans PA. Molecular determinants of myocardial hypertrophy and failure: alternative pathways for beneficial and maladaptive hypertrophy. Eur Heart J. 2003;24:883-896.
    • (2003) Eur Heart J , vol.24 , pp. 883-896
    • Lips, D.J.1    DeWindt, L.J.2    Van Kraaij, D.J.3    Doevendans, P.A.4
  • 61
    • 84929130857 scopus 로고    scopus 로고
    • The winding road to regenerating the human heart
    • Gerbin KA, Murry CE. The winding road to regenerating the human heart. Cardiovasc Pathol. 2015;24:133-140. doi: 10.1016/j.carpath.2015.02.004.
    • (2015) Cardiovasc Pathol , vol.24 , pp. 133-140
    • Gerbin, K.A.1    Murry, C.E.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.