Apoptotic Diminution of Immature Single and Double Positive Thymocyte Subpopulations Contributes to Thymus Involution during Murine Polymicrobial Sepsis

Shock

Volumn 48, Issue 2, 2017, Pages 215-226

  Netzer, Christoph ^a   Knape, Tilo ^b   Kuchler, Laura ^a   Weigert, Andreas ^a   Zacharowski, Kai ^c   Pfeilschifter, Waltraud ^c   Sempowski, Gregory ^d   Parnham, Michael J ^b   Brüne, Bernhard ^a,b   Von Knethen, Andreas ^a,b  

^a GOETHE UNIVERSITY   (Germany)

^b FRAUNHOFER INSTITUTE FOR MOLECULAR BIOLOGY AND APPLIED ECOLOGY IME   (Germany)

^c UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^d DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

CLP; DP; ISP; sepsis; thymocyte depletion

Indexed keywords

BIM PROTEIN; CD3 ANTIGEN; CD4 ANTIGEN; CD45 ANTIGEN; CD69 ANTIGEN; CD8 ANTIGEN; COMPLEMENTARY DNA; DELTA LIKE 1; DELTA LIKE 4; INTERLEUKIN 2 RECEPTOR ALPHA; MESSENGER RNA; NOTCH1 RECEPTOR; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PROTEIN; PROTEIN KINASE B; T LYMPHOCYTE RECEPTOR; THY 1 ANTIGEN; UNCLASSIFIED DRUG; BCL2L11 PROTEIN, MOUSE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CELL ISOLATION; CELL VIABILITY; FLOW CYTOMETRY; MALE; MOUSE; NONHUMAN; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; SEPSIS; SIGNAL TRANSDUCTION; SPLEEN CELL; STROMA CELL; THYMOCYTE; THYMUS; UPREGULATION; ANIMAL; DISEASE MODEL; IMMUNOLOGY; PATHOLOGY;

ANIMALS; APOPTOSIS; BCL-2-LIKE PROTEIN 11; DISEASE MODELS, ANIMAL; MALE; MICE; SEPSIS; THYMOCYTES; THYMUS GLAND;

EID: 85026253112     PISSN: 10732322     EISSN: 15400514     Source Type: Journal    
DOI: 10.1097/SHK.0000000000000842     Document Type: Article

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