A single nucleotide polymorphism in the NCF1 gene leading to reduced oxidative burst is associated with systemic lupus erythematosus

Annals of the Rheumatic Diseases

Volumn 76, Issue 9, 2017, Pages 1607-1613

  Olsson, Lina M ^a   Johansson, Åsa C ^b   Gullstrand, Birgitta ^c   Jönsen, Andreas ^c   Saevarsdottir, Saedis ^d   Rönnblom, Lars ^e   Leonard, Dag ^e   Wetterö, Jonas ^f   Sjöwall, Christopher ^f   Svenungsson, Elisabet ^d   Gunnarsson, Iva ^d   Bengtsson, Anders A ^c   Holmdahl, Rikard ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b LUND UNIVERSITY   (Sweden)

^c LUND UNIVERSITY   (Sweden)

^d KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

^e UPPSALA UNIVERSITY   (Sweden)

^f LINKÖPING UNIVERSITY   (Sweden)

Author keywords

autoimmunity; NADPH oxidase complex; NCF1; reactive oxygen species; SLE

Indexed keywords

INTERFERON; REACTIVE OXYGEN METABOLITE; NEUTROPHIL CYTOSOLIC FACTOR 1; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE;

AGE; ARTICLE; CONTROLLED STUDY; GENE; GENE EXPRESSION; GENE FREQUENCY; GENETIC ASSOCIATION; GENETIC RISK; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; NCF1 GENE; NEUTROPHIL; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PYROSEQUENCING; RESPIRATORY BURST; SINGLE NUCLEOTIDE POLYMORPHISM; SYSTEMIC LUPUS ERYTHEMATOSUS; ADULT; CASE CONTROL STUDY; CAUCASIAN; FEMALE; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; MALE; METABOLISM; SWEDEN;

ADULT; CASE-CONTROL STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LUPUS ERYTHEMATOSUS, SYSTEMIC; MALE; NADPH OXIDASE; NEUTROPHILS; POLYMORPHISM, SINGLE NUCLEOTIDE; REACTIVE OXYGEN SPECIES; RESPIRATORY BURST; SWEDEN;

EID: 85024929994     PISSN: 00034967     EISSN: 14682060     Source Type: Journal    
DOI: 10.1136/annrheumdis-2017-211287     Document Type: Article

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