Systematic evaluation of oligodeoxynucleotide binding and hybridization to modified multi-walled carbon nanotubes

Journal of Nanobiotechnology

Volumn 15, Issue 1, 2017, Pages

  Kaufmann, Anika ^a,d   Hampel, Silke ^b   Rieger, Christiane ^c   Kunhardt, David ^b   Schendel, Darja ^c   Füssel, Susanne ^c   Schwenzer, Bernd ^a   Erdmann, Kati ^c  

^a DRESDEN UNIVERSITY OF TECHNOLOGY   (Germany)

^b IFW DRESDEN   (Germany)

^c UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^d LEIBNIZ INSTITUTE OF POLYMER RESEARCH DRESDEN   (Germany)

Author keywords

Antisense oligodeoxynucleotides; Biocompatibility; Bladder cancer; Carbon nanotubes; Carrier strand; Functionalization; Hybridization; Mucoadhesion; Urothelium

Indexed keywords

BINS; BIOCOMPATIBILITY; CARBON; CARBON NANOTUBES; DISEASES; HYDROPHILICITY; NANOTUBES; NUCLEIC ACIDS; YARN;

ANTISENSE OLIGODEOXYNUCLEOTIDES; BLADDER CANCERS; CARRIER STRAND; FUNCTIONALIZATIONS; HYBRIDIZATION; MUCOADHESION; UROTHELIUM;

MULTIWALLED CARBON NANOTUBES (MWCN);

ANTISENSE OLIGODEOXYNUCLEOTIDE; MULTI WALLED NANOTUBE; ANTISENSE OLIGONUCLEOTIDE; CARBON NANOTUBE; DRUG CARRIER; OLIGODEOXYRIBONUCLEOTIDE;

ADSORPTION KINETICS; ANIMAL CELL; ARTICLE; BINDING AFFINITY; BINDING KINETICS; CELL VIABILITY; CHEMICAL STRUCTURE; CONTROLLED STUDY; COVALENT BOND; FLUORESCENCE ANALYSIS; HYBRIDIZATION; HYDROPHILICITY; MOLECULAR STABILITY; MOUSE; MUCOADHESION; NANOANALYSIS; NONHUMAN; PHYSICAL CHEMISTRY; ADSORPTION; ANIMAL; BLADDER; CELL ADHESION; CELL LINE; CELL SURVIVAL; CHEMISTRY; DRUG EFFECTS; DRUG RELEASE; HUMAN; NUCLEIC ACID HYBRIDIZATION; PHYSIOLOGY; SURFACE PROPERTY; URINE; UROTHELIUM;

ADSORPTION; ANIMALS; CELL ADHESION; CELL LINE; CELL SURVIVAL; DRUG CARRIERS; DRUG LIBERATION; HUMANS; MICE; NANOTUBES, CARBON; NUCLEIC ACID HYBRIDIZATION; OLIGODEOXYRIBONUCLEOTIDES; OLIGONUCLEOTIDES, ANTISENSE; SURFACE PROPERTIES; URINARY BLADDER; UROTHELIUM;

EID: 85024372906     PISSN: None     EISSN: 14773155     Source Type: Journal    
DOI: 10.1186/s12951-017-0288-z     Document Type: Article

References (39)

1. Babjuk M, Burger M, Zigeuner R, Shariat SF, van Rhijn BW, Comperat E, Sylvester RJ, Kaasinen E, Bohle A, Palou Redorta J, Roupret M, European Association of U. EAU guidelines on non-muscle-invasive urothelial carcinoma of the bladder: update 2013. Eur Urol. 2013;64:639-53.
2. Witjes JA, Comperat E, Cowan NC, van der Santis M, Gakis G, Lebret T, Ribal MJ, de Heijden AG, Sherif A, European Association of U. EAU guidelines on muscle-invasive and metastatic bladder cancer: summary of the 2013 guidelines. Eur Urol. 2014;65:778-92.
3. GuhaSarkar S, Banerjee R. Intravesical drug delivery: challenges, current status, opportunities and novel strategies. J Control Release. 2010;148:147-59.
4. Massari F, Santoni M, Ciccarese C, Brunelli M, Conti A, Santini D, Montironi R, Cascinu S, Tortora G. Emerging concepts on drug resistance in bladder cancer: implications for future strategies. Crit Rev Oncol Hematol. 2015;96:81-90.
5. Chandrasekar T, Evans CP. Autophagy and urothelial carcinoma of the bladder: a review. Investig Clin Urol. 2016;57(Suppl 1):S89-97.
6. Bates K, Kostarelos K. Carbon nanotubes as vectors for gene therapy: past achievements, present challenges and future goals. Adv Drug Deliv Rev. 2013;65:2023-33.
7. Kumar S, Rani R, Dilbaghi N, Tankeshwar K, Kim KH. Carbon nanotubes: a novel material for multifaceted applications in human healthcare. Chem Soc Rev. 2017;46:158-96.
8. Caoduro C, Hervouet E, Girard-Thernier C, Gharbi T, Boulahdour H, Delage-Mourroux R, Pudlo M. Carbon nanotubes as gene carriers: focus on internalization pathways related to functionalization and properties. Acta Biomater. 2017;49:36-44.
9. Arlt M, Haase D, Hampel S, Oswald S, Bachmatiuk A, Klingeler R, Schulze R, Ritschel M, Leonhardt A, Fuessel S, Buchner B, Kraemer K, Wirth MP. Delivery of carboplatin by carbon-based nano containers mediates increased cancer cell death. Nanotechnology. 2010;21:335101.
10. Hampel S, Kunze D, Haase D, Kramer K, Rauschenbach M, Ritschel M, Leonhardt A, Thomas J, Oswald S, Hoffmann V, Buchner B. Carbon nanotubes filled with a chemotherapeutic agent: a nanocarrier mediates inhibition of tumor cell growth. Nanomedicine (Lond). 2008;3:175-82.
11. Kaufmann A, Kunhardt D, Cirillo G, Hampel S, Schwenzer B. Functionalized carbon nanotubes as transporters for antisense oligodeoxynucleotides. J Mater Chem B. 2014;2:7000-8.
12. Crinelli R, Carloni E, Menotta M, Giacomini E, Bianchi M, Ambrosi G, Giorgi L, Magnani M. Oxidized ultrashort nanotubes as carbon scaffolds for the construction of cell-penetrating NF-kappaB decoy molecules. ACS Nano. 2010;4:2791-803.
13. Jia N, Lian Q, Shen H, Wang C, Li X, Yang Z. Intracellular delivery of quantum dots tagged antisense oligodeoxynucleotides by functionalized multiwalled carbon nanotubes. Nano Lett. 2007;7:2976-80.
14. Pan B, Cui D, Xu P, Ozkan C, Feng G, Ozkan M, Huang T, Chu B, Li Q, He R, Hu G. Synthesis and characterization of polyamidoamine dendrimer-coated multi-walled carbon nanotubes and their application in gene delivery systems. Nanotechnology. 2009;20:125101.
15. Rieger C, Kunhardt D, Kaufmann A, Schendel D, Huebner D, Erdmann K, Propping S, Wirth MP, Schwenzer B, Fuessel S, Hampel S. Characterization of different carbon nanotubes for the development of a mucoadhesive drug delivery system for intravesical treatment of bladder cancer. Int J Pharm. 2015;479:357-63.
16. Ringel J, Erdmann K, Hampel S, Kraemer K, Maier D, Arlt M, Kunze D, Wirth MP, Fuessel S. Carbon nanofibers and carbon nanotubes sensitize prostate and bladder cancer cells to platinum-based chemotherapeutics. J Biomed Nanotechnol. 2014;10:463-77.
17. Ritschel M, Leonhardt A, Elefant D, Oswald S, Büchner B. Rhenium-catalyzed growth carbon nanotubes. J Phys Chem C. 2007;111:8414-7.
18. Jeong YN, Choi MY, Choi HC. Preparation of Pt- and Pd-decorated CNTs by DCC-activated amidation and investigation of their electrocatalytic activities. Electrochim Acta. 2012;60:78-84.
19. Forster Y, Meye A, Krause S, Schwenzer B. Antisense-mediated VEGF suppression in bladder and breast cancer cells. Cancer Lett. 2004;212:95-103.
20. Karachevtsev MV, Gladchenko GO, Plokhotnichenko AM, Leontiev VS, Karachevtsev VA. Adsorption of biopolymers on SWCNT: ordered poly(rC) and disordered poly(rI). J Phys Chem B. 2013;117:2636-44.
21. Johnston HJ, Hutchison GR, Christensen FM, Peters S, Hankin S, Aschberger K, Stone V. A critical review of the biological mechanisms underlying the in vivo and in vitro toxicity of carbon nanotubes: the contribution of physico-chemical characteristics. Nanotoxicology. 2010;4:207-46.
22. Zhang T, Tang M, Kong L, Li H, Zhang T, Zhang S, Xue Y, Pu Y. Comparison of cytotoxic and inflammatory responses of pristine and functionalized multi-walled carbon nanotubes in RAW 264.7 mouse macrophages. J Hazard Mater. 2012;219-220:203-12.
23. Ursini CL, Maiello R, Ciervo A, Fresegna AM, Buresti G, Superti F, Marchetti M, Iavicoli S, Cavallo D. Evaluation of uptake, cytotoxicity and inflammatory effects in respiratory cells exposed to pristine and -OH and -COOH functionalized multi-wall carbon nanotubes. J Appl Toxicol. 2016;36:394-403.
24. Saxena RK, Williams W, McGee JK, Daniels MJ, Boykin E, Ian Gilmour M. Enhanced in vitro and in vivo toxicity of poly-dispersed acid-functionalized single-wall carbon nanotubes. Nanotoxicology. 2007;1:291-300.
25. Patlolla A, Patlolla B, Tchounwou P. Evaluation of cell viability, DNA damage, and cell death in normal human dermal fibroblast cells induced by functionalized multiwalled carbon nanotube. Mol Cell Biochem. 2010;338:225-32.
26. Muller J, Huaux F, Fonseca A, Nagy JB, Moreau N, Delos M, Raymundo-Pinero E, Beguin F, Kirsch-Volders M, Fenoglio I, Fubini B, Lison D. Structural defects play a major role in the acute lung toxicity of multiwall carbon nanotubes: toxicological aspects. Chem Res Toxicol. 2008;21:1698-705.
27. Karimi M, Solati N, Ghasemi A, Estiar MA, Hashemkhani M, Kiani P, Mohamed E, Saeidi A, Taheri M, Avci P, Aref AR, Amiri M, Baniasadi F, Hamblin MR. Carbon nanotubes part II: a remarkable carrier for drug and gene delivery. Expert Opin Drug Deliv. 2015;12:1089-105.
28. Barthelmes J, Dunnhaupt S, Unterhofer S, Perera G, Schlocker W, Bernkop-Schnurch A. Thiolated particles as effective intravesical drug delivery systems for treatment of bladder-related diseases. Nanomedicine (Lond). 2013;8:65-75.
29. Barthelmes J, Perera G, Hombach J, Dunnhaupt S, Bernkop-Schnurch A. Development of a mucoadhesive nanoparticulate drug delivery system for a targeted drug release in the bladder. Int J Pharm. 2011;416:339-45.
30. Huang C, Neoh KG, Xu L, Kang ET, Chiong E. Polymeric nanoparticles with encapsulated superparamagnetic iron oxide and conjugated cisplatin for potential bladder cancer therapy. Biomacromol. 2012;13:2513-20.
31. Zhang Q, Neoh KG, Xu L, Lu S, Kang ET, Mahendran R, Chiong E. Functionalized mesoporous silica nanoparticles with mucoadhesive and sustained drug release properties for potential bladder cancer therapy. Langmuir. 2014;30:6151-61.
32. Lu S, Xu L, Kang ET, Mahendran R, Chiong E, Neoh KG. Co-delivery of peptide-modified cisplatin and doxorubicin via mucoadhesive nanocapsules for potential synergistic intravesical chemotherapy of non-muscle-invasive bladder cancer. Eur J Pharm Sci. 2016;84:103-15.
33. Mun EA, Williams AC, Khutoryanskiy VV. Adhesion of thiolated silica nanoparticles to urinary bladder mucosa: effects of PEGylation, thiol content and particle size. Int J Pharm. 2016;512:32-8.
34. Storha A, Mun EA, Khutoryanskiy VV. Synthesis of thiolated and acrylated nanoparticles using thiol-ene click chemistry: towards novel mucoadhesive materials for drug delivery. Rsc Adv. 2013;3:12275-9.
35. Denora N, Lopedota A, Perrone M, Laquintana V, Iacobazzi RM, Milella A, Fanizza E, Depalo N, Cutrignelli A, Lopalco A, Franco M. Spray-dried mucoadhesives for intravesical drug delivery using N-acetylcysteine- and glutathione-glycol chitosan conjugates. Acta Biomater. 2016;43:170-84.
36. Cirillo G, Hampel S, Spizzirri UG, Parisi OI, Picci N, Iemma F. Carbon nanotubes hybrid hydrogels in drug delivery: a perspective review. Biomed Res Int. 2014;2014:825017.
37. Nordstrom LJ, Clark CA, Andersen B, Champlin SM, Schwinefus JJ. Effect of ethylene glycol, urea, and N-methylated glycines on DNA thermal stability: the role of DNA base pair composition and hydration. Biochemistry. 2006;45:9604-14.
38. Fuessel S, Kueppers B, Ning S, Kotzsch M, Kraemer K, Schmidt U, Meye A, Wirth MP. Systematic in vitro evaluation of survivin directed antisense oligodeoxynucleotides in bladder cancer cells. J Urol. 2004;171:2471-6.
39. Kraemer K, Fuessel S, Schmidt U, Kotzsch M, Schwenzer B, Wirth MP, Meye A. Antisense-mediated hTERT inhibition specifically reduces the growth of human bladder cancer cells. Clin Cancer Res. 2003;9:3794-800.