Gold nanoparticle-based miR155 antagonist macrophage delivery restores the cardiac function in ovariectomized diabetic mouse model

International Journal of Nanomedicine

Volumn 12, Issue , 2017, Pages 4963-4979

  Jia, Hengming ^a,b   Chen, Hui ^c   Wei, Mengying ^b   Chen, Xiangjie ^d   Zhang, Yajun ^c   Cao, Liang ^a   Yuan, Ping ^a   Wang, Fangyuan ^a   Yang, Guodong ^b   Ma, Jing ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^c FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^d SOUTHEAST UNIVERSITY   (China)

Author keywords

Cardiac function; Gold nanoparticle; Macrophage; MiR155; Ovariectomized diabetic mouse model; Targeted delivery

Indexed keywords

GOLD NANOPARTICLE; INTERLEUKIN 10; INTERLEUKIN 1BETA; MICRORNA 155; GOLD; MICRORNA; MIRN155 MICRORNA, MOUSE; NANOPARTICLE;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CARDIOMYOPATHY; CARDIOVASCULAR RESPONSE; CELL SIZE; CONTROLLED STUDY; FEMALE; GENE DELIVERY SYSTEM; GENE EXPRESSION; HEART FUNCTION; HEART LEFT VENTRICLE EJECTION FRACTION; HEART MUSCLE FIBROSIS; HEART VENTRICLE HYPERTROPHY; MACROPHAGE; MOUSE; NONHUMAN; PARTICLE SIZE; PHAGOCYTOSIS; PROTEIN EXPRESSION; RNA SEQUENCE; UPREGULATION; ANIMAL; ANTAGONISTS AND INHIBITORS; C57BL MOUSE; CARDIAC MUSCLE; CHEMISTRY; DIABETIC CARDIOMYOPATHIES; DRUG DELIVERY SYSTEM; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; FIBROSIS; GENETICS; MYOCARDITIS; OVARIECTOMY; PATHOLOGY; PATHOPHYSIOLOGY; PROCEDURES;

ANIMALS; APOPTOSIS; DIABETES MELLITUS, EXPERIMENTAL; DIABETIC CARDIOMYOPATHIES; DRUG DELIVERY SYSTEMS; FEMALE; FIBROSIS; GOLD; MACROPHAGES; MICE, INBRED C57BL; MICRORNAS; MYOCARDITIS; MYOCARDIUM; NANOPARTICLES; OVARIECTOMY;

EID: 85024104454     PISSN: 11769114     EISSN: 11782013     Source Type: Journal    
DOI: 10.2147/IJN.S138400     Document Type: Article

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