Concordance of genomic alterations by next-generation sequencing in tumor tissue versus circulating tumor DNA in breast cancer

Molecular Cancer Therapeutics

Volumn 16, Issue 7, 2017, Pages 1412-1420

  Chae, Young Kwang ^a   Davis, Andrew A ^a   Jain, Sarika ^a   Santa Maria, Cesar ^a   Flaum, Lisa ^a   Beaubier, Nike ^a   Platanias, Leonidas C ^a,b   Gradishar, William ^a   Giles, Francis J ^a   Cristofanilli, Massimo ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

^b JESSE BROWN VA MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; CHLOROPLAST DNA; CIRCULATING TUMOR DNA; DNA; EPIDERMAL GROWTH FACTOR RECEPTOR 2; PIK3CA PROTEIN; PROTEIN; PROTEIN P53; UNCLASSIFIED DRUG; BRCA1 PROTEIN, HUMAN; BRCA2 PROTEIN, HUMAN; ERBB2 PROTEIN, HUMAN; PHOSPHATIDYLINOSITOL 4,5 BISPHOSPHATE 3 KINASE; PIK3CA PROTEIN, HUMAN; TP53 PROTEIN, HUMAN; TUMOR MARKER;

ADULT; ARTICLE; BREAST CANCER; CANCER DIAGNOSIS; CANCER PROGNOSIS; CANCER TISSUE; CONTROLLED STUDY; DNA CONTAMINATION; FEMALE; GENE FREQUENCY; GENE MUTATION; GERMLINE MUTATION; HUMAN; HUMAN TISSUE; MALE; MEDICAL RECORD REVIEW; NEXT GENERATION SEQUENCING; OVERLAPPING GENE; PREDICTIVE VALUE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; SENSITIVITY AND SPECIFICITY; BIOPSY; BLOOD; BREAST TUMOR; GENETICS; GENOMICS; HIGH THROUGHPUT SEQUENCING; HUMAN GENOME; MIDDLE AGED; MUTATION; PATHOLOGY; TUMOR CELL LINE;

BIOMARKERS, TUMOR; BIOPSY; BRCA1 PROTEIN; BRCA2 PROTEIN; BREAST NEOPLASMS; CELL LINE, TUMOR; CIRCULATING TUMOR DNA; CLASS I PHOSPHATIDYLINOSITOL 3-KINASES; FEMALE; GENOME, HUMAN; GENOMICS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MALE; MIDDLE AGED; MUTATION; RECEPTOR, ERBB-2; TUMOR SUPPRESSOR PROTEIN P53;

EID: 85023764675     PISSN: 15357163     EISSN: 15388514     Source Type: Journal    
DOI: 10.1158/1535-7163.MCT-17-0061     Document Type: Article

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