-
1
-
-
83655193529
-
The role of the kidneys in glucose homeostasis: a new path towards normalizing glycaemia
-
DeFronzo RA, Davidson JA, Del Prato S. The role of the kidneys in glucose homeostasis: a new path towards normalizing glycaemia. Diabetes Obes Metab. 2012;14:5-14.
-
(2012)
Diabetes Obes Metab
, vol.14
, pp. 5-14
-
-
DeFronzo, R.A.1
Davidson, J.A.2
Del Prato, S.3
-
2
-
-
80052362968
-
Role of sodium-glucose cotransporter 2 (SGLT 2) inhibitors in the treatment of type 2 diabetes
-
Abdul-Ghani MA, Norton L, Defronzo RA. Role of sodium-glucose cotransporter 2 (SGLT 2) inhibitors in the treatment of type 2 diabetes. Endocr Rev. 2011;32:515-531.
-
(2011)
Endocr Rev
, vol.32
, pp. 515-531
-
-
Abdul-Ghani, M.A.1
Norton, L.2
Defronzo, R.A.3
-
3
-
-
1242272759
-
The sodium/glucose cotransport family SLC5
-
Wright EM, Turk E. The sodium/glucose cotransport family SLC5. Pflugers Arch. 2004;447:510-518.
-
(2004)
Pflugers Arch
, vol.447
, pp. 510-518
-
-
Wright, E.M.1
Turk, E.2
-
5
-
-
0034997336
-
Renal Na(+)-glucose cotransporters
-
Wright EM. Renal Na(+)-glucose cotransporters. Am J Physiol Renal Physiol. 2001;280:F10-F18.
-
(2001)
Am J Physiol Renal Physiol
, vol.280
, pp. F10-F18
-
-
Wright, E.M.1
-
6
-
-
0028321936
-
Structure of the human Na+/glucose cotransporter gene SGLT1
-
Turk E, Martin MG, Wright EM. Structure of the human Na+/glucose cotransporter gene SGLT1. J Biol Chem. 1994;269:15204-15209.
-
(1994)
J Biol Chem
, vol.269
, pp. 15204-15209
-
-
Turk, E.1
Martin, M.G.2
Wright, E.M.3
-
7
-
-
84891865819
-
Characterization of renal glucose reabsorption in response to dapagliflozin in healthy subjects and subjects with type 2 diabetes
-
DeFronzo RA, Hompesch M, Kasichayanula S, et al. Characterization of renal glucose reabsorption in response to dapagliflozin in healthy subjects and subjects with type 2 diabetes. Diabetes Care. 2013;36:3169-3176.
-
(2013)
Diabetes Care
, vol.36
, pp. 3169-3176
-
-
DeFronzo, R.A.1
Hompesch, M.2
Kasichayanula, S.3
-
8
-
-
64749094872
-
Effect of diabetes and insulin of the maximum capacity of the renal tubules to reabsorb glucose
-
Farber SJ, Berger EY, Earle DP. Effect of diabetes and insulin of the maximum capacity of the renal tubules to reabsorb glucose. J Clin Invest. 1951;30:125-129.
-
(1951)
J Clin Invest
, vol.30
, pp. 125-129
-
-
Farber, S.J.1
Berger, E.Y.2
Earle, D.P.3
-
9
-
-
0015122757
-
Maximum tubular reabsorption capacity for glucose and renal hemodynamcis during rapid hypertonic glucose infusion in normal and diabetic subjects
-
Mogensen CE. Maximum tubular reabsorption capacity for glucose and renal hemodynamcis during rapid hypertonic glucose infusion in normal and diabetic subjects. Scand J Clin Lab Invest. 1971;28:101-109.
-
(1971)
Scand J Clin Lab Invest
, vol.28
, pp. 101-109
-
-
Mogensen, C.E.1
-
10
-
-
84865479822
-
Why do SGLT2 inhibitors inhibit only 30–50% of renal glucose reabsorption in humans?
-
Liu JJ, Lee T, DeFronzo RA. Why do SGLT2 inhibitors inhibit only 30–50% of renal glucose reabsorption in humans? Diabetes. 2012;61:2199-2204.
-
(2012)
Diabetes
, vol.61
, pp. 2199-2204
-
-
Liu, J.J.1
Lee, T.2
DeFronzo, R.A.3
-
11
-
-
38549182041
-
Na(+) -glucose transporter-2 messenger ribonucleic acid expression in kidney of diabetic rats correlates with glycemic levels: involvement of hepatocyte nuclear factor-1alpha expression and activity
-
Freitas HS, Anhe GF, Melo KF, et al. Na(+) -glucose transporter-2 messenger ribonucleic acid expression in kidney of diabetic rats correlates with glycemic levels: involvement of hepatocyte nuclear factor-1alpha expression and activity. Endocrinology. 2008;149:717-724.
-
(2008)
Endocrinology
, vol.149
, pp. 717-724
-
-
Freitas, H.S.1
Anhe, G.F.2
Melo, K.F.3
-
12
-
-
84971330679
-
Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice
-
Gallo LA, Ward MS, Fotheringham AK, et al. Once daily administration of the SGLT2 inhibitor, empagliflozin, attenuates markers of renal fibrosis without improving albuminuria in diabetic db/db mice. Sci Rep. 2016;6:26428.
-
(2016)
Sci Rep
, vol.6
, pp. 26428
-
-
Gallo, L.A.1
Ward, M.S.2
Fotheringham, A.K.3
-
13
-
-
33644688031
-
Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes
-
Rahmoune H, Thompson PW, Ward JM, Smith CD, Hong G, Brown J. Glucose transporters in human renal proximal tubular cells isolated from the urine of patients with non-insulin-dependent diabetes. Diabetes. 2005;54:3427-3434.
-
(2005)
Diabetes
, vol.54
, pp. 3427-3434
-
-
Rahmoune, H.1
Thompson, P.W.2
Ward, J.M.3
Smith, C.D.4
Hong, G.5
Brown, J.6
-
14
-
-
84857074203
-
Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation pronouncedly underestimates glomerular filtration rate in type 2 diabetes
-
Silveiro SP, Araujo GN, Ferreira MN, Souza FD, Yamaguchi HM, Camargo EG. Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation pronouncedly underestimates glomerular filtration rate in type 2 diabetes. Diabetes Care. 2011;34:2353-2355.
-
(2011)
Diabetes Care
, vol.34
, pp. 2353-2355
-
-
Silveiro, S.P.1
Araujo, G.N.2
Ferreira, M.N.3
Souza, F.D.4
Yamaguchi, H.M.5
Camargo, E.G.6
-
15
-
-
84924320472
-
The mechanisms of genome-wide target gene regulation by TCF7L2 in liver cells
-
Norton L, Chen X, Fourcaudot M, Acharya NK, DeFronzo RA, Heikkinen S. The mechanisms of genome-wide target gene regulation by TCF7L2 in liver cells. Nucleic Acids Res. 2014;42:13646-13661.
-
(2014)
Nucleic Acids Res
, vol.42
, pp. 13646-13661
-
-
Norton, L.1
Chen, X.2
Fourcaudot, M.3
Acharya, N.K.4
DeFronzo, R.A.5
Heikkinen, S.6
-
16
-
-
0037129827
-
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
-
Vandesompele J, De Preter K, Pattyn F, et al. Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes. Genome Biol. 2002;3:RESEARCH0034.
-
(2002)
Genome Biol
, vol.3
-
-
Vandesompele, J.1
De Preter, K.2
Pattyn, F.3
-
17
-
-
0002874570
-
Gene expression of epithelial glucose transporters: the role of diabetes mellitus
-
Dominguez JH, Song B, Maianu L, Garvey WT, Qulali M. Gene expression of epithelial glucose transporters: the role of diabetes mellitus. J Am Soc Nephrol. 1994;5:S29-S36.
-
(1994)
J Am Soc Nephrol
, vol.5
, pp. S29-S36
-
-
Dominguez, J.H.1
Song, B.2
Maianu, L.3
Garvey, W.T.4
Qulali, M.5
-
18
-
-
0030851867
-
Overexpression of GLUT2 gene in renal proximal tubules of diabetic Zucker rats
-
Kamran M, Peterson RG, Dominguez JH. Overexpression of GLUT2 gene in renal proximal tubules of diabetic Zucker rats. J Am Soc Nephrol. 1997;8:943-948.
-
(1997)
J Am Soc Nephrol
, vol.8
, pp. 943-948
-
-
Kamran, M.1
Peterson, R.G.2
Dominguez, J.H.3
-
19
-
-
85019963940
-
SGLT2 and SGLT1 renal expression in patients with type 2 diabetes
-
Solini A, Rossi C, Mazzanti CM, Proietti A, Koepsell H, Ferrannini E. SGLT2 and SGLT1 renal expression in patients with type 2 diabetes. Diabetes Obes Metab. 2017. https://doi.org/10.1111/dom.12970.
-
(2017)
Diabetes Obes Metab
-
-
Solini, A.1
Rossi, C.2
Mazzanti, C.M.3
Proietti, A.4
Koepsell, H.5
Ferrannini, E.6
-
20
-
-
85016626296
-
SGLT2 Protein expression is increased in human diabetic nephropathy: SGLT2 protein inhibition decreases renal lipid accumulation, inflammation, and the development of nephropathy in diabetic mice
-
Wang XX, Levi J, Luo Y, et al. SGLT2 Protein expression is increased in human diabetic nephropathy: SGLT2 protein inhibition decreases renal lipid accumulation, inflammation, and the development of nephropathy in diabetic mice. J Biol Chem. 2017;292:5335-5348.
-
(2017)
J Biol Chem
, vol.292
, pp. 5335-5348
-
-
Wang, X.X.1
Levi, J.2
Luo, Y.3
-
21
-
-
84937763347
-
Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion
-
Bonner C, Kerr-Conte J, Gmyr V, et al. Inhibition of the glucose transporter SGLT2 with dapagliflozin in pancreatic alpha cells triggers glucagon secretion. Nat Med. 2015;21:512-517.
-
(2015)
Nat Med
, vol.21
, pp. 512-517
-
-
Bonner, C.1
Kerr-Conte, J.2
Gmyr, V.3
-
22
-
-
77951667132
-
Rapid upregulation of sodium-glucose transporter SGLT1 in response to intestinal sweet taste stimulation
-
Stearns AT, Balakrishnan A, Rhoads DB, Tavakkolizadeh A. Rapid upregulation of sodium-glucose transporter SGLT1 in response to intestinal sweet taste stimulation. Ann Surg. 2010;251:865-871.
-
(2010)
Ann Surg
, vol.251
, pp. 865-871
-
-
Stearns, A.T.1
Balakrishnan, A.2
Rhoads, D.B.3
Tavakkolizadeh, A.4
-
23
-
-
84891534541
-
Novel hypothesis to explain why SGLT2 inhibitors inhibit only 30–50% of filtered glucose load in humans
-
Abdul-Ghani MA, DeFronzo RA, Norton L. Novel hypothesis to explain why SGLT2 inhibitors inhibit only 30–50% of filtered glucose load in humans. Diabetes. 2013;62:3324-3328.
-
(2013)
Diabetes
, vol.62
, pp. 3324-3328
-
-
Abdul-Ghani, M.A.1
DeFronzo, R.A.2
Norton, L.3
-
24
-
-
79956331954
-
Canagliflozin, a novel inhibitor of sodium glucose co-transporter 2, dose dependently reduces calculated renal threshold for glucose excretion and increases urinary glucose excretion in healthy subjects
-
Sha S, Devineni D, Ghosh A, et al. Canagliflozin, a novel inhibitor of sodium glucose co-transporter 2, dose dependently reduces calculated renal threshold for glucose excretion and increases urinary glucose excretion in healthy subjects. Diabetes Obes Metab. 2011;13:669-672.
-
(2011)
Diabetes Obes Metab
, vol.13
, pp. 669-672
-
-
Sha, S.1
Devineni, D.2
Ghosh, A.3
-
25
-
-
84905238756
-
The SGLT2 inhibitor empagliflozin ameliorates early features of diabetic nephropathy in BTBR ob/ob type 2 diabetic mice with and without hypertension
-
Gembardt F, Bartaun C, Jarzebska N, et al. The SGLT2 inhibitor empagliflozin ameliorates early features of diabetic nephropathy in BTBR ob/ob type 2 diabetic mice with and without hypertension. Am J Physiol Renal Physiol. 2014;307:F317-F325.
-
(2014)
Am J Physiol Renal Physiol
, vol.307
, pp. F317-F325
-
-
Gembardt, F.1
Bartaun, C.2
Jarzebska, N.3
-
26
-
-
84892588641
-
SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice
-
Vallon V, Gerasimova M, Rose MA, et al. SGLT2 inhibitor empagliflozin reduces renal growth and albuminuria in proportion to hyperglycemia and prevents glomerular hyperfiltration in diabetic Akita mice. Am J Physiol Renal Physiol. 2014;306:F194-F204.
-
(2014)
Am J Physiol Renal Physiol
, vol.306
, pp. F194-F204
-
-
Vallon, V.1
Gerasimova, M.2
Rose, M.A.3
-
27
-
-
0035879385
-
Changes in sodium or glucose filtration rate modulate expression of glucose transporters in renal proximal tubular cells of rat
-
Vestri S, Okamoto MM, de Freitas HS, et al. Changes in sodium or glucose filtration rate modulate expression of glucose transporters in renal proximal tubular cells of rat. J Membr Biol. 2001;182:105-112.
-
(2001)
J Membr Biol
, vol.182
, pp. 105-112
-
-
Vestri, S.1
Okamoto, M.M.2
de Freitas, H.S.3
-
28
-
-
36248931071
-
Effect of long-term type 1 diabetes on renal sodium and water transporters in rats
-
Vidotti DB, Arnoni CP, Maquigussa E, Boim MA. Effect of long-term type 1 diabetes on renal sodium and water transporters in rats. Am J Nephrol. 2008;28:107-114.
-
(2008)
Am J Nephrol
, vol.28
, pp. 107-114
-
-
Vidotti, D.B.1
Arnoni, C.P.2
Maquigussa, E.3
Boim, M.A.4
|