Rapid upregulation of sodium-glucose transporter sglt1 in response to intestinal sweet taste stimulation

Annals of Surgery

Volumn 251, Issue 5, 2010, Pages 865-871

  Stearns, Adam T ^a,b,c   Balakrishnan, Anita ^a,b,d   Rhoads, David B ^b,e   Tavakkolizadeh, Ali ^a,b  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF OXFORD   (United Kingdom)

^d UNIVERSITY OF LIVERPOOL   (United Kingdom)

^e MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAPSAICIN; FRUCTOSE; GLUCOSE; MANNITOL; ONDANSETRON; SACCHARIN; SEROTONIN 3 RECEPTOR; SODIUM GLUCOSE COTRANSPORTER 1; WATER;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DIET; DUODENUM INTUBATION; JEJUNUM MUCOSA; NONHUMAN; NUTRIENT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FOLDING; RAT; SWEETNESS; TOPOGRAPHY; UPREGULATION; WESTERN BLOTTING;

ANIMALS; CAPSAICIN; DIETARY SUCROSE; DUODENUM; GLUCOSE; INTESTINE, SMALL; JEJUNUM; MALE; MANNITOL; ONDANSETRON; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; SODIUM-GLUCOSE TRANSPORTER 1; SUCROSE; SWEETENING AGENTS; UP-REGULATION;

EID: 77951667132     PISSN: 00034932     EISSN: 15281140     Source Type: Journal    
DOI: 10.1097/SLA.0b013e3181d96e1f     Document Type: Article

References (54)

1. American Diabetes Association. Economic costs of diabetes in the U.S. in 2007. Diabetes Care. 2008;31:596-615.
2. Runge CF. Economic consequences of the obese. Diabetes. 2007;56:2668-2672.
3. Buchwald H, Avidor Y, Braunwald E, et al. Bariatric surgery: a systematic review and meta-analysis. JAMA. 2004;292:1724-1737.
4. Morton AP, Hanson PJ. Monosaccharide transport by the small intestine of lean and genetically obese (ob/ob) mice. Q J Exp Physiol. 1984;69:117-126.
5. Bihler I, Freund N. Sugar transport in the small intestine of obese hyperglycemic, fed and fasted mice. Diabetologia. 1975;11:387-393.
6. Ferraris RP, Vinnakota RR. Intestinal nutrient transport in genetically obese mice. Am J Clin Nutr. 1995;62:540-546.
7. Dyer J, Garner A, Wood IS, et al. Changes in the levels of intestinal Na+/glucose co-transporter (SGLT1) in experimental diabetes. Biochem Soc Trans. 1997;25:479S.
8. Burant CF, Flink S, DePaoli AM, et al. Small intestine hexose transport in experimental diabetes. Increased transporter mRNA and protein expression in enterocytes. J Clin Invest. 1994;93:578-585.
9. Fedorak RN, Cheeseman CI, Thomson AB, et al. Altered glucose carrier expression: mechanism of intestinal adaptation during streptozocin-induced diabetes in rats. Am J Physiol. 1991;261(4 pt 1):G585-G591.
10. Dyer J, Wood IS, Palejwala A, et al. Expression of monosaccharide transporters in intestine of diabetic humans. Am J Physiol Gastrointest Liver Physiol. 2002;282:G241-G248.
11. Osswald C, Baumgarten K, Stumpel F, et al. Mice without the regulator gene Rsc1A1 exhibit increased Na +-D-glucose cotransport in small intestine and develop obesity. Mol Cell Biol. 2005;25:78-87.
12. Johnston KL, Clifford MN, Morgan LM. Possible role for apple juice phenolic, compounds in the acute modification of glucose tolerance and gastrointestinal hormone secretion in humans. J Sci Food Agric. 2002;82: 1800-1805.
13. Rossetti L, Smith D, Shulman GI, et al. Correction of hyperglycemia with phlorizin normalizes tissue sensitivity to insulin in diabetic rats. J Clin Invest. 1987;79:1510-1515.
14. Kahn BB, Shulman GI, Defronzo RA, et al. Normalization of blood-glucose in diabetic rats with phlorizin treatment reverses insulin-resistant glucose-transport in adipose-cells without restoring glucose transporter gene-expression. J Clin Invest. 1991;87:561-570.
15. Solberg DH, Diamond JM. Comparison of different dietary sugars as inducers of intestinal sugar transporters. Am J Physiol. 1987;252(4 pt 1):G574-G584.
16. Ferraris RP, Diamond J. Regulation of intestinal sugar transport. Physiol Rev. 1997;77:257-302.
17. Ferraris RP, Diamond J. Crypt-villus site of glucose transporter induction by dietary carbohydrate in mouse intestine. Am J Physiol. 1992;262(6 pt 1): G1069-G1073.
18. Karasov WH, Pond RS III, Solberg DH, et al. Regulation of proline and glucose transport in mouse intestine by dietary substrate levels. Proc Natl Acad Sci USA. 1983;80:7674-7677.
19. Sutton JD. Carbohydrate digestion and glucose supply in the gut of the ruminant. Proc Nutr Soc. 1971;30:243-248.
20. Dyer J, Vayro S, King TP, et al. Glucose sensing in the intestinal epithelium. Eur J Biochem. 2003;270:3377-3388.
21. Young RL, Sutherland K, Pezos N, et al. Expression of taste molecules in the upper gastrointestinal tract in humans with and without type 2 diabetes. Gut. 2009;58:337-346.
22. Bezencon C, le Coutre J, Damak S. Taste-signaling proteins are coexpressed in solitary intestinal epithelial cells. Chem Senses. 2007;32:41-49.
23. Margolskee RF, Dyer J, Kokrashvili Z, et al. T1R3 and gustducin in gut sense sugars to regulate expression of Na +-glucose cotransporter 1. Proc Natl Acad Sci USA. 2007;104:15075-15080.
24. Bates SL, Sharkey KA, Meddings JB. Vagal involvement in dietary regulation of nutrient transport. Am J Physiol. 1998;274(3 pt 1):G552-G560.
25. Stearns AT, Balakrishnan A, Rounds J, et al. Capsaicin-sensitive vagal afferents modulate posttranscriptional regulation of the rat Na+/glucose cotransporter SGLT1. Am J Physiol Gastrointest Liver Physiol. 2008;294: G1078-G1083.
26. Stearns AT, Balakrishnan A, Rhoads DB, et al. Diurnal rhythmicity in the transcription of jejunal drug transporters. J Pharmacol Sci. 2008;108:144-148.
27. Stearns AT, Balakrishnan A, Rhoads DB, et al. Diurnal expression of the rat intestinal sodium-glucose cotransporter 1 (SGLT1) is independent of local luminal factors. Surgery. 2009;145:294-302.
28. Nelson G, Hoon MA, Chandrashekar J, et al. Mammalian sweet taste receptors. Cell. 2001;106:381-390.
29. Chen XM, O'Hara SP, Huang BQ, et al. Localized glucose and water influx facilitates Cryptosporidium parvum cellular invasion by means of modulation of host-cell membrane protrusion. Proc Natl Acad Sci USA. 2005;102:6338-6343.
30. Kellett GL. The facilitated component of intestinal glucose absorption. J Physiol. 2001;531(pt 3):585-595.
31. Pappenheimer JR. Scaling of dimensions of small intestines in non-ruminant eutherian mammals and its significance for absorptive mechanisms. Comp Biochem Physiol A Mol Integr Physiol. 1998;121:45-58.
32. Lane JS, Whang EE, Rigberg DA, et al. Paracellular glucose transport plays a minor role in the unanesthetized dog. Am J Physiol. 1999;276(3 pt 1):G789-G794.
33. Shirazi-Beechey SP. Intestinal sodium-dependent D-glucose co-transporter: dietary regulation. Proc Nutr Soc. 1996;55(1B):167-178.
34. Shirazi-Beechey SP, Hirayama BA, Wang Y, et al. Ontogenic development of lamb intestinal sodium-glucose co-transporter is regulated by diet. J Physiol. 1991;437:699-708.
35. Dyer J, Barker PJ, Shirazi-Beechey SP. Nutrient regulation of the intestinal Na+/glucose co-transporter (SGLT1) gene expression. Biochem Biophys Res Commun. 1997;230:624-629. (Pubitemid 27225587)
36. Lescale-Matys L, Dyer J, Scott D, et al. Regulation of the ovine intestinal Na+/glucose co-transporter (SGLT1) is dissociated from mRNA abundance. Biochem J. 1993;291(pt 2):435-440.
37. Bastidas JA, Orandle MS, Zinner MJ, et al. Small-bowel origin of the signal for meal-induced jejunal absorption. Surgery. 1990;108:376-383.
38. Sarr MG, Kelly KA, Phillips SF. Canine jejunal absorption and transit during interdigestive and digestive motor states. Am J Physiol. 1980;239:G167-G172.
39. Yeo CJ, Bastidas JA, Schmieg RE Jr, et al. Meal-stimulated absorption of water and electrolytes in canine jejunum. Am J Physiol. 1990;259(3 pt 1):G402-G409.
40. Hines OJ, Whang EE, Bilchik AJ, et al. Role of Na +-glucose cotransport in jejunal meal-induced absorption. Dig Dis Sci. 2000;45:1-6.
41. Treesukosol Y, Blonde GD, Spector AC. T1R2 and T1R3 subunits are individually unnecessary for normal affective licking responses to polycose: implications for saccharide taste receptors in mice. Am J Physiol Regul Integr Comp Physiol. 2009;296:R855-R865.
42. Hofer D, Puschel B, Drenckhahn D. Taste receptor-like cells in the rat gut identified by expression of alpha-gustducin Proc Natl Acad Sci USA. 1996;93:6631-6634.
43. Kellett GL, Helliwell PA. The diffusive component of intestinal glucose absorption is mediated by the glucose-induced recruitment of GLUT2 to the brush-border membrane. Biochem J. 2000;350(pt 1):155-162.
44. Mace OJ, Affleck J, Patel N, et al. Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2. J Physiol. 2007;582: 379-392.
45. Mace OJ, Lister N, Morgan E, et al. An energy supply network of nutrient absorption coordinated by calcium and T1R taste receptors in rat small intestine. J Physiol. 2009;587(pt 1):195-210.
46. Freeman SL, Bohan D, Darcel N, et al. Luminal glucose sensing in the rat intestine has characteristics of a sodium-glucose cotransporter. Am J Physiol Gastrointest Liver Physiol. 2006;291:G439-G445.
47. Rubino F, Forgione A, Cummings DE, et al. The mechanism of diabetes control after gastrointestinal bypass surgery reveals a role of the proximal small intestine in the pathophysiology of type 2 diabetes. Ann Surg. 2006; 244:741-749.
48. Anthone GJ, Wang BH, Zinner MJ, et al. Meal-induced jejunal absorption requires intact neural pathways. Am J Surg. 1992;163:150-156.
49. Anthone GJ, Bastidas JA, Zinner MJ, et al. Meal-stimulated canine jejunal ionic absorption. Influence of mucosal neural blockade. Dig Dis Sci. 1994; 39:75-82.
50. Bastidas JA, Yeo CJ, Schmieg RE Jr, et al. Endogenous opiates in the mediation of early meal-induced jejunal absorption of water and electrolytes. Am J Surg. 1989;157:27-32.
51. McFadden DW, Jaffe BM, Ferrara A, et al. Jejunal absorptive response to a test meal and its modification by cholinergic and calcium-channel blockade in the awake dog. Surg Forum. 1984;35:174-176.
52. Raybould HE, Glatzle J, Robin C, et al. Expression of 5-HT3 receptors by extrinsic duodenal afferents contribute to intestinal inhibition of gastric emptying. Am J Physiol Gastrointest Liver Physiol. 2003;284:G367-G372.
53. Sharp JW, Dulake M, Vincent KM, et al. Intestinal glucose-induced phos-phorylation of calcium-calmodulin kinase if (CaMKII) in 5-HT-secreting enterochromaffin cells, myenteric neurons and vagal afferents in the rat. Gastroenterology. 2008;134:A395.
54. Sutherland K, Young RL, Cooper NJ, et al. Phenotypic characterization of taste cells of the mouse small intestine. Am J Physiol Gastrointest Liver Physiol. 2007;292:G1420-G1428.