African ancestry-specific alleles and kidney disease risk in hispanics/latinos

Journal of the American Society of Nephrology

Volumn 28, Issue 3, 2017, Pages 915-922

  Kramer, Holly J ^a,b   Stilp, Adrienne M ^c   Laurie, Cathy C ^c   Reiner, Alex P ^d   Lash, James ^e,f   Daviglus, Martha L ^f   Rosas, Sylvia E ^g   Ricardo, Ana C ^e,f   Tayo, Bamidele O ^a   Flessner, Michael F ^h   Kerr, Kathleen F ^c   Peralta, Carmen ⁱ   Durazo Arvizu, Ramon ^h   Conomos, Matt ^a   Thornton, Timothy ^c   Rotter, Jerome ^c   Taylor, Kent D ⁱ   Cai, Jainwen ^j   Eckfeldt, John ^k   Chen, Han ^l   Papanicolau, George ^c   Franceschini, Nora ^m   more..

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b Department of Biostatistics ^*  (United States)

^c UNIVERSITY OF WASHINGTON   (United States)

^d Division of Nephrology   (United States)

^e UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^f BETH ISRAEL DEACONESS MEDICAL CENTER   (United States)

^g NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES   (United States)

^h UNIVERSITY OF CALIFORNIA   (United States)

ⁱ HARBOR UCLA MEDICAL CENTER   (United States)

^j Department of Biostatistics   (United States)

^k University of North Carolina at Chapel Hill   (United States)

^l UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

^m NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

ALBUMIN; CREATININE; HEMOGLOBIN BETA CHAIN;

ADULT; AFRICAN; ALLELE; ANCESTRY GROUP; APOL1 GENE; ARTICLE; CARIBBEAN (PERSON); CONTROLLED STUDY; FEMALE; GENE; GENE FREQUENCY; GENETIC RISK; GENETIC VARIABILITY; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HISPANIC; HUMAN; KIDNEY DISEASE; MAJOR CLINICAL STUDY; MALE; MICROALBUMINURIA; MIDDLE AGED; PRIORITY JOURNAL; RISK ASSESSMENT; SICKLE CELL TRAIT; SINGLE NUCLEOTIDE POLYMORPHISM; BLACK PERSON; GENETICS; RENAL INSUFFICIENCY, CHRONIC; RISK FACTOR;

AFRICAN CONTINENTAL ANCESTRY GROUP; ALLELES; FEMALE; GENOME-WIDE ASSOCIATION STUDY; HISPANIC AMERICANS; HUMANS; MALE; MIDDLE AGED; RENAL INSUFFICIENCY, CHRONIC; RISK FACTORS;

EID: 85021851183     PISSN: 10466673     EISSN: 15333450     Source Type: Journal    
DOI: 10.1681/ASN.2016030357     Document Type: Article

References (41)

1. United States Census Bureau: 2010 U.S. census. Available at: Www.census.gov. Accessed October 1, 2015.
2. Peralta CA, Shlipak MG, Fan D, Ordoñez J, Lash JP, Chertow GM, Go AS: Risks for end-stage renal disease, cardiovascular events, and death in Hispanic versus non-Hispanic white adults with chronic kidney disease. J Am Soc Nephrol 17: 2892-2899, 2006.
3. Levey AS, Coresh J, Balk E, Kausz AT, Levin A, Steffes MW, Hogg RJ, Perrone RD, Lau J, Eknoyan G; National Kidney Foundation: National Kidney Foundation practice guidelines for chronic kidney disease: Evaluation, classification, and stratification. Ann Intern Med 139: 137- 147, 2003.
4. Jones CA, Francis ME, Eberhardt MS, Chavers B, Coresh J, Engelgau M, Kusek JW, Byrd-Holt D, Narayan KM, Herman WH, Jones CP, Salive M, Agodoa LY: Microalbuminuria in the US population: Third National Health and Nutrition Examination Survey. Am J Kidney Dis 39: 445- 459, 2002.
5. Bryson CL, Ross HJ, Boyko EJ, Young BA: Racial and ethnic variations in albuminuria in the US Third National Health and Nutrition Examination Survey (NHANES III) population: Associations with diabetes and level of CKD. Am J Kidney Dis 48: 720-726, 2006.
6. Kramer H, Jacobs DR Jr, Bild D, Post W, Saad MF, Detrano R, Tracy R, Cooper R, Liu K; The Multi-Ethnic Study of Atherosclerosis: Urine albumin excretion and subclinical cardiovascular disease. Hypertension 46: 38-43, 2005.
7. Pabon-Nau LP, Cohen A, Meigs JB, Grant RW: Hypertension and diabetes prevalence among U.S. Hispanics by country of origin: The National Health Interview Survey 2000-2005. J Gen Intern Med 25: 847-852, 2010.
8. Peralta CA, Li Y, Wassel C, Choudhry S, Palmas W, Seldin MF, Risch N, Siscovick D, Arnett D, Psaty B, Shlipak MG: Differences in albuminuria between Hispanics and whites: An evaluation by genetic ancestry and country of origin: The multi-ethnic study of atherosclerosis. Circ Cardiovasc Genet 3: 240-247, 2010.
9. González Burchard E, Borrell LN, Choudhry S, Naqvi M, Tsai HJ, Rodriguez-Santana JR, Chapela R, Rogers SD, Mei R, Rodriguez-Cintron W, Arena JF, Kittles R, Perez-Stable EJ, Ziv E, Risch N: Latino populations: A unique opportunity for the study of race, genetics, and social environment in epidemiological research. Am J Public Health 95: 2161-2168, 2005.
10. Manichaikul A, Palmas W, Rodriguez CJ, Peralta CA, Divers J, Guo X, Chen WM, Wong Q, Williams K, Kerr KF, Taylor KD, Tsai MY, Goodarzi MO, Sale MM, Diez-Roux AV, Rich SS, Rotter JI, Mychaleckyj JC: Population structure of Hispanics in the United States: The multi-ethnic study of atherosclerosis. PLoS Genet 8: E1002640, 2012.
11. Udler MS, Nadkarni GN, Belbin G, Lotay V, Wyatt C, Gottesman O, Bottinger EP, Kenny EE, Peter I: Effect of genetic African ancestry on eGFR and kidney disease. J Am Soc Nephrol 26: 1682-1692, 2015.
12. Freedman BI, Divers J, Palmer ND: Population ancestry and genetic risk for diabetes and kidney, cardiovascular, and bone disease: modifiable environmental factors may produce the cures. Am J Kidney Dis 62: 1165-1175, 2013.
13. Naik RP, Derebail VK, Grams ME, Franceschini N, Auer PL, Peloso GM, Young BA, Lettre G, Peralta CA, Katz R, Hyacinth HI, Quarells RC, Grove ML, Bick AG, Fontanillas P, Rich SS, Smith JD, Boerwinkle E, Rosamond WD, Ito K, Lanzkron S, Coresh J, Correa A, Sarto GE, Key NS, Jacobs DR, Kathiresan S, Bibbins-Domingo K, Kshirsagar AV, Wilson JG, Reiner AP: Association of sickle cell trait with chronic kidney disease and albuminuria in African Americans. JAMA 312: 2115-2125, 2014.
14. Genovese G, Friedman DJ, Ross MD, Lecordier L, Uzureau P, Freedman BI, Bowden DW, Langefeld CD, Oleksyk TK, Uscinski Knob AL, Bernhardy AJ, Hicks PJ, Nelson GW, Vanhollebeke B, Winkler CA, Kopp JB, Pays E, Pollak MR: Association of trypanolytic ApoL1 variants with kidney disease in African Americans. Science 329: 841-845, 2010.
15. Foster MC, Coresh J, Fornage M, Astor BC, Grams M, Franceschini N, Boerwinkle E, Parekh RS, Kao WH: APOL1 variants associate with increased risk of CKD among African Americans. J Am Soc Nephrol 24: 1484-1491, 2013.
16. Parsa A, Kao WH, Xie D, Astor BC, LiM, Hsu CY, Feldman HI, Parekh RS, Kusek JW, Greene TH, Fink JC, Anderson AH, Choi MJ, Wright JT Jr, Lash JP, Freedman BI, Ojo A, Winkler CA, Raj DS, Kopp JB, He J, Jensvold NG, Tao K, Lipkowitz MS, Appel LJ; AASK Study Investigators; CRIC Study Investigators: APOL1 risk variants, race, and progression of chronic kidney disease. N Engl J Med 369: 2183-2196, 2013.
17. Kopp JB, Nelson GW, Sampath K, Johnson RC, Genovese G, An P, Friedman D, Briggs W, Dart R, Korbet S, Mokrzycki MH, Kimmel PL, Limou S, Ahuja TS, Berns JS, Fryc J, Simon EE, Smith MC, Trachtman H, Michel DM, Schelling JR, Vlahov D, Pollak M, Winkler CA: APOL1 genetic variants in focal segmental glomerulosclerosis and HIV-Associated nephropathy. J Am Soc Nephrol 22: 2129-2137, 2011.
18. Tzur S, Rosset S, Shemer R, Yudkovsky G, Selig S, Tarekegn A, Bekele E, Bradman N, Wasser WG, Behar DM, Skorecki K: Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene. Hum Genet 128: 345-350, 2010.
19. Guasch A, Navarrete J, Nass K, Zayas CF: Glomerular involvement in adults with sickle cell hemoglobinopathies: Prevalence and clinical correlates of progressive renal failure. J Am Soc Nephrol 17: 2228- 2235, 2006.
20. McPherson YeeM, Jabbar SF, Osunkwo I, Clement L, Lane PA, Eckman JR, Guasch A: Chronic kidney disease and albuminuria in children with sickle cell disease. Clin J Am Soc Nephrol 6: 2628-2633, 2011.
21. Gosmanova EO, Zaidi S, Wan JY, Adams-Graves PE: Prevalence and progression of chronic kidney disease in adult patients with sickle cell disease. J Investig Med 62: 804-807, 2014.
22. Tzur S, Rosset S, Skorecki K, Wasser WG: APOL1 allelic variants are associated with lower age of dialysis initiation and thereby increased dialysis vintage in African and Hispanic Americans with non-diabetic end-stage kidney disease. Nephrol Dial Transplant 27: 1498-1505, 2012.
23. Behar DM, Rosset S, Tzur S, Selig S, Yudkovsky G, Bercovici S, Kopp JB, Winkler CA, Nelson GW, Wasser WG, Skorecki K: African ancestry allelic variation at the MYH9 gene contributes to increased susceptibility to non-diabetic end-stage kidney disease in Hispanic Americans. Hum Mol Genet 19: 1816-1827, 2010.
24. Conomos MP, Laurie CA, Stilp AM, Gogarten SM, McHugh CP, Nelson SC, Sofer T, Fernández-Rhodes L, Justice AE, Graff M, Young KL, Seyerle AA, Avery CL, Taylor KD, Rotter JI, Talavera GA, Daviglus ML, Wassertheil-Smoller S, Schneiderman N, Heiss G, Kaplan RC, Franceschini N, Reiner AP, Shaffer JR, Barr RG, Kerr KF, Browning SR, Browning BL, Weir BS, Avilés-Santa ML, Papanicolaou GJ, Lumley T, Szpiro AA, North KE, Rice K, Thornton TA, Laurie CC: Genetic Diversity and Association Studies in US Hispanic/Latino Populations: Applications in the Hispanic Community Health Study/Study of Latinos. Am J Hum Genet 98: 165-184, 2016.
25. Ricardo AC, Flessner MF, Eckfeldt JH, Eggers PW, Franceschini N, Go AS, Gotman NM, Kramer HJ, Kusek JW, Loehr LR, Melamed ML, Peralta CA, Raij L, Rosas SE, Talavera GA, Lash JP: Prevalence and Correlates of CKD in Hispanics/Latinos in the United States. Clin J Am Soc Nephrol 10: 1757-1766, 2015.
26. Böger CA, Chen MH, Tin A, Olden M, Köttgen A, de Boer IH, Fuchsberger C, O'Seaghdha CM, Pattaro C, Teumer A, Liu CT, Glazer NL, Li M, O'Connell JR, Tanaka T, Peralta CA, Kutalik Z, Luan J, Zhao JH, Hwang SJ, Akylbekova E, Kramer H, van der Harst P, Smith AV, Lohman K, de Andrade M, Hayward C, Kollerits B, Tönjes A, Aspelund T, Ingelsson E, Eiriksdottir G, Launer LJ, Harris TB, Shuldiner AR, Mitchell BD, Arking DE, Franceschini N, Boerwinkle E, Egan J, Hernandez D, Reilly M, Townsend RR, Lumley T, Siscovick DS, Psaty BM, Kestenbaum B, Haritunians T, Bergmann S, Vollenweider P, Waeber G, Mooser V, Waterworth D, Johnson AD, Florez JC, Meigs JB, Lu X, Turner ST, Atkinson EJ, Leak TS, Aasarød K, Skorpen F, Syvänen AC, Illig T, Baumert J, Koenig W, Krämer BK, Devuyst O, Mychaleckyj JC, Minelli C, Bakker SJ, Kedenko L, Paulweber B, Coassin S, Endlich K, Kroemer HK, Biffar R, Stracke S, Völzke H, Stumvoll M, Mägi R, Campbell H, Vitart V, Hastie ND, Gudnason V, Kardia SL, Liu Y, Polasek O, Curhan G, Kronenberg F, Prokopenko I, Rudan I, Arnlöv J, Hallan S, Navis G, Parsa A, Ferrucci L, Coresh J, Shlipak MG, Bull SB, Paterson NJ, Wichmann HE, Wareham NJ, Loos RJ, Rotter JI, Pramstaller PP, Cupples LA, Beckmann JS, Yang Q, Heid IM, Rettig R, Dreisbach AW, Bochud M, Fox CS, Kao WH; CKDGen Consortium: CUBN is a gene locus for albuminuria. J Am Soc Nephrol 22: 555-570, 2011.
27. Bryc K, Durand EY, Macpherson JM, Reich D, Mountain JL: The genetic ancestry of African Americans, Latinos, and EuropeanAmericans across the United States. Am J Hum Genet 96: 37-53, 2015.
28. Friedman DJ, Kozlitina J, Genovese G, Jog P, Pollak MR: Populationbased risk assessment of APOL1 on renal disease. J Am Soc Nephrol 22: 2098-2105, 2011.
29. Peralta CA, Bibbins-Domingo K, Vittinghoff E, Lin F, Fornage M, Kopp JB, Winkler CA: APOL1 genotype andrace differences in incident albuminuria and renal function decline. J Am Soc Nephrol 27: 887-893, 2016.
30. Jolly SE, Burrows NR, Chen SC, Li S, Jurkovitz CT, Narva AS, Norris KC, Shlipak MG: Racial and ethnic differences in albuminuria in individuals with estimated GFR greater than 60 mL/min/1.73 m(2): Results from the Kidney Early Evaluation Program (KEEP). Am J Kidney Dis 55[Suppl 2]: S15-S22, 2010.
31. Ma J, Guan M, Bowden DW, Ng MC, Hicks PJ, Lea JP, Ma L, Gao C, Palmer ND, Freedman BI: Association analysis of the cubilin (CUBN) and megalin (LRP2) genes with ESRD in African Americans. Clin J Am Soc Nephrol 11: 1034-1043, 2016.
32. Kozyraki R, Fyfe J, Kristiansen M, Gerdes C, Jacobsen C, Cui S, Christensen EI, Aminoff M, de la Chapelle A, Krahe R, Verroust PJ, Moestrup SK: The intrinsic factor-vitamin B12 receptor, cubilin, is a high-Affinity apolipoprotein A-I receptor facilitating endocytosis of high-density lipoprotein. Nat Med 5: 656-661, 1999.
33. Sorlie PD, Avilés-Santa LM, Wassertheil-Smoller S, Kaplan RC, Daviglus ML, Giachello AL, Schneiderman N, Raij L, Talavera G, Allison M, Lavange L, Chambless LE, Heiss G: Design and implementation of the Hispanic Community Health Study/Study of Latinos. Ann Epidemiol 20: 629-641, 2010.
34. Anonymous: Hispanic Community Health Study/Study of Latinos study manuals: Study protocol, general description and study management. Available at: https://www2.cscc.unc.edu/hchs/manualsforms. Accessed.
35. Laurie CC, Doheny KF, Mirel DB, Pugh EW, Bierut LJ, Bhangale T, Boehm F, Caporaso NE, Cornelis MC, Edenberg HJ, Gabriel SB, Harris EL, Hu FB, Jacobs KB, Kraft P, Landi MT, Lumley T, Manolio TA, McHugh C, Painter I, Paschall J, Rice JP, Rice KM, Zheng X, Weir BS; GENEVA Investigators: Quality control and quality assurance in genotypic data for genome-wide association studies. Genet Epidemiol 34: 591-602, 2010.
36. Conomos MP, Miller MB, Thornton TA: Robust inference of population structure for ancestry prediction and correction of stratification in the presence of relatedness. Genet Epidemiol 39: 276-293, 2015.
37. Alexander DH, Novembre J, Lange K: Fast model-based estimation of ancestry in unrelated individuals. Genome Res 19: 1655-1664, 2009.
38. Cavalli-Sforza LL: The Human Genome Diversity Project: past, present and future. Nat Rev Genet 6: 333-340, 2005.
39. Mattix HJ, Hsu CY, Shaykevich S, Curhan G: Use of the albumin/creatinine ratio to detect microalbuminuria: implications of sex and race. J Am Soc Nephrol 13: 1034-1039, 2002.
40. Inker LA, Schmid CH, Tighiouart H, Eckfeldt JH, Feldman HI, Greene T, Kusek JW, Manzi J, Van Lente F, Zhang YL, Coresh J, Levey AS; CKDEPI Investigators: Estimating glomerular filtration rate from serum creatinine and cystatin C. N Engl J Med 367: 20-29, 2012.
41. Chen H, Wang C, Conomos MP, Stilp AM, Li Z, Sofer T, Szpiro AA, Chen W, Brehm JM, Celedón JC, Redline S, Papanicolaou GJ, Thornton TA, Laurie CC, Rice K, Lin X: Control for population structure and relatedness for binary traits in genetic association studies via logistic mixed models. Am J Hum Genet 98: 653-666, 2016.