Digenome-seq web tool for profiling CRISPR specificity

Nature Methods

Volumn 14, Issue 6, 2017, Pages 548-549

  Park, Jeongbin ^a   Childs, Liam ^a   Kim, Daesik ^b   Hwang, Gue Ho ^c   Kim, Sunghyun ^b   Kim, Sang Tae ^b   Kim, Jin Soo ^b,d   Bae, Sangsu ^c  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b Institute for Basic Science   (South Korea)

^c Hanyang University   (South Korea)

^d Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALGORITHM; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; DIGESTED GENOME SEQUENCING; DNA FLANKING REGION; DOUBLE STRANDED DNA BREAK; LETTER; PRIORITY JOURNAL; SEQUENCE ANALYSIS; WEB BROWSER; CRISPR CAS SYSTEM; GENETICS; HIGH THROUGHPUT SEQUENCING; INTERNET; PROCEDURES; SENSITIVITY AND SPECIFICITY;

CRISPR ASSOCIATED PROTEIN;

ALGORITHMS; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; CRISPR-ASSOCIATED PROTEINS; CRISPR-CAS SYSTEMS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; INTERNET; SENSITIVITY AND SPECIFICITY;

EID: 85021845292     PISSN: 15487091     EISSN: 15487105     Source Type: Journal    
DOI: 10.1038/nmeth.4262     Document Type: Letter

References (4)

1. Kim, D. et al. Digenome-seq: Genome-wide profiling of CRISPR-Cas9 off-target effects in human cells. Nat. Methods 12, 237-243, 1, 243 (2015).
2. Kim, D., Kim, S., Kim, S., Park, J., Kim, J.S. Genome-wide target specificities of CRISPR-Cas9 nucleases revealed by multiplex Digenome-seq. Genome Res. 26, 406-415 (2016).
3. Kim, D. et al. Genome-wide analysis reveals specificities of Cpf1 endonucleases in human cells. Nat. Biotechnol. 34, 863-868 (2016).
4. Aken, B.L. et al. Ensembl 2017. Nucleic Acids Res. 45 D635-D642 (2017).