-
1
-
-
84877115165
-
How to use new biology to guide therapy in multiple myeloma
-
Morgan, G.J., Kaiser, M.F., How to use new biology to guide therapy in multiple myeloma. Hematology Am Soc Hematol Educ Program 2012 (2012), 342–349.
-
(2012)
Hematology Am Soc Hematol Educ Program
, vol.2012
, pp. 342-349
-
-
Morgan, G.J.1
Kaiser, M.F.2
-
2
-
-
84994051879
-
T cells in multiple myeloma display features of exhaustion and senescence at the tumor site
-
Zelle-Rieser, C., Thangavadivel, S., Biedermann, R., et al. T cells in multiple myeloma display features of exhaustion and senescence at the tumor site. J Hematol Oncol, 9, 2016, 116.
-
(2016)
J Hematol Oncol
, vol.9
, pp. 116
-
-
Zelle-Rieser, C.1
Thangavadivel, S.2
Biedermann, R.3
-
3
-
-
0347302952
-
Cytokines in cancer pathogenesis and cancer therapy
-
Dranoff, G., Cytokines in cancer pathogenesis and cancer therapy. Nat Rev Cancer 4 (2004), 11–22.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 11-22
-
-
Dranoff, G.1
-
4
-
-
61549087798
-
Cancer prevention by vaccination against hepatitis B
-
Chang, M.-H., Cancer prevention by vaccination against hepatitis B. Recent Results Cancer Res 181 (2009), 85–94.
-
(2009)
Recent Results Cancer Res
, vol.181
, pp. 85-94
-
-
Chang, M.-H.1
-
5
-
-
70350772293
-
Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia
-
Kenter, G.G., Welters, M.J.P., Valentijn, A.R.P.M., et al. Vaccination against HPV-16 oncoproteins for vulvar intraepithelial neoplasia. N Engl J Med 361 (2009), 1838–1847.
-
(2009)
N Engl J Med
, vol.361
, pp. 1838-1847
-
-
Kenter, G.G.1
Welters, M.J.P.2
Valentijn, A.R.P.M.3
-
6
-
-
84865552100
-
Immuno-oncology: understanding the function and dysfunction of the immune system in cancer
-
Finn, O.J., Immuno-oncology: understanding the function and dysfunction of the immune system in cancer. Ann Oncol 23:suppl 8 (2012), viii6–viii9.
-
(2012)
Ann Oncol
, vol.23
, pp. viii6-viii9
-
-
Finn, O.J.1
-
7
-
-
79953151458
-
Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion
-
Schreiber, R.D., Old, L.J., Smyth, M.J., Cancer immunoediting: integrating immunity's roles in cancer suppression and promotion. Science 331 (2011), 1565–1570.
-
(2011)
Science
, vol.331
, pp. 1565-1570
-
-
Schreiber, R.D.1
Old, L.J.2
Smyth, M.J.3
-
8
-
-
33645286546
-
Regulatory T cells, tumour immunity and immunotherapy
-
Zou, W., Regulatory T cells, tumour immunity and immunotherapy. Nat Rev Immunol 6 (2006), 295–307.
-
(2006)
Nat Rev Immunol
, vol.6
, pp. 295-307
-
-
Zou, W.1
-
9
-
-
43749102276
-
Immune surveillance: a balance between protumor and antitumor immunity
-
Ostrand-Rosenberg, S., Immune surveillance: a balance between protumor and antitumor immunity. Curr Opin Genet Dev 18 (2008), 11–18.
-
(2008)
Curr Opin Genet Dev
, vol.18
, pp. 11-18
-
-
Ostrand-Rosenberg, S.1
-
10
-
-
77951258833
-
Features of responding T cells in cancer and chronic infection
-
Kim, P.S., Ahmed, R., Features of responding T cells in cancer and chronic infection. Curr Opin Immunol 22 (2010), 223–230.
-
(2010)
Curr Opin Immunol
, vol.22
, pp. 223-230
-
-
Kim, P.S.1
Ahmed, R.2
-
11
-
-
84903555075
-
Immunological dysregulation in multiple myeloma microenvironment
-
Romano, A., Conticello, C., Cavalli, M., et al. Immunological dysregulation in multiple myeloma microenvironment. Biomed Res Int, 2014, 2014, 198539.
-
(2014)
Biomed Res Int
, vol.2014
, pp. 198539
-
-
Romano, A.1
Conticello, C.2
Cavalli, M.3
-
12
-
-
0035883073
-
Cross-presentation of tumor antigens by bone marrow-derived antigen-presenting cells is the dominant mechanism in the induction of T-cell tolerance during B-cell lymphoma progression
-
Sotomayor, E.M., Borrello, I., Rattis, F.M., et al. Cross-presentation of tumor antigens by bone marrow-derived antigen-presenting cells is the dominant mechanism in the induction of T-cell tolerance during B-cell lymphoma progression. Blood 98 (2001), 1070–1077.
-
(2001)
Blood
, vol.98
, pp. 1070-1077
-
-
Sotomayor, E.M.1
Borrello, I.2
Rattis, F.M.3
-
13
-
-
0035892109
-
Dendritic cells from patients with myeloma are numerically normal but functionally defective as they fail to up-regulate CD80 (B7-1) expression after huCD40LT stimulation because of inhibition by transforming growth factor-beta1 and interleukin-10
-
Brown, R.D., Pope, B., Murray, A., et al. Dendritic cells from patients with myeloma are numerically normal but functionally defective as they fail to up-regulate CD80 (B7-1) expression after huCD40LT stimulation because of inhibition by transforming growth factor-beta1 and interleukin-10. Blood 98 (2001), 2992–2998.
-
(2001)
Blood
, vol.98
, pp. 2992-2998
-
-
Brown, R.D.1
Pope, B.2
Murray, A.3
-
14
-
-
33645098467
-
Impaired functionality and phenotypic profile of dendritic cells from patients with multiple myeloma
-
Brimnes, M.K., Svane, I.M., Johnsen, H.E., Impaired functionality and phenotypic profile of dendritic cells from patients with multiple myeloma. Clin Exp Immunol 144 (2006), 76–84.
-
(2006)
Clin Exp Immunol
, vol.144
, pp. 76-84
-
-
Brimnes, M.K.1
Svane, I.M.2
Johnsen, H.E.3
-
15
-
-
77954721060
-
Regulatory T cells in tumor immunity
-
Nishikawa, H., Sakaguchi, S., Regulatory T cells in tumor immunity. Int J Cancer 127 (2010), 759–767.
-
(2010)
Int J Cancer
, vol.127
, pp. 759-767
-
-
Nishikawa, H.1
Sakaguchi, S.2
-
16
-
-
4143130091
-
Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses
-
Rodriguez, P.C., Quiceno, D.G., Zabaleta, J., et al. Arginase I production in the tumor microenvironment by mature myeloid cells inhibits T-cell receptor expression and antigen-specific T-cell responses. Cancer Res 64 (2004), 5839–5849.
-
(2004)
Cancer Res
, vol.64
, pp. 5839-5849
-
-
Rodriguez, P.C.1
Quiceno, D.G.2
Zabaleta, J.3
-
17
-
-
84884164729
-
CS1, a SLAM family receptor involved in immune regulation, is a therapeutic target in multiple myeloma
-
Veillette, A., Guo, H., CS1, a SLAM family receptor involved in immune regulation, is a therapeutic target in multiple myeloma. Crit Rev Oncol Hematol 88 (2013), 168–177.
-
(2013)
Crit Rev Oncol Hematol
, vol.88
, pp. 168-177
-
-
Veillette, A.1
Guo, H.2
-
18
-
-
60749124123
-
Influence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell function
-
Cruz-Munoz, M.-E., Dong, Z., Shi, X., Zhang, S., Veillette, A., Influence of CRACC, a SLAM family receptor coupled to the adaptor EAT-2, on natural killer cell function. Nat Immunol 10 (2009), 297–305.
-
(2009)
Nat Immunol
, vol.10
, pp. 297-305
-
-
Cruz-Munoz, M.-E.1
Dong, Z.2
Shi, X.3
Zhang, S.4
Veillette, A.5
-
19
-
-
84933569079
-
Elotuzumab therapy for relapsed or refractory multiple myeloma
-
Lonial, S., Dimopoulos, M., Palumbo, A., et al. Elotuzumab therapy for relapsed or refractory multiple myeloma. N Engl J Med 373 (2015), 621–631.
-
(2015)
N Engl J Med
, vol.373
, pp. 621-631
-
-
Lonial, S.1
Dimopoulos, M.2
Palumbo, A.3
-
20
-
-
84974633304
-
Randomized phase 2 study: elotuzumab plus bortezomib/dexamethasone vs bortezomib/dexamethasone for relapsed/refractory multiple myeloma
-
Jakubowiak, A., Offidani, M., Pégourie, B., et al. Randomized phase 2 study: elotuzumab plus bortezomib/dexamethasone vs bortezomib/dexamethasone for relapsed/refractory multiple myeloma. Blood 127 (2016), 2833–2840.
-
(2016)
Blood
, vol.127
, pp. 2833-2840
-
-
Jakubowiak, A.1
Offidani, M.2
Pégourie, B.3
-
21
-
-
1642348370
-
Flow cytometric immunophenotypic analysis of 306 cases of multiple myeloma
-
Lin, P., Owens, R., Tricot, G., Wilson, C.S., Flow cytometric immunophenotypic analysis of 306 cases of multiple myeloma. Am J Clin Pathol 121 (2004), 482–488.
-
(2004)
Am J Clin Pathol
, vol.121
, pp. 482-488
-
-
Lin, P.1
Owens, R.2
Tricot, G.3
Wilson, C.S.4
-
22
-
-
1842611807
-
Flow cytometric detection of aneuploid CD38(++) plasmacells and CD19(+) B-lymphocytes in bone marrow, peripheral blood and PBSC harvest in multiple myeloma patients
-
Santonocito, A.M., Consoli, U., Bagnato, S., et al. Flow cytometric detection of aneuploid CD38(++) plasmacells and CD19(+) B-lymphocytes in bone marrow, peripheral blood and PBSC harvest in multiple myeloma patients. Leuk Res 28 (2004), 469–477.
-
(2004)
Leuk Res
, vol.28
, pp. 469-477
-
-
Santonocito, A.M.1
Consoli, U.2
Bagnato, S.3
-
23
-
-
79251570884
-
Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors
-
de Weers, M., Tai, Y.-T., van der Veer, M.S., et al. Daratumumab, a novel therapeutic human CD38 monoclonal antibody, induces killing of multiple myeloma and other hematological tumors. J Immunol 186 (2011), 1840–1848.
-
(2011)
J Immunol
, vol.186
, pp. 1840-1848
-
-
de Weers, M.1
Tai, Y.-T.2
van der Veer, M.S.3
-
24
-
-
84924546237
-
Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma
-
Overdijk, M.B., Verploegen, S., Bögels, M., et al. Antibody-mediated phagocytosis contributes to the anti-tumor activity of the therapeutic antibody daratumumab in lymphoma and multiple myeloma. MAbs 7 (2015), 311–321.
-
(2015)
MAbs
, vol.7
, pp. 311-321
-
-
Overdijk, M.B.1
Verploegen, S.2
Bögels, M.3
-
25
-
-
84994625957
-
Immunomodulatory effects and adaptive immune response to daratumumab in multiple myeloma
-
(abstract 3037)
-
Krejcik, J., Casneuf, T., Nijhof, I., et al. Immunomodulatory effects and adaptive immune response to daratumumab in multiple myeloma. Blood, 126, 2015 (abstract 3037).
-
(2015)
Blood
, vol.126
-
-
Krejcik, J.1
Casneuf, T.2
Nijhof, I.3
-
26
-
-
84942436321
-
Targeting CD38 with daratumumab monotherapy in multiple myeloma
-
Lokhorst, H.M., Plesner, T., Laubach, J.P., et al. Targeting CD38 with daratumumab monotherapy in multiple myeloma. N Engl J Med 373 (2015), 1207–1219.
-
(2015)
N Engl J Med
, vol.373
, pp. 1207-1219
-
-
Lokhorst, H.M.1
Plesner, T.2
Laubach, J.P.3
-
27
-
-
84946713813
-
Phase II study of daratumumab (DARA) monotherapy in patients with ≥ 3 lines of prior therapy or double refractory multiple myeloma (MM): 54767414MMY2002 (Sirius)
-
2015 ASCO Annual Meeting | Abstracts | Meeting Library (abstract LBA8512)
-
Lonial, S., Weiss, B.M., Usmani, S.Z., et al. Phase II study of daratumumab (DARA) monotherapy in patients with ≥ 3 lines of prior therapy or double refractory multiple myeloma (MM): 54767414MMY2002 (Sirius). 2015 ASCO Annual Meeting | Abstracts | Meeting Library ASCO, 2015 (abstract LBA8512).
-
(2015)
ASCO
-
-
Lonial, S.1
Weiss, B.M.2
Usmani, S.Z.3
-
28
-
-
84984680198
-
Daratumumab, bortezomib, and dexamethasone for multiple myeloma
-
Palumbo, A., Chanan-Khan, A., Weisel, K., et al. Daratumumab, bortezomib, and dexamethasone for multiple myeloma. N Engl J Med 375 (2016), 754–766.
-
(2016)
N Engl J Med
, vol.375
, pp. 754-766
-
-
Palumbo, A.1
Chanan-Khan, A.2
Weisel, K.3
-
29
-
-
84990046018
-
Daratumumab, lenalidomide, and dexamethasone for multiple myeloma
-
Dimopoulos, M.A., Oriol, A., Nahi, H., et al. Daratumumab, lenalidomide, and dexamethasone for multiple myeloma. N Engl J Med 375 (2016), 1319–1331.
-
(2016)
N Engl J Med
, vol.375
, pp. 1319-1331
-
-
Dimopoulos, M.A.1
Oriol, A.2
Nahi, H.3
-
30
-
-
78049386125
-
Immunomodulatory effects of lenalidomide and pomalidomide on interaction of tumor and bone marrow accessory cells in multiple myeloma
-
Görgün, G., Calabrese, E., Soydan, E., et al. Immunomodulatory effects of lenalidomide and pomalidomide on interaction of tumor and bone marrow accessory cells in multiple myeloma. Blood 116 (2010), 3227–3237.
-
(2010)
Blood
, vol.116
, pp. 3227-3237
-
-
Görgün, G.1
Calabrese, E.2
Soydan, E.3
-
31
-
-
10744231369
-
Immunomodulatory drug costimulates T cells via the B7-CD28 pathway
-
LeBlanc, R., Hideshima, T., Catley, L.P., et al. Immunomodulatory drug costimulates T cells via the B7-CD28 pathway. Blood 103 (2004), 1787–1790.
-
(2004)
Blood
, vol.103
, pp. 1787-1790
-
-
LeBlanc, R.1
Hideshima, T.2
Catley, L.P.3
-
32
-
-
79960494739
-
Lenalidomide enhances antigen-specific activity and decreases CD45RA expression of T cells from patients with multiple myeloma
-
Neuber, B., Herth, I., Tolliver, C., et al. Lenalidomide enhances antigen-specific activity and decreases CD45RA expression of T cells from patients with multiple myeloma. J Immunol 187 (2011), 1047–1056.
-
(2011)
J Immunol
, vol.187
, pp. 1047-1056
-
-
Neuber, B.1
Herth, I.2
Tolliver, C.3
-
33
-
-
85028290944
-
Marrow infiltrating lymphocytes and vaccines in myeloma
-
(abstract SCI-35)
-
Borrello, I., Marrow infiltrating lymphocytes and vaccines in myeloma. Blood, 128, 2016 (abstract SCI-35).
-
(2016)
Blood
, vol.128
-
-
Borrello, I.1
-
34
-
-
84858766182
-
The blockade of immune checkpoints in cancer immunotherapy
-
Pardoll, D.M., The blockade of immune checkpoints in cancer immunotherapy. Nat Rev Cancer 12 (2012), 252–264.
-
(2012)
Nat Rev Cancer
, vol.12
, pp. 252-264
-
-
Pardoll, D.M.1
-
35
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan, D., Weinberg, R.A., Hallmarks of cancer: the next generation. Cell 144 (2011), 646–674.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
36
-
-
61849165013
-
CTLA4 blockade with ipilimumab to treat relapse of malignancy after allogeneic hematopoietic cell transplantation
-
Bashey, A., Medina, B., Corringham, S., et al. CTLA4 blockade with ipilimumab to treat relapse of malignancy after allogeneic hematopoietic cell transplantation. Blood 113 (2009), 1581–1588.
-
(2009)
Blood
, vol.113
, pp. 1581-1588
-
-
Bashey, A.1
Medina, B.2
Corringham, S.3
-
37
-
-
84979240618
-
Nivolumab in patients with relapsed or refractory hematologic malignancy: preliminary results of a phase Ib study
-
Lesokhin, A.M., Ansell, S.M., Armand, P., et al. Nivolumab in patients with relapsed or refractory hematologic malignancy: preliminary results of a phase Ib study. J Clin Oncol 34 (2016), 2698–2704.
-
(2016)
J Clin Oncol
, vol.34
, pp. 2698-2704
-
-
Lesokhin, A.M.1
Ansell, S.M.2
Armand, P.3
-
38
-
-
85007202056
-
Pembrolizumab in combination with lenalidomide and low-dose dexamethasone for relapsed/refractory multiple myeloma (RRMM): Final efficacy and safety analysis
-
2016 ASCO Annual Meeting | Abstracts | Meeting Library (abstract 8010)
-
Mateos, M.-V., Orlowski, R.Z., Siegel, D.S.D., et al. Pembrolizumab in combination with lenalidomide and low-dose dexamethasone for relapsed/refractory multiple myeloma (RRMM): Final efficacy and safety analysis. 2016 ASCO Annual Meeting | Abstracts | Meeting Library ASCO, 34, 2016 (abstract 8010).
-
(2016)
ASCO
, vol.34
-
-
Mateos, M.-V.1
Orlowski, R.Z.2
Siegel, D.S.D.3
-
39
-
-
85018385808
-
Pembrolizumab in combination with pomalidomide and dexamethasone for relapsed/refractory multiple myeloma (RRMM)
-
(abstract 490)
-
Badros, A.Z., Hyjek, E., Ma, N., et al. Pembrolizumab in combination with pomalidomide and dexamethasone for relapsed/refractory multiple myeloma (RRMM). Blood, 128, 2016 (abstract 490).
-
(2016)
Blood
, vol.128
-
-
Badros, A.Z.1
Hyjek, E.2
Ma, N.3
-
40
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi, F.S., O'Day, S.J., McDermott, D.F., et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 363 (2010), 711–723.
-
(2010)
N Engl J Med
, vol.363
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
41
-
-
0028867420
-
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
-
Tivol, E.A., Borriello, F., Schweitzer, A.N., et al. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 3 (1995), 541–547.
-
(1995)
Immunity
, vol.3
, pp. 541-547
-
-
Tivol, E.A.1
Borriello, F.2
Schweitzer, A.N.3
-
42
-
-
82255192901
-
The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses
-
Walker, L.S.K., Sansom, D.M., The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses. Nat Rev Immunol 11 (2011), 852–863.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 852-863
-
-
Walker, L.S.K.1
Sansom, D.M.2
-
43
-
-
0028237348
-
CD28-B7 interactions in T-cell activation
-
Allison, J.P., CD28-B7 interactions in T-cell activation. Curr Opin Immunol 6 (1994), 414–419.
-
(1994)
Curr Opin Immunol
, vol.6
, pp. 414-419
-
-
Allison, J.P.1
-
44
-
-
84961528534
-
Immunomodulatory molecule PD-L1 is expressed on malignant plasma cells and myeloma-propagating pre-plasma cells in the bone marrow of multiple myeloma patients
-
Yousef, S., Marvin, J., Steinbach, M., et al. Immunomodulatory molecule PD-L1 is expressed on malignant plasma cells and myeloma-propagating pre-plasma cells in the bone marrow of multiple myeloma patients. Blood Cancer J, 5, 2015, e285.
-
(2015)
Blood Cancer J
, vol.5
, pp. e285
-
-
Yousef, S.1
Marvin, J.2
Steinbach, M.3
-
45
-
-
42649125225
-
PD-1 and its ligands in tolerance and immunity
-
Keir, M.E., Butte, M.J., Freeman, G.J., Sharpe, A.H., PD-1 and its ligands in tolerance and immunity. Annu Rev Immunol 26 (2008), 677–704.
-
(2008)
Annu Rev Immunol
, vol.26
, pp. 677-704
-
-
Keir, M.E.1
Butte, M.J.2
Freeman, G.J.3
Sharpe, A.H.4
-
46
-
-
0033180181
-
Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor
-
Nishimura, H., Nose, M., Hiai, H., Minato, N., Honjo, T., Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor. Immunity 11 (1999), 141–151.
-
(1999)
Immunity
, vol.11
, pp. 141-151
-
-
Nishimura, H.1
Nose, M.2
Hiai, H.3
Minato, N.4
Honjo, T.5
-
47
-
-
49249089425
-
Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways
-
Fife, B.T., Bluestone, J.A., Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways. Immunol Rev 224 (2008), 166–182.
-
(2008)
Immunol Rev
, vol.224
, pp. 166-182
-
-
Fife, B.T.1
Bluestone, J.A.2
-
48
-
-
84957839638
-
CTLA-4 and PD-1 pathways: similarities, differences, and implications of their inhibition
-
Buchbinder, E.I., Desai, A., CTLA-4 and PD-1 pathways: similarities, differences, and implications of their inhibition. Am J Clin Oncol 39 (2016), 98–106.
-
(2016)
Am J Clin Oncol
, vol.39
, pp. 98-106
-
-
Buchbinder, E.I.1
Desai, A.2
-
49
-
-
84925545111
-
Clinical blockade of PD1 and LAG3—potential mechanisms of action
-
Nguyen, L.T., Ohashi, P.S., Clinical blockade of PD1 and LAG3—potential mechanisms of action. Nat Rev Immunol 15 (2015), 45–56.
-
(2015)
Nat Rev Immunol
, vol.15
, pp. 45-56
-
-
Nguyen, L.T.1
Ohashi, P.S.2
-
50
-
-
34347400169
-
Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-{gamma} and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway
-
Liu, J., Hamrouni, A., Wolowiec, D., et al. Plasma cells from multiple myeloma patients express B7-H1 (PD-L1) and increase expression after stimulation with IFN-{gamma} and TLR ligands via a MyD88-, TRAF6-, and MEK-dependent pathway. Blood 110 (2007), 296–304.
-
(2007)
Blood
, vol.110
, pp. 296-304
-
-
Liu, J.1
Hamrouni, A.2
Wolowiec, D.3
-
51
-
-
79960218752
-
Immunosuppressive effects of multiple myeloma are overcome by PD-L1 blockade
-
Hallett, W.H.D., Jing, W., Drobyski, W.R., Johnson, B.D., Immunosuppressive effects of multiple myeloma are overcome by PD-L1 blockade. Biol Blood Marrow Transplant 17 (2011), 1133–1145.
-
(2011)
Biol Blood Marrow Transplant
, vol.17
, pp. 1133-1145
-
-
Hallett, W.H.D.1
Jing, W.2
Drobyski, W.R.3
Johnson, B.D.4
-
52
-
-
84861064002
-
Programmed death ligand 2 in cancer-induced immune suppression
-
Rozali, E.N., Hato, S.V., Robinson, B.W., Lake, R.A., Lesterhuis, W.J., Programmed death ligand 2 in cancer-induced immune suppression. Clin Dev Immunol, 2012, 2012, 656340.
-
(2012)
Clin Dev Immunol
, vol.2012
, pp. 656340
-
-
Rozali, E.N.1
Hato, S.V.2
Robinson, B.W.3
Lake, R.A.4
Lesterhuis, W.J.5
-
53
-
-
84945586394
-
Lenalidomide enhances immune checkpoint blockade-induced immune response in multiple myeloma
-
Görgün, G., Samur, M.K., Cowens, K.B., et al. Lenalidomide enhances immune checkpoint blockade-induced immune response in multiple myeloma. Clin Cancer Res 21 (2015), 4607–4618.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 4607-4618
-
-
Görgün, G.1
Samur, M.K.2
Cowens, K.B.3
-
54
-
-
84936147067
-
Combined nivolumab and ipilimumab or monotherapy in untreated melanoma
-
Larkin, J., Chiarion-Sileni, V., Gonzalez, R., et al. Combined nivolumab and ipilimumab or monotherapy in untreated melanoma. N Engl J Med 373 (2015), 23–34.
-
(2015)
N Engl J Med
, vol.373
, pp. 23-34
-
-
Larkin, J.1
Chiarion-Sileni, V.2
Gonzalez, R.3
-
55
-
-
84925221855
-
PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma
-
Ansell, S.M., Lesokhin, A.M., Borrello, I., et al. PD-1 blockade with nivolumab in relapsed or refractory Hodgkin's lymphoma. N Engl J Med 372 (2015), 311–319.
-
(2015)
N Engl J Med
, vol.372
, pp. 311-319
-
-
Ansell, S.M.1
Lesokhin, A.M.2
Borrello, I.3
-
56
-
-
85020307528
-
The long PD-1 receptor binding kinetics of nivolumab may increase efficacy of subsequent therapy in relapsed and refractory multiple myeloma patients
-
(abstract 3057)
-
Funt, S.A., Page, D.B., Cattry, D., et al. The long PD-1 receptor binding kinetics of nivolumab may increase efficacy of subsequent therapy in relapsed and refractory multiple myeloma patients. Blood, 126, 2015 (abstract 3057).
-
(2015)
Blood
, vol.126
-
-
Funt, S.A.1
Page, D.B.2
Cattry, D.3
-
58
-
-
84991543926
-
Killer immunoglobulin-like receptors and tumor immunity
-
Benson, D.M., Caligiuri, M.A., Killer immunoglobulin-like receptors and tumor immunity. Cancer Immunol Res 2 (2014), 99–104.
-
(2014)
Cancer Immunol Res
, vol.2
, pp. 99-104
-
-
Benson, D.M.1
Caligiuri, M.A.2
-
59
-
-
84869819029
-
A phase 1 trial of the anti-KIR antibody IPH2101 in patients with relapsed/refractory multiple myeloma
-
Benson, D.M., Hofmeister, C.C., Padmanabhan, S., et al. A phase 1 trial of the anti-KIR antibody IPH2101 in patients with relapsed/refractory multiple myeloma. Blood 120 (2012), 4324–4333.
-
(2012)
Blood
, vol.120
, pp. 4324-4333
-
-
Benson, D.M.1
Hofmeister, C.C.2
Padmanabhan, S.3
-
60
-
-
19944428928
-
HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells
-
Carbone, E., Neri, P., Mesuraca, M., et al. HLA class I, NKG2D, and natural cytotoxicity receptors regulate multiple myeloma cell recognition by natural killer cells. Blood 105 (2005), 251–258.
-
(2005)
Blood
, vol.105
, pp. 251-258
-
-
Carbone, E.1
Neri, P.2
Mesuraca, M.3
-
61
-
-
84964255580
-
Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide
-
Nijhof, I.S., Lammerts van Bueren, J.J., van Kessel, B., et al. Daratumumab-mediated lysis of primary multiple myeloma cells is enhanced in combination with the human anti-KIR antibody IPH2102 and lenalidomide. Haematologica 100 (2015), 263–268.
-
(2015)
Haematologica
, vol.100
, pp. 263-268
-
-
Nijhof, I.S.1
Lammerts van Bueren, J.J.2
van Kessel, B.3
-
62
-
-
84901712243
-
A phase II trial of pan-KIR2D blockade with IPH2101 in smoldering multiple myeloma
-
Korde, N., Carlsten, M., Lee, M.-J., et al. A phase II trial of pan-KIR2D blockade with IPH2101 in smoldering multiple myeloma. Haematologica 99 (2014), e81–e83.
-
(2014)
Haematologica
, vol.99
, pp. e81-e83
-
-
Korde, N.1
Carlsten, M.2
Lee, M.-J.3
-
63
-
-
84942933304
-
A phase I trial of the anti-KIR antibody IPH2101 and lenalidomide in patients with relapsed/refractory multiple myeloma
-
Benson, D.M., Cohen, A.D., Jagannath, S., et al. A phase I trial of the anti-KIR antibody IPH2101 and lenalidomide in patients with relapsed/refractory multiple myeloma. Clin Cancer Res 21 (2015), 4055–4061.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 4055-4061
-
-
Benson, D.M.1
Cohen, A.D.2
Jagannath, S.3
-
64
-
-
80052139996
-
Redirecting T cells
-
Urba, W.J., Longo, D.L., Redirecting T cells. N Engl J Med 365 (2011), 754–757.
-
(2011)
N Engl J Med
, vol.365
, pp. 754-757
-
-
Urba, W.J.1
Longo, D.L.2
-
65
-
-
84890192292
-
Hematopoietic stem cells for cancer immunotherapy
-
Gschweng, E., De Oliveira, S., Kohn, D.B., Hematopoietic stem cells for cancer immunotherapy. Immunol Rev 257 (2014), 237–249.
-
(2014)
Immunol Rev
, vol.257
, pp. 237-249
-
-
Gschweng, E.1
De Oliveira, S.2
Kohn, D.B.3
-
66
-
-
84876325876
-
Chimeric antigen receptor-modified T cells for acute lymphoid leukemia
-
Grupp, S.A., Kalos, M., Barrett, D., et al. Chimeric antigen receptor-modified T cells for acute lymphoid leukemia. N Engl J Med 368 (2013), 1509–1518.
-
(2013)
N Engl J Med
, vol.368
, pp. 1509-1518
-
-
Grupp, S.A.1
Kalos, M.2
Barrett, D.3
-
67
-
-
84876005284
-
CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia
-
Brentjens, R.J., Davila, M.L., Riviere, I., et al. CD19-targeted T cells rapidly induce molecular remissions in adults with chemotherapy-refractory acute lymphoblastic leukemia. Sci Transl Med, 5, 2013, 177ra38.
-
(2013)
Sci Transl Med
, vol.5
, pp. 177ra38
-
-
Brentjens, R.J.1
Davila, M.L.2
Riviere, I.3
-
68
-
-
84940881287
-
Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia
-
Porter, D.L., Hwang, W.-T., Frey, N.V., et al. Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia. Sci Transl Med, 7, 2015, 303ra139.
-
(2015)
Sci Transl Med
, vol.7
, pp. 303ra139
-
-
Porter, D.L.1
Hwang, W.-T.2
Frey, N.V.3
-
69
-
-
84894273737
-
Flow cytometric differentiation of abnormal and normal plasma cells in the bone marrow in patients with multiple myeloma and its precursor diseases
-
Tembhare, P.R., Yuan, C.M., Venzon, D., et al. Flow cytometric differentiation of abnormal and normal plasma cells in the bone marrow in patients with multiple myeloma and its precursor diseases. Leuk Res 38 (2014), 371–376.
-
(2014)
Leuk Res
, vol.38
, pp. 371-376
-
-
Tembhare, P.R.1
Yuan, C.M.2
Venzon, D.3
-
70
-
-
84887611170
-
Myeloma stem cell concepts, heterogeneity and plasticity of multiple myeloma
-
Hajek, R., Okubote, S.A., Svachova, H., Myeloma stem cell concepts, heterogeneity and plasticity of multiple myeloma. Br J Haematol 163 (2013), 551–564.
-
(2013)
Br J Haematol
, vol.163
, pp. 551-564
-
-
Hajek, R.1
Okubote, S.A.2
Svachova, H.3
-
71
-
-
84941312389
-
Chimeric antigen receptor T cells against CD19 for multiple myeloma
-
Garfall, A.L., Maus, M.V., Hwang, W.-T., et al. Chimeric antigen receptor T cells against CD19 for multiple myeloma. N Engl J Med 373 (2015), 1040–1047.
-
(2015)
N Engl J Med
, vol.373
, pp. 1040-1047
-
-
Garfall, A.L.1
Maus, M.V.2
Hwang, W.-T.3
-
72
-
-
85023614898
-
Pilot study of anti-CD19 chimeric antigen receptor T cells (CTL019) in conjunction with salvage autologous stem cell transplantation for advanced multiple myeloma
-
(abstract 974)
-
Garfall, A.L., Stadtmauer, E.A., Maus, M.V., et al. Pilot study of anti-CD19 chimeric antigen receptor T cells (CTL019) in conjunction with salvage autologous stem cell transplantation for advanced multiple myeloma. Blood, 128, 2016 (abstract 974).
-
(2016)
Blood
, vol.128
-
-
Garfall, A.L.1
Stadtmauer, E.A.2
Maus, M.V.3
-
73
-
-
84983221034
-
T cells expressing an anti-B-cell-maturation-antigen chimeric antigen receptor cause remissions of multiple myeloma
-
Ali, S.A., Shi, V., Maric, I., et al. T cells expressing an anti-B-cell-maturation-antigen chimeric antigen receptor cause remissions of multiple myeloma. Blood 128 (2016), 1688–1700.
-
(2016)
Blood
, vol.128
, pp. 1688-1700
-
-
Ali, S.A.1
Shi, V.2
Maric, I.3
-
74
-
-
85020572876
-
B-cell maturation antigen (BCMA)-specific chimeric antigen receptor T cells (CART-BCMA) for multiple myeloma (MM): initial safety and efficacy from a phase I study
-
(abstract 1147)
-
Cohen, A.D., Garfall, A.L., Stadtmauer, E.A., et al. B-cell maturation antigen (BCMA)-specific chimeric antigen receptor T cells (CART-BCMA) for multiple myeloma (MM): initial safety and efficacy from a phase I study. Blood, 128, 2016 (abstract 1147).
-
(2016)
Blood
, vol.128
-
-
Cohen, A.D.1
Garfall, A.L.2
Stadtmauer, E.A.3
-
75
-
-
85028284553
-
Clinical remissions and limited toxicity in a first-in-human multicenter study of bb2121, a novel anti-BCMA CAR T cell therapy for relapsed/refractory multiple myeloma
-
Berdeja, J.G., Lin, Y., Raje, N., et al. Clinical remissions and limited toxicity in a first-in-human multicenter study of bb2121, a novel anti-BCMA CAR T cell therapy for relapsed/refractory multiple myeloma. Eur J Cancer, 69, 2016, S5.
-
(2016)
Eur J Cancer
, vol.69
, pp. S5
-
-
Berdeja, J.G.1
Lin, Y.2
Raje, N.3
-
76
-
-
8944235348
-
A plasmocyte selective monoclonal antibody (B-B4) recognizes syndecan-1
-
Wijdenes, J., Vooijs, W.C., Clément, C., et al. A plasmocyte selective monoclonal antibody (B-B4) recognizes syndecan-1. Br J Haematol 94 (1996), 318–323.
-
(1996)
Br J Haematol
, vol.94
, pp. 318-323
-
-
Wijdenes, J.1
Vooijs, W.C.2
Clément, C.3
-
77
-
-
84879588054
-
BT062, an antibody-drug conjugate directed against CD138, given weekly for 3 weeks in each 4 week cycle: safety and further evidence of clinical activity
-
(abstract 4042)
-
Heffner, L.T., Jagannath, S., Zimmerman, T.M., et al. BT062, an antibody-drug conjugate directed against CD138, given weekly for 3 weeks in each 4 week cycle: safety and further evidence of clinical activity. Blood, 120, 2015 (abstract 4042).
-
(2015)
Blood
, vol.120
-
-
Heffner, L.T.1
Jagannath, S.2
Zimmerman, T.M.3
-
78
-
-
33845256434
-
T lymphocytes redirected against the kappa light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells
-
Vera, J., Savoldo, B., Vigouroux, S., et al. T lymphocytes redirected against the kappa light chain of human immunoglobulin efficiently kill mature B lymphocyte-derived malignant cells. Blood 108 (2006), 3890–3897.
-
(2006)
Blood
, vol.108
, pp. 3890-3897
-
-
Vera, J.1
Savoldo, B.2
Vigouroux, S.3
-
80
-
-
84977477922
-
Toxicities of chimeric antigen receptor T cells: recognition and management
-
Brudno, J.N., Kochenderfer, J.N., Toxicities of chimeric antigen receptor T cells: recognition and management. Blood 127 (2016), 3321–3330.
-
(2016)
Blood
, vol.127
, pp. 3321-3330
-
-
Brudno, J.N.1
Kochenderfer, J.N.2
-
81
-
-
85028243901
-
Posterior reversible encephalopathy syndrome (PRES) after infusion of anti-Bcma CAR T cells (CART-BCMA) for multiple myeloma: successful treatment with cyclophosphamide
-
(abstract 5702)
-
Garfall, A.L., Lancaster, E., Stadtmauer, E.A., et al. Posterior reversible encephalopathy syndrome (PRES) after infusion of anti-Bcma CAR T cells (CART-BCMA) for multiple myeloma: successful treatment with cyclophosphamide. Blood, 128, 2016 (abstract 5702).
-
(2016)
Blood
, vol.128
-
-
Garfall, A.L.1
Lancaster, E.2
Stadtmauer, E.A.3
|