Polygenic burdens on cell-specific pathways underlie the risk of rheumatoid arthritis

Nature Genetics

Volumn 49, Issue 7, 2017, Pages 1120-1125

  Ishigaki, Kazuyoshi ^a,b   Kochi, Yuta ^a,c   Suzuki, Akari ^a   Tsuchida, Yumi ^b   Tsuchiya, Haruka ^b   Sumitomo, Shuji ^b   Yamaguchi, Kensuke ^a,b   Nagafuchi, Yasuo ^b   Nakachi, Shinichiro ^b   Kato, Rika ^b   Sakurai, Keiichi ^b   Shoda, Hirofumi ^b   Ikari, Katsunori ^c,d   Taniguchi, Atsuo ^d   Yamanaka, Hisashi ^d   Miya, Fuyuki ^a,c,e   Tsunoda, Tatsuhiko ^a,c,e   Okada, Yukinori ^a,f,g   Momozawa, Yukihide ^a   Kamatani, Yoichiro ^a   Yamada, Ryo ^a,h   Kubo, Michiaki ^a   Fujio, Keishi ^b   Yamamoto, Kazuhiko ^a,b   more..

^a Institute of Physical and Chemical Research   (Japan)

^b UNIVERSITY OF TOKYO   (Japan)

^c JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^d TOKYO WOMEN'S MEDICAL UNIVERSITY   (Japan)

^e TOKYO MEDICAL AND DENTAL UNIVERSITY   (Japan)

^f OSAKA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^g OSAKA UNIVERSITY   (Japan)

^h KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; CD8 ANTIGEN; TUMOR NECROSIS FACTOR; CYTOKINE;

ADULT; ARTICLE; B LYMPHOCYTE; BLOOD; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; FEMALE; GENE EXPRESSION; GENETIC ANALYSIS; GENETIC ASSOCIATION; HUMAN; IMMUNOCOMPETENT CELL; JAPANESE (PEOPLE); MALE; MONOCYTE; NATURAL KILLER CELL; NORMAL HUMAN; PREDICTION; PRIORITY JOURNAL; QUANTITATIVE TRAIT LOCUS; RHEUMATOID ARTHRITIS; UPREGULATION; ALLELE; ASIAN CONTINENTAL ANCESTRY GROUP; AUTOIMMUNE DISEASE; BIOLOGICAL MODEL; ETHNOLOGY; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; IMMUNE SYSTEM; IMMUNOLOGY; INFLAMMATION; MULTIFACTORIAL INHERITANCE; RISK; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; ALLELES; ARTHRITIS, RHEUMATOID; ASIAN CONTINENTAL ANCESTRY GROUP; AUTOIMMUNE DISEASES; CYTOKINES; FEMALE; GENE EXPRESSION PROFILING; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; IMMUNE SYSTEM; INFLAMMATION; MALE; MODELS, GENETIC; MULTIFACTORIAL INHERITANCE; POLYMORPHISM, SINGLE NUCLEOTIDE; QUANTITATIVE TRAIT LOCI; RISK;

EID: 85021722632     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3885     Document Type: Article

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