Antiproliferative and apoptotic effects of novel anti-ROR1 single-chain antibodies in hematological malignancies

SLAS Discovery

Volumn 22, Issue 4, 2017, Pages 408-417

  Aghebati Maleki, Leili ^a,b   Younesi, Vahid ^c,d   Baradaran, Behzad ^a   Abdolalizadeh, Jalal ^a   Motallebnezhad, Morteza ^a,b   Nickho, Hamid ^a,b   Shanehbandi, Dariush ^a   Majidi, Jafar ^a   Yousefi, Mehdi ^a,b  

^a TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TABRIZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c ALBORZ UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d Pishtaz Teb Medical Co   (Iran)

Author keywords

Hematological malignancies; Immunotherapy; Phage display; ROR1; scFv

Indexed keywords

BOVINE SERUM ALBUMIN; FRIZZLED PROTEIN; LIPOCORTIN 5; RECEPTOR TYROSINE KINASE LIKE ORPHAN RECEPTOR; RECEPTOR TYROSINE KINASE LIKE ORPHAN RECEPTOR 1; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; SOMATOMEDIN C RECEPTOR; UNCLASSIFIED DRUG; IMMUNOLOGICAL ANTINEOPLASTIC AGENT; PEPTIDE; ROR1 PROTEIN, HUMAN; TUMOR PROTEIN;

ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; APOPTOSIS ASSAY; ARTICLE; CANCER CELL LINE; CELL DEATH; CELL GROWTH; CHRONIC LYMPHATIC LEUKEMIA; COLONY FORMING UNIT; CONTROLLED STUDY; DNA SEQUENCE; ELECTROPHORESIS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE LIBRARY; HEMATOLOGIC MALIGNANCY; HUMAN; HUMAN CELL; LYMPHOMA; MYELOMA; POLYMERASE CHAIN REACTION; SEQUENCE ANALYSIS; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; CELL PROLIFERATION; CELL SURFACE DISPLAY; CHEMISTRY; DRUG EFFECT; ESCHERICHIA COLI; GENE EXPRESSION; GENETICS; IMMUNOLOGY; METABOLISM; PROCEDURES; TUMOR CELL LINE; VIROLOGY;

ANTINEOPLASTIC AGENTS, IMMUNOLOGICAL; APOPTOSIS; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURFACE DISPLAY TECHNIQUES; ENZYME-LINKED IMMUNOSORBENT ASSAY; ESCHERICHIA COLI; GENE EXPRESSION; HUMANS; NEOPLASM PROTEINS; PEPTIDES; RECEPTOR TYROSINE KINASE-LIKE ORPHAN RECEPTORS; SINGLE-CHAIN ANTIBODIES;

EID: 85021672475     PISSN: 24725552     EISSN: 24725560     Source Type: Journal    
DOI: 10.1177/2472555216689659     Document Type: Article

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