-
1
-
-
84997749022
-
Abstract PR14: integrative functional genomics of breast cancer
-
Marcotte R, Sayad A, Iorio C, Moffat J, Neel BG. Abstract PR14: integrative functional genomics of breast cancer. Cancer Res. 2015;75:PR14-PR.
-
(2015)
Cancer Res
, vol.75
-
-
Marcotte, R.1
Sayad, A.2
Iorio, C.3
Moffat, J.4
Neel, B.G.5
-
2
-
-
84875709263
-
Targeting insulin and insulin-like growth factor signaling in breast cancer
-
PID: 23054135
-
Yang Y, Yee D. Targeting insulin and insulin-like growth factor signaling in breast cancer. J Mammary Gland Biol Neoplasia. 2012;17:251–61.
-
(2012)
J Mammary Gland Biol Neoplasia
, vol.17
, pp. 251-261
-
-
Yang, Y.1
Yee, D.2
-
3
-
-
84992761080
-
The immunobiology of myeloid-derived suppressor cells in cancer
-
Motallebnezhad M, Jadidi-Niaragh F, Qamsari ES, Bagheri S, Gharibi T, Yousefi M. The immunobiology of myeloid-derived suppressor cells in cancer. Tumor Biol. 2015:1–20.
-
(2015)
Tumor Biol
, pp. 1-20
-
-
Motallebnezhad, M.1
Jadidi-Niaragh, F.2
Qamsari, E.S.3
Bagheri, S.4
Gharibi, T.5
Yousefi, M.6
-
4
-
-
43249123378
-
Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics
-
PID: 18437204
-
Garcia-Closas M, Hall P, Nevanlinna H, Pooley K, Morrison J, Richesson DA, et al. Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genet. 2008;4:e1000054.
-
(2008)
PLoS Genet
, vol.4
-
-
Garcia-Closas, M.1
Hall, P.2
Nevanlinna, H.3
Pooley, K.4
Morrison, J.5
Richesson, D.A.6
-
5
-
-
84857635199
-
Pharmacodynamic modeling of sequence-dependent antitumor activity of insulin-like growth factor blockade and gemcitabine
-
COI: 1:CAS:528:DC%2BC38XjtVGgsro%3D, PID: 22101930
-
Khatri A, Brundage RC, Hull JM, Williams BW, Yee D, Kirstein MN. Pharmacodynamic modeling of sequence-dependent antitumor activity of insulin-like growth factor blockade and gemcitabine. AAPS J. 2012;14:1–9.
-
(2012)
AAPS J
, vol.14
, pp. 1-9
-
-
Khatri, A.1
Brundage, R.C.2
Hull, J.M.3
Williams, B.W.4
Yee, D.5
Kirstein, M.N.6
-
6
-
-
35148837581
-
Mechanisms of disease: signaling of the insulin-like growth factor 1 receptor pathway—therapeutic perspectives in cancer
-
COI: 1:CAS:528:DC%2BD2sXhtV2isLfE, PID: 17898809
-
Tao Y, Pinzi V, Bourhis J, Deutsch E. Mechanisms of disease: signaling of the insulin-like growth factor 1 receptor pathway—therapeutic perspectives in cancer. Nat Clin Pract Oncol. 2007;4:591–602.
-
(2007)
Nat Clin Pract Oncol
, vol.4
, pp. 591-602
-
-
Tao, Y.1
Pinzi, V.2
Bourhis, J.3
Deutsch, E.4
-
7
-
-
84930661622
-
Role of IGF1R in breast cancer subtypes, stemness, and lineage differentiation
-
Farabaugh SM, Boone DN, Lee AV. Role of IGF1R in breast cancer subtypes, stemness, and lineage differentiation. Front Endocrinol. 2015;6.
-
(2015)
Front Endocrinol
, pp. 6
-
-
Farabaugh, S.M.1
Boone, D.N.2
Lee, A.V.3
-
8
-
-
57749089652
-
Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival
-
COI: 1:CAS:528:DC%2BD1cXhsV2itL7K, PID: 19074892
-
Law JH, Habibi G, Hu K, Masoudi H, Wang MY, Stratford AL, et al. Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival. Cancer Res. 2008;68:10238–46.
-
(2008)
Cancer Res
, vol.68
, pp. 10238-10246
-
-
Law, J.H.1
Habibi, G.2
Hu, K.3
Masoudi, H.4
Wang, M.Y.5
Stratford, A.L.6
-
9
-
-
84901002030
-
The emerging role of insulin and insulin-like growth factor signaling in cancer stem cells
-
Malaguarnera R, Belfiore A. The emerging role of insulin and insulin-like growth factor signaling in cancer stem cells. Front Endocrinol (Lausanne). 2014;5.
-
(2014)
Front Endocrinol (Lausanne)
, pp. 5
-
-
Malaguarnera, R.1
Belfiore, A.2
-
10
-
-
84924957491
-
FAK activation is required for IGF1R-mediated regulation of EMT, migration, and invasion in mesenchymal triple negative breast cancer cells
-
PID: 25749031
-
Taliaferro-Smith L, Oberlick E, Liu T, McGlothen T, Alcaide T, Tobin R, et al. FAK activation is required for IGF1R-mediated regulation of EMT, migration, and invasion in mesenchymal triple negative breast cancer cells. Oncotarget. 2015;6:4757.
-
(2015)
Oncotarget
, vol.6
, pp. 4757
-
-
Taliaferro-Smith, L.1
Oberlick, E.2
Liu, T.3
McGlothen, T.4
Alcaide, T.5
Tobin, R.6
-
11
-
-
0030738695
-
Insulin-like growth factor 1 (IGF-1) alters drug sensitivity of HBL100 human breast cancer cells by inhibition of apoptosis induced by diverse anticancer drugs
-
COI: 1:CAS:528:DyaK2sXktlSis7s%3D, PID: 9205078
-
Dunn SE, Hardman RA, Kari FW, Barrett JC. Insulin-like growth factor 1 (IGF-1) alters drug sensitivity of HBL100 human breast cancer cells by inhibition of apoptosis induced by diverse anticancer drugs. Cancer Res. 1997;57:2687–93.
-
(1997)
Cancer Res
, vol.57
, pp. 2687-2693
-
-
Dunn, S.E.1
Hardman, R.A.2
Kari, F.W.3
Barrett, J.C.4
-
12
-
-
84939134492
-
Insulin-like growth factor (IGF) signaling in tumorigenesis and the development of cancer drug resistance
-
COI: 1:CAS:528:DC%2BC28XjtFKrtLg%3D, PID: 25984556
-
Denduluri SK, Idowu O, Wang Z, Liao Z, Yan Z, Mohammed MK, et al. Insulin-like growth factor (IGF) signaling in tumorigenesis and the development of cancer drug resistance. Genes Dis. 2015;2:13–25.
-
(2015)
Genes Dis
, vol.2
, pp. 13-25
-
-
Denduluri, S.K.1
Idowu, O.2
Wang, Z.3
Liao, Z.4
Yan, Z.5
Mohammed, M.K.6
-
13
-
-
84908326985
-
Breast cancer stem cells, EMT and therapeutic targets
-
COI: 1:CAS:528:DC%2BC2cXhs1Gnu7bF, PID: 25261721
-
Kotiyal S, Bhattacharya S. Breast cancer stem cells, EMT and therapeutic targets. Biochem Biophys Res Commun. 2014;453:112–6.
-
(2014)
Biochem Biophys Res Commun
, vol.453
, pp. 112-116
-
-
Kotiyal, S.1
Bhattacharya, S.2
-
14
-
-
84905097153
-
Insulin-like growth factor receptor-1 (IGF-IR) as a target for prostate cancer therapy
-
COI: 1:CAS:528:DC%2BC2cXht1KisL3N, PID: 24414227
-
Wu J, Yu E. Insulin-like growth factor receptor-1 (IGF-IR) as a target for prostate cancer therapy. Cancer Metastasis Rev. 2014;33:607–17.
-
(2014)
Cancer Metastasis Rev
, vol.33
, pp. 607-617
-
-
Wu, J.1
Yu, E.2
-
15
-
-
84857920393
-
Insulin-like growth factor receptor (IGF-1R) in breast cancer subtypes
-
COI: 1:CAS:528:DC%2BC38XitVSktrw%3D, PID: 21574055
-
Yerushalmi R, Gelmon KA, Leung S, Gao D, Cheang M, Pollak M, et al. Insulin-like growth factor receptor (IGF-1R) in breast cancer subtypes. Breast Cancer Res Treat. 2012;132:131–42.
-
(2012)
Breast Cancer Res Treat
, vol.132
, pp. 131-142
-
-
Yerushalmi, R.1
Gelmon, K.A.2
Leung, S.3
Gao, D.4
Cheang, M.5
Pollak, M.6
-
16
-
-
84903937903
-
Positive expression of insulin-like growth factor-1 receptor is associated with a positive hormone receptor status and a favorable prognosis in breast cancer
-
PID: 25013431
-
Shin S-J, Gong G, Lee HJ, Kang J, Bae YK, Lee A, et al. Positive expression of insulin-like growth factor-1 receptor is associated with a positive hormone receptor status and a favorable prognosis in breast cancer. J Breast Cancer. 2014;17:113–20.
-
(2014)
J Breast Cancer
, vol.17
, pp. 113-120
-
-
Shin, S.-J.1
Gong, G.2
Lee, H.J.3
Kang, J.4
Bae, Y.K.5
Lee, A.6
-
17
-
-
84899132878
-
miR-630 targets IGF1R to regulate response to HER-targeting drugs and overall cancer cell progression in HER2 over-expressing breast cancer
-
Corcoran C, Rani S, Breslin S, Gogarty M, Ghobrial IM, Crown J, et al. miR-630 targets IGF1R to regulate response to HER-targeting drugs and overall cancer cell progression in HER2 over-expressing breast cancer. Mol Cancer. 2014;13:1.
-
(2014)
Mol Cancer
, vol.13
, pp. 1
-
-
Corcoran, C.1
Rani, S.2
Breslin, S.3
Gogarty, M.4
Ghobrial, I.M.5
Crown, J.6
-
18
-
-
84997599941
-
Abstract P4-15-20: insulin-like growth factor receptor-1 (IGF-1R) expression is highly correlated with HER2 amplification on circulating epithelial tumor cells (CETCs) in breast cancer-this may be the reason for resistance to trastuzumab
-
Zimon D, Pizon M, Pachmann U, Pachmann K. Abstract P4-15-20: insulin-like growth factor receptor-1 (IGF-1R) expression is highly correlated with HER2 amplification on circulating epithelial tumor cells (CETCs) in breast cancer-this may be the reason for resistance to trastuzumab. Cancer Res. 2015;75:P4-15-20.
-
(2015)
Cancer Res
, vol.75
, pp. 15-20
-
-
Zimon, D.1
Pizon, M.2
Pachmann, U.3
Pachmann, K.4
-
19
-
-
84898601995
-
Epigenetic silencing of miR-375 induces trastuzumab resistance in HER2-positive breast cancer by targeting IGF1R
-
Ye X-M, Zhu H-Y, Bai W-D, Wang T, Wang L, Chen Y, et al. Epigenetic silencing of miR-375 induces trastuzumab resistance in HER2-positive breast cancer by targeting IGF1R. BMC Cancer. 2014;14:1.
-
(2014)
BMC Cancer
, vol.14
, pp. 1
-
-
Ye, X.-M.1
Zhu, H.-Y.2
Bai, W.-D.3
Wang, T.4
Wang, L.5
Chen, Y.6
-
20
-
-
84919714378
-
Insulin-like growth factor-1 receptor signaling increases the invasive potential of human epidermal growth factor receptor 2-overexpressing breast cancer cells via Src-focal adhesion kinase and forkhead box protein M1
-
PID: 25391374
-
Sanabria-Figueroa E, Donnelly SM, Foy KC, Buss MC, Castellino RC, Paplomata E, et al. Insulin-like growth factor-1 receptor signaling increases the invasive potential of human epidermal growth factor receptor 2-overexpressing breast cancer cells via Src-focal adhesion kinase and forkhead box protein M1. Mol Pharmacol. 2015;87:150–61.
-
(2015)
Mol Pharmacol
, vol.87
, pp. 150-161
-
-
Sanabria-Figueroa, E.1
Donnelly, S.M.2
Foy, K.C.3
Buss, M.C.4
Castellino, R.C.5
Paplomata, E.6
-
21
-
-
84892598423
-
Superior antitumor activity of a novel bispecific antibody cotargeting human epidermal growth factor receptor 2 and type I insulin-like growth factor receptor
-
COI: 1:CAS:528:DC%2BC2cXnsFSqsg%3D%3D, PID: 24227890
-
Chen C, Zhang Y, Zhang Y, Li J, Tsao SW, Zhang M-Y. Superior antitumor activity of a novel bispecific antibody cotargeting human epidermal growth factor receptor 2 and type I insulin-like growth factor receptor. Mol Cancer Ther. 2014;13:90–100.
-
(2014)
Mol Cancer Ther
, vol.13
, pp. 90-100
-
-
Chen, C.1
Zhang, Y.2
Zhang, Y.3
Li, J.4
Tsao, S.W.5
Zhang, M.-Y.6
-
22
-
-
80052397117
-
Potent anti-proliferative effects of metformin on trastuzumab-resistant breast cancer cells via inhibition of erbB2/IGF-1 receptor interactions
-
COI: 1:CAS:528:DC%2BC38XnvFKhtw%3D%3D, PID: 21862872
-
Liu B, Fan Z, Edgerton SM, Yang X, Lind SE, Thor AD. Potent anti-proliferative effects of metformin on trastuzumab-resistant breast cancer cells via inhibition of erbB2/IGF-1 receptor interactions. Cell Cycle. 2011;10:2959–66.
-
(2011)
Cell Cycle
, vol.10
, pp. 2959-2966
-
-
Liu, B.1
Fan, Z.2
Edgerton, S.M.3
Yang, X.4
Lind, S.E.5
Thor, A.D.6
-
23
-
-
84876729230
-
Targeting cytokines: production and characterization of anti-TNF-α scFvs by phage display technology
-
COI: 1:CAS:528:DC%2BC3sXos1KhtLc%3D, PID: 23432628
-
Abdolalizadeh J, Nouri M, Majidi Zolbanin J, Barzegari A, Baradaran B, Barar J, et al. Targeting cytokines: production and characterization of anti-TNF-α scFvs by phage display technology. Curr Pharm Des. 2013;19:2839–47.
-
(2013)
Curr Pharm Des
, vol.19
, pp. 2839-2847
-
-
Abdolalizadeh, J.1
Nouri, M.2
Majidi Zolbanin, J.3
Barzegari, A.4
Baradaran, B.5
Barar, J.6
-
24
-
-
84954186754
-
Design and construction of immune phage antibody library against tetanus neurotoxin: production of single chain antibody fragments
-
COI: 1:CAS:528:DC%2BC28XjsFKrsrk%3D, PID: 27472865
-
Sadreddini S, Seifi-Najmi M, Ghasemi B, Kafil HS, Alinejad V, Sadreddini S, et al. Design and construction of immune phage antibody library against tetanus neurotoxin: production of single chain antibody fragments. Human Antibodies. 2015;23:73–9.
-
(2015)
Human Antibodies
, vol.23
, pp. 73-79
-
-
Sadreddini, S.1
Seifi-Najmi, M.2
Ghasemi, B.3
Kafil, H.S.4
Alinejad, V.5
Sadreddini, S.6
-
25
-
-
84913533385
-
Induction of anti-proliferative and apoptotic effects by anti-IL-25 receptor single chain antibodies in breast cancer cells
-
COI: 1:CAS:528:DC%2BC2cXhvVanu7zK, PID: 25466271
-
Younesi V, Nejatollahi F. Induction of anti-proliferative and apoptotic effects by anti-IL-25 receptor single chain antibodies in breast cancer cells. Int Immunopharmacol. 2014;23:624–32.
-
(2014)
Int Immunopharmacol
, vol.23
, pp. 624-632
-
-
Younesi, V.1
Nejatollahi, F.2
-
26
-
-
84893829723
-
Antiproliferative and apoptotic effects of a specific antiprostate stem cell single chain antibody on human prostate cancer cells
-
Nejatollahi F, Abdi S, Asgharpour M. Antiproliferative and apoptotic effects of a specific antiprostate stem cell single chain antibody on human prostate cancer cells. J Oncol. 2013;2013.
-
(2013)
J Oncol
, pp. 2013
-
-
Nejatollahi, F.1
Abdi, S.2
Asgharpour, M.3
-
27
-
-
0037285971
-
Growth factor receptors in breast cancer: potential for therapeutic intervention
-
COI: 1:CAS:528:DC%2BD3sXhvVyqsb0%3D, PID: 12604728
-
Nahta R, Hortobagyi GN, Esteva FJ. Growth factor receptors in breast cancer: potential for therapeutic intervention. Oncologist. 2003;8:5–17.
-
(2003)
Oncologist
, vol.8
, pp. 5-17
-
-
Nahta, R.1
Hortobagyi, G.N.2
Esteva, F.J.3
-
28
-
-
9144234724
-
A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo
-
COI: 1:CAS:528:DC%2BD3sXhtVSqtbvL, PID: 14695208
-
Burtrum D, Zhu Z, Lu D, Anderson DM, Prewett M, Pereira DS, et al. A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo. Cancer Res. 2003;63:8912–21.
-
(2003)
Cancer Res
, vol.63
, pp. 8912-8921
-
-
Burtrum, D.1
Zhu, Z.2
Lu, D.3
Anderson, D.M.4
Prewett, M.5
Pereira, D.S.6
-
29
-
-
84926442274
-
Insulin-like growth factor system in cancer: novel targeted therapies
-
Brahmkhatri VP, Prasanna C, Atreya HS. Insulin-like growth factor system in cancer: novel targeted therapies. Biomed Res Int. 2015;2015.
-
(2015)
Biomed Res Int
, pp. 2015
-
-
Brahmkhatri, V.P.1
Prasanna, C.2
Atreya, H.S.3
-
30
-
-
79960712070
-
Highly efficient production of anti-HER2 scFv antibody variant for targeting breast cancer cells
-
COI: 1:CAS:528:DC%2BC3MXovFCmtr0%3D, PID: 21538107
-
Sommaruga S, Lombardi A, Salvadè A, Mazzucchelli S, Corsi F, Galeffi P, et al. Highly efficient production of anti-HER2 scFv antibody variant for targeting breast cancer cells. Appl Microbiol Biotechnol. 2011;91:613–21.
-
(2011)
Appl Microbiol Biotechnol
, vol.91
, pp. 613-621
-
-
Sommaruga, S.1
Lombardi, A.2
Salvadè, A.3
Mazzucchelli, S.4
Corsi, F.5
Galeffi, P.6
-
31
-
-
77957370161
-
Development of an EGFRvIII specific recombinant antibody
-
PID: 20925961
-
Gupta P, Han S-Y, Holgado-Madruga M, Mitra SS, Li G, Nitta RT, et al. Development of an EGFRvIII specific recombinant antibody. BMC Biotechnol. 2010;10:72.
-
(2010)
BMC Biotechnol
, vol.10
, pp. 72
-
-
Gupta, P.1
Han, S.-Y.2
Holgado-Madruga, M.3
Mitra, S.S.4
Li, G.5
Nitta, R.T.6
-
32
-
-
54049118086
-
Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake
-
COI: 1:CAS:528:DC%2BD1cXhtFSms7jL, PID: 18790743
-
Shang Y, Mao Y, Batson J, Scales SJ, Phillips G, Lackner MR, et al. Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake. Mol Cancer Ther. 2008;7:2599–608.
-
(2008)
Mol Cancer Ther
, vol.7
, pp. 2599-2608
-
-
Shang, Y.1
Mao, Y.2
Batson, J.3
Scales, S.J.4
Phillips, G.5
Lackner, M.R.6
-
33
-
-
0042515293
-
An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation
-
COI: 1:CAS:528:DC%2BD3sXms12nsbk%3D, PID: 12941837
-
Maloney EK, McLaughlin JL, Dagdigian NE, Garrett LM, Connors KM, Zhou X-M, et al. An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation. Cancer Res. 2003;63:5073–83.
-
(2003)
Cancer Res
, vol.63
, pp. 5073-5083
-
-
Maloney, E.K.1
McLaughlin, J.L.2
Dagdigian, N.E.3
Garrett, L.M.4
Connors, K.M.5
Zhou, X.-M.6
-
34
-
-
84860014256
-
Treatment of breast cancer cells by IGF1R tyrosine kinase inhibitor combined with conventional systemic drugs
-
COI: 1:CAS:528:DC%2BC38Xms1Sqtb8%3D, PID: 22493363
-
Hartog H, Van Der Graaf W, Boezen H, Wesseling J. Treatment of breast cancer cells by IGF1R tyrosine kinase inhibitor combined with conventional systemic drugs. Anticancer Res. 2012;32:1309–18.
-
(2012)
Anticancer Res
, vol.32
, pp. 1309-1318
-
-
Hartog, H.1
Van Der Graaf, W.2
Boezen, H.3
Wesseling, J.4
-
35
-
-
78650372147
-
Inhibition of IGF1R activity enhances response to trastuzumab in HER-2-positive breast cancer cells
-
COI: 1:STN:280:DC%2BC3M%2FkvFKksA%3D%3D, PID: 20647220
-
Browne B, Crown J, Venkatesan N, Duffy M, Clynes M, Slamon D, et al. Inhibition of IGF1R activity enhances response to trastuzumab in HER-2-positive breast cancer cells. Ann Oncol. 2011;22:68–73.
-
(2011)
Ann Oncol
, vol.22
, pp. 68-73
-
-
Browne, B.1
Crown, J.2
Venkatesan, N.3
Duffy, M.4
Clynes, M.5
Slamon, D.6
-
36
-
-
34249672864
-
Trastuzumab: triumphs and tribulations
-
COI: 1:CAS:528:DC%2BD2sXlslCqsbY%3D, PID: 17530017
-
Nahta R, Esteva F. Trastuzumab: triumphs and tribulations. Oncogene. 2007;26:3637–43.
-
(2007)
Oncogene
, vol.26
, pp. 3637-3643
-
-
Nahta, R.1
Esteva, F.2
-
37
-
-
28244432561
-
Insulin-like growth factor-I receptor/human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells
-
COI: 1:CAS:528:DC%2BD2MXht1KjsrrI, PID: 16322262
-
Nahta R, Yuan LX, Zhang B, Kobayashi R, Esteva FJ. Insulin-like growth factor-I receptor/human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells. Cancer Res. 2005;65:11118–28.
-
(2005)
Cancer Res
, vol.65
, pp. 11118-11128
-
-
Nahta, R.1
Yuan, L.X.2
Zhang, B.3
Kobayashi, R.4
Esteva, F.J.5
|