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Volumn 37, Issue 11, 2016, Pages 14841-14850

Antiproliferative and apoptotic effects of a specific anti-insulin-like growth factor I receptor single chain antibody on breast cancer cells

Author keywords

Breast cancer; Insulin like growth factor I receptor; Phage display; Single chain fragment variable (scFv) antibodies; Trastuzumab

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR 2; EPITOPE; LIPOCORTIN 5; SINGLE CHAIN FRAGMENT VARIABLE ANTIBODY; SOMATOMEDIN C RECEPTOR; TRASTUZUMAB; ERBB2 PROTEIN, HUMAN; MONOCLONAL ANTIBODY;

EID: 84988375052     PISSN: 10104283     EISSN: 14230380     Source Type: Journal    
DOI: 10.1007/s13277-016-5323-4     Document Type: Article
Times cited : (7)

References (37)
  • 1
  • 2
    • 84875709263 scopus 로고    scopus 로고
    • Targeting insulin and insulin-like growth factor signaling in breast cancer
    • PID: 23054135
    • Yang Y, Yee D. Targeting insulin and insulin-like growth factor signaling in breast cancer. J Mammary Gland Biol Neoplasia. 2012;17:251–61.
    • (2012) J Mammary Gland Biol Neoplasia , vol.17 , pp. 251-261
    • Yang, Y.1    Yee, D.2
  • 4
    • 43249123378 scopus 로고    scopus 로고
    • Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics
    • PID: 18437204
    • Garcia-Closas M, Hall P, Nevanlinna H, Pooley K, Morrison J, Richesson DA, et al. Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. PLoS Genet. 2008;4:e1000054.
    • (2008) PLoS Genet , vol.4
    • Garcia-Closas, M.1    Hall, P.2    Nevanlinna, H.3    Pooley, K.4    Morrison, J.5    Richesson, D.A.6
  • 5
    • 84857635199 scopus 로고    scopus 로고
    • Pharmacodynamic modeling of sequence-dependent antitumor activity of insulin-like growth factor blockade and gemcitabine
    • COI: 1:CAS:528:DC%2BC38XjtVGgsro%3D, PID: 22101930
    • Khatri A, Brundage RC, Hull JM, Williams BW, Yee D, Kirstein MN. Pharmacodynamic modeling of sequence-dependent antitumor activity of insulin-like growth factor blockade and gemcitabine. AAPS J. 2012;14:1–9.
    • (2012) AAPS J , vol.14 , pp. 1-9
    • Khatri, A.1    Brundage, R.C.2    Hull, J.M.3    Williams, B.W.4    Yee, D.5    Kirstein, M.N.6
  • 6
    • 35148837581 scopus 로고    scopus 로고
    • Mechanisms of disease: signaling of the insulin-like growth factor 1 receptor pathway—therapeutic perspectives in cancer
    • COI: 1:CAS:528:DC%2BD2sXhtV2isLfE, PID: 17898809
    • Tao Y, Pinzi V, Bourhis J, Deutsch E. Mechanisms of disease: signaling of the insulin-like growth factor 1 receptor pathway—therapeutic perspectives in cancer. Nat Clin Pract Oncol. 2007;4:591–602.
    • (2007) Nat Clin Pract Oncol , vol.4 , pp. 591-602
    • Tao, Y.1    Pinzi, V.2    Bourhis, J.3    Deutsch, E.4
  • 7
    • 84930661622 scopus 로고    scopus 로고
    • Role of IGF1R in breast cancer subtypes, stemness, and lineage differentiation
    • Farabaugh SM, Boone DN, Lee AV. Role of IGF1R in breast cancer subtypes, stemness, and lineage differentiation. Front Endocrinol. 2015;6.
    • (2015) Front Endocrinol , pp. 6
    • Farabaugh, S.M.1    Boone, D.N.2    Lee, A.V.3
  • 8
    • 57749089652 scopus 로고    scopus 로고
    • Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival
    • COI: 1:CAS:528:DC%2BD1cXhsV2itL7K, PID: 19074892
    • Law JH, Habibi G, Hu K, Masoudi H, Wang MY, Stratford AL, et al. Phosphorylated insulin-like growth factor-i/insulin receptor is present in all breast cancer subtypes and is related to poor survival. Cancer Res. 2008;68:10238–46.
    • (2008) Cancer Res , vol.68 , pp. 10238-10246
    • Law, J.H.1    Habibi, G.2    Hu, K.3    Masoudi, H.4    Wang, M.Y.5    Stratford, A.L.6
  • 9
    • 84901002030 scopus 로고    scopus 로고
    • The emerging role of insulin and insulin-like growth factor signaling in cancer stem cells
    • Malaguarnera R, Belfiore A. The emerging role of insulin and insulin-like growth factor signaling in cancer stem cells. Front Endocrinol (Lausanne). 2014;5.
    • (2014) Front Endocrinol (Lausanne) , pp. 5
    • Malaguarnera, R.1    Belfiore, A.2
  • 10
    • 84924957491 scopus 로고    scopus 로고
    • FAK activation is required for IGF1R-mediated regulation of EMT, migration, and invasion in mesenchymal triple negative breast cancer cells
    • PID: 25749031
    • Taliaferro-Smith L, Oberlick E, Liu T, McGlothen T, Alcaide T, Tobin R, et al. FAK activation is required for IGF1R-mediated regulation of EMT, migration, and invasion in mesenchymal triple negative breast cancer cells. Oncotarget. 2015;6:4757.
    • (2015) Oncotarget , vol.6 , pp. 4757
    • Taliaferro-Smith, L.1    Oberlick, E.2    Liu, T.3    McGlothen, T.4    Alcaide, T.5    Tobin, R.6
  • 11
    • 0030738695 scopus 로고    scopus 로고
    • Insulin-like growth factor 1 (IGF-1) alters drug sensitivity of HBL100 human breast cancer cells by inhibition of apoptosis induced by diverse anticancer drugs
    • COI: 1:CAS:528:DyaK2sXktlSis7s%3D, PID: 9205078
    • Dunn SE, Hardman RA, Kari FW, Barrett JC. Insulin-like growth factor 1 (IGF-1) alters drug sensitivity of HBL100 human breast cancer cells by inhibition of apoptosis induced by diverse anticancer drugs. Cancer Res. 1997;57:2687–93.
    • (1997) Cancer Res , vol.57 , pp. 2687-2693
    • Dunn, S.E.1    Hardman, R.A.2    Kari, F.W.3    Barrett, J.C.4
  • 12
    • 84939134492 scopus 로고    scopus 로고
    • Insulin-like growth factor (IGF) signaling in tumorigenesis and the development of cancer drug resistance
    • COI: 1:CAS:528:DC%2BC28XjtFKrtLg%3D, PID: 25984556
    • Denduluri SK, Idowu O, Wang Z, Liao Z, Yan Z, Mohammed MK, et al. Insulin-like growth factor (IGF) signaling in tumorigenesis and the development of cancer drug resistance. Genes Dis. 2015;2:13–25.
    • (2015) Genes Dis , vol.2 , pp. 13-25
    • Denduluri, S.K.1    Idowu, O.2    Wang, Z.3    Liao, Z.4    Yan, Z.5    Mohammed, M.K.6
  • 13
    • 84908326985 scopus 로고    scopus 로고
    • Breast cancer stem cells, EMT and therapeutic targets
    • COI: 1:CAS:528:DC%2BC2cXhs1Gnu7bF, PID: 25261721
    • Kotiyal S, Bhattacharya S. Breast cancer stem cells, EMT and therapeutic targets. Biochem Biophys Res Commun. 2014;453:112–6.
    • (2014) Biochem Biophys Res Commun , vol.453 , pp. 112-116
    • Kotiyal, S.1    Bhattacharya, S.2
  • 14
    • 84905097153 scopus 로고    scopus 로고
    • Insulin-like growth factor receptor-1 (IGF-IR) as a target for prostate cancer therapy
    • COI: 1:CAS:528:DC%2BC2cXht1KisL3N, PID: 24414227
    • Wu J, Yu E. Insulin-like growth factor receptor-1 (IGF-IR) as a target for prostate cancer therapy. Cancer Metastasis Rev. 2014;33:607–17.
    • (2014) Cancer Metastasis Rev , vol.33 , pp. 607-617
    • Wu, J.1    Yu, E.2
  • 15
    • 84857920393 scopus 로고    scopus 로고
    • Insulin-like growth factor receptor (IGF-1R) in breast cancer subtypes
    • COI: 1:CAS:528:DC%2BC38XitVSktrw%3D, PID: 21574055
    • Yerushalmi R, Gelmon KA, Leung S, Gao D, Cheang M, Pollak M, et al. Insulin-like growth factor receptor (IGF-1R) in breast cancer subtypes. Breast Cancer Res Treat. 2012;132:131–42.
    • (2012) Breast Cancer Res Treat , vol.132 , pp. 131-142
    • Yerushalmi, R.1    Gelmon, K.A.2    Leung, S.3    Gao, D.4    Cheang, M.5    Pollak, M.6
  • 16
    • 84903937903 scopus 로고    scopus 로고
    • Positive expression of insulin-like growth factor-1 receptor is associated with a positive hormone receptor status and a favorable prognosis in breast cancer
    • PID: 25013431
    • Shin S-J, Gong G, Lee HJ, Kang J, Bae YK, Lee A, et al. Positive expression of insulin-like growth factor-1 receptor is associated with a positive hormone receptor status and a favorable prognosis in breast cancer. J Breast Cancer. 2014;17:113–20.
    • (2014) J Breast Cancer , vol.17 , pp. 113-120
    • Shin, S.-J.1    Gong, G.2    Lee, H.J.3    Kang, J.4    Bae, Y.K.5    Lee, A.6
  • 17
    • 84899132878 scopus 로고    scopus 로고
    • miR-630 targets IGF1R to regulate response to HER-targeting drugs and overall cancer cell progression in HER2 over-expressing breast cancer
    • Corcoran C, Rani S, Breslin S, Gogarty M, Ghobrial IM, Crown J, et al. miR-630 targets IGF1R to regulate response to HER-targeting drugs and overall cancer cell progression in HER2 over-expressing breast cancer. Mol Cancer. 2014;13:1.
    • (2014) Mol Cancer , vol.13 , pp. 1
    • Corcoran, C.1    Rani, S.2    Breslin, S.3    Gogarty, M.4    Ghobrial, I.M.5    Crown, J.6
  • 18
    • 84997599941 scopus 로고    scopus 로고
    • Abstract P4-15-20: insulin-like growth factor receptor-1 (IGF-1R) expression is highly correlated with HER2 amplification on circulating epithelial tumor cells (CETCs) in breast cancer-this may be the reason for resistance to trastuzumab
    • Zimon D, Pizon M, Pachmann U, Pachmann K. Abstract P4-15-20: insulin-like growth factor receptor-1 (IGF-1R) expression is highly correlated with HER2 amplification on circulating epithelial tumor cells (CETCs) in breast cancer-this may be the reason for resistance to trastuzumab. Cancer Res. 2015;75:P4-15-20.
    • (2015) Cancer Res , vol.75 , pp. 15-20
    • Zimon, D.1    Pizon, M.2    Pachmann, U.3    Pachmann, K.4
  • 19
    • 84898601995 scopus 로고    scopus 로고
    • Epigenetic silencing of miR-375 induces trastuzumab resistance in HER2-positive breast cancer by targeting IGF1R
    • Ye X-M, Zhu H-Y, Bai W-D, Wang T, Wang L, Chen Y, et al. Epigenetic silencing of miR-375 induces trastuzumab resistance in HER2-positive breast cancer by targeting IGF1R. BMC Cancer. 2014;14:1.
    • (2014) BMC Cancer , vol.14 , pp. 1
    • Ye, X.-M.1    Zhu, H.-Y.2    Bai, W.-D.3    Wang, T.4    Wang, L.5    Chen, Y.6
  • 20
    • 84919714378 scopus 로고    scopus 로고
    • Insulin-like growth factor-1 receptor signaling increases the invasive potential of human epidermal growth factor receptor 2-overexpressing breast cancer cells via Src-focal adhesion kinase and forkhead box protein M1
    • PID: 25391374
    • Sanabria-Figueroa E, Donnelly SM, Foy KC, Buss MC, Castellino RC, Paplomata E, et al. Insulin-like growth factor-1 receptor signaling increases the invasive potential of human epidermal growth factor receptor 2-overexpressing breast cancer cells via Src-focal adhesion kinase and forkhead box protein M1. Mol Pharmacol. 2015;87:150–61.
    • (2015) Mol Pharmacol , vol.87 , pp. 150-161
    • Sanabria-Figueroa, E.1    Donnelly, S.M.2    Foy, K.C.3    Buss, M.C.4    Castellino, R.C.5    Paplomata, E.6
  • 21
    • 84892598423 scopus 로고    scopus 로고
    • Superior antitumor activity of a novel bispecific antibody cotargeting human epidermal growth factor receptor 2 and type I insulin-like growth factor receptor
    • COI: 1:CAS:528:DC%2BC2cXnsFSqsg%3D%3D, PID: 24227890
    • Chen C, Zhang Y, Zhang Y, Li J, Tsao SW, Zhang M-Y. Superior antitumor activity of a novel bispecific antibody cotargeting human epidermal growth factor receptor 2 and type I insulin-like growth factor receptor. Mol Cancer Ther. 2014;13:90–100.
    • (2014) Mol Cancer Ther , vol.13 , pp. 90-100
    • Chen, C.1    Zhang, Y.2    Zhang, Y.3    Li, J.4    Tsao, S.W.5    Zhang, M.-Y.6
  • 22
    • 80052397117 scopus 로고    scopus 로고
    • Potent anti-proliferative effects of metformin on trastuzumab-resistant breast cancer cells via inhibition of erbB2/IGF-1 receptor interactions
    • COI: 1:CAS:528:DC%2BC38XnvFKhtw%3D%3D, PID: 21862872
    • Liu B, Fan Z, Edgerton SM, Yang X, Lind SE, Thor AD. Potent anti-proliferative effects of metformin on trastuzumab-resistant breast cancer cells via inhibition of erbB2/IGF-1 receptor interactions. Cell Cycle. 2011;10:2959–66.
    • (2011) Cell Cycle , vol.10 , pp. 2959-2966
    • Liu, B.1    Fan, Z.2    Edgerton, S.M.3    Yang, X.4    Lind, S.E.5    Thor, A.D.6
  • 23
    • 84876729230 scopus 로고    scopus 로고
    • Targeting cytokines: production and characterization of anti-TNF-α scFvs by phage display technology
    • COI: 1:CAS:528:DC%2BC3sXos1KhtLc%3D, PID: 23432628
    • Abdolalizadeh J, Nouri M, Majidi Zolbanin J, Barzegari A, Baradaran B, Barar J, et al. Targeting cytokines: production and characterization of anti-TNF-α scFvs by phage display technology. Curr Pharm Des. 2013;19:2839–47.
    • (2013) Curr Pharm Des , vol.19 , pp. 2839-2847
    • Abdolalizadeh, J.1    Nouri, M.2    Majidi Zolbanin, J.3    Barzegari, A.4    Baradaran, B.5    Barar, J.6
  • 24
    • 84954186754 scopus 로고    scopus 로고
    • Design and construction of immune phage antibody library against tetanus neurotoxin: production of single chain antibody fragments
    • COI: 1:CAS:528:DC%2BC28XjsFKrsrk%3D, PID: 27472865
    • Sadreddini S, Seifi-Najmi M, Ghasemi B, Kafil HS, Alinejad V, Sadreddini S, et al. Design and construction of immune phage antibody library against tetanus neurotoxin: production of single chain antibody fragments. Human Antibodies. 2015;23:73–9.
    • (2015) Human Antibodies , vol.23 , pp. 73-79
    • Sadreddini, S.1    Seifi-Najmi, M.2    Ghasemi, B.3    Kafil, H.S.4    Alinejad, V.5    Sadreddini, S.6
  • 25
    • 84913533385 scopus 로고    scopus 로고
    • Induction of anti-proliferative and apoptotic effects by anti-IL-25 receptor single chain antibodies in breast cancer cells
    • COI: 1:CAS:528:DC%2BC2cXhvVanu7zK, PID: 25466271
    • Younesi V, Nejatollahi F. Induction of anti-proliferative and apoptotic effects by anti-IL-25 receptor single chain antibodies in breast cancer cells. Int Immunopharmacol. 2014;23:624–32.
    • (2014) Int Immunopharmacol , vol.23 , pp. 624-632
    • Younesi, V.1    Nejatollahi, F.2
  • 26
    • 84893829723 scopus 로고    scopus 로고
    • Antiproliferative and apoptotic effects of a specific antiprostate stem cell single chain antibody on human prostate cancer cells
    • Nejatollahi F, Abdi S, Asgharpour M. Antiproliferative and apoptotic effects of a specific antiprostate stem cell single chain antibody on human prostate cancer cells. J Oncol. 2013;2013.
    • (2013) J Oncol , pp. 2013
    • Nejatollahi, F.1    Abdi, S.2    Asgharpour, M.3
  • 27
    • 0037285971 scopus 로고    scopus 로고
    • Growth factor receptors in breast cancer: potential for therapeutic intervention
    • COI: 1:CAS:528:DC%2BD3sXhvVyqsb0%3D, PID: 12604728
    • Nahta R, Hortobagyi GN, Esteva FJ. Growth factor receptors in breast cancer: potential for therapeutic intervention. Oncologist. 2003;8:5–17.
    • (2003) Oncologist , vol.8 , pp. 5-17
    • Nahta, R.1    Hortobagyi, G.N.2    Esteva, F.J.3
  • 28
    • 9144234724 scopus 로고    scopus 로고
    • A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo
    • COI: 1:CAS:528:DC%2BD3sXhtVSqtbvL, PID: 14695208
    • Burtrum D, Zhu Z, Lu D, Anderson DM, Prewett M, Pereira DS, et al. A fully human monoclonal antibody to the insulin-like growth factor I receptor blocks ligand-dependent signaling and inhibits human tumor growth in vivo. Cancer Res. 2003;63:8912–21.
    • (2003) Cancer Res , vol.63 , pp. 8912-8921
    • Burtrum, D.1    Zhu, Z.2    Lu, D.3    Anderson, D.M.4    Prewett, M.5    Pereira, D.S.6
  • 29
    • 84926442274 scopus 로고    scopus 로고
    • Insulin-like growth factor system in cancer: novel targeted therapies
    • Brahmkhatri VP, Prasanna C, Atreya HS. Insulin-like growth factor system in cancer: novel targeted therapies. Biomed Res Int. 2015;2015.
    • (2015) Biomed Res Int , pp. 2015
    • Brahmkhatri, V.P.1    Prasanna, C.2    Atreya, H.S.3
  • 30
    • 79960712070 scopus 로고    scopus 로고
    • Highly efficient production of anti-HER2 scFv antibody variant for targeting breast cancer cells
    • COI: 1:CAS:528:DC%2BC3MXovFCmtr0%3D, PID: 21538107
    • Sommaruga S, Lombardi A, Salvadè A, Mazzucchelli S, Corsi F, Galeffi P, et al. Highly efficient production of anti-HER2 scFv antibody variant for targeting breast cancer cells. Appl Microbiol Biotechnol. 2011;91:613–21.
    • (2011) Appl Microbiol Biotechnol , vol.91 , pp. 613-621
    • Sommaruga, S.1    Lombardi, A.2    Salvadè, A.3    Mazzucchelli, S.4    Corsi, F.5    Galeffi, P.6
  • 32
    • 54049118086 scopus 로고    scopus 로고
    • Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake
    • COI: 1:CAS:528:DC%2BD1cXhtFSms7jL, PID: 18790743
    • Shang Y, Mao Y, Batson J, Scales SJ, Phillips G, Lackner MR, et al. Antixenograft tumor activity of a humanized anti-insulin-like growth factor-I receptor monoclonal antibody is associated with decreased AKT activation and glucose uptake. Mol Cancer Ther. 2008;7:2599–608.
    • (2008) Mol Cancer Ther , vol.7 , pp. 2599-2608
    • Shang, Y.1    Mao, Y.2    Batson, J.3    Scales, S.J.4    Phillips, G.5    Lackner, M.R.6
  • 33
    • 0042515293 scopus 로고    scopus 로고
    • An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation
    • COI: 1:CAS:528:DC%2BD3sXms12nsbk%3D, PID: 12941837
    • Maloney EK, McLaughlin JL, Dagdigian NE, Garrett LM, Connors KM, Zhou X-M, et al. An anti-insulin-like growth factor I receptor antibody that is a potent inhibitor of cancer cell proliferation. Cancer Res. 2003;63:5073–83.
    • (2003) Cancer Res , vol.63 , pp. 5073-5083
    • Maloney, E.K.1    McLaughlin, J.L.2    Dagdigian, N.E.3    Garrett, L.M.4    Connors, K.M.5    Zhou, X.-M.6
  • 34
    • 84860014256 scopus 로고    scopus 로고
    • Treatment of breast cancer cells by IGF1R tyrosine kinase inhibitor combined with conventional systemic drugs
    • COI: 1:CAS:528:DC%2BC38Xms1Sqtb8%3D, PID: 22493363
    • Hartog H, Van Der Graaf W, Boezen H, Wesseling J. Treatment of breast cancer cells by IGF1R tyrosine kinase inhibitor combined with conventional systemic drugs. Anticancer Res. 2012;32:1309–18.
    • (2012) Anticancer Res , vol.32 , pp. 1309-1318
    • Hartog, H.1    Van Der Graaf, W.2    Boezen, H.3    Wesseling, J.4
  • 35
    • 78650372147 scopus 로고    scopus 로고
    • Inhibition of IGF1R activity enhances response to trastuzumab in HER-2-positive breast cancer cells
    • COI: 1:STN:280:DC%2BC3M%2FkvFKksA%3D%3D, PID: 20647220
    • Browne B, Crown J, Venkatesan N, Duffy M, Clynes M, Slamon D, et al. Inhibition of IGF1R activity enhances response to trastuzumab in HER-2-positive breast cancer cells. Ann Oncol. 2011;22:68–73.
    • (2011) Ann Oncol , vol.22 , pp. 68-73
    • Browne, B.1    Crown, J.2    Venkatesan, N.3    Duffy, M.4    Clynes, M.5    Slamon, D.6
  • 36
    • 34249672864 scopus 로고    scopus 로고
    • Trastuzumab: triumphs and tribulations
    • COI: 1:CAS:528:DC%2BD2sXlslCqsbY%3D, PID: 17530017
    • Nahta R, Esteva F. Trastuzumab: triumphs and tribulations. Oncogene. 2007;26:3637–43.
    • (2007) Oncogene , vol.26 , pp. 3637-3643
    • Nahta, R.1    Esteva, F.2
  • 37
    • 28244432561 scopus 로고    scopus 로고
    • Insulin-like growth factor-I receptor/human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells
    • COI: 1:CAS:528:DC%2BD2MXht1KjsrrI, PID: 16322262
    • Nahta R, Yuan LX, Zhang B, Kobayashi R, Esteva FJ. Insulin-like growth factor-I receptor/human epidermal growth factor receptor 2 heterodimerization contributes to trastuzumab resistance of breast cancer cells. Cancer Res. 2005;65:11118–28.
    • (2005) Cancer Res , vol.65 , pp. 11118-11128
    • Nahta, R.1    Yuan, L.X.2    Zhang, B.3    Kobayashi, R.4    Esteva, F.J.5


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