Risk Factor Management and Atrial Fibrillation Clinics: Saving the Best for Last?

Heart Lung and Circulation

Volumn 26, Issue 9, 2017, Pages 990-997

  Mahajan, Rajiv ^a   Pathak, Rajeev K ^a,b   Thiyagarajah, Anand ^a   Lau, Dennis H ^a   Marchlinski, Francis E ^b   Dixit, Sanjay ^b   Day, John D ^c   Hendriks, Jeroen M L ^a   Carrington, Melinda ^d   Kalman, Jonathan M ^e   Sanders, Prashanthan ^a  

^a ROYAL ADELAIDE HOSPITAL   (Australia)

^b HOSPITAL OF THE UNIVERSITY OF PENNSYLVANIA   (United States)

^c INTERMOUNTAIN MEDICAL CENTER   (United States)

^d BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

^e UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

Atrial fibrillation; Atrial remodelling; Cardiovascular risk factors

Indexed keywords

ABLATION THERAPY; ANTICOAGULATION; ATRIAL FIBRILLATION; CARDIOMETABOLIC RISK; CARDIORESPIRATORY FITNESS; CARDIOVASCULAR MORTALITY; CARDIOVASCULAR RISK; DIABETES MELLITUS; HUMAN; HYPERTENSION; MORBIDITY; OBESITY; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SLEEP DISORDERED BREATHING; THROMBOEMBOLISM; WEIGHT REDUCTION; GLOBAL HEALTH; PATHOPHYSIOLOGY; PROCEDURES; RISK FACTOR; RISK MANAGEMENT; SURVIVAL RATE; TRENDS;

ATRIAL FIBRILLATION; GLOBAL HEALTH; HUMANS; MORBIDITY; RISK FACTORS; RISK MANAGEMENT; SURVIVAL RATE;

EID: 85021169794     PISSN: 14439506     EISSN: 14442892     Source Type: Journal    
DOI: 10.1016/j.hlc.2017.05.123     Document Type: Review

References (74)

1. Wattigney, W.A., Mensah, G.A., Croft, J.B., Increasing trends in hospitalization for atrial fibrillation in the United States, 1985 through 1999: implications for primary prevention. Circulation 108:6 (2003), 711–716.
2. Miyasaka, Y., Barnes, M.E., Bailey, K.R., Cha, S.S., Gersh, B.J., Seward, J.B., et al. Mortality trends in patients diagnosed with first atrial fibrillation: a 21-year community-based study. Journal of the American College of Cardiology 49:9 (2007), 986–992.
3. Kannel, W.B., Wolf, P.A., Benjamin, E.J., Levy, D., Prevalence, incidence, prognosis, and predisposing conditions for atrial fibrillation: population-based estimates. The American Journal of Cardiology 82:8A (1998), 2N–9N.
4. Chugh, S.S., Havmoeller, R., Narayanan, K., Singh, D., Rienstra, M., Benjamin, E.J., et al. Worldwide epidemiology of atrial fibrillation: a Global Burden of Disease 2010 Study. Circulation 129:8 (2014), 837–847.
5. Nabauer, M., Gerth, A., Limbourg, T., Schneider, S., Oeff, M., Kirchhof, P., et al. The Registry of the German Competence NETwork on Atrial Fibrillation: patient characteristics and initial management. Europace 11:4 (2009), 423–434.
6. Wijffels, M.C., Kirchhof, C.J., Dorland, R., Allessie, M.A., Atrial fibrillation begets atrial fibrillation: A study in awake chronically instrumented goats. Circulation 92:7 (1995), 1954–1968.
7. Tsang, T.S., Barnes, M.E., Miyasaka, Y., Cha, S.S., Bailey, K.R., Verzosa, G.C., et al. Obesity as a risk factor for the progression of paroxysmal to permanent atrial fibrillation: a longitudinal cohort study of 21 years. European Heart Journal 29:18 (2008), 2227–2233.
8. Teh, A.W., Kistler, P.M., Lee, G., Medi, C., Heck, P.M., Spence, S.J., et al. Long-term effects of catheter ablation for lone atrial fibrillation: progressive atrial electroanatomic substrate remodeling despite successful ablation. Heart rhythm: the official journal of the Heart Rhythm Society 9:4 (2012), 473–480.
9. Calkins, H., Kuck, K.H., Cappato, R., Brugada, J., Camm, A.J., Chen, S.A., et al. HRS/EHRA/ECAS expert consensus statement on catheter and surgical ablation of atrial fibrillation: recommendations for patient selection, procedural techniques, patient management and follow-up, definitions, endpoints, and research trial design: a report of the Heart Rhythm Society (HRS) Task Force on Catheter and Surgical Ablation of Atrial Fibrillation. Developed in partnership with the European Heart Rhythm Association (EHRA), a registered branch of the European Society of Cardiology (ESC) and the European Cardiac Arrhythmia Society (ECAS); and in collaboration with the American College of Cardiology (ACC), American Heart Association (AHA), the Asia Pacific Heart Rhythm Society (APHRS), and the Society of Thoracic Surgeons (STS). Endorsed by the governing bodies of the American College of Cardiology Foundation, the American Heart Association, the European Cardiac Arrhythmia Society, the European Heart Rhythm Association, the Society of Thoracic Surgeons, the Asia Pacific Heart Rhythm Society, and the Heart Rhythm Society. Heart Rhythm 9:4 (2012), 632–696 e21.
10. Wazni, O.M., Marrouche, N.F., Martin, D.O., Verma, A., Bhargava, M., Saliba, W., et al. Radiofrequency ablation vs antiarrhythmic drugs as first-line treatment of symptomatic atrial fibrillation: a randomized trial. JAMA 293:21 (2005), 2634–2640.
11. Wilber, D.J., Pappone, C., Neuzil, P., De Paola, A., Marchlinski, F., Natale, A., et al. Comparison of antiarrhythmic drug therapy and radiofrequency catheter ablation in patients with paroxysmal atrial fibrillation: a randomized controlled trial. JAMA 303:4 (2010), 333–340.
12. Pappone, C., Augello, G., Sala, S., Gugliotta, F., Vicedomini, G., Gulletta, S., et al. A randomized trial of circumferential pulmonary vein ablation versus antiarrhythmic drug therapy in paroxysmal atrial fibrillation: the APAF Study. Journal of the American College of Cardiology 48:11 (2006), 2340–2347.
13. Jais, P., Cauchemez, B., Macle, L., Daoud, E., Khairy, P., Subbiah, R., et al. Catheter ablation versus antiarrhythmic drugs for atrial fibrillation: the A4 study. Circulation 118:24 (2008), 2498–2505.
14. Weerasooriya, R., Khairy, P., Litalien, J., Macle, L., Hocini, M., Sacher, F., et al. Catheter ablation for atrial fibrillation: are results maintained at 5 years of follow-up?. Journal of the American College of Cardiology 57:2 (2011), 160–166.
15. Ouyang, F., Tilz, R., Chun, J., Schmidt, B., Wissner, E., Zerm, T., et al. Long-term results of catheter ablation in paroxysmal atrial fibrillation: lessons from a 5-year follow-up. Circulation 122:23 (2010), 2368–2377.
16. Steinberg, J.S., Palekar, R., Sichrovsky, T., Arshad, A., Preminger, M., Musat, D., et al. Very long-term outcome after initially successful catheter ablation of atrial fibrillation. Heart Rhythm 11:5 (2014), 771–776.
17. Ganesan, A.N., Shipp, N.J., Brooks, A.G., Kuklik, P., Lau, D.H., Lim, H.S., et al. Long-term outcomes of catheter ablation of atrial fibrillation: a systematic review and meta-analysis. Journal of the American Heart Association, 2(2), 2013, e004549.
18. Medi, C., Sparks, P.B., Morton, J.B., Kistler, P.M., Halloran, K., Rosso, R., et al. Pulmonary vein antral isolation for paroxysmal atrial fibrillation: results from long-term follow-up. Journal of Cardiovascular Electrophysiology 22:2 (2011), 137–141.
19. Shah, A.N., Mittal, S., Sichrovsky, T.C., Cotiga, D., Arshad, A., Maleki, K., et al. Long-term outcome following successful pulmonary vein isolation: pattern and prediction of very late recurrence. Journal of Cardiovascular Electrophysiology 19:7 (2008), 661–667.
20. Jongnarangsin, K., Chugh, A., Good, E., Mukerji, S., Dey, S., Crawford, T., et al. Body mass index, obstructive sleep apnea, and outcomes of catheter ablation of atrial fibrillation. Journal of Cardiovascular Electrophysiology 19:7 (2008), 668–672.
21. Mohanty, S., Mohanty, P., Di Biase, L., Bai, R., Pump, A., Santangeli, P., et al. Impact of metabolic syndrome on procedural outcomes in patients with atrial fibrillation undergoing catheter ablation. Journal of the American College of Cardiology 59:14 (2012), 1295–1301.
22. Abed, H.S., Wittert, G.A., Leong, D.P., Shirazi, M.G., Bahrami, B., Middeldorp, M.E., et al. Effect of weight reduction and cardiometabolic risk factor management on symptom burden and severity in patients with atrial fibrillation: a randomized clinical trial. JAMA 310:19 (2013), 2050–2060.
23. Pathak, R.K., Middeldorp, M.E., Lau, D.H., Mehta, A.B., Mahajan, R., Twomey, D., et al. Aggressive risk factor reduction study for atrial fibrillation and implications for the outcome of ablation: the ARREST-AF cohort study. Journal of the American College of Cardiology 64:21 (2014), 2222–2231.
24. Pathak, R.K., Middeldorp, M.E., Meredith, M., Mehta, A.B., Mahajan, R., Wong, C.X., et al. Long-Term Effect of Goal-Directed Weight Management in an Atrial Fibrillation Cohort: A Long-Term Follow-Up Study (LEGACY). Journal of the American College of Cardiology 65:20 (2015), 2159–2169.
25. Pathak, R.K., Elliott, A., Middeldorp, M.E., Meredith, M., Mehta, A.B., Mahajan, R., et al. Impact of CARDIOrespiratory FITness on Arrhythmia Recurrence in Obese Individuals With Atrial Fibrillation: The CARDIO-FIT Study. Journal of the American College of Cardiology 66:9 (2015), 985–996.
26. Hajhosseiny, R., Matthews, G.K., Lip, G.Y., Metabolic syndrome, atrial fibrillation, and stroke: Tackling an emerging epidemic. Heart Rhythm 12:11 (2015), 2332–2343.
27. Chamberlain, A.M., Agarwal, S.K., Ambrose, M., Folsom, A.R., Soliman, E.Z., Alonso, A., Metabolic syndrome and incidence of atrial fibrillation among blacks and whites in the Atherosclerosis Risk in Communities (ARIC) Study. American Heart Journal 159:5 (2010), 850–856.
28. Brundel, B.J., Henning, R.H., Kampinga, H.H., Van Gelder, I.C., Crijns, H.J., Molecular mechanisms of remodeling in human atrial fibrillation. Cardiovasc Res 54:2 (2002), 315–324.
29. Hobbs, W.J., Fynn, S., Todd, D.M., Wolfson, P., Galloway, M., Garratt, C.J., Reversal of atrial electrical remodeling after cardioversion of persistent atrial fibrillation in humans. Circulation 101:10 (2000), 1145–1151.
30. Ausma, J., Litjens, N., Lenders, M.H., Duimel, H., Mast, F., Wouters, L., et al. Time course of atrial fibrillation-induced cellular structural remodeling in atria of the goat. J Mol Cell Cardiol 33:12 (2001), 2083–2094.
31. Ausma, J., Wijffels, M., Thone, F., Wouters, L., Allessie, M., Borgers, M., Structural changes of atrial myocardium due to sustained atrial fibrillation in the goat. Circulation 96:9 (1997), 3157–3163.
32. Fynn, S.P., Todd, D.M., Hobbs, W.J., Armstrong, K.L., Fitzpatrick, A.P., Garratt, C.J., Clinical evaluation of a policy of early repeated internal cardioversion for recurrence of atrial fibrillation. Journal of Cardiovascular Electrophysiology 13:2 (2002), 135–141.
33. Stiles, M.K., John, B., Wong, C.X., Kuklik, P., Brooks, A.G., Lau, D.H., et al. Paroxysmal lone atrial fibrillation is associated with an abnormal atrial substrate: characterizing the second factor. Journal of the American College of Cardiology 53:14 (2009), 1182–1191.
34. Abed, H.S., Samuel, C.S., Lau, D.H., Kelly, D.J., Royce, S.G., Alasady, M., et al. Obesity results in progressive atrial structural and electrical remodeling: implications for atrial fibrillation. Heart Rhythm 10:1 (2013), 90–100.
35. Dimitri, H., Ng, M., Brooks, A.G., Kuklik, P., Stiles, M.K., Lau, D.H., et al. Atrial remodeling in obstructive sleep apnea: implications for atrial fibrillation. Heart Rhythm 9:3 (2012), 321–327.
36. Lau, D.H., Mackenzie, L., Kelly, D.J., Psaltis, P.J., Brooks, A.G., Worthington, M., et al. Hypertension and atrial fibrillation: evidence of progressive atrial remodeling with electrostructural correlate in a conscious chronically instrumented ovine model. Heart Rhythm 7:9 (2010), 1282–1290.
37. Casaclang-Verzosa, G., Gersh, B.J., Tsang, T.S., Structural and functional remodeling of the left atrium: clinical and therapeutic implications for atrial fibrillation. Journal of the American College of Cardiology 51:1 (2008), 1–11.
38. Wozakowska-Kaplon, B., Changes in left atrial size in patients with persistent atrial fibrillation: a prospective echocardiographic study with a 5-year follow-up period. Int J Cardiol 101:1 (2005), 47–52.
39. Kostin, S., Klein, G., Szalay, Z., Hein, S., Bauer, E.P., Schaper, J., Structural correlate of atrial fibrillation in human patients. Cardiovasc Res 54:2 (2002), 361–379.
40. Allessie, M., Ausma, J., Schotten, U., Electrical, contractile and structural remodeling during atrial fibrillation. Cardiovasc Res 54:2 (2002), 230–246.
41. Burstein, B., Nattel, S., Atrial fibrosis: mechanisms and clinical relevance in atrial fibrillation. Journal of the American College of Cardiology 51:8 (2008), 802–809.
42. Brundel, B.J., Van Gelder, I.C., Tuinenburg, A.E., Wietses, M., Van Veldhuisen, D.J., Van Gilst, W.H., et al. Endothelin system in human persistent and paroxysmal atrial fibrillation. Journal of Cardiovascular Electrophysiology 12:7 (2001), 737–742.
43. Mahajan, R., Lau, D.H., Sanders, P., Impact of obesity on cardiac metabolism, fibrosis, and function. Trends in Cardiovascular Medicine 25:2 (2015), 119–126.
44. Lau, D.H., Schotten, U., Mahajan, R., Antic, N.A., Hatem, S.N., Pathak, R.K., et al. Novel mechanisms in the pathogenesis of atrial fibrillation: practical applications. European Heart Journal 37:20 (2015), 1573–1581.
45. Shinagawa, K., Shi, Y.F., Tardif, J.C., Leung, T.K., Nattel, S., Dynamic nature of atrial fibrillation substrate during development and reversal of heart failure in dogs. Circulation 105:22 (2002), 2672–2678.
46. Guasch, E., Benito, B., Qi, X., Cifelli, C., Naud, P., Shi, Y., et al. Atrial fibrillation promotion by endurance exercise: demonstration and mechanistic exploration in an animal model. Journal of the American College of Cardiology 62:1 (2013), 68–77.
47. Kajaste, S., Brander, P.E., Telakivi, T., Partinen, M., Mustajoki, P., A cognitive-behavioral weight reduction program in the treatment of obstructive sleep apnea syndrome with or without initial nasal CPAP: a randomized study. Sleep Medicine 5:2 (2004), 125–131.
48. Tedrow, U.B., Conen, D., Ridker, P.M., Cook, N.R., Koplan, B.A., Manson, J.E., et al. The long- and short-term impact of elevated body mass index on the risk of new atrial fibrillation the WHS (women's health study). Journal of the American College of Cardiology 55:21 (2010), 2319–2327.
49. Huxley, R.R., Misialek, J.R., Agarwal, S.K., Loehr, L.R., Soliman, E.Z., Chen, L.Y., et al. Physical activity, obesity, weight change, and risk of atrial fibrillation: the Atherosclerosis Risk in Communities study. Circ Arrhythm Electrophysiol 7:4 (2014), 620–625.
50. Malmo, V., Nes, B.M., Amundsen, B.H., Tjonna, A.E., Stoylen, A., Rossvoll, O., et al. Aerobic Interval Training Reduces the Burden of Atrial Fibrillation in the Short Term: A Randomized Trial. Circulation 133:5 (2016), 466–473.
51. Patel, D., Mohanty, P., Di Biase, L., Shaheen, M., Lewis, W.R., Quan, K., et al. Safety and efficacy of pulmonary vein antral isolation in patients with obstructive sleep apnea: the impact of continuous positive airway pressure. Circ Arrhythm Electrophysiol 3:5 (2017), 445–451.
52. Fein, A.S., Shvilkin, A., Shah, D., Haffajee, C.I., Das, S., Kumar, K., et al. Treatment of obstructive sleep apnea reduces the risk of atrial fibrillation recurrence after catheter ablation. Journal of the American College of Cardiology 62:4 (2013), 300–305.
53. Caples, S.M., Somers, V.K., CPAP treatment for obstructive sleep apnoea in heart failure: expectations unmet. European Heart Journal 28:10 (2007), 1184–1186.
54. Naruse, Y., Tada, H., Satoh, M., Yanagihara, M., Tsuneoka, H., Hirata, Y., et al. Concomitant obstructive sleep apnea increases the recurrence of atrial fibrillation following radiofrequency catheter ablation of atrial fibrillation: clinical impact of continuous positive airway pressure therapy. Heart Rhythm 10:3 (2013), 331–337.
55. Kanagala, R., Murali, N.S., Friedman, P.A., Ammash, N.M., Gersh, B.J., Ballman, K.V., et al. Obstructive Sleep Apnea and the Recurrence of Atrial Fibrillation. Circulation 107:20 (2003), 2589–2594.
56. Hohl, M., Linz, B., Böhm, M., Linz, D., Obstructive Sleep Apnea and Atrial Arrhythmogenesis. Current Cardiology Reviews 10:4 (2014), 362–368.
57. Sharma, S.K., Agrawal, S., Damodaran, D., Sreenivas, V., Kadhiravan, T., Lakshmy, R., et al. CPAP for the metabolic syndrome in patients with obstructive sleep apnea. The New England Journal of Medicine 365:24 (2011), 2277–2286.
58. Badheka, A.O., Patel, N.J., Grover, P.M., Shah, N., Patel, N., Singh, V., et al. Optimal blood pressure in patients with atrial fibrillation (from the AFFIRM Trial). The American Journal of Cardiology 114:5 (2014), 727–736.
59. Santoro, F., Di Biase, L., Trivedi, C., Burkhardt, J.D., Paoletti Perini, A., Sanchez, J., et al. Impact of Uncontrolled Hypertension on Atrial Fibrillation Ablation Outcome. Journal of the American College of Cardiology: Clinical Electrophysiology 1:3 (2015), 164–173.
60. Perez, M.V., Wang, P.J., Larson, J.C., Soliman, E.Z., Limacher, M., Rodriguez, B., et al. Risk factors for atrial fibrillation and their population burden in postmenopausal women: the Women's Health Initiative Observational Study. Heart 99:16 (2013), 1173–1178.
61. Parkash, R., Wells, G.A., Sapp, J., Healey, J.S., Tardif, J.C., Greiss, I., et al. Atrial substrate modification with aggressive blood pressure control to prevent atrial fibrillation (SMAC AF). Circulation 135:19 (2017), 1788–1798.
62. Lau, D.H., Hendriks, J.M.L., Kalman, J.M., Sanders, P., Blood pressure control in atrial fibrillation: one of many critical components in risk factor modification. Circulation 135:19 (2017), 1799–1801.
63. Fatemi, O., Yuriditsky, E., Tsioufis, C., Tsachris, D., Morgan, T., Basile, J., et al. Impact of Intensive Glycemic Control on the Incidence of Atrial Fibrillation and Associated Cardiovascular Outcomes in Patients with Type 2 Diabetes Mellitus (from the ACCORD Study). The American Journal of Cardiology 114:8 (2014), 1217–1222.
64. Chang, S.-H., Wu, L.-S., Chiou, M.-J., Liu, J.-R., Yu, K.-H., Kuo, C.-F., et al. Association of metformin with lower atrial fibrillation risk among patients with type 2 diabetes mellitus: a population-based dynamic cohort and in vitro studies. Cardiovascular Diabetology, 13(1), 2014, 123.
65. Alonso, A., Yin, X., Roetker, N.S., Magnani, J.W., Kronmal, R.A., Ellinor, P.T., et al. Blood lipids and the incidence of atrial fibrillation: the Multi-Ethnic Study of Atherosclerosis and the Framingham Heart Study. Journal of the American Heart Association, 3(5), 2014, e001211.
66. Mora, S., Akinkuolie, A.O., Sandhu, R.K., Conen, D., Albert, C.M., Paradoxical association of lipoprotein measures with incident atrial fibrillation. Circ Arrhythm Electrophysiol 7:4 (2014), 612–619.
67. Watanabe, H., Tanabe, N., Yagihara, N., Watanabe, T., Aizawa, Y., Kodama, M., Association between lipid profile and risk of atrial fibrillation. Circulation Journal 75:12 (2011), 2767–2774.
68. Fang, W.-T., Li, H.-J., Zhang, H., Jiang, S., The role of statin therapy in the prevention of atrial fibrillation: a meta-analysis of randomized controlled trials. British Journal of Clinical Pharmacology 74:5 (2012), 744–756.
69. Fauchier, L., Clementy, N., Babuty, D., Statin therapy and atrial fibrillation: systematic review and updated meta-analysis of published randomized controlled trials. Current Opinion in Cardiology 28:1 (2013), 7–18.
70. Sicouri, S., Gianetti, B., Zygmunt, A.C., Cordeiro, J.M., Antzelevitch, C., Antiarrhythmic Effects of Simvastatin in Canine Pulmonary Vein Sleeve Preparations. Journal of the American College of Cardiology 57:8 (2011), 986–993.
71. Shiroshita-Takeshita, A., Schram, G., Lavoie, J., Nattel, S., Effect of simvastatin and antioxidant vitamins on atrial fibrillation promotion by atrial-tachycardia remodeling in dogs. Circulation 110:16 (2004), 2313–2319.
72. Pathak, R.K., Evans, M., Middeldorp, M.E., Mahajan, R., Mehta, A.B., Meredith, M., et al. Cost-effectiveness and clinical effectiveness of the risk factor management clinic in atrial fibrillation: the CENT study. Journal of the American College of Cardiology: Clinical Electrophysiology 3:5 (2017), 436–447.
73. Kirchhof, P., Benussi, S., Kotecha, D., Ahlsson, A., Atar, D., Casadei, B., et al. ESC Guidelines for the management of atrial fibrillation developed in collaboration with EACTS. European Journal of Cardio-Thoracic Surgery: official journal of the European Association for Cardio-Thoracic Surgery 50:5 (2016), e1–e88.
74. Hendriks, J.M., de Wit, R., Crijns, H.J., Vrijhoef, H.J., Prins, M.H., Pisters, R., et al. Nurse-led care vs. usual care for patients with atrial fibrillation: results of a randomized trial of integrated chronic care vs. routine clinical care in ambulatory patients with atrial fibrillation. European Heart Journal 33:21 (2012), 2692–2699.