Obstructive sleep apnea and atrial arrhythmogenesis

Current Cardiology Reviews

Volumn 10, Issue 4, 2014, Pages 362-368

  Hohl, Mathias ^a   Linz, Benedikt ^a   Böhm, Michael ^a   Linz, Dominik ^a  

^a SAARLAND UNIVERSITY   (Germany)

Author keywords

Animal experiment; Atrial electrophysiology; Atrial fibrillation; Continuous positive airway pressure; Obstructive sleep apnea; Renal denervation

Indexed keywords

ARRHYTHMOGENESIS; BLOOD GAS; CHRONIC OBSTRUCTIVE LUNG DISEASE; ELECTROPHYSIOLOGY; HEART ATRIUM; HEART ATRIUM FIBRILLATION; HUMAN; HYPERTENSION; INFLAMMATION; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REVIEW; SLEEP DISORDERED BREATHING; THORAX PRESSURE;

ANIMALS; ATRIAL FIBRILLATION; BLOOD PRESSURE; DISEASE PROGRESSION; ELECTROPHYSIOLOGICAL PROCESSES; HEART ATRIA; HEMODYNAMICS; HUMANS; OBESITY; PREVALENCE; SLEEP APNEA, OBSTRUCTIVE;

EID: 84904732692     PISSN: 1573403X     EISSN: 18756557     Source Type: Journal    
DOI: 10.2174/1573403X1004140707125137     Document Type: Review

References (49)

1. Kirchhof P, Bax J, Blomstrom-Lundquist C, et al. Early and comprehensive management of atrial fibrillation: executive summary of the proceedings from the 2nd AFNET-EHRA consensus conference "research perspectives in AF". Eur Heart J 2009; 30: 2969-77.
2. Schoonderwoerd BA, Smit MD, Pen L, Van Gelder IC. New risk factors for atrial fibrillation: causes of 'not-so-lone atrial fibrillation'. Europace 2008; 10: 668-73.
3. Johnson KG, Johnson DC. Obstructive sleep apnea is a risk factor for stroke and atrial fibrillation. Chest 2010; 138: 239.
4. Kanagala R, Murali NS, Friedman PA, et al. Obstructive sleep apnea and the recurrence of atrial fibrillation. Circulation 2003; 107: 2589-94.
5. Gami AS, Hodge DO, Herges RM, et al. Obstructive sleep apnea, obesity, and the risk of incident atrial fibrillation. J Am Coll Cardiol 2007; 49: 565-71.
6. Stevenson IH, Teichtahl H, Cunnington D, Ciavarella S, Gordon I, Kalman JM. Prevalence of sleep disordered breathing in paroxysmal and persistent atrial fibrillation patients with normal left ventricular function. Eur Heart J 2008; 29: 1662-9.
7. Albuquerque FN, Calvin AD, Sert Kuniyoshi FH, et al. Sleepdisordered breathing and excessive daytime sleepiness in patients with atrial fibrillation. Chest 2012; 141: 967-73.
8. Patel D, Mohanty P, Di Biase L, et al. Safety and efficacy of pulmonary vein antral isolation in patients with obstructive sleep apnea: the impact of continuous positive airway pressure. Circ Arrhythm Electrophysiol2010; 3: 445-51.
9. Monahan K, Brewster J, Wang L, et al. Relation of the severity of obstructive sleep apnea in response to anti-arrhythmic drugs in patients with atrial fibrillation or atrial flutter. Am J Cardiol 2012; 110: 369-72.
10. Kasai T, Bradley TD. Obstructive sleep apnea and heart failure: pathophysiologic and therapeutic implications. J Am Coll Cardiol 2011; 57: 119-27.
11. Parish JM, Somers VK. Obstructive sleep apnea and cardiovascular disease. Mayo Clin Proc 2004; 79: 1036-46.
12. Monahan K, Storfer-Isser A, Mehra R, et al. Triggering of nocturnal arrhythmias by sleep-disordered breathing events. J Am Coll Cardiol 2009; 54: 1797-804.
13. Kohler M, Stradling JR. Mechanisms of vascular damage in obstructive sleep apnea. Nat Rev Cardiol 2010; 7: 677-85.
14. Linz D, Schotten U, Neuberger HR, Böhm M, Wirth K. Negative tracheal pressure during obstructive respiratory events promotes atrial fibrillation by vagal activation. Heart Rhythm 2011; 8: 1436-43.
15. Orban M, Bruce CJ, Pressman GS, et al. Dynamic changes of left ventricular performance and left atrial volume induced by the mueller maneuver in healthy young adults and implications for obstructive sleep apnea, atrial fibrillation, and heart failure. Am J Cardiol 2008; 102: 1557-61.
16. Ravelli F, Allessie M. Effects of atrial dilatation on refractory period and vulnerability to atrial fibrillation in the isolated Langendorff-perfused rabbit heart. Circulation 1997; 96(5): 1686-95.
17. Eijsbouts SC, Majidi M, van Zandvoort M, Allessie MA. Effects of acute atrial dilation on heterogeneity in conduction in the isolated rabbit heart. J Cardiovasc Electrophysiol 2003; 14(3): 269-78.
18. Schotten U, Verheule S, Kirchhof P, Goette A. Pathophysiological mechanisms of atrial fibrillation: a translational appraisal. Physiol Rev 2011; 91: 265-325.
19. Linz D, Mahfoud F, Schotten U, et al. Renal sympathetic denervation suppresses postapneic blood pressure rises and atrial fibrillation in a model for sleep apnea. Hypertension 2012; 60: 172-8.
20. Linz D, Schotten U, Neuberger HR, Böhm M, Wirth K. Combined blockade of early and late activated atrial potassium currents suppresses atrial fibrillation in a pig model of obstructive apnea. Heart Rhythm 2011; 8: 1933-9.
21. Linz D, Hohl M, Nickel A, et al. Effect of renal denervation on neurohumoral activation triggering atrial fibrillation in obstructive sleep apnea. Hypertension 2013; 62: 767-74.
22. Iwasaki YK, Shi Y, Benito B, et al. Determinants of atrial fibrillation in an animal model of obesity and acute obstructive sleep apnea. Heart Rhythm 2012; 9: 1409-16.
23. Stevenson IH, Roberts-Thomson KC, Kistler PM, et al. Atrial electrophysiology is altered by acute hypercapnia but not hypoxemia: implications for promotion of atrial fibrillation in pulmonary disease and sleep apnea. Heart Rhythm 2010; 7: 1263-70.
24. Lammers WJ, Kirchhof C, Bonke FI, Allessie MA. Vulnerability of rabbit atrium to reentry by hypoxia. Role of inhomogeneity in conduction and wavelength. Am J Physiol 1992; 262: H47-55.
25. Lin YK, Lai MS, Chen YC, et al. Hypoxia and reoxygenation modulate the arrhythmogenic activity of the pulmonary vein and atrium. Clin Sci (Lond) 2012; 122: 121-32.
26. Heusser K, Dzamonja G, Breskovic T, et al. Sympathetic and cardiovascular responses to glossopharyngeal insufflation in trained apnea divers. J Appl Physiol 2010; 109: 1728-35.
27. Linz D, Ukena C, Mahfoud F, Neuberger HR, Böhm M. Atrial autonomic innervation: a target for interventional antiarrhythmic therapy? J Am Coll Cardiol 2014; 63: 215-24.
28. Linz D, van Hunnik A, Ukena C, et al. Renal denervation: effects on atrial electrophysiology and arrhythmias. Clin Res Cardiol 2014 Mar 29. [Epub ahead of print].
29. Ghias M, Scherlag BJ, Lu Z, et al. The role of ganglionated plexi in apnea-related atrial fibrillation. J Am Coll Cardiol 2009; 54: 2075-83.
30. Hering D, Lambert EA, Marusic P, et al. Substantial reduction in single sympathetic nerve firing after renal denervation in patients with resistant hypertension. Hypertension. 2013; 61: 457-64.
31. Witkowski A, Prejbisz A, Florczak E, et al. Effects of renal sympathetic denervation on blood pressure, sleep apnea course, and glycemic control in patients with resistant hypertension and sleep apnea. Hypertension 2011; 58: 559-65.
32. Dimitri H, Ng M, Brooks AG, et al. Atrial remodeling in obstructive sleep apnea: Implications for atrial fibrillation. Heart Rhythm 2011; 9: 321-7.
33. Yagmur J, Yetkin O, Cansel M, et al. Assessment of atrial electromechanical delay and influential factors in patients with obstructive sleep apnea. Sleep Breath 2012; 16: 83-8.
34. Ohga E, Tomita T, Wada H, Yamamoto H, Nagase T, Ouchi Y. Effects of obstructive sleep apnea on circulating ICAM-1, IL-8, and MCP-1. J Appl Physiol 2003; 94: 179-84.
35. Shamsuzzaman AS, Winnicki M, Lanfranchi P, et al. Elevated Creactive protein in patients with obstructive sleep apnea. Circulation 2002; 105: 2462-4.
36. Møller DS, Lind P, Strunge B, Pedersen EB. Abnormal vasoactive hormones and 24-hour blood pressure in obstructive sleep apnea. Am J Hypertens 2003; 16: 274-80.
37. Mancuso M, Bonanni E, LoGerfo A, et al. Oxidative stress biomarkers in patients with untreated obstructive sleep apnea syndrome. Sleep Med 2012; 13: 632-6.
38. Linz D, Mahfoud F, Linz B, et al. Effect of Obstructive Respiratory Events on Blood Pressure and Renal Perfusion in a Pig Model for Sleep Apnea. Am J Hypertens 2014 Mar 12. [Epub ahead of print].
39. Peppard PE, Young T, Palta M, Skatrud J. Prospective study of the association between sleep-disordered breathing and hypertension. N Engl J Med 2000; 342: 1378-84.
40. Logan AG, Perlikowski SM, Mente A, et al. High prevalence of unrecognized sleep apnoea in drug-resistant hypertension. J Hypertens 2001; 19: 2271-7.
41. Kistler PM, Sanders P, Dodic M, et al. Atrial electrical and structural abnormalities in an ovine model of chronic blood pressure elevation after prenatal corticosteroid exposure: implications for development of atrial fibrillation. Eur Heart J 2006; 27: 3045-56.
42. Lau DH, Mackenzie L, Kelly DJ, et al. Hypertension and atrial fibrillation: evidence of progressive atrial remodeling with electrostructural correlate in a conscious chronically instrumented ovine model. Heart Rhythm 2010; 7: 1282-90.
43. Choisy SC, Arberry LA, Hancox JC, James AF. Increased susceptibility to atrial tachyarrhythmia in spontaneously hypertensive rat hearts. Hypertension 2007; 49: 498-505.
44. Neuberger HR, Schotten U, Blaauw Y, et al. Chronic atrial dilation, electrical remodeling, and atrial fibrillation in the goat. J Am Coll Cardiol 2006; 47: 644-53.
45. Dublin S, French B, Glazer NL, et al. Risk of new-onset atrial fibrillation in relation to body mass index. Arch Intern Med 2006; 166: 2322-8.
46. Wong CX, Abed HS, Molaee P, et al. Pericardial fat is associated with atrial fibrillation severity and ablation outcome. J Am Coll Cardiol 2011; 57: 1745-51.
47. Abed HS, Samuel CS, Lau DH, et al. Obesity results in progressive atrial structural and electrical remodeling: Implications for atrial fibrillation. Heart Rhythm 2013; 10: 90-100.
48. Linz D, Ukena C, Neuberger HR. Treatment of obstructive sleep apnoea improves metabolic conditions and prevents initiation of antiarrhythmic therapy in a patient with atrial fibrillation. Europace 2014; 16: 245.
49. Li L, Wang ZW, Li J, et al. Efficacy of catheter ablation of atrial fibrillation in patients with obstructive sleep apnoea with and without continuous positive airway pressure treatment: a meta-analysis of observational studies. Europace 2014 Apr 2. [Epub ahead of print].