-
1
-
-
84918815964
-
Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012
-
Ferlay J, Soerjomataram I, Dikshit R, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer 2015;136:E359-86
-
(2015)
Int J Cancer
, vol.136
, pp. E359-E386
-
-
Ferlay, J.1
Soerjomataram, I.2
Dikshit, R.3
-
3
-
-
0022647432
-
The product of the human c-erbB-2 gene: a 185-kilodalton glycoprotein with tyrosine kinase activity
-
Akiyama T, Sudo C, Ogawara H, et al. The product of the human c-erbB-2 gene: a 185-kilodalton glycoprotein with tyrosine kinase activity. Science 1986;232:1644-6
-
(1986)
Science
, vol.232
, pp. 1644-1646
-
-
Akiyama, T.1
Sudo, C.2
Ogawara, H.3
-
4
-
-
0034600849
-
The ErbB signaling network: receptor heterodimerization in development and cancer
-
Olayioye MA, Neve RM, Lane HA, et al. The ErbB signaling network: receptor heterodimerization in development and cancer. EMBO J 2000;19:3159-67
-
(2000)
EMBO J
, vol.19
, pp. 3159-3167
-
-
Olayioye, M.A.1
Neve, R.M.2
Lane, H.A.3
-
5
-
-
79961024637
-
Targeting the human EGFR family in esophagogastric cancer
-
Okines A, Cunningham D, Chau I. Targeting the human EGFR family in esophagogastric cancer. Nat Rev Clin Oncol 2011;8:492-503
-
(2011)
Nat Rev Clin Oncol
, vol.8
, pp. 492-503
-
-
Okines, A.1
Cunningham, D.2
Chau, I.3
-
6
-
-
84929684125
-
Recent advances in the HER2 targeted therapy of gastric cancer
-
Matsuoka T, Yashiro M. Recent advances in the HER2 targeted therapy of gastric cancer. World J Clin Cases 2015;3:42-51
-
(2015)
World J Clin Cases
, vol.3
, pp. 42-51
-
-
Matsuoka, T.1
Yashiro, M.2
-
7
-
-
0034869825
-
The basic biology of HER2
-
Rubin I, Yarden Y. The basic biology of HER2. Ann Oncol 2001;12 Suppl 1:S3-8
-
(2001)
Ann Oncol
, vol.12
, pp. S3-S8
-
-
Rubin, I.1
Yarden, Y.2
-
8
-
-
77956262693
-
Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial
-
Bang YJ, Van Cutsem E, Feyereislova A, et al. Trastuzumab in combination with chemotherapy versus chemotherapy alone for treatment of HER2-positive advanced gastric or gastro-oesophageal junction cancer (ToGA): a phase 3, open-label, randomised controlled trial. Lancet 2010;376:687-97
-
(2010)
Lancet
, vol.376
, pp. 687-697
-
-
Bang, Y.J.1
Van Cutsem, E.2
Feyereislova, A.3
-
9
-
-
50849123421
-
HER2 in gastric cancer: a new prognostic factor and a novel therapeutic target
-
Gravalos C, Jimeno A. HER2 in gastric cancer: a new prognostic factor and a novel therapeutic target. Ann Oncol 2008;19:1523-9
-
(2008)
Ann Oncol
, vol.19
, pp. 1523-1529
-
-
Gravalos, C.1
Jimeno, A.2
-
11
-
-
84941959187
-
Optimal Patient Selection for Trastuzumab Treatment in HER2-Positive Advanced Gastric Cancer
-
Ock CY, Lee KW, Kim JW, et al. Optimal Patient Selection for Trastuzumab Treatment in HER2-Positive Advanced Gastric Cancer. Clin Cancer Res 2015;21:2520-9
-
(2015)
Clin Cancer Res
, vol.21
, pp. 2520-2529
-
-
Ock, C.Y.1
Lee, K.W.2
Kim, J.W.3
-
12
-
-
80051647503
-
Prognostic implications of altered human epidermal growth factor receptors (HERs) in gastric carcinomas: HER2 and HER3 are predictors of poor outcome
-
Begnami MD, Fukuda E, Fregnani JH, et al. Prognostic implications of altered human epidermal growth factor receptors (HERs) in gastric carcinomas: HER2 and HER3 are predictors of poor outcome. J Clin Oncol 2011;29:3030-6
-
(2011)
J Clin Oncol
, vol.29
, pp. 3030-3036
-
-
Begnami, M.D.1
Fukuda, E.2
Fregnani, J.H.3
-
13
-
-
80052697178
-
Evaluation of HER2 protein expression in gastric carcinomas: comparative analysis of 1, 414 cases of whole-tissue sections and 595 cases of tissue microarrays
-
Kim KC, Koh YW, Chang HM, et al. Evaluation of HER2 protein expression in gastric carcinomas: comparative analysis of 1, 414 cases of whole-tissue sections and 595 cases of tissue microarrays. Ann Surg Oncol 2011;18:2833-40
-
(2011)
Ann Surg Oncol
, vol.18
, pp. 2833-2840
-
-
Kim, K.C.1
Koh, Y.W.2
Chang, H.M.3
-
14
-
-
0033135820
-
The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas
-
Nakajima M, Sawada H, Yamada Y, et al. The prognostic significance of amplification and overexpression of c-met and c-erb B-2 in human gastric carcinomas. Cancer 1999;85:1894-902
-
(1999)
Cancer
, vol.85
, pp. 1894-1902
-
-
Nakajima, M.1
Sawada, H.2
Yamada, Y.3
-
15
-
-
33748154637
-
HER-2/neu amplification is an independent prognostic factor in gastric cancer
-
Park DI, Yun JW, Park JH, et al. HER-2/neu amplification is an independent prognostic factor in gastric cancer. Dig Dis Sci 2006;51:1371-9
-
(2006)
Dig Dis Sci
, vol.51
, pp. 1371-1379
-
-
Park, D.I.1
Yun, J.W.2
Park, J.H.3
-
16
-
-
84864551756
-
HER2/neu testing for anti-HER2-based therapies in patients with unresectable and/or metastatic gastric cancer
-
Gómez-Martin C, Garralda E, Echarri MJ, et al. HER2/neu testing for anti-HER2-based therapies in patients with unresectable and/or metastatic gastric cancer. J Clin Pathol 2012;65:751-7
-
(2012)
J Clin Pathol
, vol.65
, pp. 751-757
-
-
Gómez-Martin, C.1
Garralda, E.2
Echarri, M.J.3
-
17
-
-
84867131579
-
Prognosis of metastatic gastric and gastroesophageal junction cancer by HER2 status: a European and USA International collaborative analysis
-
Janjigian YY, Werner D, Pauligk C, et al. Prognosis of metastatic gastric and gastroesophageal junction cancer by HER2 status: a European and USA International collaborative analysis. Ann Oncol 2012;23:2656-62
-
(2012)
Ann Oncol
, vol.23
, pp. 2656-2662
-
-
Janjigian, Y.Y.1
Werner, D.2
Pauligk, C.3
-
18
-
-
84964002490
-
-
[02.17.2016]
-
NCCN. NCCN Guidelines Version 3. 2015 Gastric Cancer. 2015 [02.17.2016]. Available online: https://www.nccn.org/professionals/physician_gls/f_guidelines.asp
-
(2015)
NCCN Guidelines Version 3. 2015 Gastric Cancer
-
-
-
19
-
-
44249092320
-
Assessment of a HER2 scoring system for gastric cancer: results from a validation study
-
Hofmann M, Stoss O, Shi D, et al. Assessment of a HER2 scoring system for gastric cancer: results from a validation study. Histopathology 2008;52:797-805
-
(2008)
Histopathology
, vol.52
, pp. 797-805
-
-
Hofmann, M.1
Stoss, O.2
Shi, D.3
-
20
-
-
84872874041
-
A novel proteomics-based clinical diagnostics technology identifies heterogeneity in activated signaling pathways in gastric cancers
-
Lee J, Kim S, Kim P, et al. A novel proteomics-based clinical diagnostics technology identifies heterogeneity in activated signaling pathways in gastric cancers. PLoS One 2013;8:e54644
-
(2013)
PLoS One
, vol.8
-
-
Lee, J.1
Kim, S.2
Kim, P.3
-
21
-
-
84894363816
-
Level of HER2 gene amplification predicts response and overall survival in HER2-positive advanced gastric cancer treated with trastuzumab
-
Gomez-Martin C, Plaza JC, Pazo-Cid R, et al. Level of HER2 gene amplification predicts response and overall survival in HER2-positive advanced gastric cancer treated with trastuzumab. J Clin Oncol 2013;31:4445-52
-
(2013)
J Clin Oncol
, vol.31
, pp. 4445-4452
-
-
Gomez-Martin, C.1
Plaza, J.C.2
Pazo-Cid, R.3
-
22
-
-
79955468866
-
Comparison of HER2 status in primary and paired metastatic sites of gastric carcinoma
-
Bozzetti C, Negri FV, Lagrasta CA, et al. Comparison of HER2 status in primary and paired metastatic sites of gastric carcinoma. Br J Cancer 2011;104:1372-6
-
(2011)
Br J Cancer
, vol.104
, pp. 1372-1376
-
-
Bozzetti, C.1
Negri, F.V.2
Lagrasta, C.A.3
-
23
-
-
0025318271
-
Characterization of murine monoclonal antibodies reactive to either the human epidermal growth factor receptor or HER2/neu gene product
-
Fendly BM, Winget M, Hudziak RM, et al. Characterization of murine monoclonal antibodies reactive to either the human epidermal growth factor receptor or HER2/neu gene product. Cancer Res 1990;50:1550-8
-
(1990)
Cancer Res
, vol.50
, pp. 1550-1558
-
-
Fendly, B.M.1
Winget, M.2
Hudziak, R.M.3
-
24
-
-
84860893882
-
-
[2016]
-
FDA. Full Prescribing Information for Trastuzumab. 2010 [2016]; Available online: http://www.accessdata.fda.gov/drugsatfda_docs/label/2010/103792s5250lbl.pdf
-
(2010)
Full Prescribing Information for Trastuzumab
-
-
-
25
-
-
84941960823
-
-
[cited 2016]
-
EMA. Summary of Positive Opinion for Herceptin. 2009 [cited 2016]; Available online: http://www.ema.europa.eu/docs/en_GB/document_library/Summary_of_opinion/human/000278/WC500059913.pdf
-
(2009)
Summary of Positive Opinion for Herceptin
-
-
-
26
-
-
84958162992
-
Optimal regimen of trastuzumab in combination with oxaliplatin/capecitabine in first-line treatment of HER2-positive advanced gastric cancer (CGOG1001): a multicenter, phase II trial
-
Gong J, Liu T, Fan Q, et al. Optimal regimen of trastuzumab in combination with oxaliplatin/capecitabine in first-line treatment of HER2-positive advanced gastric cancer (CGOG1001): a multicenter, phase II trial. BMC Cancer 2016;16:68
-
(2016)
BMC Cancer
, vol.16
, pp. 68
-
-
Gong, J.1
Liu, T.2
Fan, Q.3
-
27
-
-
84983536857
-
Phase II study of trastuzumab in combination with capecitabine and oxaliplatin in patients with advanced gastric cancer
-
Ryu MH, Ryoo BY, Park YS, et al. Phase II study of trastuzumab in combination with capecitabine and oxaliplatin in patients with advanced gastric cancer. J Clin Onco 2014;32:abstr 83
-
(2014)
J Clin Onco
, vol.32
-
-
Ryu, M.H.1
Ryoo, B.Y.2
Park, Y.S.3
-
28
-
-
20544460650
-
Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancer
-
Buzdar AU, Ibrahim NK, Francis D, et al. Significantly higher pathologic complete remission rate after neoadjuvant therapy with trastuzumab, paclitaxel, and epirubicin chemotherapy: results of a randomized trial in human epidermal growth factor receptor 2-positive operable breast cancer. J Clin Oncol 2005;23:3676-85
-
(2005)
J Clin Oncol
, vol.23
, pp. 3676-3685
-
-
Buzdar, A.U.1
Ibrahim, N.K.2
Francis, D.3
-
29
-
-
80052728749
-
Four-year follow-up of trastuzumab plus adjuvant chemotherapy for operable human epidermal growth factor receptor 2-positive breast cancer: joint analysis of data from NCCTG N9831 and NSABP B-31
-
Perez EA, Romond EH, Suman VJ Jr, et al. Four-year follow-up of trastuzumab plus adjuvant chemotherapy for operable human epidermal growth factor receptor 2-positive breast cancer: joint analysis of data from NCCTG N9831 and NSABP B-31. J Clin Oncol 2011;29:3366-73
-
(2011)
J Clin Oncol
, vol.29
, pp. 3366-3373
-
-
Perez, E.A.1
Romond, E.H.2
Suman, V.J.3
-
30
-
-
80053539103
-
Adjuvant trastuzumab in HER2-positive breast cancer
-
Slamon D, Eiermann W, Robert N, et al. Adjuvant trastuzumab in HER2-positive breast cancer. N Engl J Med 2011;365:1273-83
-
(2011)
N Engl J Med
, vol.365
, pp. 1273-1283
-
-
Slamon, D.1
Eiermann, W.2
Robert, N.3
-
31
-
-
84892141177
-
NeoHx study: Perioperative treatment with trastuzumab in combination with capecitabine and oxaliplatin (XELOX-T) in patients with HER2 resectable stomach or esophagogastric junction (EGJ) adenocarcinoma-R0 resection, pCR, and toxicity analysis
-
Rivera F, Jimenez P, Garcia Alfonso P, et al. NeoHx study: Perioperative treatment with trastuzumab in combination with capecitabine and oxaliplatin (XELOX-T) in patients with HER2 resectable stomach or esophagogastric junction (EGJ) adenocarcinoma-R0 resection, pCR, and toxicity analysis. J Clin Oncol 2013;31:abstr 4098
-
(2013)
J Clin Oncol
, vol.31
-
-
Rivera, F.1
Jimenez, P.2
Garcia Alfonso, P.3
-
32
-
-
77649162889
-
Lapatinib, a dual EGFR and HER2 kinase inhibitor, selectively inhibits HER2-amplified human gastric cancer cells and is synergistic with trastuzumab in vitro and in vivo
-
Wainberg ZA, Anghel A, Desai AJ, et al. Lapatinib, a dual EGFR and HER2 kinase inhibitor, selectively inhibits HER2-amplified human gastric cancer cells and is synergistic with trastuzumab in vitro and in vivo. Clin Cancer Res 2010;16:1509-19
-
(2010)
Clin Cancer Res
, vol.16
, pp. 1509-1519
-
-
Wainberg, Z.A.1
Anghel, A.2
Desai, A.J.3
-
33
-
-
80054057131
-
Southwest Oncology Group study S0413: a phase II trial of lapatinib (GW572016) as first-line therapy in patients with advanced or metastatic gastric cancer
-
Iqbal S, Goldman B, Fenoglio-Preiser CM, et al. Southwest Oncology Group study S0413: a phase II trial of lapatinib (GW572016) as first-line therapy in patients with advanced or metastatic gastric cancer. Ann Oncol 2011;22:2610-5
-
(2011)
Ann Oncol
, vol.22
, pp. 2610-2615
-
-
Iqbal, S.1
Goldman, B.2
Fenoglio-Preiser, C.M.3
-
34
-
-
84905566147
-
Lapatinib plus paclitaxel versus paclitaxel alone in the second-line treatment of HER2-amplified advanced gastric cancer in Asian populations: TyTAN-a randomized, phase III study
-
Satoh T, Xu RH, Chung HC, et al. Lapatinib plus paclitaxel versus paclitaxel alone in the second-line treatment of HER2-amplified advanced gastric cancer in Asian populations: TyTAN-a randomized, phase III study. J Clin Oncol 2014;32:2039-49
-
(2014)
J Clin Oncol
, vol.32
, pp. 2039-2049
-
-
Satoh, T.1
Xu, R.H.2
Chung, H.C.3
-
35
-
-
84958818670
-
Lapatinib in Combination With Capecitabine Plus Oxaliplatin in Human Epidermal Growth Factor Receptor 2-Positive Advanced or Metastatic Gastric, Esophageal, or Gastroesophageal Adenocarcinoma: TRIO-013/LOGiC-A Randomized Phase III Trial
-
Hecht JR, Bang YJ, Qin SK, et al. Lapatinib in Combination With Capecitabine Plus Oxaliplatin in Human Epidermal Growth Factor Receptor 2-Positive Advanced or Metastatic Gastric, Esophageal, or Gastroesophageal Adenocarcinoma: TRIO-013/LOGiC-A Randomized Phase III Trial. J Clin Oncol 2016;34:443-51
-
(2016)
J Clin Oncol
, vol.34
, pp. 443-451
-
-
Hecht, J.R.1
Bang, Y.J.2
Qin, S.K.3
-
36
-
-
0029814271
-
A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor
-
Tzahar E, Waterman H, Chen X, et al. A hierarchical network of interreceptor interactions determines signal transduction by Neu differentiation factor/neuregulin and epidermal growth factor. Mol Cell Biol 1996;16:5276-87
-
(1996)
Mol Cell Biol
, vol.16
, pp. 5276-5287
-
-
Tzahar, E.1
Waterman, H.2
Chen, X.3
-
37
-
-
79960972076
-
Pertuzumab in combination with trastuzumab shows significantly enhanced antitumor activity in HER2-positive human gastric cancer xenograft models
-
Yamashita-Kashima Y, Iijima S, Yorozu K, et al. Pertuzumab in combination with trastuzumab shows significantly enhanced antitumor activity in HER2-positive human gastric cancer xenograft models. Clin Cancer Res 2011;17:5060-70
-
(2011)
Clin Cancer Res
, vol.17
, pp. 5060-5070
-
-
Yamashita-Kashima, Y.1
Iijima, S.2
Yorozu, K.3
-
38
-
-
84901639476
-
Trastuzumab emtansine versus treatment of physician's choice for pretreated HER2-positive advanced breast cancer (TH3RESA): a randomised, open-label, phase 3 trial
-
Krop IE, Kim SB, Gonzalez-Martin A, et al. Trastuzumab emtansine versus treatment of physician's choice for pretreated HER2-positive advanced breast cancer (TH3RESA): a randomised, open-label, phase 3 trial. Lancet Oncol 2014;15:689-99
-
(2014)
Lancet Oncol
, vol.15
, pp. 689-699
-
-
Krop, I.E.1
Kim, S.B.2
Gonzalez-Martin, A.3
-
39
-
-
79955475247
-
Trastuzumab-DM1 is highly effective in preclinical models of HER2-positive gastric cancer
-
Barok M, Tanner M, Koninki K, et al. Trastuzumab-DM1 is highly effective in preclinical models of HER2-positive gastric cancer. Cancer Lett 2011;306:171-9
-
(2011)
Cancer Lett
, vol.306
, pp. 171-179
-
-
Barok, M.1
Tanner, M.2
Koninki, K.3
-
40
-
-
85002252067
-
A randomized, open-label, multicenter, adaptive phase 2/3 study of trastuzumab emtansine (T-DM1) versus a taxane (TAX) in patients (pts) with previously treated HER2-positive locally advanced or metastatic gastric/gastroesophageal junction adenocarcinoma (LA/MGC/GEJC)
-
Kang YK, Shah MA, Ohtsu A, et al. A randomized, open-label, multicenter, adaptive phase 2/3 study of trastuzumab emtansine (T-DM1) versus a taxane (TAX) in patients (pts) with previously treated HER2-positive locally advanced or metastatic gastric/gastroesophageal junction adenocarcinoma (LA/MGC/GEJC). J Clin Oncol 2016;34:abstr 5
-
(2016)
J Clin Oncol
, vol.34
-
-
Kang, Y.K.1
Shah, M.A.2
Ohtsu, A.3
-
41
-
-
84923052492
-
Pertuzumab, trastuzumab, and docetaxel in HER2-positive metastatic breast cancer
-
Swain SM, Baselga J, Kim SB, et al. Pertuzumab, trastuzumab, and docetaxel in HER2-positive metastatic breast cancer. N Engl J Med 2015;372:724-34
-
(2015)
N Engl J Med
, vol.372
, pp. 724-734
-
-
Swain, S.M.1
Baselga, J.2
Kim, S.B.3
-
42
-
-
79955500519
-
Molecular classification of gastric cancer: a new paradigm
-
Shah MA, Khanin R, Tang L, et al. Molecular classification of gastric cancer: a new paradigm. Clin Cancer Res 2011;17:2693-701
-
(2011)
Clin Cancer Res
, vol.17
, pp. 2693-2701
-
-
Shah, M.A.1
Khanin, R.2
Tang, L.3
-
43
-
-
0038745475
-
A combined comparative genomic hybridization and expression microarray analysis of gastric cancer reveals novel molecular subtypes
-
Tay ST, Leong SH, Yu K, et al. A combined comparative genomic hybridization and expression microarray analysis of gastric cancer reveals novel molecular subtypes. Cancer Res 2003;63:3309-16
-
(2003)
Cancer Res
, vol.63
, pp. 3309-3316
-
-
Tay, S.T.1
Leong, S.H.2
Yu, K.3
-
44
-
-
84907270779
-
Comprehensive molecular characterization of gastric adenocarcinoma
-
Cancer Genome Atlas Research Network. Comprehensive molecular characterization of gastric adenocarcinoma. Nature 2014;513:202-9
-
(2014)
Nature
, vol.513
, pp. 202-209
-
-
-
45
-
-
84959474547
-
Clinical impact of tumour biology in the management of gastroesophageal cancer
-
Lordick F, Janjigian YY. Clinical impact of tumour biology in the management of gastroesophageal cancer. Nat Rev Clin Oncol 2016;13:348-60
-
(2016)
Nat Rev Clin Oncol
, vol.13
, pp. 348-360
-
-
Lordick, F.1
Janjigian, Y.Y.2
-
46
-
-
84988314142
-
Genomic profiling of esophagogastric (EG) tumors in clinical practice
-
Riches JC, Schultz N, Ku GY, et al. Genomic profiling of esophagogastric (EG) tumors in clinical practice. J Clin Oncol 2015;33:abstr 57
-
(2015)
J Clin Oncol
, vol.33
-
-
Riches, J.C.1
Schultz, N.2
Ku, G.Y.3
-
47
-
-
84937765053
-
Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes
-
Cristescu R, Lee J, Nebozhyn M, et al. Molecular analysis of gastric cancer identifies subtypes associated with distinct clinical outcomes. Nat Med 2015;21:449-56
-
(2015)
Nat Med
, vol.21
, pp. 449-456
-
-
Cristescu, R.1
Lee, J.2
Nebozhyn, M.3
-
48
-
-
73449130242
-
Oncogenic pathway combinations predict clinical prognosis in gastric cancer
-
Ooi CH, Ivanova T, Wu J, et al. Oncogenic pathway combinations predict clinical prognosis in gastric cancer. PLoS Genet 2009;5:e1000676
-
(2009)
PLoS Genet
, vol.5
-
-
Ooi, C.H.1
Ivanova, T.2
Wu, J.3
-
49
-
-
84958984244
-
Lapatinib in Gastric Cancer: What Is the LOGiCal Next Step?
-
Janjigian YY. Lapatinib in Gastric Cancer: What Is the LOGiCal Next Step? J Clin Oncol 2016;34:401-3
-
(2016)
J Clin Oncol
, vol.34
, pp. 401-403
-
-
Janjigian, Y.Y.1
-
50
-
-
65949099336
-
A primary xenograft model of small-cell lung cancer reveals irreversible changes in gene expression imposed by culture in vitro
-
Daniel VC, Marchionni L, Hierman JS, et al. A primary xenograft model of small-cell lung cancer reveals irreversible changes in gene expression imposed by culture in vitro. Cancer Res 2009;69:3364-73
-
(2009)
Cancer Res
, vol.69
, pp. 3364-3373
-
-
Daniel, V.C.1
Marchionni, L.2
Hierman, J.S.3
-
51
-
-
33645734205
-
Contributions of human tumor xenografts to anticancer drug development
-
discussion 4
-
Sausville EA, Burger AM. Contributions of human tumor xenografts to anticancer drug development. Cancer Res 2006;66:3351-4, discussion 4
-
(2006)
Cancer Res
, vol.66
, pp. 3351-3354
-
-
Sausville, E.A.1
Burger, A.M.2
-
52
-
-
84958971021
-
Patient-derived xenografts as models for the identification of predictive biomarkers in esophagogastric cancer
-
Janjigian YY, Vakiani E, Imtiaz T, et al. Patient-derived xenografts as models for the identification of predictive biomarkers in esophagogastric cancer. J Clin Oncol 2014;32:abstr 4059
-
(2014)
J Clin Oncol
, vol.32
-
-
Janjigian, Y.Y.1
Vakiani, E.2
Imtiaz, T.3
-
53
-
-
84878663006
-
Monitoring afatinib treatment in HER2-positive gastric cancer with 18F-FDG and 89Zr-trastuzumab PET
-
Janjigian YY, Viola-Villegas N, Holland JP, et al. Monitoring afatinib treatment in HER2-positive gastric cancer with 18F-FDG and 89Zr-trastuzumab PET. J Nucl Med 2013;54:936-43
-
(2013)
J Nucl Med
, vol.54
, pp. 936-943
-
-
Janjigian, Y.Y.1
Viola-Villegas, N.2
Holland, J.P.3
-
54
-
-
84940402594
-
A phase II study of afatinib in patients (pts) with metastatic human epidermal growth factor receptor (HER2)-positive trastuzumab refractory esophagogastric (EG) cancer
-
Janjigian YY, Ku GY, Ilson DH, et al. A phase II study of afatinib in patients (pts) with metastatic human epidermal growth factor receptor (HER2)-positive trastuzumab refractory esophagogastric (EG) cancer. J Clin Oncol 2015;33:abstr 59
-
(2015)
J Clin Oncol
, vol.33
-
-
Janjigian, Y.Y.1
Ku, G.Y.2
Ilson, D.H.3
-
55
-
-
77950497981
-
Neratinib, an irreversible ErbB receptor tyrosine kinase inhibitor, in patients with advanced ErbB2-positive breast cancer
-
Burstein HJ, Sun Y, Dirix LY, et al. Neratinib, an irreversible ErbB receptor tyrosine kinase inhibitor, in patients with advanced ErbB2-positive breast cancer. J Clin Oncol 2010;28:1301-7
-
(2010)
J Clin Oncol
, vol.28
, pp. 1301-1307
-
-
Burstein, H.J.1
Sun, Y.2
Dirix, L.Y.3
-
56
-
-
84863169318
-
Evaluation of the antitumor effects and mechanisms of PF00299804, a pan-HER inhibitor, alone or in combination with chemotherapy or targeted agents in gastric cancer
-
Nam HJ, Ching KA, Kan J, et al. Evaluation of the antitumor effects and mechanisms of PF00299804, a pan-HER inhibitor, alone or in combination with chemotherapy or targeted agents in gastric cancer. Mol Cancer Ther 2012;11:439-51
-
(2012)
Mol Cancer Ther
, vol.11
, pp. 439-451
-
-
Nam, H.J.1
Ching, K.A.2
Kan, J.3
-
57
-
-
84947426403
-
Phase II trial of dacomitinib in patients with HER2-positive gastric cancer
-
Oh DY, Lee KW, Cho JY, et al. Phase II trial of dacomitinib in patients with HER2-positive gastric cancer. Gastric Cancer 2016;19:1095-103
-
(2016)
Gastric Cancer
, vol.19
, pp. 1095-1103
-
-
Oh, D.Y.1
Lee, K.W.2
Cho, J.Y.3
-
58
-
-
84899992665
-
Everolimus for women with trastuzumab-resistant, HER2-positive, advanced breast cancer (BOLERO-3): a randomised, double-blind, placebo-controlled phase 3 trial
-
André F, O'Regan R, Ozguroglu M, et al. Everolimus for women with trastuzumab-resistant, HER2-positive, advanced breast cancer (BOLERO-3): a randomised, double-blind, placebo-controlled phase 3 trial. Lancet Oncol 2014;15:580-91
-
(2014)
Lancet Oncol
, vol.15
, pp. 580-591
-
-
André, F.1
O'Regan, R.2
Ozguroglu, M.3
-
59
-
-
23244455101
-
Population pharmacokinetics of trastuzumab in patients with HER2+ metastatic breast cancer
-
Bruno R, Washington CB, Lu JF, et al. Population pharmacokinetics of trastuzumab in patients with HER2+ metastatic breast cancer. Cancer Chemother Pharmacol 2005;56:361-9
-
(2005)
Cancer Chemother Pharmacol
, vol.56
, pp. 361-369
-
-
Bruno, R.1
Washington, C.B.2
Lu, J.F.3
-
60
-
-
85043664418
-
-
Access date: 3rd February 2016. Cited 2016 3rd February 2016
-
Roche Inc: Herceptin package insert. Available online: http://www.medsafe.govt.nz/profs/datasheet/h/Herceptininf.pdf. Access date: 3rd February 2016. Cited 2016 3rd February 2016
-
-
-
|