Tanshinone I alleviates insulin resistance in type 2 diabetes mellitus rats through IRS-1 pathway

Biomedicine and Pharmacotherapy

Volumn 93, Issue , 2017, Pages 352-358

  Wei, Ying ^a   Gao, Jiaqi ^a   Qin, Lingling ^a   Xu, Yunling ^a   Wang, Dongchao ^a   Shi, Haoxia ^a   Xu, Tunhai ^a   Liu, Tonghua ^a  

^a BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

insulin resistance; IRS 1; Tanshinone I; type 2 diabetes

Indexed keywords

CHOLESTEROL; FATTY ACID; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INSULIN RECEPTOR SUBSTRATE 1; INTERLEUKIN 6; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PIOGLITAZONE; STREPTOZOCIN; TANSHINONE I; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR; ABIETANE DERIVATIVE; INSULIN RECEPTOR SUBSTRATE; IRS1 PROTEIN, RAT; TANSHINONE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CHOLESTEROL BLOOD LEVEL; CONTROLLED STUDY; DRUG MECHANISM; DRUG MEGADOSE; ENZYME LINKED IMMUNOSORBENT ASSAY; GLUCOSE BLOOD LEVEL; INSULIN RESISTANCE; LIPID DIET; LOW DRUG DOSE; METABOLIC CLEARANCE RATE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; RAT; SPRAGUE DAWLEY RAT; WESTERN BLOTTING; ANIMAL; CHEMICALLY INDUCED; CHINESE MEDICINE; DRUG EFFECTS; EXPERIMENTAL DIABETES MELLITUS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; PROCEDURES;

ANIMALS; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 2; DIET, HIGH-FAT; DITERPENES, ABIETANE; INSULIN RECEPTOR SUBSTRATE PROTEINS; INSULIN RESISTANCE; INTERLEUKIN-6; MEDICINE, CHINESE TRADITIONAL; NF-KAPPA B; PHOSPHORYLATION; RATS; RATS, SPRAGUE-DAWLEY; STREPTOZOCIN; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85021098009     PISSN: 07533322     EISSN: 19506007     Source Type: Journal    
DOI: 10.1016/j.biopha.2017.06.040     Document Type: Article

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