Critical Illness Myopathy (CIM) and Ventilator-Induced Diaphragm Muscle Dysfunction (VIDD): Acquired myopathies affecting contractile proteins

Comprehensive Physiology

Volumn 7, Issue 1, 2017, Pages 105-112

  Larsson, Lars ^a,b   Friedrich, Oliver ^c  

^a KAROLINSKA INSTITUTE   (Sweden)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c UNIVERSITY OF ERLANGEN NUREMBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CONTRACTILE PROTEIN;

ANIMAL; ARTIFICIAL VENTILATION; CRITICAL ILLNESS; DIAPHRAGM; HUMAN; MUSCLE DISEASE; PATHOPHYSIOLOGY; PHYSIOLOGY;

ANIMALS; CONTRACTILE PROTEINS; CRITICAL ILLNESS; DIAPHRAGM; HUMANS; MUSCULAR DISEASES; RESPIRATION, ARTIFICIAL;

EID: 85020983727     PISSN: None     EISSN: 20404603     Source Type: Journal    
DOI: 10.1002/cphy.c150054     Document Type: Article

References (48)

1. Aare S, Ochala J, Norman HS, Radell P, Eriksson LI, Goransson H, Chen YW, Hoffman EP, Larsson L. Mechanisms underlying the sparing of masticatory versus limb muscle function in an experimental critical illness model. Physiol Genomics 43: 1334-1350, 2011
2. Aare S, Radell P, Eriksson LI, AkkadH, ChenYW, Hoffman EP, Larsson L. Effects of corticosteroids in the development of limbmuscle weakness in a porcine intensive care unit model. Physiol Genomics 45: 312-320, 2013
3. Aare S, Radell P, Eriksson LI, Chen YW, Hoffman EP, Larsson L. Role of sepsis in the development of limb muscle weakness in a porcine intensive care unit model. Physiol Genomics 44: 865-877, 2012
4. Akkad H, Corpeno R, Larsson L. Masseter muscle myofibrillar protein synthesis and degradation in an experimental critical illness myopathy model. PLoS One 9: e92622, 2014
5. Banduseela VC, Ochala J, Chen YW, Goransson H, Norman H, Radell P, Eriksson LI, Hoffman EP, Larsson L. Gene expression and muscle fiber function in a porcine ICU model. Physiol Genomics 39: 141-159, 2009
6. Blake MJ, Fargnoli J, Gershon D, Holbrook NJ. Concomitant decline in heat-induced hyperthermia and HSP70 mRNA expression in aged rats. Am J Physiol 260: R663-667, 1991
7. Chung J, Nguyen AK, Henstridge DC, Holmes AG, Chan MH, Mesa JL, Lancaster GI, Southgate RJ, Bruce CR, Duffy SJ, Horvath I, Mestril R, Watt MJ, Hooper PL, Kingwell BA, Vigh L, Hevener A, Febbraio MA. HSP72 protects against obesity-induced insulin resistance. Proc Natl Acad Sci U S A 105: 1739-1744, 2008
8. Corpeno R, Dworkin B, Cacciani N, Salah H, Bergman HM, Ravara B, Vitadello M, Gorza L, Gustafson AM, Hedstrom Y, Petersson J, Feng HZ, Jin JP, Iwamoto H, Yagi N, Artemenko K, Bergquist J, Larsson L. Time course analysis of mechanical ventilation-induced diaphragm contractile muscle dysfunction in the rat. J Physiol-London 592: 3859-3880, 2014
9. Crul T, Toth N, Piotto S, Literati-Nagy P, Tory K, Haldimann P, Kalmar B, Greensmith L, Torok Z, Balogh G, Gombos I, Campana F, Concilio S, Gallyas F, Nagy G, Berente Z, Gungor B, Peter M, Glatz A, Hunya A, Literati-Nagy Z, Vigh L, Jr., Hoogstra-Berends F, Heeres A, Kuipers I, Loen L, Seerden JP, Zhang D, Meijering RA, Henning RH, Brundel BJ, Kampinga HH, Koranyi L, Szilvassy Z, Mandl J, Sumegi B, Febbraio MA, Horvath I, Hooper PL, Vigh L. Hydroxamic acid derivatives: Pleiotropic HSP co-inducers restoring homeostasis and robustness. Curr Pharm Des 19: 309-346, 2013
10. Di Giovanni S, Molon A, Broccolini A, Melcon G, Mirabella M, Hoffman EP, Servidei S. Constitutive activation of MAPK cascade in acute quadriplegic myopathy. Ann Neurol 55: 195-206, 2004
11. Dodd S, Hain B, Judge A. Hsp70 prevents disuse muscle atrophy in senescent rats. Biogerontology 10: 605-611, 2009
12. Dworkin BR, Dworkin S. Learning of physiological responses: I. Habituation, sensitization, and classical conditioning. Behav Neurosci 104: 298-319, 1990
13. Esteban A, Alia I, Tobin MJ, Gil A, Gordo F, Vallverdu I, Blanch L, Bonet A, Vazquez A, de Pablo R, Torres A, de La Cal MA, Macias S. Effect of spontaneous breathing trial duration on outcome of attempts to discontinue mechanical ventilation. Spanish Lung Failure Collaborative Group. Am J Respir Crit Care Med 159: 512-518, 1999
14. Friedrich O, Fink RH, Hund E. Understanding critical illness myopathy: Approaching the pathomechanism. J Nutr 135: 1813 S-1817 S, 2005
15. Friedrich O, Reid MB, Van den Berghe G, Vanhorebeek I, Hermans G, Rich MM, Larsson L. The sick and the weak: Neuropathies/myopathies in the critically ill. Physiol Rev 95: 1025-1109, 2015
16. Heier CR, Damsker JM, Yu Q, Dillingham BC, Huynh T, Van der Meulen JH, Sali A, Miller BK, PhadkeA, Scheffer L, Quinn J, Tatem K, Jordan S, Dadgar S, Rodriguez OC, Albanese C, Calhoun M, Gordish-Dressman H, Jaiswal JK, Connor EM, McCall JM, Hoffman EP, Reeves EKM, Nagaraju K. VBP15, a novel anti-inflammatory andmembrane-stabilizer, improves muscular dystrophy without side effects. Embo Mol Med 5: 1569-1585, 2013
17. Henstridge DC, Bruce CR, Drew BG, Tory K, Kolonics A, Estevez E, Chung J, Watson N, Gardner T, Lee-Young RS, Connor T, Watt MJ, Carpenter K, Hargreaves M, McGee SL, Hevener AL, Febbraio MA. Activating HSP72 in rodent skeletal muscle increases mitochondrial number and oxidative capacity and decreases insulin resistance. Diabetes 63: 1881-1894, 2014
18. Jaber S, Jung B, Matecki S, Petrof BJ. Clinical review:Ventilator-induced diaphragmatic dysfunction-human studies confirm animal model findings! Crit Care 15: 206, 2011
19. Jaber S, Petrof BJ, Jung B, Chanques G, Berthet JP, Rabuel C, Bouyabrine H, Courouble P, Koechlin-Ramonatxo C, Sebbane M, Similowski T, ScheuermannV, Mebazaa A, Capdevila X, Mornet D, Mercier J, Lacampagne A, Philips A, Matecki S. Rapidly progressive diaphragmatic weakness and injury during mechanical ventilation in humans. Am J Respir Crit Care Med 183: 364-371, 2011
20. Kalamgi RC, Salah H, Gastaldello S, Martinez-Redondo V, Ruas J, Fury W, Bai Y, Gromada J, Sartori R, Guttridge DC, Sandri M, Larsson L. Mechano-signaling pathways in an experimental intensive critical illness myopathy model. J Physiol 594: 4371-4388, 2016
21. Lacomis D, Zochodne DW, Bird SJ. Critical illness myopathy. Muscle Nerve 23: 1785-1788, 2000
22. Larsson L. Experimental animal models of muscle wasting in intensive care unit patients. Crit Care Med 35: S484-487, 2007
23. Larsson L, Li X, Edstrom L, Eriksson LI, Zackrisson H, Argentini C, Schiaffino S. Acute quadriplegia and loss of muscle myosin in patients treated with nondepolarizing neuromuscular blocking agents and corticosteroids: Mechanisms at the cellular and molecular levels [see comments]. Crit Care Med 28: 34-45, 2000
24. Larsson L, Roland A. Drug induced tetraparesis and loss ofmyosin. Mild types are probably overlooked. Lakartidningen 93: 2249-2254, 1996
25. Levine S, Nguyen T, Taylor N, Friscia ME, Budak MT, Rothenberg P, Zhu J, Sachdeva R, Sonnad S, Kaiser LR, Rubinstein NA, Powers SK, Shrager JB. Rapid disuse atrophy of diaphragm fibers in mechanically ventilated humans. N Engl J Med 358: 1327-1335, 2008
26. Lindquist S, Craig EA. The heat-shock proteins. Annu Rev Genet 22: 631-677, 1988
27. Llano-Diez M, Renaud G, Andersson M, Marrero HG, Cacciani N, Engquist H, Corpeno R, Artemenko K, Bergquist J, Larsson L. Mechanisms underlying ICU muscle wasting and effects of passive mechanical loading. Crit Care 16: R209, 2012
28. MacFarlane IA, Rosenthal FD. Severe myopathy after status asthmaticus. Lancet 2: 615, 1977
29. Navalesi P, Frigerio P, Patzlaff A, Haussermann S, Henseke P, Kubitschek M. Prolongedweaning: From the intensive care unit to home. Rev Port Pneumol 20: 264-272, 2014
30. Norman H, Nordquist J, Andersson P, Ansved T, Tang X, Dworkin B, Larsson L. Impact of post-synaptic block of neuromuscular transmission, muscle unloading and mechanical ventilation on skeletal muscle protein and mRNA expression. Pflugers Arch 453: 53-66, 2006
31. Norman H, Zackrisson H, Hedstrom Y, Andersson P, Nordquist J, Eriksson LI, Libelius R, Larsson L. Myofibrillar protein and gene expression in acute quadriplegic myopathy. J Neurol Sci 285: 28-38, 2009
32. Ochala J, Ahlbeck K, Radell PJ, Eriksson LI, Larsson L. Factors underlying the early limb muscle weakness in acute quadriplegic myopathy using an experimental ICU porcine model. PLoS One 6: e20876, 2011
33. Ochala J, Gustafson AM, Diez ML, Renaud G, Li M, Aare S, Qaisar R, Banduseela VC, Hedstrom Y, Tang X, Dworkin B, Ford GC, Nair KS, Perera S, Gautel M, Larsson L. Preferential skeletal muscle myosin loss in response to mechanical silencing in a novel rat intensive care unit model: Underlying mechanisms. J Physiol 589: 2007-2026, 2011
34. Ochala J, Renaud G, Llano Diez M, Banduseela VC, Aare S, Ahlbeck K, Radell PJ, Eriksson LI, Larsson L. Diaphragm muscle weakness in an experimental porcine intensive care unit model. PLoS One 6: e20558, 2011
35. Ogilvie H, Cacciani N, Akkad H, Larsson L. Targeting heat shock proteins mitigates ventilator induced diaphragm muscle dysfunction in an age-dependent manner. Front Physiol. In press: 2016
36. Petrof BJ, Jaber S, Matecki S. Ventilator-induced diaphragmatic dysfunction. Curr Opin Crit Care 16: 19-25, 2010
37. Renaud G, Llano-Diez M, Ravara B, Gorza L, Feng HZ, Jin JP, Cacciani N, Gustafson AM, Ochala J, Corpeno R, Li M, Hedstrom Y, Ford GC, Nair KS, Larsson L. Sparing of muscle mass and function by passive loading in an experimental intensive care unit model. J Physiol 591: 1385-1402, 2013
38. Rich MM, Teener JW, Raps EC, Schotland DL, Bird SJ. Muscle is electrically inexcitable in acute quadriplegic myopathy. Neurology 46: 731-736, 1996
39. Rudis MI, Guslits BJ, Peterson EL, Hathaway SJ, Angus E, Beis S, Zarowitz BJ. Economic impact of prolonged motor weakness complicating neuromuscular blockade in the intensive care unit. Crit Care Med 24: 1749-1756, 1996
40. Salah H, Li M, Cacciani N, Gastaldello S, Ogilvie H, Akkad H, Venkant Namaduri A, Morbidino V, Artemenko K, Balogh G, Martinez-Redondo V, Hedström Y, Dworkin B, Bergquist J, Ruas J, Vigh L, Salviati L, Larsson L. The chaperone co-inducer BGP-15 alleviates ventilation induced diaphragm dysfunction. Sci Transl Med 2016 Aug 3;8(350):350ra103. doi:10. 1126/scitranslmed. aaf7099
41. Schefold JC, Bierbrauer J, Weber-Carstens S. Intensive care unitacquired weakness (ICUAW) and muscle wasting in critically ill patients with severe sepsis and septic shock. J Cachexia Sarcopenia Muscle 1: 147-157, 2010
42. Seneff MG, Wagner D, Thompson D, Honeycutt C, Silver MR. The impact of long-term acute-care facilities on the outcome and cost of care for patients undergoing prolonged mechanical ventilation. Crit Care Med 28: 342-350, 2000
43. Senf SM, Dodd SL, McClung JM, Judge AR. Hsp70 overexpression inhibits NF-kappaB and Foxo3 a transcriptional activities and prevents skeletal muscle atrophy. FASEB J 22: 3836-3845, 2008
44. Supinski GS, Callahan LA. Diaphragm weakness in mechanically ventilated critically ill patients. Crit Care 17: R120, 2013
45. Vaillancourt JP, Lyons C, Cote G. Identification of two phosphorylated threonines in the tail region of Dictyostelium myosin II. J Biol Chem 263: 10082-10087, 1988
46. Vallverdu I, Calaf N, Subirana M, Net A, Benito S, Mancebo J. Clinical characteristics, respiratory functional parameters, and outcome of a twohour T-piece trial in patients weaning from mechanical ventilation. Am J Respir Crit Care Med 158: 1855-1862, 1998
47. Vincent JL. Critical care-where have we been and where are we going? Crit Care 17(Suppl 1): S2, 2013
48. Zilberberg MD, Shorr AF. Prolonged acute mechanical ventilation and hospital bed utilization in 2020 in the United States: Implications for budgets, plant and personnel planning. BMC Health Serv Res 8: 242, 2008