Estimation in multi-arm two-stage trials with treatment selection and time-to-event endpoint

Statistics in Medicine

Volumn 36, Issue 20, 2017, Pages 3137-3153

  Brückner, Matthias ^a   Titman, Andrew ^a   Jaki, Thomas ^a  

^a LANCASTER UNIVERSITY   (United Kingdom)

Author keywords

adaptive design; bias; empirical Bayes; multi arm trial; time to event

Indexed keywords

HUMAN; SELECTION BIAS; SIMULATION; THEORETICAL MODEL; ADAPTIVE CLINICAL TRIAL (TOPIC); BAYES THEOREM; BIOSTATISTICS; CLINICAL TRIAL (TOPIC); COLORECTAL TUMOR; COMPUTER SIMULATION; CONFIDENCE INTERVAL; CONTROLLED CLINICAL TRIAL (TOPIC); KAPLAN MEIER METHOD; STATISTICAL MODEL; STATISTICS AND NUMERICAL DATA; TIME FACTOR;

ADAPTIVE CLINICAL TRIALS AS TOPIC; BAYES THEOREM; BIOSTATISTICS; CLINICAL TRIALS AS TOPIC; COLORECTAL NEOPLASMS; COMPUTER SIMULATION; CONFIDENCE INTERVALS; CONTROLLED CLINICAL TRIALS AS TOPIC; HUMANS; KAPLAN-MEIER ESTIMATE; LIKELIHOOD FUNCTIONS; SELECTION BIAS; TIME FACTORS;

EID: 85020407913     PISSN: 02776715     EISSN: 10970258     Source Type: Journal    
DOI: 10.1002/sim.7367     Document Type: Article

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