Sequential designs for phase III clinical trials incorporating treatment selection

Statistics in Medicine

Volumn 22, Issue 5, 2003, Pages 689-703

  Stallard, Nigel ^a   Todd, Susan ^a  

^a UNIVERSITY OF READING   (United Kingdom)

Author keywords

Group sequential test; Phase II III trial; Screening design; Select and test design; Spending functions

Indexed keywords

GALANTAMINE; NEW DRUG; PLACEBO;

ALZHEIMER DISEASE; ANALYTICAL ERROR; CLINICAL STUDY; CLINICAL TRIAL; COMPARATIVE STUDY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; COVARIANCE; DRUG APPROVAL; EXPERIMENTAL DESIGN; HUMAN; MAJOR CLINICAL STUDY; PHASE 3 CLINICAL TRIAL; RANDOMIZED CONTROLLED TRIAL; REVIEW; SAMPLE SIZE; SEQUENTIAL ANALYSIS; STATISTICAL ANALYSIS;

ALZHEIMER DISEASE; CHOLINESTERASE INHIBITORS; CLINICAL TRIALS, PHASE II; CLINICAL TRIALS, PHASE III; COGNITION; COMPUTER SIMULATION; DATA INTERPRETATION, STATISTICAL; DRUG APPROVAL; GALANTAMINE; HUMANS; RESEARCH DESIGN;

EID: 0037445466     PISSN: 02776715     EISSN: None     Source Type: Journal    
DOI: 10.1002/sim.1362     Document Type: Review

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