Isolation of T-cell receptors specifically reactive with mutated tumor-associated antigens from tumor-infiltrating lymphocytes based on CD137 expression

Clinical Cancer Research

Volumn 23, Issue 10, 2017, Pages 2491-2505

  Parkhurst, Maria ^a   Gros, Alena ^a   Pasetto, Anna ^a   Prickett, Todd ^a   Crystal, Jessica S ^a   Robbins, Paul ^a   Rosenberg, Steven A ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; CD137 ANTIGEN; CD8 ANTIGEN; COMPLEMENTARY DNA; GAMMA INTERFERON; GENOMIC DNA; MESSENGER RNA; RETROVIRUS VECTOR; T LYMPHOCYTE RECEPTOR; T LYMPHOCYTE RECEPTOR ALPHA CHAIN; T LYMPHOCYTE RECEPTOR BETA CHAIN; TUMOR ANTIGEN; LYMPHOCYTE ANTIGEN RECEPTOR; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 9;

ADOPTIVE IMMUNOTHERAPY; AMINO ACID SEQUENCE; ANTIGEN EXPRESSION; ANTIGEN RECOGNITION; ARTICLE; AUTOTRANSPLANTATION; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL SELECTION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; DNA MODIFICATION; DNA SEQUENCE; GENE CONSTRUCT; GENE PRODUCT; GENE SYNTHESIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOREACTIVITY; IN VITRO GENE TRANSFER; IN VITRO STUDY; LYMPHOCYTE CULTURE; LYMPHOCYTE TRANSFER; MUTATIONAL ANALYSIS; NONHUMAN; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN ISOLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA SEQUENCE; SEQUENCE ANALYSIS; SINGLE CELL ANALYSIS; SOMATIC MUTATION; T LYMPHOCYTE; TUMOR ASSOCIATED LEUKOCYTE; VIRAL GENE DELIVERY SYSTEM; WHOLE EXOME SEQUENCING; ADOPTIVE TRANSFER; EXOME; GENE EXPRESSION REGULATION; GENETICS; HIGH THROUGHPUT SEQUENCING; IMMUNOLOGY; MELANOMA; MUTATION; PROCEDURES;

ADOPTIVE TRANSFER; ANTIGENS, NEOPLASM; CD8-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; EXOME; GENE EXPRESSION REGULATION, NEOPLASTIC; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; IMMUNOTHERAPY, ADOPTIVE; LYMPHOCYTES, TUMOR-INFILTRATING; MELANOMA; MUTATION; RECEPTORS, ANTIGEN, T-CELL; RNA, MESSENGER; TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY, MEMBER 9;

EID: 85020385407     PISSN: 10780432     EISSN: 15573265     Source Type: Journal    
DOI: 10.1158/1078-0432.CCR-16-2680     Document Type: Article

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