Contribution of Malabsorption to Weight Loss After Roux-en-Y Gastric Bypass: a Systematic Review

Obesity Surgery

Volumn 27, Issue 8, 2017, Pages 2194-2206

  Mahawar, Kamal K ^a   Sharples, Alistair J ^b  

^a SUNDERLAND ROYAL HOSPITAL   (United Kingdom)

^b UNIVERSITY HOSPITALS OF NORTH MIDLANDS NHS TRUST   (United Kingdom)

Author keywords

Absorption; Carbohydrate; Fat; Gastric bypass; Malabsorption; Malabsorptive; Protein; Roux en Y gastric bypass

Indexed keywords

CARBOHYDRATE; FAT; PROTEIN;

ABSORPTION; CALORIE MALABSORPTION; CARBOHYDRATE ABSORPTION; HUMAN; LIPID ABSORPTION; MACRONUTRIENT; MALABSORPTION; META ANALYSIS; PRIORITY JOURNAL; PROTEIN ABSORPTION; REVIEW; ROUX-EN-Y GASTRIC BYPASS; SYSTEMATIC REVIEW; WEIGHT REDUCTION; ADVERSE EFFECTS; GASTRIC BYPASS SURGERY; MALABSORPTION SYNDROMES; OBESITY, MORBID;

GASTRIC BYPASS; HUMANS; MALABSORPTION SYNDROMES; OBESITY, MORBID; WEIGHT LOSS;

EID: 85020211919     PISSN: 09608923     EISSN: 17080428     Source Type: Journal    
DOI: 10.1007/s11695-017-2762-y     Document Type: Review

References (36)

1. Angrisani L, Santonicola A, Iovino P, et al. Bariatric surgery and endoluminal procedures: IFSO worldwide survey 2014. Obes Surg. 2017; doi:10.1007/s11695-017-2666-x.
2. Welbourn R, Small P, Finlay I, Sarela A, Somers S, Mahawar K. Second National Bariatric Surgery Report. http://www.bomss.org.uk/wp-content/uploads/2014/04/Extract_from_the_NBSR_2014_Report.pdf Last Accessed on 22nd March ’ 2017
3. Seeley RJ, Chambers AP, Sandoval DA. The role of gut adaptation in the potent effects of multiple bariatric surgeries on obesity and diabetes. Cell Metab. 2015;21(3):369–78.
4. O’Brien PE. Bariatric surgery: mechanisms, indications and outcomes. J Gastroenterol Hepatol. 2010;25(8):1358–65.
5. Miras AD, le Roux CW. Mechanisms underlying weight loss after bariatric surgery. Nat Rev Gastroenterol Hepatol. 2013;10(10):575–84.
6. Mahawar KK, Kumar P, Parmar C, et al. Small bowel limb lengths and Roux-en-Y gastric bypass: a systematic review. Obes Surg. 2016;26(3):660–71.
7. Pihlajamäki J, Grönlund S, Simonen M, et al. Cholesterol absorption decreases after Roux-en-Y gastric bypass but not after gastric banding. Metabolism. 2010;59(6):866–72.
8. Carswell KA, Vincent RP, Belgaumkar AP, et al. The effect of bariatric surgery on intestinal absorption and transit time. Obes Surg. 2014;24(5):796–805.
9. Odstrcil EA, Martinez JG, Santa Ana CA, et al. The contribution of malabsorption to the reduction in net energy absorption after long- limb Roux-en-Y gastric bypass. Am J Clin Nutr. 2010;92:704–13.
10. Moreland AM, Santa Ana CA, Asplin JR, et al. Steatorrhea and hyperoxaluria in severely obese patients before and after Roux-en-Y gastric bypass. Gastroenterology. 2017;152(5):1055–1067.e3.
11. Griffo E, Nosso G, Lupoli R, et al. Early improvement of postprandial lipemia after bariatric surgery in obese type 2 diabetic patients. Obes Surg. 2014;24(5):765–70.
12. Borbély Y, Plebani A, Kröll D, et al. Exocrine pancreatic insufficiency after Roux-en-Y gastric bypass. Surg Obes Relat dis. 2016;12(4):790–4.
13. Kumar R, Lieske JC, Collazo-Clavell ML, et al. Fat malabsorption and increased intestinal oxalate absorption are common after Roux- en-Y gastric bypass surgery. Surgery. 2011;149(5):654–61.
14. Forbes R, Gasevic D, Watson EM, et al. Essential fatty acid plasma profiles following gastric bypass and adjusted gastric banding bariatric surgeries. Obes Surg. 2016;26(6):1237–46.
15. Bojsen-Møller KN, Jacobsen SH, Dirksen C, et al. Accelerated protein digestion and amino acid absorption after Roux-en-Y gastric bypass. Am J Clin Nutr. 2015;102(3):600–7.
16. Khoo CM, Muehlbauer MJ, Stevens RD, et al. Postprandial metabolite profiles reveal differential nutrient handling after bariatric surgery compared with matched caloric restriction. Ann Surg. 2014;259(4):687–93.
17. Laferrère B, Reilly D, Arias S, et al. Differential metabolic impact of gastric bypass surgery versus dietary intervention in obese diabetic subjects despite identical weight loss. Sci Transl Med. 2011;3(80):80re2.
18. Andalib I, Shah H, Bal BS, et al. Breath hydrogen as a biomarker for glucose malabsorption after Roux-en-Y gastric bypass surgery. Dis Markers. 2015;2015:102760.
19. Nguyen NQ, Debreceni TL, Bambrick JE, et al. Rapid gastric and intestinal transit is a major determinant of changes in blood glucose, intestinal hormones, glucose absorption and postprandial symptoms after gastric bypass. Obesity (Silver Spring). 2014;22(9):2003–9.
20. Nguyen NQ, Debreceni TL, Bambrick JE, et al. Upregulation of intestinal glucose transporters after Roux-en-Y gastric bypass to prevent carbohydrate malabsorption. Obesity (Silver Spring). 2014;22(10):2164–71.
21. Anderwald CH, Tura A, Promintzer-Schifferl M, et al. Alterations in gastrointestinal, endocrine, and metabolic processes after bariatric Roux-en-Y gastric bypass surgery. Diabetes Care. 2012;35(12):2580–7.
22. Jacobsen SH, Bojsen-Møller KN, Dirksen C, et al. Effects of gastric bypass surgery on glucose absorption and metabolism during a mixed meal in glucose-tolerant individuals. Diabetologia. 2013;56(10):2250–4.
23. Camastra S, Muscelli E, Gastaldelli A, et al. Long-term effects of bariatric surgery on meal disposal and β-cell function in diabetic and nondiabetic patients. Diabetes. 2013;62(11):3709–17.
24. Falkén Y, Hellström PM, Holst JJ, et al. Changes in glucose homeostasis after Roux-en-Y gastric bypass surgery for obesity at day three, two months, and one year after surgery: role of gut peptides. J Clin Endocrinol Metab. 2011;96(7):2227–35.
25. Rodieux F, Giusti V, D’Alessio DA, et al. Effects of gastric bypass and gastric banding on glucose kinetics and gut hormone release. Obesity (Silver Spring). 2008;16(2):298–305.
26. Wang G, Agenor K, Pizot J, et al. Accelerated gastric emptying but no carbohydrate malabsorption 1 year after gastric bypass surgery (GBP). Obes Surg. 2012;22(8):1263–7.
27. Wilms B, Ernst B, Schmid SM, et al. Enhanced thermic effect of food after Roux-en-Y gastric bypass surgery. J Clin Endocrinol Metab. 2013;98(9):3776–84.
28. Savassi-Rocha AL, Diniz MT, Vilela EG, et al. Changes in intestinal permeability after Roux-en-Y gastric bypass. Obes Surg. 2014;24(2):184–90.
29. Caruana JA, Monte SV, Jacobs DM, et al. Distal small bowel bypass for weight regain after gastric bypass: safety and efficacy threshold occurs at <70% bypass. Surg Obes Relat dis. 2015;11(6):1248–55.
30. Manning S, Pucci A, Batterham RL. Roux-en-Y gastric bypass: effects on feeding behavior and underlying mechanisms. J Clin Invest. 2015;125(3):939–48.
31. Bradley 3rd EL, Isaacs JT, Mazo JD, et al. Pathophysiology and significance of malabsorption after Roux-en-Y reconstruction. Surgery. 1977;81(6):684–91.
32. Cosnes J, Lamy P, Beaugerie L, et al. Adaptive hyperphagia in patients with postsurgical malabsorption. Gastroenterology. 1990;99(6):1814–9.
33. le Roux CW, Bueter M. The physiology of altered eating behaviour after Roux-en-Y gastric bypass. Exp Physiol. 2014;99:1128–32.
34. Flancbaum L, Choban PS, Bradley LR, et al. Changes in measured resting energy expenditure after Roux-en-Y gastric bypass for clinically severe obesity. Surgery. 1997;122(5):943–9.
35. Borg CM, le Roux CW, Ghatei MA, et al. Progressive rise in gut hormone levels after Roux-en-Y gastric bypass suggests gut adaptation and explains altered satiety. Br J Surg. 2006;93(2):210–5.
36. Savassi-Rocha AL, Diniz MT, Savassi-Rocha PR, et al. Influence of jejunoileal and common limb length on weight loss following Roux-en- Y gastric bypass. Obes Surg. 2008;18(11):1364–8.