메뉴 건너뛰기




Volumn 546, Issue 7656, 2017, Pages 168-172

Author Correction: CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells (Nature, (2017), 546, 7656, (168-172), 10.1038/nature22359);CPS1 maintains pyrimidine pools and DNA synthesis in KRAS/LKB1-mutant lung cancer cells

(26)  Kim, Jiyeon a   Hu, Zeping a   Cai, Ling a   Li, Kailong a   Choi, Eunhee b   Faubert, Brandon a   Bezwada, Divya a   Rodriguez Canales, Jaime c   Villalobos, Pamela c   Lin, Yu Fen b   Ni, Min a   Huffman, Kenneth E a   Girard, Luc a   Byers, Lauren A c   Unsal Kacmaz, Keziban d   Peña, Christopher G b,h   Heymach, John V c   Wauters, Els e   Vansteenkiste, Johan e   Castrillon, Diego H b   more..


Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; ARGININOSUCCINATE SYNTHASE; BETA ACTIN; CARBAMOYL PHOSPHATE; CARBAMOYL PHOSPHATE SYNTHASE; CASPASE ACTIVATED DEOXYRIBONUCLEASE; CISPLATIN; CITRULLINE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; DNA POLYMERASE; DOXYCYCLINE; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; HEPATOCYTE NUCLEAR FACTOR 3ALPHA; HISTONE H2AX; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE KINASE; K RAS PROTEIN; MESSENGER RNA; ORNITHINE; ORNITHINE DECARBOXYLASE; PROTEIN; PROTEIN KINASE LKB1; PYRIMIDINE; RENILLA LUCIFERIN 2 MONOOXYGENASE; SHORT HAIRPIN RNA; SMALL INTERFERING RNA; SODIUM NITRITE; THYMIDINE; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR TEAD4; UNCLASSIFIED DRUG; URIDINE; AMMONIA; BICARBONATE; DNA; DNA DIRECTED DNA POLYMERASE; KRAS PROTEIN, HUMAN; NITROGEN; PROTEIN P21; PROTEIN SERINE THREONINE KINASE; PURINE; PURINE DERIVATIVE; PYRIMIDINE DERIVATIVE; STK11 PROTEIN, HUMAN;

EID: 85020182527     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/s41586-019-1133-3     Document Type: Erratum
Times cited : (220)

References (30)
  • 1
    • 84941728686 scopus 로고    scopus 로고
    • Immunohistochemical loss of lkb1 is a biomarker for more aggressive biology in kras-mutant lung adenocarcinoma
    • Calles, A. et al. Immunohistochemical loss of LKB1 is a biomarker for more aggressive biology in KRAS-mutant lung adenocarcinoma. Clin. Cancer Res. 21, 2851-2860 (2015).
    • (2015) Clin. Cancer Res , vol.21 , pp. 2851-2860
    • Calles, A.1
  • 2
    • 34547926839 scopus 로고    scopus 로고
    • Lkb1 modulates lung cancer differentiation and metastasis
    • Ji, H. et al. LKB1 modulates lung cancer differentiation and metastasis. Nature 448, 807-810 (2007).
    • (2007) Nature , vol.448 , pp. 807-810
    • Ji, H.1
  • 3
    • 84881508779 scopus 로고    scopus 로고
    • Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in lkb1-mutant lung cancer
    • Liu, Y. et al. Metabolic and functional genomic studies identify deoxythymidylate kinase as a target in LKB1-mutant lung cancer. Cancer Discov. 3, 870-879 (2013).
    • (2013) Cancer Discov , vol.3 , pp. 870-879
    • Liu, Y.1
  • 4
    • 84886787846 scopus 로고    scopus 로고
    • Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer
    • Kim, H. S. et al. Systematic identification of molecular subtype-selective vulnerabilities in non-small-cell lung cancer. Cell 155, 552-566 (2013).
    • (2013) Cell , vol.155 , pp. 552-566
    • Kim, H.S.1
  • 5
    • 79951830082 scopus 로고    scopus 로고
    • DNA methylation suppresses expression of the urea cycle enzyme carbamoyl phosphate synthetase 1 (cps1) in human hepatocellular carcinoma
    • Liu, H., Dong, H., Robertson, K. & Liu, C. DNA methylation suppresses expression of the urea cycle enzyme carbamoyl phosphate synthetase 1 (CPS1) in human hepatocellular carcinoma. Am. J. Pathol. 178, 652-661 (2011).
    • (2011) Am. J. Pathol , vol.178 , pp. 652-661
    • Liu, H.1    Dong, H.2    Robertson, K.3    Liu, C.4
  • 6
    • 84947745250 scopus 로고    scopus 로고
    • Diversion of aspartate in ass1-deficient tumours fosters de novo pyrimidine synthesis
    • Rabinovich, S. et al. Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis. Nature 527, 379-383 (2015).
    • (2015) Nature , vol.527 , pp. 379-383
    • Rabinovich, S.1
  • 7
    • 85018160687 scopus 로고    scopus 로고
    • Role of cps1 in cell growth, metabolism, and prognosis in lkb1-inactivated lung adenocarcinoma
    • Celiktas, M. et al. Role of CPS1 in cell growth, metabolism, and prognosis in LKB1-inactivated lung adenocarcinoma. J. Natl. Cancer Inst. 109, 1-9 (2016).
    • (2016) J. Natl. Cancer Inst , vol.109 , pp. 1-9
    • Celiktas, M.1
  • 8
    • 67749111502 scopus 로고    scopus 로고
    • The lkb1-Ampk pathway: Metabolism and growth control in tumour suppression
    • Shackelford, D. B. & Shaw, R. J. The LKB1-AMPK pathway: metabolism and growth control in tumour suppression. Nat. Rev. Cancer 9, 563-575 (2009).
    • (2009) Nat. Rev. Cancer , vol.9 , pp. 563-575
    • Shackelford, D.B.1    Shaw, R.J.2
  • 9
    • 84858782079 scopus 로고    scopus 로고
    • Ampk: A nutrient and energy sensor that maintains energy homeostasis
    • Hardie, D. G., Ross, F. A. & Hawley, S. A. AMPK: a nutrient and energy sensor that maintains energy homeostasis. Nat. Rev. Mol. Cell Biol. 13, 251-262 (2012).
    • (2012) Nat. Rev. Mol. Cell Biol , vol.13 , pp. 251-262
    • Hardie, D.G.1    Ross, F.A.2    Hawley, S.A.3
  • 10
    • 84925970129 scopus 로고    scopus 로고
    • Cellular energy stress induces ampk-mediated regulation of yap and the hippo pathway
    • Mo, J.-S. et al. Cellular energy stress induces AMPK-mediated regulation of YAP and the Hippo pathway. Nat. Cell Biol. 17, 500-510 (2015).
    • (2015) Nat. Cell Biol , vol.17 , pp. 500-510
    • Mo, J.-S.1
  • 11
    • 84968571741 scopus 로고    scopus 로고
    • Metformin induces apoptosis of human hepatocellular carcinoma hepg2 cells by activating an ampk/p53/mir-23a/foxa1 pathway
    • Sun, Y. et al. Metformin induces apoptosis of human hepatocellular carcinoma HepG2 cells by activating an AMPK/p53/miR-23a/FOXA1 pathway. Onco Targets Ther. 9, 2845-2853 (2016).
    • (2016) Onco Targets Ther , vol.9 , pp. 2845-2853
    • Sun, Y.1
  • 12
    • 79551489371 scopus 로고    scopus 로고
    • Metformin inhibits p-glycoprotein expression via the nf-? B pathway and cre transcriptional activity through ampk activation
    • Kim, H. G. et al. Metformin inhibits P-glycoprotein expression via the NF-? B pathway and CRE transcriptional activity through AMPK activation. Br. J. Pharmacol. 162, 1096-1108 (2011).
    • (2011) Br. J. Pharmacol , vol.162 , pp. 1096-1108
    • Kim, H.G.1
  • 13
    • 0024507871 scopus 로고
    • Mapping of the gene encoding the multifunctional protein carrying out the first three steps of pyrimidine biosynthesis to human chromosome 2
    • Chen, K. C., Vannais, D. B., Jones, C., Patterson, D. & Davidson, J. N. Mapping of the gene encoding the multifunctional protein carrying out the first three steps of pyrimidine biosynthesis to human chromosome 2. Hum. Genet. 82, 40-44 (1989).
    • (1989) Hum. Genet , vol.82 , pp. 40-44
    • Chen, K.C.1    Vannais, D.B.2    Jones, C.3    Patterson, D.4    Davidson, J.N.5
  • 14
    • 0025129245 scopus 로고
    • Mammalian dihydroorotase: Nucleotide sequence, peptide sequences, and evolution of the dihydroorotase domain of the multifunctional protein cad
    • Simmer, J. P. et al. Mammalian dihydroorotase: nucleotide sequence, peptide sequences, and evolution of the dihydroorotase domain of the multifunctional protein CAD. Proc. Natl Acad. Sci. USA 87, 174-178 (1990).
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 174-178
    • Simmer, J.P.1
  • 15
    • 84874995247 scopus 로고    scopus 로고
    • Stimulation of de novo pyrimidine synthesis by growth signaling through mtor and s6k1
    • Ben-Sahra, I., Howell, J. J., Asara, J. M. & Manning, B. D. Stimulation of de novo pyrimidine synthesis by growth signaling through mTOR and S6K1. Science 339, 1323-1328 (2013).
    • (2013) Science , vol.339 , pp. 1323-1328
    • Ben-Sahra, I.1    Howell, J.J.2    Asara, J.M.3    Manning, B.D.4
  • 16
    • 0034747043 scopus 로고    scopus 로고
    • Ornithine carbamoyltransferase deficiency
    • Wraith, J. E. Ornithine carbamoyltransferase deficiency. Arch. Dis. Child. 84, 84-88 (2001).
    • (2001) Arch. Dis. Child , vol.84 , pp. 84-88
    • Wraith, J.E.1
  • 17
    • 84857060479 scopus 로고    scopus 로고
    • Dntp pools determine fork progression and origin usage under replication stress
    • Poli, J. et al. dNTP pools determine fork progression and origin usage under replication stress. EMBO J. 31, 883-894 (2012).
    • (2012) EMBO J , vol.31 , pp. 883-894
    • Poli, J.1
  • 18
    • 0042743766 scopus 로고    scopus 로고
    • Dynamics of DNA replication in mammalian somatic cells: Nucleotide pool modulates origin choice and interorigin spacing
    • Anglana, M., Apiou, F., Bensimon, A. & Debatisse, M. Dynamics of DNA replication in mammalian somatic cells: nucleotide pool modulates origin choice and interorigin spacing. Cell 114, 385-394 (2003).
    • (2003) Cell , vol.114 , pp. 385-394
    • Anglana, M.1    Apiou, F.2    Bensimon, A.3    Debatisse, M.4
  • 19
    • 76849109722 scopus 로고    scopus 로고
    • Hydroxyureastalled replication forks become progressively inactivated and require two different rad51-mediated pathways for restart and repair
    • Petermann, E., Orta, M. L., Issaeva, N., Schultz, N. & Helleday, T. Hydroxyureastalled replication forks become progressively inactivated and require two different RAD51-mediated pathways for restart and repair. Mol. Cell 37, 492-502 (2010).
    • (2010) Mol. Cell , vol.37 , pp. 492-502
    • Petermann, E.1    Orta, M.L.2    Issaeva, N.3    Schultz, N.4    Helleday, T.5
  • 20
    • 34047094441 scopus 로고    scopus 로고
    • Replication fork barriers: Pausing for a break or stalling for time?
    • Labib, K. & Hodgson, B. Replication fork barriers: pausing for a break or stalling for time? EMBO Rep. 8, 346-353 (2007).
    • (2007) EMBO Rep , vol.8 , pp. 346-353
    • Labib, K.1    Hodgson, B.2
  • 21
    • 0023925454 scopus 로고
    • Interactions between deoxyribonucleotide and DNA synthesis
    • Reichard, P. Interactions between deoxyribonucleotide and DNA synthesis. Annu. Rev. Biochem. 57, 349-374 (1988).
    • (1988) Annu. Rev. Biochem , vol.57 , pp. 349-374
    • Reichard, P.1
  • 22
    • 84873584845 scopus 로고    scopus 로고
    • Lkb1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin
    • Shackelford, D. B. et al. LKB1 inactivation dictates therapeutic response of non-small cell lung cancer to the metabolism drug phenformin. Cancer Cell 23, 143-158 (2013).
    • (2013) Cancer Cell , vol.23 , pp. 143-158
    • Shackelford, D.B.1
  • 23
    • 84875894714 scopus 로고    scopus 로고
    • Glutamine supports pancreatic cancer growth through a kras-regulated metabolic pathway
    • Son, J. et al. Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway. Nature 496, 101-105 (2013).
    • (2013) Nature , vol.496 , pp. 101-105
    • Son, J.1
  • 24
    • 84902343371 scopus 로고    scopus 로고
    • Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects
    • Mullen, A. R. et al. Oxidation of alpha-ketoglutarate is required for reductive carboxylation in cancer cells with mitochondrial defects. Cell Rep. 7, 1679-1690 (2014).
    • (2014) Cell Rep , vol.7 , pp. 1679-1690
    • Mullen, A.R.1
  • 25
    • 70350217425 scopus 로고    scopus 로고
    • Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or akt signaling
    • Yang, C. et al. Glioblastoma cells require glutamate dehydrogenase to survive impairments of glucose metabolism or Akt signaling. Cancer Res. 69, 7986-7993 (2009).
    • (2009) Cancer Res , vol.69 , pp. 7986-7993
    • Yang, C.1
  • 26
    • 0032559794 scopus 로고    scopus 로고
    • Replicon clusters are stable units of chromosome structure: Evidence that nuclear organization contributes to the efficient activation and propagation of s phase in human cells
    • Jackson, D. A. & Pombo, A. Replicon clusters are stable units of chromosome structure: evidence that nuclear organization contributes to the efficient activation and propagation of S phase in human cells. J. Cell Biol. 140, 1285-1295 (1998).
    • (1998) J. Cell Biol , vol.140 , pp. 1285-1295
    • Jackson, D.A.1    Pombo, A.2
  • 27
    • 84958739420 scopus 로고    scopus 로고
    • Dynamic control of enhancer repertoires drives lineage and stage-specific transcription during hematopoiesis
    • Huang, J. et al. Dynamic control of enhancer repertoires drives lineage and stage-specific transcription during hematopoiesis. Dev. Cell 36, 9-23 (2016).
    • (2016) Dev. Cell , vol.36 , pp. 9-23
    • Huang, J.1
  • 28
    • 84887010498 scopus 로고    scopus 로고
    • Genome engineering using the crispr-cas9 system
    • Ran, F. A. et al. Genome engineering using the CRISPR-Cas9 system. Nat. Protoc. 8, 2281-2308 (2013).
    • (2013) Nat. Protoc , vol.8 , pp. 2281-2308
    • Ran, F.A.1
  • 29
    • 84892765883 scopus 로고    scopus 로고
    • Genome-scale crispr-cas9 knockout screening in human cells
    • Shalem, O. et al. Genome-scale CRISPR-Cas9 knockout screening in human cells. Science 343, 84-87 (2014).
    • (2014) Science , vol.343 , pp. 84-87
    • Shalem, O.1
  • 30
    • 84905029258 scopus 로고    scopus 로고
    • Comprehensive molecular profiling of lung adenocarcinoma
    • Cancer Genome Atlas Research Network
    • Cancer Genome Atlas Research Network. Comprehensive molecular profiling of lung adenocarcinoma. Nature 511, 543-550 (2014).
    • (2014) Nature , vol.511 , pp. 543-550


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.