Activated Platelets Induce an Anti-Inflammatory Response of Monocytes/Macrophages through Cross-Regulation of PGE2 and Cytokines

Mediators of Inflammation

Volumn 2017, Issue , 2017, Pages

  Linke, Bona ^a   Schreiber, Yannick ^a   Picard Willems, Bettina ^a   Slattery, Patrick ^a   Nüsing, Rolf M ^a   Harder, Sebastian ^b   Geisslinger, Gerd ^a   Scholich, Klaus ^a  

^a UNIVERSITY HOSPITAL FRANKFURT   (Germany)

^b FRAUNHOFER INSTITUTE FOR MOLECULAR BIOLOGY AND APPLIED ECOLOGY IME   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

BUTAPROST; CYTOKINE; INTERLEUKIN 10; INTERLEUKIN 10 RECEPTOR; PROSTAGLANDIN E RECEPTOR 2; PROSTAGLANDIN E RECEPTOR 4; PROSTAGLANDIN E2; TUMOR NECROSIS FACTOR;

ANIMAL CELL; ARTICLE; BONE MARROW DERIVED MACROPHAGE; CELL LYSATE; COCULTURE; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; EC50; EX VIVO STUDY; HUMAN; HUMAN CELL; INFLAMMATION; MONOCYTE; MOUSE; NONHUMAN; PROSTAGLANDIN RELEASE; THROMBOCYTE ACTIVATION; THROMBOCYTE RICH PLASMA; ANIMAL; C57BL MOUSE; GENETICS; MACROPHAGE; METABOLISM; THROMBOCYTE;

ANIMALS; BLOOD PLATELETS; CYTOKINES; HUMANS; INFLAMMATION; INTERLEUKIN-10; MACROPHAGES; MICE; MICE, INBRED C57BL; MONOCYTES; RECEPTORS, PROSTAGLANDIN E, EP2 SUBTYPE; TUMOR NECROSIS FACTOR-ALPHA;

EID: 85020045614     PISSN: 09629351     EISSN: 14661861     Source Type: Journal    
DOI: 10.1155/2017/1463216     Document Type: Article

References (50)

1. R. R. Koenen, "The prowess of platelets in immunity and inflammation, " Thrombosis and Haemostasis, vol. 7, no. 4, pp. 605-612, 2016.
2. J. B. Kral, W. C. Schrottmaier, M. Salzmann, and A. Assinger, "Platelet interaction with innate immune cells, " Transfusion Medicine and Hemotherapy: Offizielles Organ der Deutschen Gesellschaft för Transfusionsmedizin und Immunhamatologie, vol. 43, no. 2, pp. 78-88, 2016.
3. A. Zarbock, K. Singbartl, and K. Ley, "Complete reversal of acid-induced acute lung injury by blocking of plateletneutrophil aggregation, " Journal of Clinical Investigation, vol. 116, no. 12, pp. 3211-3219, 2006.
4. J. Suo, B. Linke, S. Meyer Dos Santos et al., "Neutrophils mediate edema formation but not mechanical allodynia during zymosan-induced inflammation, " Journal of Leukocyte Biology, vol. 96, no. 1, pp. 133-142, 2014.
5. S. Pierre, B. Linke, S. Jing et al., "GPVI and thromboxane receptor on platelets promote proinflammatory macrophage phenotypes during cutaneous inflammation, " Journal of Investigative Dermatology, vol. 137, no. 3, pp. 686-695, 2017.
6. A. Mantovani and C. Garlanda, "Platelet-macrophage partnership in innate immunity and inflammation, " Nature Immunology, vol. 14, no. 8, pp. 768-770, 2013.
7. D. F. Fiorentino, P. Vieira, T. R. Mosmann, M. Howard, K. W. Moore, and A. O'Garra, "IL-10 acts on the antigen-presenting cell to inhibit cytokine production by Th1 cells, " Journal of Immunology, vol. 146, no. 10, pp. 3444-3451, 1991.
8. P. Blanco, A. K. Palucka, V. Pascual, and J. Banchereau, "Dendritic cells and cytokines in human inflammatory and autoimmune diseases, " Cytokine Growth Factor Review, vol. 19, no. 1, pp. 41-52, 2008.
9. P. Chomarat, M. C. Rissoan, J. Banchereau, and P. Miossec, "Interferon gamma inhibits interleukin 10 production by monocytes, " Journal of Experimental Medicine, vol. 177, no. 2, pp. 523-527, 1993.
10. G. Passacquale, P. Vamadevan, L. Pereira, C. Hamid, V. Corrigall, and A. Ferro, "Monocyte-platelet interaction induces a pro-inflammatory phenotype in circulating monocytes, " PloS One, vol. 6, no. 10, article e25595, 2011.
11. F. J. Neumann, M. Gawaz, K. Brand et al., "Induction of cytokine expression in leukocytes by binding of thrombinstimulated platelets, " Circulation, vol. 95, no. 10, pp. 2387-2394, 1997.
12. A. S. Weyrich, M. R. Elstad, R. P. McEver et al., "Activated platelets signal chemokine synthesis by human monocytes, " Journal of Clinical Investigation, vol. 97, no. 6, pp. 1525-1534, 1996.
13. A. S. Weyrich, R. P. McEver, S. M. Prescott, and G. A. Zimmerman, "Monocyte tethering by P-selectin regulates monocyte chemotactic protein-1 and tumor necrosis factoralpha secretion. Signal integration and NF-kappa B translocation, " Journal of Clinical Investigation, vol. 95, no. 5, pp. 2297-2303, 1995.
14. E. N. Boilard, P. A. Larabee, K. Watts et al., "Platelets amplify inflammation in arthritis via collagen-dependent microparticle production, " Science, vol. 29, no. 5965, pp. 580-583, 2010.
15. E. M. Vasina, S. Cauwenberghs, M. A. Feijge, J. W. Heemskerk, C. Weber, and R. R. Koenen, "Microparticles from apoptotic platelets promote resident macrophage differentiation, " Cell Death Discovery, vol. 2, no. 9, p. e211, 2011.
16. S. Sadallah, C. Eken, P. J. Martin, and J. A. Schifferli, "Microparticles (ectosomes) shed by stored human platelets downregulate macrophages and modify the development of dendritic cells, " Journal of Immunology, vol. 186, no. 11, pp. 6543-6552, 2011.
17. B. Laffont, M. Rousseau, A. C. Duchez, C. H. Lee, E. Boilard, and P. Provost, "Platelet microparticles reprogram macrophage gene expression and function, " Thrombosis and Haemostasis, vol. 115, no. 2, pp. 311-323, 2016.
18. F. Soga, N. Katoh, T. Inoue, and S. Kishimoto, "Serotonin activates human monocytes and prevents apoptosis, " The Journal of Investigative Dermatology, vol. 127, no. 8, pp. 1947-1955, 2007.
19. J. Stephen, B. Emerson, K. A. Fox, and I. Dransfield, "The uncoupling of monocyte-platelet interactions from the induction of proinflammatory signaling in monocytes, " Journal of Immunology, vol. 191, no. 11, pp. 5677-5683, 2013.
20. O. Pervushina, "Platelet factor 4/CXCL4 induces phagocytosis and the generation of reactive oxygen metabolites in mononuclear phagocytes independently of Gi protein activation or intracellular calcium transients, " Journal of Immunology, vol. 173, no. 3, pp. 2060-2067, 2004.
21. C. A. Gleissner, I. Shaked, K. M. Little, and K. Ley, "CXC chemokine ligand 4 induces a unique transcriptome in monocytederived macrophages, " Journal of Immunology, vol. 184, no. 9, pp. 4810-4818, 2010.
22. S. Dötting, M. Bender, and B. Nieswandt, "Platelet GPVI: A target for antithrombotic therapy?!, " Trends in Pharmacological Science, vol. 33, no. 11, pp. 583-590, 2012.
23. C. N. Jenne, R. Urrutia, and P. Kubes, "Platelets: bridging hemostasis, inflammation, and immunity, " International Journal of Laboratory Hematology, vol. 35, no. 3, pp. 254-261, 2013.
24. K. Hubertus, M. Mischnik, J. Timmer et al., "Reciprocal regulation of human platelet function by endogenous prostanoids and through multiple prostanoid receptors, " European Journal of Pharmacology, vol. 740, pp. 15-27, 2014.
25. T. Waehre, J. K. Damas, A. Yndestad et al., "Effect of activated platelets on expression of cytokines in peripheral blood mononuclear cells-potential role of prostaglandin E2, " Thrombosis and Haemostasis, vol. 92, no. 6, pp. 1358-1367, 2004.
26. M. Inui, K. Tazawa, Y. Kishi, and T. Takai, "Platelets convert peripheral blood circulating monocytes to regulatory cells via immunoglobulin G and activating-Type Fcgamma receptors, " BMC Immunology, vol. 16, no. 1, p. 20, 2015.
27. T. van der Poll, J. Jansen, M. Levi, H.Ten Cate, J. W.Ten Cate, and S. J. van Deventer, "Regulation of interleukin 10 release by tumor necrosis factor in humans and chimpanzees, " Journal of Experimental Medicine, vol. 180, no. 5, pp. 1985-1988, 1994.
28. S. Gudbrandsdottir, H. C. Hasselbalch, and C. H. Nielsen, "Activated platelets enhance IL-10 secretion and reduce TNF-Alpha secretion by monocytes, " Journal of Immunology, vol. 191, no. 8, pp. 4059-4067, 2013.
29. Y. J. Day, K. H. Chen, T. H. Huang et al., "Preactivated and disaggregated shape-changed platelets protected against acute respiratory distress syndrome complicated by sepsis through inflammation suppression, " Shock, vol. 46, no. 5, pp. 575-586, 2016.
30. G. Strassmann, V. Patil-Koota, F. Finkelman, M. Fong, and T. Kambayashi, "Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages by prostaglandin E2, " Journal of Experimental Medicine, vol. 180, no. 6, pp. 2365-2370, 1994.
31. A. Saha, A. Biswas, S. Srivastav, M. Mukherjee, P. K. Das, and A. Ukil, "Prostaglandin E2 negatively regulates the production of inflammatory cytokines/chemokines and IL-17 in visceral leishmaniasis, " Journal of Immunology, vol. 193, no. 5, pp. 2330-2339, 2014.
32. H. Harizi, "Pivotal role of PGE2 and IL-10 in the cross-regulation of dendritic cell-derived inflammatory mediators, " Cellular and Molecular Immunology, vol. 3, no. 4, pp. 271-277, 2006.
33. H. Hizaki, E. Segi, Y. Sugimoto et al., "Abortive expansion of the cumulus and impaired fertility in mice lacking the prostaglandin E receptor subtype EP(2), " Proceedings of National Academy of Science U S A, vol. 96, no. 18, pp. 10501-10506, 1999.
34. R. Langenbach, S. G. Morham, H. F. Tiano et al., "Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration, " Cell, vol. 83, no. 3, pp. 483-492, 1995.
35. K. Yoshida, H. Oida, T. Kobayashi et al., "Stimulation of bone formation and prevention of bone loss by prostaglandin E EP4 receptor activation, " Proceedings of National Academy of Science U S A, vol. 99, no. 7, pp. 4580-4585, 2002.
36. Y. Niho, H. Niiro, Y. Tanaka, H. Nakashima, and T. Otsuka, "Role of IL-10 in the crossregulation of prostaglandins and cytokines in monocytes, " Acta Haematology, vol. 99, no. 3, pp. 165-170, 1998.
37. E. Vassiliou, H. Jing, and D. Ganea, "Prostaglandin E2 inhibits TNF production in murine bone marrow-derived dendritic cells, " Cellular Immunology, vol. 223, no. 2, pp. 120-132, 2003.
38. H. Harizi and G. Norbert, "Inhibition of IL-6, TNF-Alpha, and cyclooxygenase-2 protein expression by prostaglandin E2-induced IL-10 in bone marrow-derived dendritic cells, " Cellular Immunology, vol. 228, no. 2, pp. 99-109, 2004.
39. C. D. Funk and M. E. Kennedy, "Human platelet/erythroleukemia cell prostaglandin G/H synthase: cDNA cloning, expression, and gene chromosomal assignment, " FASEB Journal, vol. 5, no. 9, pp. 2304-2312, 1991.
40. S. Józefowski, M. Bobek, and J. Marcinkiewicz, "Exogenous but not endogenous prostanoids regulate cytokine secretion from murine bone marrow dendritic cells: EP2, DP, and IP but not EP1, EP3, and FP prostanoid receptors are involved, " International Immunopharmacology, vol. 3, no. 6, pp. 865-878, 2003.
41. H. Harizi, C. Grosset, and N. Gualde, "Prostaglandin E2 modulates dendritic cell function via EP2 and EP4 receptor subtypes, " Journal of Leukocyte Biology, vol. 73, no. 6, pp. 756-763, 2003.
42. C. M. Scull, W. D. Hays, and T. H. Fischer, "Macrophage proinflammatory cytokine secretion is enhanced following interaction with autologous platelets, " Journal of Inflammation, vol. 7, no. 1, p. 53, 2010.
43. Y. Ando, T. Oku, and T. Tsuji, "Platelets attenuate production of cytokines and nitric oxide by macrophages in response to bacterial endotoxin," Platelets, vol. 27, no. 4, pp. 344-350, 2016.
44. G. A. FitzGerald, "The coxibs, selective inhibitors of cyclooxygenase-2," New England Journal of Medicine, vol. 345, no. 6, pp. 433-442, 2001.
45. G. A. FitzGerald, "Coxibs and cardiovascular disease," New England Journal of Medicine, vol. 351, no. 17, pp. 1709-1711, 2004.
46. K. Scholich and G. Geisslinger, "Is mPGES-1 a promising target for pain therapy?" Trends in Pharmacological Science, vol. 27, no. 8, pp. 399-401, 2006.
47. G. M. Kammer, "The adenylate cyclase-cAMP-protein kinase A pathway and regulation of the immune response," Immunology Today, vol. 9, no. 7-8, pp. 222-229, 1988.
48. W. W. Zhong, P. A. Burke, M. E. Drotar, S. R. Chavali, and R. A. Forse, "Effects of prostaglandin E2, cholera toxin and 8-bromo-cyclic AMP on lipopolysaccharide-induced gene expression of cytokines in human macrophages," Immunology, vol. 84, no. 3, pp. 446-452, 1995.
49. H. Cheon, Y. H. Rho, S. J. Choi et al., "Prostaglandin E2 augments IL-10 signaling and function," The Journal of Immunology, vol. 177, no. 2, pp. 1092-1100, 2006.
50. Y. Fujimoto, M. Ozaki, T. Ogino et al., "Involvement of prostaglandin receptors (EPR2-4) in in vivo immunosuppression of PGE2 in rat skin transplant model," International Immunopharmacology, vol. 5, no. 7-8, pp. 1131-1139, 2005.