Different somatic hypermutation levels among antibody subclasses disclosed by a new next-generation sequencing-based antibody repertoire analysis

Frontiers in Immunology

Volumn 8, Issue MAY, 2017, Pages

  Kitaura, Kazutaka ^a   Yamashita, Hiroshi ^a   Ayabe, Hitomi ^a   Shini, Tadasu ^b,c   Matsutani, Takaji ^a   Suzuki, Ryuji ^a,c  

^a Repertoire Genesis Incorporation   (Japan)

^b BITS Company Limited   (Japan)

^c NATIONAL HOSPITAL ORGANIZATION   (Japan)

Author keywords

Antibody; Class switch recombination; Repertoire; Sequencing; Somatic hypermutation

Indexed keywords

ANTIBODY; IMMUNOGLOBULIN A1; IMMUNOGLOBULIN A2; IMMUNOGLOBULIN D ANTIBODY; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN G1 ANTIBODY; IMMUNOGLOBULIN G2 ANTIBODY; IMMUNOGLOBULIN G3 ANTIBODY; IMMUNOGLOBULIN G4 ANTIBODY; IMMUNOGLOBULIN M ANTIBODY; UNCLASSIFIED DRUG;

AMINO ACID COMPOSITION; AMINO ACID SEQUENCE; ANTIBODY REPERTOIRE ANALYSIS; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENETIC VARIABILITY; HUMAN; MALE; MEDICAL PROCEDURES; NEXT GENERATION SEQUENCING; POLYMERASE CHAIN REACTION; RNA EXTRACTION; SOMATIC HYPERMUTATION;

EID: 85020011943     PISSN: None     EISSN: 16643224     Source Type: Journal    
DOI: 10.3389/fimmu.2017.00389     Document Type: Article

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