Chicken egg yolk antibodies (IgY) for prophylaxis and treatment of rotavirus diarrhea in human and animal neonates: A concise review

Korean Journal for Food Science of Animal Resources

Volumn 37, Issue 1, 2017, Pages 1-9

  Thu, Hlaing Myat ^a   Myat, Theingi Win ^a   Win, Mo Mo ^a   Thant, Kyaw Zin ^a   Rahman, Shofiqur ^b   Umeda, Kouji ^b   Van Nguyen, Sa ^b   Icatlo, Faustino C ^b   Higo Moriguchi, Kyoko ^c   Taniguchi, Koki ^c   Tsuji, Takao ^c   Oguma, Keiji ^d   Kim, Sang Jong ^e   Bae, Hyun Suk ^e   Choi, Hyuk Joon ^f  

^a Department of Medical Research ^*  (Myanmar)

^b Immunology Research Institute in Gifu   (Japan)

^c FUJITA HEALTH UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^d OKAYAMA UNIVERSITY   (Japan)

^e Lotte RandD Center   (South Korea)

^f BK Bio   (South Korea)

Author keywords

Diarrhea disease; IgY; Neonates; Oral passive immunotherapy; Rotavirus

Indexed keywords

EID: 85020007672     PISSN: 12258563     EISSN: 2234246X     Source Type: Journal    
DOI: 10.5851/kosfa.2017.37.1.1     Document Type: Review

References (38)

1. Arimitsu, H., Sasaki, K., Kohda, T., Shimizu, T., and Tsuji, T. (2014) Evaluation of Shiga toxin 2e-specific chicken egg yolk immunoglobulin: Production and neutralization activity. Microbiol. Immunol. 58, 643-648.
2. Barnes, G. L., Hewson, P. H., Mclellan, J. A., Doyle, L. W., Knoches, A. M. L., and Kitchen,W. H. (1982) A randomised trial of oral gammaglobulin in low-birth-weight infants infected with rotavirus. The Lancet. 319, 1371-1373.
3. Bäumler, A. J. and Sperandio, V. (2016) Interactions between the microbiota and pathogenic bacteria in the gut. Nature 535, 85-93.
4. Bhavnani, D., Goldstick, J. E., Cevallos, W., Trueba, G., and Eisenberg, J. N. S. (2012) Synergistic effects between rotavirus and coinfecting pathogens on diarrheal disease: Evidence from a community-based study in Northwestern Ecuador. Am. J. Epidemiol. 176, 387-395.
5. Dai, Y. C., Wang, Y. Y., Zhang, X. F., Tan, M., Xia, M., Wu, X. B., Jiang, X., and Nie, J. (2012) Evaluation of anti-norovirus IgY from egg yolk of chickens immunized with norovirus P particles. J. Virol. Methods 186, 126-131.
6. Dhama, K., Chauhan, R. S., Mahendran, M., and Malik, S. V. S. (2009) Rotavirus diarrhea in bovines and other domesticated animals. Vet. Res. Comm. 33, 1-23.
7. Diraviyam, T., Zhao, B., Wang, Y., Schade, R., Michael A., and Zhang, X. (2014) Effect of chicken egg yolk antibodies (IgY) against diarrhea in domesticated animals: A systematic review and meta-analysis. PLoS ONE 9, e97716.
8. Gujral, N., Löbenberg, R., Suresh, M., and Sunwoo, H. (2012) In vitro and in vivo binding activity of chicken egg yolk immunoglobulin Y (IgY) against gliadin in food matrix. J. Agric. Food Chem. 60, 3166-3172.
9. Hatta, H., Tsuda, K., Akachi, S., Kim, M., Yamamoto, T., and Ebina, T. (1993) Oral passive immunization effect of antihuman rotavirus IgY and its behavior against proteolytic enzymes. Biosci. Biotechnol. Biochem. 57, 1077-1081.
10. Hirai, K., Arimitsu, H., Umeda, K., Yokota, K., Shen, L., Ayada, K., Kodama, Y., Tsuji, T., Hirai, Y., and Oguma, K. (2010) Passive oral immunization by egg yolk immunoglobulin (IgY) to Vibrio cholerae effectively prevents cholera. Acta Med. Okayama. 64, 163-170.
11. Hirose, M., Ando, T., Shofiqur R., Umeda K., Kodama Y., Nguyen S. V., Goto, T., Shimada, M., and Nagaoka, S. (2013) Anti-obesity activity of hen egg anti-lipase immunoglobulin yolk, a novel pancreatic lipase inhibitor. Nutr. Metab. (Lond). 10, 70.
12. Hlaing, M. T., Theingi, W. M., Mo Mo, W., Kyaw, Z. T., Rahman, S., Umeda, K., Nguyen, V. S., Icatlo, F. C., Jr., Moriguchi, K. H., Taniguchi, K., Tsuji. T., and Oguma, K. (2015). Immunoglobulin Y-fortified infant milk formula as adjunct to treatment of diarrhea among rotavirus-infected hospitalized children in Myanmar: A randomized, double-blind, placebo-controlled trial. Unpublished data.
13. Ibrahim, El-S. M., Rahman, A. K. M. S., Isoda, R., Umeda, K., van Sa, N., and Kodama Y. (2008) In vitro and in vivo effectiveness of egg yolk antibody against Candida albicans (anti- CA IgY). Vaccine 26, 2073-2080.
14. Ikemori, Y, Peralta, R.C., Kuroki, M., Yokoyama, H., and Kodama Y. (1993) Avidity of chicken yolk antibodies to enterotoxigenic Escherichia coli fimbriae. Poult Sci. 72, 2361-2365.
15. Ikemori, Y., Ohta, M., Umeda, K., Peralta, R. C., Kuroki, M., Yokoyama, H., and Kodama, Y. (1996) Passage of chicken egg yolk antibody treated with hydroxypropyl methylcellulose phthalate in the gastrointestinal tract of calves. J. Vet. Med. Sci. 58, 365-367.
16. Kollberg, H. (2015) Avian antibodies (IgY) to fight antibiotic resistance. Clin. Microbiol. 4, 2. 1000194.
17. Lee, C. H., Lee, Y. C., Liang, M. H., Leu, S. J., Lin, L. T., Chiang, J. R., and Yang, Y. Y. (2015) Antibodies against venom of the snake Deinagkistrodon acutus. Appl. Environ. Microbiol. 82, 71-80.
18. Lee, K. E., Han, B. K., Han, J. Y., Hong, J. Y., Kim, M. N., Heo, W. I., Sohn, M. H., Kim, K. W., and Kim, K. E. (2014) Production of egg yolk antibodies specific to house dust mite proteins. Yonsei Med. J. 55, 999-1004.
19. Li, X. Y., Jin, L. J., Uzonna, J. E., Li, S. Y., Liu, J. J., Li, H. Q., Lu, Y. N., Zhen, Y. H., and Xu, Y. P. (2009) Chitosan-alginate microcapsules for oral delivery of egg yolk immunoglobulin (IgY): In vivo evaluation in a pig model of enteric colibacillosis. Vet. Immunol. Immunopathol.129, 132-136.
20. Müller, S., Schubert, A., Zajac, J., Dyck, T., and Oelkrug, C. (2015) IgY antibodies in human nutrition for disease prevention. Nutr. J. 14, 109.
21. Neri, P., Tokoro, S., Sugiyama, T., Umeda, K., Shimizu, T., Tsuji, T., Kodama Y., and Mori, H. (2012) Recombinant Shiga toxin B subunit can induce neutralizing immunoglobulin Y antibody. Biol. Pharm. Bull. 35, 917-923.
22. Nilsson, E., Larsson, A., Olesen, H.V., Wejaker, P. E., and Kollberg, H. (2008) Good effect of IgY against Pseudomonas aeruginosa infections in cystic fibrosis patients. Pediatr Pulmonol. 43, 892-899.
23. Nguyen, H. H., Tumpey, T. M., Park, H. J., Byun, Y. H., Tran, L. D., Nguyen, V. D., Kilgore, P. E., Czerkinsky, C., Katz, J. M., Seong, B. L., Song, J. M., Kim, Y. B., Do, H. T., Nguyen, T., and Nguyen, C. V. (2010) Prophylactic and therapeutic efficacy of avian antibodies against influenza virus H5N1 and H1N1 in mice. PLoS ONE. 5, e10152.
24. Nguyen, S. V., Icatlo, Jr. F. C., Nakano, T., Isogai, E., Hirose, K., Mizugai, H., Kobayashi-Sakamoto, M., Isogai, H., and Chiba, I. (2011) Anti cell-associated glucosyltransferase immunoglobulin Y suppression of salivary mutans streptococci in healthy young adults. J. Ame. Dent. Assoc. 142, 943-949.
25. Pammi, M. and Haque, K. N. (2011) Oral immunoglobulin for the treatment of rotavirus diarrhea in low birth weight infants. Cochrane Database Syst. Rev. 5.
26. Parr, R. D., Storey, S. M., Mitchell, D. M., McIntosh, A. L., Zhou, M., Mir, K. D., and Ball, J. M. (2006) The rotavirus enterotoxin NSP4 directly interacts with the caveolar structural protein caveolin-1. J. Virol. 80, 2842-2854.
27. Raffatellu, M. and Baumler, A. J. (2010) Salmonella's iron armor for battling the host and its microbiota. Gut Microbes. 1, 70-72.
28. Rahman, S., Higo-Moriguchi, K., Htun, K. W., Taniguchi, K., Icatlo, F. C., Jr., Tsuji, T., Kodama, Y., van Nguyen, S., Umeda, K., Oo, H. N., Myint, Y. Y., Htut, T., Myint, S. S., Thura, K., Thu, H. M., Fatmawati, N. N., and Oguma, K. (2012) Randomized placebo-controlled clinical trial of immunoglobulin Y as adjunct to standard supportive therapy for rotavirus-associated diarrhea among pediatric patients. Vaccine 30, 4661-4669.
29. Rahman, S., Nguyen, S., Icatlo, F., Umeda, K., and Kodama, Y. (2013a) Oral passive IgY-based immunotherapeutics: A novel solution for prevention and treatment of alimentary tract diseases. Hum. Vaccines Immunotherapeutics 9, 1039-1048.
30. Rahman, S., Umeda, K., Icatlo, Jr. F. C., Lee, K. W., Kim, S. H., Choi, H. J., Han, B. K., Park, Y. S., and Sa, N. V. (2013b) In vitro cytoprotective effect of infant milk formula fortified with human rotavirus-specific hyperimmune yolk immunoglobulins (IgY). Food Sci. Biotechnol. 22, 1699-1705.
31. Robert, F. R. (2004) Pathogenesis of intestinal and systemic rotavirus infection. J. Virol. 78, 10213-10220.
32. Sarker, S. A., Casswall, T. H., Juneja, L. R., Hoq, E., Hossain, I., Fuchs, G. J., and Hammarström L. (2001) Randomized, placebo- controlled, clinical trial of hyperimmunized chicken egg yolk immunoglobulin in children with rotavirus diarrhea. J. Pediatr. Gastroenterol. Nutr. 32, 19-25.
33. Selvan, K., Sentila, R., and Michael, A. (2012) Generation and characterization of chicken egg yolk antibodies against Propionibacterium acnes for the prevention of acne Vulgaris. Ind. J. Dermatol. 57, 15-19.
34. Shin, J. H., Yang, M., Nam, S.W., Kim, J. T., Myung, N. H., Bang, W.G., and Roe, I. H. (2002) Use of egg yolk-derived immunoglobulin as an alternative to antibiotic treatment for control of Helicobacter pylori infection. Clin. Diagn. Lab. Immunol. 9, 1061-1066.
35. Suzuki, H., Nomura, S., Masaoka, T., Goshima, H., Kamata, N., Kodama Y, Ishii, H., Kitajima, M., Nomoto, K., and Hibi, T. (2004) Effect of dietary anti-Helicobacter pylori-urease immunoglobulin Y on Helicobacter pylori infection. Aliment Pharmacol. Therapeut. 20, 185-192.
36. Vega, C., Bok, M., Saif, L., Fernandez, F., and Parreño, V. (2015) Egg yolk IgY antibodies: A therapeutic intervention against group A rotavirus in calves. Res. Vet. Sci. 103, 1-10.
37. Yokoyama, H., Peralta, R. C., Sendo, S., Ikemori, Y., and Kodama, Y. (1993) Detection of passage and absorption of chicken egg yolk immunoglobulins in the gastrointestinal tract of pigs by use of enzyme-linked immunosorbent assay and fluorescent antibody testing. Am. J. Vet. Res. 54, 867-872.
38. Yokoyama, K., Sugano, N., Shimada, T., Shofiqur, R. A., Ibrahim, El-S. M., Isoda, R., Umeda, K., van Sa, N., Kodama, Y., and Ito, K. (2007) Effects of egg yolk antibody against Porphyromonas gingivalis gingipains in periodontitis patients. J. Oral Sci. 49, 201-206.