-
1
-
-
69949186250
-
Screening for epidermal growth factor receptor mutations in lung cancer
-
Rosell R, Moran T, Queralt C, Porta R, Cardenal F, Camps C, et al. Screening for epidermal growth factor receptor mutations in lung cancer. N Engl J Med 2009;361:958–67.
-
(2009)
N Engl J Med
, vol.361
, pp. 958-967
-
-
Rosell, R.1
Moran, T.2
Queralt, C.3
Porta, R.4
Cardenal, F.5
Camps, C.6
-
2
-
-
84861083983
-
Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: A phase 1 dose-escalation trial
-
Falchook GS, Long GV, Kurzrock R, Kim KB, Arkenau TH, Brown MP, et al. Dabrafenib in patients with melanoma, untreated brain metastases, and other solid tumours: A phase 1 dose-escalation trial. Lancet 2012;379: 1893–901.
-
(2012)
Lancet
, vol.379
, pp. 1893-1901
-
-
Falchook, G.S.1
Long, G.V.2
Kurzrock, R.3
Kim, K.B.4
Arkenau, T.H.5
Brown, M.P.6
-
3
-
-
84883680951
-
Panitumumab-folfox4 treatment and ras mutations in colorectal cancer
-
Douillard JY, Oliner KS, Siena S, Tabernero J, Burkes R, Barugel M, et al. Panitumumab-FOLFOX4 treatment and RAS mutations in colorectal cancer. N Engl J Med 2013;369:1023–34.
-
(2013)
N Engl J Med
, vol.369
, pp. 1023-1034
-
-
Douillard, J.Y.1
Oliner, K.S.2
Siena, S.3
Tabernero, J.4
Burkes, R.5
Barugel, M.6
-
4
-
-
84863338519
-
PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations
-
Janku F, Wheler JJ, Westin SN, Moulder SL, Naing A, Tsimberidou AM, et al. PI3K/AKT/mTOR inhibitors in patients with breast and gynecologic malignancies harboring PIK3CA mutations. J Clin Oncol 2012;30:777–82.
-
(2012)
J Clin Oncol
, vol.30
, pp. 777-782
-
-
Janku, F.1
Wheler, J.J.2
Westin, S.N.3
Moulder, S.L.4
Naing, A.5
Tsimberidou, A.M.6
-
5
-
-
84963976837
-
Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, kras codon 12/13 wild-type, her2-positive metastatic colorectal cancer (heracles): a proof-of-concept, multicentre, open-label, phase 2 trial
-
Sartore-Bianchi A, Trusolino L, Martino C, Bencardino K, Lonardi S, Bergamo F, et al. Dual-targeted therapy with trastuzumab and lapatinib in treatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): A proof-of-concept, multicentre, open-label, phase 2 trial. Lancet Oncol 2016;17:738–46.
-
(2016)
Lancet Oncol
, vol.17
, pp. 738-746
-
-
Sartore-Bianchi, A.1
Trusolino, L.2
Martino, C.3
Bencardino, K.4
Lonardi, S.5
Bergamo, F.6
-
6
-
-
84910088551
-
Outcomes of patients with advanced cancer and kras mutations in phase i clinical trials
-
Said R, Ye Y, Falchook GS, Janku F, Naing A, Zinner R, et al. Outcomes of patients with advanced cancer and KRAS mutations in phase I clinical trials. Oncotarget 2014;5:8937–46.
-
(2014)
Oncotarget
, vol.5
, pp. 8937-8946
-
-
Said, R.1
Ye, Y.2
Falchook, G.S.3
Janku, F.4
Naing, A.5
Zinner, R.6
-
7
-
-
84863116014
-
Effect of kras oncogene substitutions on protein behavior: Implications for signaling and clinical outcome
-
Ihle NT, Byers LA, Kim ES, Saintigny P, Lee JJ, Blumenschein GR, et al. Effect of KRAS oncogene substitutions on protein behavior: implications for signaling and clinical outcome. J Natl Cancer Inst 2012;104:228–39.
-
(2012)
J Natl Cancer Inst
, vol.104
, pp. 228-239
-
-
Ihle, N.T.1
Byers, L.A.2
Kim, E.S.3
Saintigny, P.4
Lee, J.J.5
Blumenschein, G.R.6
-
8
-
-
34047248571
-
Oncogenic activation of the Ras/raf signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies
-
Benvenuti S, Sartore-Bianchi A, Di Nicolantonio F, Zanon C, Moroni M, Veronese S, et al. Oncogenic activation of the RAS/RAF signaling pathway impairs the response of metastatic colorectal cancers to anti-epidermal growth factor receptor antibody therapies. Cancer Res 2007;67:2643–8.
-
(2007)
Cancer Res
, vol.67
, pp. 2643-2648
-
-
Benvenuti, S.1
Sartore-Bianchi, A.2
Di Nicolantonio, F.3
Zanon, C.4
Moroni, M.5
Veronese, S.6
-
9
-
-
85024394912
-
Profile-related evidence to determine individualized cancer therapy (predict): Preliminary results of the personalized phase i clinical trials program at md anderson cancer center
-
Orlando, FL: AACR
-
Tsimberidou AM, Hong DS, Wheler JJ, Fu S, Piha-Paul S, Naing A, et al. Profile-related evidence to determine individualized cancer therapy (PREDICT): Preliminary results of the Personalized Phase I Clinical Trials program at MD Anderson Cancer Center. In: Proceedings of the 102nd Annual Meeting of the American Association for Cancer Research; 2011 Apr 2–6; Orlando, FL: AACR; 2011. Abstract nr 1287.
-
(2011)
Proceedings of The 102nd Annual Meeting of The American Association for Cancer Research; 2011 Apr 2–6
-
-
Tsimberidou, A.M.1
Hong, D.S.2
Wheler, J.J.3
Fu, S.4
Piha-Paul, S.5
Naing, A.6
-
10
-
-
84903512238
-
Braf v600e mutations in urine and plasma cell-free dna from patients with erdheim-chester disease
-
Janku F, Vibat CR, Kosco K, Holley VR, Cabrilo G, Meric-Bernstam F, et al. BRAF V600E mutations in urine and plasma cell-free DNA from patients with Erdheim-Chester disease. Oncotarget 2014;5:3607–10.
-
(2014)
Oncotarget
, vol.5
, pp. 3607-3610
-
-
Janku, F.1
Vibat, C.R.2
Kosco, K.3
Holley, V.R.4
Cabrilo, G.5
Meric-Bernstam, F.6
-
11
-
-
84855558810
-
Personalized medicine in a phase i clinical trials program: The m. d. anderson cancer center initiative
-
Tsimberidou AM, Iskander NG, Hong DS, Wheler JJ, Fu S, Piha-Paul SA, et al. Personalized medicine in a phase I clinical trials program: The M. D. Anderson Cancer Center Initiative. J Clin Oncol 2011;29:abstr CRA2500.
-
(2011)
J Clin Oncol
, vol.29
-
-
Tsimberidou, A.M.1
Iskander, N.G.2
Hong, D.S.3
Wheler, J.J.4
Fu, S.5
Piha-Paul, S.A.6
-
12
-
-
79951834210
-
Pik3ca mutations may be discordant between primary and corresponding metastatic disease in breast cancer
-
Dupont Jensen J, Laenkholm AV, Knoop A, Ewertz M, Bandaru R, Liu W, et al. PIK3CA mutations may be discordant between primary and corresponding metastatic disease in breast cancer. Clin Cancer Res 2011; 17:667–77.
-
(2011)
Clin Cancer Res
, vol.17
, pp. 667-677
-
-
Dupont Jensen, J.1
Laenkholm, A.V.2
Knoop, A.3
Ewertz, M.4
Bandaru, R.5
Liu, W.6
-
13
-
-
84863393080
-
Intratumor heterogeneity and branched evolution revealed by multi-region sequencing
-
Gerlinger M, Rowan AJ, Horswell S, Larkin J, Endesfelder D, Gronroos E, et al. Intratumor heterogeneity and branched evolution revealed by multi-region sequencing. N Engl J Med 2012;366:883–92.
-
(2012)
N Engl J Med
, vol.366
, pp. 883-892
-
-
Gerlinger, M.1
Rowan, A.J.2
Horswell, S.3
Larkin, J.4
Endesfelder, D.5
Gronroos, E.6
-
14
-
-
79958728268
-
Pi3k pathway mutations and pten levels in primary and metastatic breast cancer
-
Gonzalez-Angulo AM, Ferrer-Lozano J, Stemke-Hale K, Sahin A, Liu S, Barrera JA, et al. PI3K pathway mutations and PTEN levels in primary and metastatic breast cancer. Mol Cancer Ther 2011;10:1093–101.
-
(2011)
Mol Cancer Ther
, vol.10
, pp. 1093-1101
-
-
Gonzalez-Angulo, A.M.1
Ferrer-Lozano, J.2
Stemke-Hale, K.3
Sahin, A.4
Liu, S.5
Barrera, J.A.6
-
15
-
-
79953118839
-
Genotypic and histological evolution of lung cancers acquiring resistance to egfr inhibitors
-
Sequist LV, Waltman BA, Dias-Santagata D, Digumarthy S, Turke AB, Fidias P, et al. Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors. Sci Transl Med 2011;3:75ra26.
-
(2011)
Sci Transl Med
, vol.3
, pp. 75ra26
-
-
Sequist, L.V.1
Waltman, B.A.2
Dias-Santagata, D.3
Digumarthy, S.4
Turke, A.B.5
Fidias, P.6
-
16
-
-
84949535312
-
Testing for oncogenic molecular aberrations in cell-free dna-based liquid biopsies in the clinic: Are we there yet?
-
Polivka J Jr, Pesta M, Janku F. Testing for oncogenic molecular aberrations in cell-free DNA-based liquid biopsies in the clinic: Are we there yet? Expert Rev Mol Diagn 2015;15:1631–44.
-
(2015)
Expert Rev Mol Diagn
, vol.15
, pp. 1631-1644
-
-
Polivka, J.1
Pesta, M.2
Janku, F.3
-
17
-
-
84863000299
-
The molecular evolution of acquired resistance to targeted egfr blockade in colorectal cancers
-
Diaz LA Jr, Williams RT, Wu J, Kinde I, Hecht JR, Berlin J, et al. The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers. Nature 2012;486:537–40.
-
(2012)
Nature
, vol.486
, pp. 537-540
-
-
Diaz La1
Williams, R.T.2
Wu, J.3
Kinde, I.4
Hecht, J.R.5
Berlin, J.6
-
18
-
-
84926431987
-
Characterizing the patterns of clonal selection in circulating tumor dna from patients with colorectal cancer refractory to anti-egfr treatment
-
Morelli MP, Overman MJ, Dasari A, Kazmi SM, Mazard T, Vilar E, et al. Characterizing the patterns of clonal selection in circulating tumor DNA from patients with colorectal cancer refractory to anti-EGFR treatment. Ann Oncol 2015;26:731–6.
-
(2015)
Ann Oncol
, vol.26
, pp. 731-736
-
-
Morelli, M.P.1
Overman, M.J.2
Dasari, A.3
Kazmi, S.M.4
Mazard, T.5
Vilar, E.6
-
19
-
-
84862999938
-
Emergence of kras mutations and acquired resistance to anti-egfr therapy in colorectal cancer
-
Misale S, Yaeger R, Hobor S, Scala E, Janakiraman M, Liska D, et al. Emergence of KRAS mutations and acquired resistance to anti-EGFR therapy in colorectal cancer. Nature 2012;486:532–6.
-
(2012)
Nature
, vol.486
, pp. 532-536
-
-
Misale, S.1
Yaeger, R.2
Hobor, S.3
Scala, E.4
Janakiraman, M.5
Liska, D.6
-
20
-
-
84936748494
-
Clonal evolution and resistance to egfr blockade in the blood of colorectal cancer patients
-
Siravegna G, Mussolin B, Buscarino M, Corti G, Cassingena A, Crisafulli G, et al. Clonal evolution and resistance to EGFR blockade in the blood of colorectal cancer patients. Nat Med 2015;21:795–801.
-
(2015)
Nat Med
, vol.21
, pp. 795-801
-
-
Siravegna, G.1
Mussolin, B.2
Buscarino, M.3
Corti, G.4
Cassingena, A.5
Crisafulli, G.6
-
21
-
-
84922372527
-
Prospective blinded study of brafv600e mutation detection in cell-free dna of patients with systemic histiocytic disorders
-
Hyman DM, Diamond EL, Vibat CR, Hassaine L, Poole JC, Patel M, et al. Prospective blinded study of BRAFV600E mutation detection in cell-free DNA of patients with systemic histiocytic disorders. Cancer Discov 2015;5:64–71.
-
(2015)
Cancer Discov
, vol.5
, pp. 64-71
-
-
Hyman, D.M.1
Diamond, E.L.2
Vibat, C.R.3
Hassaine, L.4
Poole, J.C.5
Patel, M.6
-
22
-
-
84991067919
-
A highly sensitive and quantitative test platform for detection of nsclc egfr mutations in urine and plasma
-
Reckamp KL, Melnikova VO, Karlovich C, Sequist LV, Camidge DR, Wakelee H, et al. A highly sensitive and quantitative test platform for detection of NSCLC EGFR mutations in urine and plasma. J Thorac Oncol 2016;11:1690–700.
-
(2016)
J Thorac Oncol
, vol.11
, pp. 1690-1700
-
-
Reckamp, K.L.1
Melnikova, V.O.2
Karlovich, C.3
Sequist, L.V.4
Camidge, D.R.5
Wakelee, H.6
-
23
-
-
57849117384
-
New response evaluation criteria in solid tumours: Revised recist guideline (version 1.1)
-
Eisenhauer EA, Therasse P, Bogaerts J, Schwartz LH, Sargent D, Ford R, et al. New response evaluation criteria in solid tumours: Revised RECIST guideline (version 1.1). Eur J Cancer 2009;45:228–47.
-
(2009)
Eur J Cancer
, vol.45
, pp. 228-247
-
-
Eisenhauer, E.A.1
Therasse, P.2
Bogaerts, J.3
Schwartz, L.H.4
Sargent, D.5
Ford, R.6
-
24
-
-
84930025659
-
Actionable mutations in plasma cell-free dna in patients with advanced cancers referred for experimental targeted therapies
-
Janku F, Angenendt P, Tsimberidou AM, Fu S, Naing A, Falchook GS, et al. Actionable mutations in plasma cell-free DNA in patients with advanced cancers referred for experimental targeted therapies. Oncotarget 2015;6: 12809–21.
-
(2015)
Oncotarget
, vol.6
, pp. 12809-12821
-
-
Janku, F.1
Angenendt, P.2
Tsimberidou, A.M.3
Fu, S.4
Naing, A.5
Falchook, G.S.6
-
25
-
-
84862537727
-
Detection of tumor pik3ca status in metastatic breast cancer using peripheral blood
-
Higgins MJ, Jelovac D, Barnathan E, Blair B, Slater S, Powers P, et al. Detection of tumor PIK3CA status in metastatic breast cancer using peripheral blood. Clin Cancer Res 2012;18:3462–9.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 3462-3469
-
-
Higgins, M.J.1
Jelovac, D.2
Barnathan, E.3
Blair, B.4
Slater, S.5
Powers, P.6
-
26
-
-
84938055998
-
Analysis of circulating dna and protein biomarkers to predict the clinical activity of regorafenib and assess prognosis in patients with metastatic colorectal cancer: A retrospective, exploratory analysis of the correct trial
-
Tabernero J, Lenz HJ, Siena S, Sobrero A, Falcone A, Ychou M, et al. Analysis of circulating DNA and protein biomarkers to predict the clinical activity of regorafenib and assess prognosis in patients with metastatic colorectal cancer: A retrospective, exploratory analysis of the CORRECT trial. Lancet Oncol 2015;16:937–48.
-
(2015)
Lancet Oncol
, vol.16
, pp. 937-948
-
-
Tabernero, J.1
Lenz, H.J.2
Siena, S.3
Sobrero, A.4
Falcone, A.5
Ychou, M.6
-
27
-
-
84898476658
-
Clinical validation of the detection of kras and braf mutations from circulating tumor Dna
-
Thierry AR, Mouliere F, El Messaoudi S, Mollevi C, Lopez-Crapez E, Rolet F, et al. Clinical validation of the detection of KRAS and BRAF mutations from circulating tumor DNA. Nat Med 2014;20:430–5.
-
(2014)
Nat Med
, vol.20
, pp. 430-435
-
-
Thierry, A.R.1
Mouliere, F.2
El Messaoudi, S.3
Mollevi, C.4
Lopez-Crapez, E.5
Rolet, F.6
-
28
-
-
84975461688
-
Prospective validation of rapid plasma genotyping for the detection of egfr and kras mutations in advanced lung cancer
-
Sacher AG, Paweletz C, Dahlberg SE, Alden RS, O'Connell A, Feeney N, et al. Prospective validation of rapid plasma genotyping for the detection of EGFR and KRAS mutations in advanced lung cancer. JAMA Oncol 2016;2:1014–22.
-
(2016)
JAMA Oncol
, vol.2
, pp. 1014-1022
-
-
Sacher, A.G.1
Paweletz, C.2
Dahlberg, S.E.3
Alden, R.S.4
O'Connell, A.5
Feeney, N.6
-
29
-
-
84940095522
-
Serial next-generation sequencing of circulating cell-free dna evaluating tumor clone response to molecularly targeted drug administration
-
Frenel JS, Carreira S, Goodall J, Roda D, Perez-Lopez R, Tunariu N, et al. Serial next-generation sequencing of circulating cell-free DNA evaluating tumor clone response to molecularly targeted drug administration. Clin Cancer Res 2015;21:4586–96.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 4586-4596
-
-
Frenel, J.S.1
Carreira, S.2
Goodall, J.3
Roda, D.4
Perez-Lopez, R.5
Tunariu, N.6
-
30
-
-
84899837889
-
Concordance of genomic alterations between primary and recurrent breast cancer
-
Meric-Bernstam F, Frampton GM, Ferrer-Lozano J, Yelensky R, Perez-Fidalgo JA, Wang Y, et al. Concordance of genomic alterations between primary and recurrent breast cancer. Mol Cancer Ther 2014;13:1382–9.
-
(2014)
Mol Cancer Ther
, vol.13
, pp. 1382-1389
-
-
Meric-Bernstam, F.1
Frampton, G.M.2
Ferrer-Lozano, J.3
Yelensky, R.4
Perez-Fidalgo, J.A.5
Wang, Y.6
-
31
-
-
84971516426
-
Braf mutation testing in cell-free dna from the plasma of patients with advanced cancers using a rapid, automated molecular diagnostics system
-
Janku F, Huang HJ, Claes B, Falchook GS, Fu S, Hong D, et al. BRAF mutation testing in cell-free DNA from the plasma of patients with advanced cancers using a rapid, automated molecular diagnostics system. Mol Cancer Ther 2016;15:1397–404.
-
(2016)
Mol Cancer Ther
, vol.15
, pp. 1397-1404
-
-
Janku, F.1
Huang, H.J.2
Claes, B.3
Falchook, G.S.4
Fu, S.5
Hong, D.6
-
32
-
-
84873207633
-
The prognostic value of kras mutated plasma dna in advanced non-small cell lung cancer
-
Nygaard AD, Garm Spindler KL, Pallisgaard N, Andersen RF, Jakobsen A. The prognostic value of KRAS mutated plasma DNA in advanced non-small cell lung cancer. Lung Cancer 2013;79:312–7.
-
(2013)
Lung Cancer
, vol.79
, pp. 312-317
-
-
Nygaard, A.D.1
Garm Spindler, K.L.2
Pallisgaard, N.3
Andersen, R.F.4
Jakobsen, A.5
-
33
-
-
84857076207
-
Quantitative cell-free dna, kras, and braf mutations in plasma from patients with metastatic colorectal cancer during treatment with cetuximab and irinotecan
-
Spindler KL, Pallisgaard N, Vogelius I, Jakobsen A. Quantitative cell-free DNA, KRAS, and BRAF mutations in plasma from patients with metastatic colorectal cancer during treatment with cetuximab and irinotecan. Clin Cancer Res 2012;18:1177–85.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 1177-1185
-
-
Spindler, K.L.1
Pallisgaard, N.2
Vogelius, I.3
Jakobsen, A.4
-
34
-
-
84958978046
-
Correlation of braf mutation status in circulating-free dna and tumor and association with clinical outcome across four brafi and meki clinical trials
-
Santiago-Walker A, Gagnon R, Mazumdar J, Casey M, Long GV, Schadendorf D, et al. Correlation of BRAF mutation status in circulating-free DNA and tumor and association with clinical outcome across four BRAFi and MEKi clinical trials. Clin Cancer Res 2016;22:567–74.
-
(2016)
Clin Cancer Res
, vol.22
, pp. 567-574
-
-
Santiago-Walker, A.1
Gagnon, R.2
Mazumdar, J.3
Casey, M.4
Long, G.V.5
Schadendorf, D.6
-
35
-
-
84965092386
-
Association of egfr l858r mutation in circulating free dna with survival in the eurtac trial
-
Karachaliou N, Mayo-de las Casas C, Queralt C, de Aguirre I, Melloni B, Cardenal F, et al. Association of EGFR L858R mutation in circulating free DNA with survival in the EURTAC trial. JAMA Oncol 2015;1:149–57.
-
(2015)
JAMA Oncol
, vol.1
, pp. 149-157
-
-
Karachaliou, N.1
Mayo-De Las Casas, C.2
Queralt, C.3
De Aguirre, I.4
Melloni, B.5
Cardenal, F.6
-
36
-
-
84896371874
-
Detection of circulating tumor dna in early- and late-stage human malignancies
-
Bettegowda C, Sausen M, Leary RJ, Kinde I, Wang Y, Agrawal N, et al. Detection of circulating tumor DNA in early- and late-stage human malignancies. Sci Transl Med 2014;6:224ra24.
-
(2014)
Sci Transl Med
, vol.6
, pp. 224ra24
-
-
Bettegowda, C.1
Sausen, M.2
Leary, R.J.3
Kinde, I.4
Wang, Y.5
Agrawal, N.6
-
37
-
-
84875520648
-
Analysis of circulating tumor dna to monitor metastatic breast cancer
-
Dawson SJ, Tsui DW, Murtaza M, Biggs H, Rueda OM, Chin SF, et al. Analysis of circulating tumor DNA to monitor metastatic breast cancer. N Engl J Med 2013;368:1199–209.
-
(2013)
N Engl J Med
, vol.368
, pp. 1199-1209
-
-
Dawson, S.J.1
Tsui, D.W.2
Murtaza, M.3
Biggs, H.4
Rueda, O.M.5
Chin, S.F.6
-
38
-
-
84861746437
-
Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma Dna
-
Forshew T, Murtaza M, Parkinson C, Gale D, Tsui DW, Kaper F, et al. Noninvasive identification and monitoring of cancer mutations by targeted deep sequencing of plasma DNA. Sci Transl Med 2012;4:136ra68.
-
(2012)
Sci Transl Med
, vol.4
, pp. 136ra68
-
-
Forshew, T.1
Murtaza, M.2
Parkinson, C.3
Gale, D.4
Tsui, D.W.5
Kaper, F.6
-
39
-
-
84877579861
-
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma Dna
-
Murtaza M, Dawson SJ, Tsui DW, Gale D, Forshew T, Piskorz AM, et al. Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA. Nature 2013;497:108–12.
-
(2013)
Nature
, vol.497
, pp. 108-112
-
-
Murtaza, M.1
Dawson, S.J.2
Tsui, D.W.3
Gale, D.4
Forshew, T.5
Piskorz, A.M.6
-
40
-
-
84896539307
-
Noninvasive detection of response and resistance in egfr-mutant lung cancer using quantitative next-generation genotyping of cell-free plasma Dna
-
Oxnard GR, Paweletz CP, Kuang Y, Mach SL, O'Connell A, Messineo MM, et al. Noninvasive detection of response and resistance in EGFR-mutant lung cancer using quantitative next-generation genotyping of cell-free plasma DNA. Clin Cancer Res 2014;20:1698–705.
-
(2014)
Clin Cancer Res
, vol.20
, pp. 1698-1705
-
-
Oxnard, G.R.1
Paweletz, C.P.2
Kuang, Y.3
Mach, S.L.4
O'Connell, A.5
Messineo, M.M.6
-
41
-
-
84938399710
-
Detection and dynamic changes of egfr mutations from circulating tumor dna as a predictor of survival outcomes in nsclc patients treated with first-line intercalated erlotinib and chemotherapy
-
Mok T, Wu YL, Lee JS, Yu CJ, Sriuranpong V, Sandoval-Tan J, et al. Detection and dynamic changes of EGFR mutations from circulating tumor DNA as a predictor of survival outcomes in NSCLC patients treated with first-line intercalated erlotinib and chemotherapy. Clin Cancer Res 2015;21: 3196–203.
-
(2015)
Clin Cancer Res
, vol.21
, pp. 3196-3203
-
-
Mok, T.1
Wu, Y.L.2
Lee, J.S.3
Yu, C.J.4
Sriuranpong, V.5
Sandoval-Tan, J.6
-
42
-
-
84969257302
-
Assessment of egfr mutation status in matched plasma and tumor tissue of nsclc patients from a phase i study of rociletinib (co-1686)
-
Karlovich C, Goldman JW, Sun JM, Mann E, Sequist LV, Konopa K, et al. Assessment of EGFR mutation status in matched plasma and tumor tissue of NSCLC patients from a phase I study of rociletinib (CO-1686). Clin Cancer Res 2016;22:2386–95.
-
(2016)
Clin Cancer Res
, vol.22
, pp. 2386-2395
-
-
Karlovich, C.1
Goldman, J.W.2
Sun, J.M.3
Mann, E.4
Sequist, L.V.5
Konopa, K.6
-
43
-
-
84942521073
-
Early prediction of response to tyrosine kinase inhibitors by quantification of egfr mutations in plasma of nsclc patients
-
Marchetti A, Palma JF, Felicioni L, De Pas TM, Chiari R, Del Grammastro M, et al. Early prediction of response to tyrosine kinase inhibitors by quantification of EGFR mutations in plasma of NSCLC patients. J Thorac Oncol 2015;10:1437–43.
-
(2015)
J Thorac Oncol
, vol.10
, pp. 1437-1443
-
-
Marchetti, A.1
Palma, J.F.2
Felicioni, L.3
De Pas, T.M.4
Chiari, R.5
Del Grammastro, M.6
-
44
-
-
51349141191
-
Circulating mutant dna to assess tumor dynamics
-
Diehl F, Schmidt K, Choti MA, Romans K, Goodman S, Li M, et al. Circulating mutant DNA to assess tumor dynamics. Nat Med 2008;14: 985–90.
-
(2008)
Nat Med
, vol.14
, pp. 985-990
-
-
Diehl, F.1
Schmidt, K.2
Choti, M.A.3
Romans, K.4
Goodman, S.5
Li, M.6
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