Neonatal Immune Challenge with Lipopolysaccharide Triggers Long-lasting Sex- and Age-related Behavioral and Immune/Neurotrophic Alterations in Mice: Relevance to Autism Spectrum Disorders

Molecular Neurobiology

Volumn 55, Issue 5, 2018, Pages 3775-3788

  Custódio, Charllyany Sabino ^a   Mello, Bruna Stefânia Ferreira ^a   Filho, Adriano José Maia Chaves ^a   de Carvalho Lima, Camila Nayane ^a   Cordeiro, Rafaela Carneiro ^a   Miyajima, Fábio ^a,b   Réus, Gislaine Z ^c   Vasconcelos, Silvânia Maria Mendes ^a   Barichello, Tatiana ^d,e   Quevedo, João ^d,e   de Oliveira, Antônio Carlos ^f   de Lucena, David Freitas ^a   Macedo, Danielle S ^a,g  

^a FEDERAL UNIVERSITY OF CEARÁ   (Brazil)

^b UNIVERSITY OF LIVERPOOL   (United Kingdom)

^c UNIVERSITY OF SOUTHERN SANTA CATARINA   (Brazil)

^d UNIVERSITY OF TEXAS MEDICAL SCHOOL   (United States)

^e UNIVERSITY OF TEXAS   (United States)

^f FEDERAL UNIVERSITY OF MINAS GERAIS   (Brazil)

^g National Science and Technology Institute for Translational Medicine (INCT TM)   (Brazil)

Author keywords

Age; Autism spectrum disorder; Immune activation; Immune inflammatory alterations; Lipopolysaccharide; Sex differences

Indexed keywords

BRAIN DERIVED NEUROTROPHIC FACTOR; GAMMA INTERFERON; INTERLEUKIN 4; INTERLEUKIN 6; MYELOPEROXIDASE; NITRITE; PARVALBUMIN; LIPOPOLYSACCHARIDE;

ADULT; AGE DISTRIBUTION; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANXIETY DISORDER; ARTICLE; AUTISM; BEHAVIOR CHANGE; BRAIN LEVEL; COMPULSION; CONTROLLED STUDY; DEPRESSION; ENZYME ACTIVITY; EXPOSURE; FEMALE; FORCED SWIM TEST; HIPPOCAMPUS; HYPOTHALAMUS; IMMUNE RESPONSE; INCIDENCE; MALE; MEMORY DISORDER; MOUSE; NEWBORN; NONHUMAN; OPEN FIELD TEST; PERINATAL PERIOD; PREFRONTAL CORTEX; PREPULSE INHIBITION; PROVOCATION TEST; SEX DIFFERENCE; SOCIAL INTERACTION TEST; STARTLE REFLEX; SUCROSE PREFERENCE TEST; SWISS WEBSTER MOUSE; WORKING MEMORY; AGE; ANIMAL; ANIMAL BEHAVIOR; DISEASE MODEL; DRUG EFFECT; IMMUNOLOGY; LIPID PEROXIDATION; MAZE TEST; METABOLISM; PHYSIOLOGY; SEX FACTOR; SHORT TERM MEMORY;

AGE FACTORS; ANIMALS; AUTISM SPECTRUM DISORDER; BEHAVIOR, ANIMAL; BRAIN-DERIVED NEUROTROPHIC FACTOR; DISEASE MODELS, ANIMAL; FEMALE; HIPPOCAMPUS; HYPOTHALAMUS; LIPID PEROXIDATION; LIPOPOLYSACCHARIDES; MALE; MAZE LEARNING; MEMORY, SHORT-TERM; MICE; PREFRONTAL CORTEX; SEX FACTORS;

EID: 85019848982     PISSN: 08937648     EISSN: 15591182     Source Type: Journal    
DOI: 10.1007/s12035-017-0616-1     Document Type: Article

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