TCR crosslinking promotes Crk adaptor protein binding to tyrosine-phosphorylated CD3ζ chain

Biochemical and Biophysical Research Communications

Volumn 488, Issue 3, 2017, Pages 541-546

  Dong, Guangyu ^a,b   Kalifa, Rachel ^a,c   Nath, Pulak Ranjan ^a,d   Gelkop, Sigal ^a   Isakov, Noah ^a  

^a BEN GURION UNIVERSITY OF THE NEGEV   (Israel)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c HEBREW UNIVERSITY OF JERUSALEM   (Israel)

^d NATIONAL CANCER INSTITUTE   (United States)

Author keywords

CD3 chain; Crk adaptor proteins; Signal transduction; T cell activation; TCR CD3 crosslinking; Tyrosine phosphorylation

Indexed keywords

ADAPTOR PROTEIN; CD3 ANTIGEN; CD3 ZETA ANTIGEN; CRK ADAPTOR PROTEIN; CRK LIKE PROTEIN; CRKI ADAPTOR PROTEIN; CRKII ADAPTOR PROTEIN; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; T LYMPHOCYTE RECEPTOR; TYROSINE; UNCLASSIFIED DRUG; CRK PROTEIN, HUMAN; LYMPHOCYTE ANTIGEN RECEPTOR; ONCOPROTEIN; PHOSPHOTYROSINE; PROTEIN BINDING; PROTEIN KINASE ZAP 70;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; JURKAT CELL LINE; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CROSS LINKING; PROTEIN DOMAIN; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; BINDING SITE; CHEMISTRY; METABOLISM; TUMOR CELL CULTURE;

BINDING SITES; HUMANS; PHOSPHOTYROSINE; PROTEIN BINDING; PROTO-ONCOGENE PROTEINS C-CRK; RECEPTORS, ANTIGEN, T-CELL; TUMOR CELLS, CULTURED; ZAP-70 PROTEIN-TYROSINE KINASE;

EID: 85019790589     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2017.05.082     Document Type: Article

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