Attention-Deficit Hyperactivity and Obsessive-Compulsive Symptoms in Adult Patients With Primary Restless Legs Syndrome: Different Phenotypes of the Same Disease?

Behavioral Sleep Medicine

Volumn 17, Issue 3, 2019, Pages 246-253

  Ghorayeb, Imad ^a,b,c   Gamas, Ashley ^b,c   Mazurie, Zoé ^b,c   Mayo, Willy ^b,c  

^a BORDEAUX UNIVERSITY HOSPITAL   (France)

^b UNIVERSITÉ DE BORDEAUX   (France)

^c UMR 5287   (France)

Author keywords

[No Author keywords available]

Indexed keywords

ATTENTION DEFICIT DISORDER; COMORBIDITY; COMPLICATION; FEMALE; HUMAN; MALE; MIDDLE AGED; OBSESSIVE COMPULSIVE DISORDER; PATHOLOGY; PHENOTYPE; PREVALENCE; QUESTIONNAIRE; RESTLESS LEGS SYNDROME;

ATTENTION DEFICIT DISORDER WITH HYPERACTIVITY; COMORBIDITY; FEMALE; HUMANS; MALE; MIDDLE AGED; OBSESSIVE-COMPULSIVE DISORDER; PHENOTYPE; PREVALENCE; RESTLESS LEGS SYNDROME; SURVEYS AND QUESTIONNAIRES;

EID: 85019749269     PISSN: 15402002     EISSN: 15402010     Source Type: Journal    
DOI: 10.1080/15402002.2017.1326919     Document Type: Article

References (46)

1. Adler, L. A., Spencer, T., Faraone, S. V., Kessler, R. C., Howes, M. J., Biederman, J., & Secnik, K., (2006). Validity of pilot Adult ADHD Self-Report Scale (ASRS) to rate adult ADHD symptoms. Annals of Clinical Psychiatry, 18(3), 145–148. doi:10.1080/10401230600801077
2. Akpinar, S., (1982). Treatment of restless legs syndrome with levodopa plus benserazide. Archives of Neurology, 39(11), 739.
3. Allen, R. P., Picchietti, D. L., Garcia-Borreguero, D., Ondo, W. G., Walters, A. S., Winkelman, J. W.,… International Restless Legs Syndrome Study Group. (2014). Restless legs syndrome/Willis-Ekbom disease diagnostic criteria: Updated International Restless Legs Syndrome Study Group (IRLSSG) consensus criteria—history, rationale, description, and significance. Sleep Medicine, 15(8), 860–873. doi:10.1016/j.sleep.2014.03.025
4. American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: Author.
5. Bandelow, B., Baldwin, D., Abelli, M., Bolea-Alamanac, B., Bourin, M., Chamberlain, S. R.,… Riederer, P., (2016). Biological markers for anxiety disorders, OCD and PTSD: A consensus statement. Part II: Neurochemistry, neurophysiology and neurocognition. The World Journal of Biological Psychiatry, 1–53. doi:10.1080/15622975.2016.1190867
6. Barriere, G., Cazalets, J. R., Bioulac, B., Tison, F., & Ghorayeb, I., (2005). The restless legs syndrome. Progress in Neurobiology, 77(3), 139–165. doi:10.1016/j.pneurobio.2005.10.007
7. Bayard, S., Langenier, M. C., & Dauvilliers, Y., (2013). Decision-making, reward-seeking behaviors and dopamine agonist therapy in restless legs syndrome. Sleep, 36(10), 1501–1507. doi:10.5665/sleep.3044
8. Becker, P. M., & Sharon, D., (2014). Mood disorders in restless legs syndrome (Willis-Ekbom disease). The Journal of Clinical Psychiatry, 75(7), e679–e694. doi:10.4088/JCP.13r08692
9. Chen, Q., Beard, J. L., & Jones, B. C., (1995). Abnormal rat brain monoamine metabolism in iron deficiency anemia. The Journal of Nutritional Biochemistry, 6(9), 486–493. doi:10.1016/0955-2863(95)00074-a
10. Cho, S. J., Hong, J. P., Hahm, B. J., Jeon, H. J., Chang, S. M., Cho, M. J., & Lee, H. B., (2009). Restless legs syndrome in a community sample of Korean adults: Prevalence, impact on quality of life, and association with DSM-IV psychiatric disorders. Sleep, 32(8), 1069–1076.
11. Cortese, S., Angriman, M., Lecendreux, M., & Konofal, E., (2012). Iron and attention deficit/hyperactivity disorder: What is the empirical evidence so far? A systematic review of the literature. Expert Review of Neurotherapeutics, 12(10), 1227–1240. doi:10.1586/ern.12.116
12. Cortese, S., Konofal, E., Lecendreux, M., Arnulf, I., Mouren, M. C., Darra, F., & Dalla Bernardina, B., (2005). Restless legs syndrome and attention-deficit/hyperactivity disorder: A review of the literature. Sleep, 28(8), 1007–1013.
13. Earley, C. J., Connor, J., Garcia-Borreguero, D., Jenner, P., Winkelman, J., Zee, P. C., & Allen, R., (2014). Altered brain iron homeostasis and dopaminergic function in Restless Legs Syndrome (Willis-Ekbom Disease). Sleep Medicine, 15(11), 1288–1301. doi:10.1016/j.sleep.2014.05.009
14. Earley, C. J., Connor, J. R., Beard, J. L., Clardy, S. L., & Allen, R. P., (2005). Ferritin levels in the cerebrospinal fluid and restless legs syndrome: Effects of different clinical phenotypes. Sleep, 28(9), 1069–1075.
15. Estevez, N., Eich-Hochli, D., Dey, M., Gmel, G., Studer, J., & Mohler-Kuo, M., (2014). Prevalence of and associated factors for adult attention deficit hyperactivity disorder in young Swiss men. PLoS ONE, 9(2), e89298. doi:10.1371/journal.pone.0089298
16. Faraone, S. V., Biederman, J., & Mick, E., (2006). The age-dependent decline of attention deficit hyperactivity disorder: A meta-analysis of follow-up studies. Psychological Medicine, 36(2), 159–165. doi:10.1017/S003329170500471X
17. Fleming, D. J., Jacques, P. F., Tucker, K. L., Massaro, J. M., D’Agostino, R. B., Sr., Wilson, P. W., & Wood, R. J., (2001). Iron status of the free-living, elderly Framingham Heart Study cohort: An iron-replete population with a high prevalence of elevated iron stores. The American Journal of Clinical Nutrition, 73(3), 638–646.
18. Hantouche, E., & Guelfi, J. D., (1993). [Self-evaluation of obsessive-compulsive disorder. Adaptation and validation of two psychometric scales to the French version]. L’Encephale, 19(3), 241–248.
19. Hening, W., Allen, R., Earley, C., Kushida, C., Picchietti, D., & Silber, M., (1999). The treatment of restless legs syndrome and periodic limb movement disorder. An American Academy of Sleep Medicine Review. Sleep, 22(7), 970–999.
20. Hening, W. A., Allen, R. P., Washburn, M., Lesage, S. R., & Earley, C. J., (2009). The four diagnostic criteria for Restless Legs Syndrome are unable to exclude confounding conditions (“mimics”). Sleep Medicine, 10(9), 976–981. doi:10.1016/j.sleep.2008.09.015
21. Hodgson, R. J., & Rachman, S., (1977). Obsessional-compulsive complaints. Behaviour Research and Therapy, 15(5), 389–395. doi:0005-7967(77)90042-0 [pii]
22. Hyacinthe, C., De Deurwaerdere, P., Thiollier, T., Li, Q., Bezard, E., & Ghorayeb, I., (2015). Blood withdrawal affects iron store dynamics in primates with consequences on monoaminergic system function. Neuroscience, 290, 621–635. doi:10.1016/j.neuroscience.2015.01.057
23. Kessler, R. C., Adler, L., Ames, M., Demler, O., Faraone, S., Hiripi, E.,… Walters, E. E., (2005). The World Health Organization Adult ADHD Self-Report Scale (ASRS): A short screening scale for use in the general population. Psychological Medicine, 35(2), 245–256.
24. Kessler, R. C., Adler, L. A., Gruber, M. J., Sarawate, C. A., Spencer, T., & Van Brunt, D. L., (2007). Validity of the World Health Organization Adult ADHD Self-Report Scale (ASRS) Screener in a representative sample of health plan members. International Journal of Methods in Psychiatric Research, 16(2), 52–65. doi:10.1002/mpr.208
25. Kim, J. B., Koo, Y. S., Eun, M. Y., Park, K. W., & Jung, K. Y., (2013). Psychosomatic symptom profiles in patients with restless legs syndrome. Sleep and Breathing, 17(3), 1055–1061. doi:10.1007/s11325-013-0800-0
26. Lee, H. B., Hening, W. A., Allen, R. P., Kalaydjian, A. E., Earley, C. J., Eaton, W. W., & Lyketsos, C. G., (2008). Restless legs syndrome is associated with DSM-IV major depressive disorder and panic disorder in the community. The Journal of Neuropsychiatry and Clinical Neurosciences, 20(1), 101–105. doi:10.1176/appi.neuropsych.20.1.101
27. Marconi, S., Scarlatti, F., Rizzo, G., Antelmi, E., Innamorati, M., Pompili, M.,… Provini, F., (2015). Is nocturnal eating in restless legs syndrome linked to a specific psychopathological profile? A pilot study. Journal of Neural Transmission (Vienna), 122(11), 1563–1571. doi:10.1007/s00702-015-1435-z
28. Nelson, C., Erikson, K., Pinero, D. J., & Beard, J. L., (1997). In vivo dopamine metabolism is altered in iron-deficient anemic rats. The Journal of Nutrition, 127(12), 2282–2288.
29. Ohayon, M. M., & Roth, T., (2002). Prevalence of restless legs syndrome and periodic limb movement disorder in the general population. Journal of Psychosomatic Research, 53(1), 547–554.
30. Perez-Lloret, S., Rey, M. V., Bondon-Guitton, E., Rascol, O., Montastruc, A. J., & French Association of Regional Pharmacovigilance, C. (2012). Drugs associated with restless legs syndrome: A case/noncase study in the French Pharmacovigilance Database. Journal of Clinical Psychopharmacology, 32(6), 824–827. doi:10.1097/JCP.0b013e318272cdd8
31. Provini, F., Antelmi, E., Vignatelli, L., Zaniboni, A., Naldi, G., Calandra-Buonaura, G.,… Montagna, P., (2009). Association of restless legs syndrome with nocturnal eating: A case-control study. Movement Disorders, 24(6), 871–877. doi:10.1002/mds.22460
32. Rottach, K. G., Schaner, B. M., Kirch, M. H., Zivotofsky, A. Z., Teufel, L. M., Gallwitz, T., & Messer, T., (2008). Restless legs syndrome as side effect of second generation antidepressants. Journal of Psychiatric Research, 43(1), 70–75. doi:10.1016/j.jpsychires.2008.02.006
33. Roy, M., de Zwaan, M., Tuin, I., Philipsen, A., Brahler, E., & Muller, A., (2015). Association between restless legs syndrome and adult ADHD in a German community-based sample. Journal of Attention Disorders. doi:10.1177/1087054714561291
34. Sasson, Y., Zohar, J., Chopra, M., Lustig, M., Iancu, I., & Hendler, T., (1997). Epidemiology of obsessive-compulsive disorder: A world view [Suppl. 12]. The Journal of Clinical Psychiatry, 58, 7–10.
35. Scholz, H., Benes, H., Happe, S., Bengel, J., Kohnen, R., & Hornyak, M., (2011). Psychological distress of patients suffering from restless legs syndrome: A cross-sectional study. Health and Quality of Life Outcomes, 9, 73. doi:10.1186/1477-7525-9-73
36. Sevim, S., Dogu, O., Kaleagasi, H., Aral, M., Metin, O., & Camdeviren, H., (2004). Correlation of anxiety and depression symptoms in patients with restless legs syndrome: A population based survey. Journal of Neurology, Neurosurgery, and Psychiatry, 75(2), 226–230.
37. Snitselaar, M. A., Smits, M. G., & Spijker, J., (2015). Prevalence of restless legs syndrome in adult ADHD and its subtypes. Behavioral Sleep Medicine, 1–9. doi:10.1080/15402002.2015.1018386
38. Solanto, M. V., (1998). Neuropsychopharmacological mechanisms of stimulant drug action in attention-deficit hyperactivity disorder: A review and integration. Behavioural Brain Research, 94(1), 127–152.
39. Stein, D. J., (2000). Neurobiology of the obsessive-compulsive spectrum disorders. Biological Psychiatry, 47(4), 296–304.
40. Sternberger, L. G., & Burns, G. L., (1990). Maudsley Obsessional-Compulsive Inventory: Obsessions and compulsions in a nonclinical sample. Behaviour Research and Therapy, 28(4), 337–340.
41. Szentkiralyi, A., Volzke, H., Hoffmann, W., Baune, B. T., & Berger, K., (2013). The relationship between depressive symptoms and restless legs syndrome in two prospective cohort studies. Psychosomatic Medicine, 75(4), 359–365. doi:10.1097/PSY.0b013e31828bbbf1
42. Trautmann, E., Barke, A., Frisch, J. U., Schmidt, A. L., Kunert, F., Canelo, M.,… Trenkwalder, C., (2014). Restless legs syndrome: Psychiatric comorbidities are more important than neuroticism. Behavioral Sleep Medicine, 1–12. doi:10.1080/15402002.2014.919917
43. Unger, E. L., Bianco, L. E., Jones, B. C., Allen, R. P., & Earley, C. J., (2014). Low brain iron effects and reversibility on striatal dopamine dynamics. Experimental Neurology, 261C, 462–468. doi:10.1016/j.expneurol.2014.06.023
44. van de Glind, G., van den Brink, W., Koeter, M. W., Carpentier, P. J., van Emmerik-van Oortmerssen, K., Kaye, S.,… Levin, F. R., (2013). Validity of the Adult ADHD Self-Report Scale (ASRS) as a screener for adult ADHD in treatment seeking substance use disorder patients. Drug and Alcohol Dependence, 132(3), 587–596. doi:10.1016/j.drugalcdep.2013.04.010
45. Wagner, M. L., Walters, A. S., & Fisher, B. C., (2004). Symptoms of attention-deficit/hyperactivity disorder in adults with restless legs syndrome. Sleep, 27(8), 1499–1504.
46. Walters, A. S., LeBrocq, C., Dhar, A., Hening, W., Rosen, R., Allen, R. P.,… International Restless Legs Syndrome Study Group. (2003). Validation of the International Restless Legs Syndrome Study Group rating scale for restless legs syndrome. Sleep Medicine, 4(2), 121–132.